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Actiq Respiratory Depression Side Effects

Actiq Respiratory Depression Side Effect Reports


The following Actiq Respiratory Depression side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Respiratory Depression, can occur, and what you can do about them.

A side effect could appear soon after you start Actiq or it might take time to develop.



Depressed Level Of Consciousness, Respiratory Depression

This Respiratory Depression side effect was reported by a health professional from UNITED STATES. A 1-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Actiq (dosage: Once Buccal), which was started on Mar 18, 2008. Concurrently used drugs: NA. When starting to take Actiq the consumer reported the following symptoms:
  • Depressed Level Of Consciousness
  • Respiratory Depression
The patient was hospitalized. These side effects may potentially be related to Actiq.
Apnoea, Respiratory Depression

This Respiratory Depression Actiq side effect was reported by a health professional from UNITED KINGDOM on Jan 03, 2008. A Female , 46 years of age, was diagnosed with and was treated with Actiq. The patient presented the following health conditions:
  • Apnoea
  • Respiratory Depression
. Actiq dosage: 400 Ug Prn Sublingual. Additional drugs used at the same time:
  • Fentanyl (50 Ug Transdermal)
  • Pregabalin (225 Mg Qd)
  • Movicol /01053601/
  • Diclofenac
  • Paracetamol
  • Nifedipine
  • Citalopram Hydrobromide
  • Simvastatin
Bradypnoea, Incorrect Dose Administered, Respiratory Depression, Somnolence

This is a Actiq side effect report of a 67-year-old female patient (weight:NA) from GERMANY, suffering from the following symptoms/conditions: cancer pain, who was treated with Actiq (dosage:400-1200ug Buccal, start time: May 31, 2007), combined with:
  • Duragesic-100
  • Voltaren
  • Pregabaline
, and developed a serious reaction and a Respiratory Depression side effect. The patient presented with:
  • Bradypnoea
  • Incorrect Dose Administered
  • Respiratory Depression
  • Somnolence
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Actiq treatment in female patients suffering from cancer pain, resulting in Respiratory Depression.

Lethargy, Respiratory Depression, Somnolence, X-ray Abnormal

A 57-year-old female patient (weight: NA) from UNITED STATES with the following symptoms: NA started Actiq treatment (dosage: Buccal) on May 15, 2007. Soon after starting Actiq treatment, the consumer experienced several side effects, including:
  • Lethargy
  • Respiratory Depression
  • Somnolence
  • X-ray Abnormal
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Actiq side effects, such as Respiratory Depression.
Bradypnoea, Respiratory Depression, Somnolence

A female patient from GERMANY was prescribed and started Actiq on Jul 27, 2007. Patient felt the following Actiq side effects: bradypnoea, respiratory depression, somnolence Additional patient health information: Female , 67 years of age, The consumer reported the following symptoms: was diagnosed with and. Actiq dosage: 400-1200ug Buccal. Concurrently used drugs:
  • Duragesic-100
  • Voltaren
  • Pregabaline
The patient was hospitalized.
Agitation, Coma, Incorrect Dose Administered, Irritability, Lethargy, Pain, Respiratory Arrest, Respiratory Depression, Somnolence

This report suggests a potential Actiq Respiratory Depression side effect(s) that can have serious consequences. A 59-year-old female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Actiq (dosage: 200 Ug Unk; Buccal) starting NS. Soon after starting Actiq the patient began experiencing various side effects, including:
  • Agitation
  • Coma
  • Incorrect Dose Administered
  • Irritability
  • Lethargy
  • Pain
  • Respiratory Arrest
  • Respiratory Depression
  • Somnolence
Drugs used concurrently:NA. The patient was hospitalized. Although Actiq demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Respiratory Depression, may still occur.
Coma, Respiratory Depression

An adverse event was reported by a health professional on Apr 27, 2007 by a male taking Actiq (dosage: Unk Buccal) . Location: UNITED STATES , 19 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Actiq side effects: coma, respiratory depression. Additional medications/treatments:
Cardio-respiratory Arrest, Chest Pain, Conduction Disorder, Diarrhoea, Dyspnoea, Electrolyte Imbalance, Hypotension, Respiratory Depression, Tachycardia

This Respiratory Depression problem was reported by a health professional from . A 59-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On May 31, 2003 a consumer started treatment with Actiq (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Actiq, the patient experienced the following unwanted symptoms /side effects:
  • Cardio-respiratory Arrest
  • Chest Pain
  • Conduction Disorder
  • Diarrhoea
  • Dyspnoea
  • Electrolyte Imbalance
  • Hypotension
  • Respiratory Depression
  • Tachycardia
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Respiratory Depression, may become evident only after a product is in use by the general population.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Actiq Respiratory Depression Causes and Reviews


What is respiratory failure?

Respiratory failure is a condition in which your blood doesn't have enough oxygen or has too much carbon dioxide. Sometimes you can have both problems.

When you breathe, your lungs take in oxygen. The oxygen passes into your blood, which carries it to your organs. Your organs, such as your heart and brain, need this oxygen-rich blood to work well.

Another part of breathing is removing the carbon dioxide from the blood and breathing it out. Having too much carbon dioxide in your blood can harm your organs.

What causes respiratory failure?

Conditions that affect your breathing can cause respiratory failure. These conditions may affect the muscles, nerves, bones, or tissues that support breathing. Or they may affect the lungs directly. These conditions include

  • Lung diseases such as COPD (chronic obstructive pulmonary disease), cystic fibrosis, pneumonia, and pulmonary embolism
  • Conditions that affect the nerves and muscles that control breathing, such as amyotrophic lateral sclerosis (ALS), muscular dystrophy, spinal cord injuries, and stroke
  • Problems with the spine, such as scoliosis (a curve in the spine). They can affect the bones and muscles used for breathing.
  • Damage to the tissues and ribs around the lungs. An injury to the chest can cause this damage.
  • Drug or alcohol overdose
  • Inhalation injuries, such as from inhaling smoke (from fires) or harmful fumes
What are the symptoms of respiratory failure?

The symptoms of respiratory failure depend on the cause and the levels of oxygen and carbon dioxide in your blood.

A low oxygen level in the blood can cause shortness of breath and air hunger (the feeling that you can't breathe in enough air). Your skin, lips, and fingernails may also have a bluish color. A high carbon dioxide level can cause rapid breathing and confusion.

Some people who have respiratory failure may become very sleepy or lose consciousness. They also may have arrhythmia (irregular heartbeat). You may have these symptoms if your brain and heart are not getting enough oxygen.

How is respiratory failure diagnosed?

Your health care provider will diagnose respiratory failure based on

  • Your medical history
  • A physical exam, which often includes
    • Listening to your lungs to check for abnormal sounds
    • Listening to your heart to check for arrhythmia
    • Looking for a bluish color on your skin, lips, and fingernails
  • Diagnostic tests, such as
    • Pulse oximetry, a small sensor that uses a light to measure how much oxygen is in your blood. The sensor goes on the end of your finger or on your ear.
    • Arterial blood gas test, a test that measures the oxygen and carbon dioxide levels in your blood. The blood sample is taken from an artery, usually in your wrist.

Once you are diagnosed with respiratory failure, your provider will look for what is causing it. Tests for this often include a chest x-ray. If your provider thinks you may have arrhythmia because of the respiratory failure, you may have an EKG (electrocardiogram). This is simple, painless test that detects and records your heart's electrical activity.

What are the treatments for respiratory failure?

Treatment for respiratory failure depends on

  • Whether it is acute (short-term) or chronic (ongoing)
  • How severe it is
  • What is causing it

Acute respiratory failure can be a medical emergency. You may need treatment in intensive care unit at a hospital. Chronic respiratory failure can often be treated at home. But if your chronic respiratory failure is severe, you might need treatment in a long-term care center.

One of the main goals of treatment is to get oxygen to your lungs and other organs and remove carbon dioxide from your body. Another goal is to treat the cause of the condition. Treatments may include

  • Oxygen therapy, through a nasal cannula (two small plastic tubes that go in your nostrils) or through a mask that fits over your nose and mouth
  • Tracheostomy, a surgically-made hole that goes through the front of your neck and into your windpipe. A breathing tube, also called a tracheostomy, or trach tube, is placed in the hole to help you breathe.
  • Ventilator, a breathing machine that blows air into your lungs. It also carries carbon dioxide out of your lungs.
  • Other breathing treatments, such as noninvasive positive pressure ventilation (NPPV), which uses mild air pressure to keep your airways open while you sleep. Another treatment is a special bed that rocks back and forth, to help you breathe in and out.
  • Fluids, often through an intravenous (IV), to improve blood flow throughout your body. They also provide nutrition.
  • Medicines for discomfort
  • Treatments for the cause of the respiratory failure. These treatments may include medicines and procedures.

If you have respiratory failure, see your health care provider for ongoing medical care. Your provider may suggest pulmonary rehabilitation.

If your respiratory failure is chronic, make sure that you know when and where to get help for your symptoms. You need emergency care if you have severe symptoms, such as trouble catching your breath or talking. You should call your provider if you notice that your symptoms are worsening or if you have new signs and symptoms.

Living with respiratory failure may cause fear, anxiety, depression, and stress. Talk therapy, medicines, and support groups can help you feel better.

NIH: National Heart, Lung, and Blood Institute


Actiq Respiratory Depression Reviews

Fri, 20 Aug 2010
My mom, aged 77, just completed her 3rd ipi infusion Wed 8/18. It started in her lungs. Brain metastisis with removal of one tumor June 9, 2010. 4-5 small tumors still. She's not 100% mentally alert, but she tells us the pain from the tumors on her upper thign feel like blistering sunburn. She has not been eating lately, only drinking boost. Her oncologist is treating the pain on her legs wtih lidocaine patches and that seems to help. She also has a fentanyl patch on her arm and uses Actiq 'lollipops's for pain control.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Actiq Side Effects

Somnolence (67)
Off Label Use (59)
Dental Caries (55)
Pain (44)
Vomiting (33)
Lethargy (33)
Overdose (30)
Nausea (29)
Death (29)
Tooth Loss (25)
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Loss Of Consciousness (20)
Confusional State (20)
Tooth Disorder (19)
Fatigue (18)
Dependence (17)
Coma (16)
Accidental Overdose (16)
Convulsion (16)
Dyspnoea (16)
Incorrect Dose Administered (15)
Depression (14)
Hypotension (14)
Fall (13)
Diarrhoea (13)
Dehydration (13)
Withdrawal Syndrome (12)
Accidental Exposure (12)
Tachycardia (12)
Cardiac Arrest (12)
Weight Decreased (12)
Suicidal Ideation (11)
Hallucination (10)
Dry Mouth (10)
Insomnia (9)
Malignant Neoplasm Progression (9)
Pneumonia (9)
Respiratory Arrest (9)
Miosis (9)
Amnesia (9)
Anxiety (9)
Abnormal Behaviour (9)
Dysarthria (9)
Agitation (9)
Respiratory Depression (8)
Mental Status Changes (8)
Treatment Noncompliance (8)
Hyperhidrosis (8)
Malaise (8)
Tremor (8)

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