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Acyclovir Hepatotoxicity Side Effects

Acyclovir Hepatotoxicity Side Effect Reports


The following Acyclovir Hepatotoxicity side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Hepatotoxicity, can occur, and what you can do about them.

A side effect could appear soon after you start Acyclovir or it might take time to develop.



Liver Function Test Abnormal, Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Venoocclusive Disease, Blood Bilirubin Increased, Alanine Aminotransferase Increased

This Hepatotoxicity side effect was reported by a health professional from GB. A 19-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Acyclovir (dosage: NA), which was started on Sep 21, 2007. Concurrently used drugs:
  • Ondansetron Hydrochloride
  • Acetaminophen
  • Allopurinol
  • Morphine
  • Chlorpheniramine Maleate
  • Norethisterone (5 Mg, 3 In 1 D)
  • Cyclosporin
  • Caspofungin (70 Mg, 1 In 1 D)
When starting to take Acyclovir the consumer reported the following symptoms:
  • Liver Function Test Abnormal
  • Dilatation Intrahepatic Duct Acquired
  • Hepatotoxicity
  • Venoocclusive Disease
  • Blood Bilirubin Increased
  • Alanine Aminotransferase Increased
These side effects may potentially be related to Acyclovir.
Hepatotoxicity, Nausea, Vomiting, Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased, Brucellosis, Nervous System Disorder

This Hepatotoxicity Acyclovir side effect was reported by a consumer or non-health professional from IR on Jan 23, 2013. A Female , 36 years of age, was diagnosed with and was treated with Acyclovir. The patient presented the following health conditions:
  • Hepatotoxicity
  • Nausea
  • Vomiting
  • Aspartate Aminotransferase Increased
  • Alanine Aminotransferase Increased
  • Brucellosis
  • Nervous System Disorder
. Acyclovir dosage: NA. Additional drugs used at the same time: NA.
Hepatotoxicity, Nausea, Brucellosis

This is a Acyclovir /00587301/ (acyclovir) side effect report of a 36-year-old female patient (weight:NA) from IR, suffering from the following symptoms/conditions: encephalitis, who was treated with Acyclovir /00587301/ (acyclovir) (dosage:NA, start time: NS), combined with: NA., and developed a serious reaction and a Hepatotoxicity side effect. The patient presented with:
  • Hepatotoxicity
  • Nausea
  • Brucellosis
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Acyclovir /00587301/ (acyclovir) treatment in female patients suffering from encephalitis, resulting in Hepatotoxicity.

Hepatotoxicity, Blood Bilirubin Increased, Oedema, Nausea, Pyrexia

A 33-year-old patient (weight: NA) from GERMANY with the following symptoms: antiviral prophylaxis,bone marrow conditioning regimen,prophylaxis against graft versus host disease started Acyclovir treatment (dosage: NA) on NS. Soon after starting Acyclovir treatment, the consumer experienced several side effects, including:
  • Hepatotoxicity
  • Blood Bilirubin Increased
  • Oedema
  • Nausea
  • Pyrexia
. Concurrently used drugs:
  • Cyclophosphamide
  • Cyclosporine
  • Thymoglobulin
  • Mycophenolate Mofetil
  • Fluconazole
  • Metronidazole
  • Clofarabine
  • Levofloxacin
This finding indicates that some patients can be more vulnerable to developing Acyclovir side effects, such as Hepatotoxicity.
Hepatotoxicity, Oedema, Palmar-plantar Erythrodysaesthesia Syndrome, Pyrexia

A patient from GERMANY was prescribed and started Acyclovir on Mar 08, 2012. Patient felt the following Acyclovir side effects: hepatotoxicity, oedema, palmar-plantar erythrodysaesthesia syndrome, pyrexia Additional patient health information: male , 59 years of age, The consumer reported the following symptoms: was diagnosed with and. Acyclovir dosage: NA. Concurrently used drugs:
  • Fluconazole
  • Levofloxacin
  • Clofarabine
  • Cytarabine
  • Cyclophosphamide
  • Rabbit Antithymocyte Globulin
  • Metronidazole
  • Mycophenolate Mofetil
Hepatotoxicity, Presyncope

This report suggests a potential Acyclovir Hepatotoxicity side effect(s) that can have serious consequences. A 61-year-old female patient from GERMANY (weight:NA) was diagnosed with the following health condition(s): NA and used Acyclovir (dosage: 400 Milligram) starting Mar 07, 2011. Soon after starting Acyclovir the patient began experiencing various side effects, including:
  • Hepatotoxicity
  • Presyncope
Drugs used concurrently:
  • Valoron (60 Milligram)
  • Enoxaparin Sodium (.4 Milliliter)
  • Lyrica (50 Milligram)
  • Revlimid (25 Milligram)
  • Soventol Gel
  • Moviprep (2 Dosage Forms)
  • Enalapril Maleate (10 Milligram)
  • Allopurinol (300 Milligram)
Although Acyclovir demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hepatotoxicity, may still occur.
Presyncope, Hepatotoxicity

An adverse event was reported by a physician on Sep 07, 2011 by a Female taking Acyclovir (dosage: 400 Milligram) . Location: GERMANY , 61 years of age, weighting 156.5 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Acyclovir side effects: presyncope, hepatotoxicity. Additional medications/treatments:
Associated medications used:
  • Pantoprazole (40 Milligram)
  • Torsemide (10 Milligram)
  • Valoron (4x20a?)
  • Enoxaparin Sodium (.4 Milliliter)
  • Moviprep (2 Dosage Forms)
  • Amitriptyline Hcl (25 Milligram)
  • Allopurinol (300 Milligram)
  • Folsan (5 Milligram)
Alanine Aminotransferase Increased, Blood Bilirubin Increased, Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Pain, Venoocclusive Liver Disease

This Hepatotoxicity problem was reported by a health professional from UNITED KINGDOM. A 19-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Sep 21, 2007 a consumer started treatment with Acyclovir (dosage: NA). The following drugs/medications were being taken at the same time:
  • Ondansetron (8 Mg Milligram(s) (1 Day);)
  • Caspofungin Acetate (70 Mg Milligram(s); Intravenous)
  • Omeprazole
  • Allopurinol (Oral)
  • Chlorpheniramine Maleate (10 Mg Milligram(s), (1 Day), Intravenous)
  • Cyclosporine
  • Etopophos Preservative Free (Intravenous)
  • Ketalar
When commencing Acyclovir, the patient experienced the following unwanted symptoms /side effects:
  • Alanine Aminotransferase Increased
  • Blood Bilirubin Increased
  • Dilatation Intrahepatic Duct Acquired
  • Hepatotoxicity
  • Pain
  • Venoocclusive Liver Disease
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Hepatotoxicity, may become evident only after a product is in use by the general population.
Hepatotoxicity, Venoocclusive Disease

This is a Acyclovir Tablets, 800 Mg (purepac) (acyclovir) side effect report of a 19-year-old female patient (weight: NA) from DENMARK. The patient developed the following symptoms/conditions: NA and was treated with Acyclovir Tablets, 800 Mg (purepac) (acyclovir) (dosage: NA) starting Sep 21, 2007. Concurrently used drugs:
  • Feverall (;iv)
  • Paregoric Liquid Usp (alpharma) (paregoric) (; Iv)
  • Ondansetron (8 Mg;tid; Iv)
  • Omeprazole
  • Cyclosporine
  • Allopurinol (300 Mg;qd; Po)
  • Voriconazole (200 Mg;bid;po)
  • Norethisterone (norethisterone) (5 Mg;tid; Po)
Soon after that, the consumer experienced the following of symptoms:
  • Hepatotoxicity
  • Venoocclusive Disease
This opens a possibility that Acyclovir Tablets, 800 Mg (purepac) (acyclovir) could cause Hepatotoxicity and that some female patients may be more susceptible.
Alanine Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Bilirubin Increased, Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Liver Function Test Abnormal, Venoocclusive Disease

This Hepatotoxicity side effect was reported by a health professional from DENMARK on Sep 09, 2010. A female patient from DENMARK , 19 years of age, was treated with Acyclovir. Directly after treatment started, patient experienced the unwanted or unexpected Acyclovir side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, dilatation intrahepatic duct acquired, hepatotoxicity, liver function test abnormal, venoocclusive disease. Acyclovir dosage: NA.
Associated medications used:
  • Feverall (Iv)
  • Paregoric Liquid Usp (alpharma) (paregoric)
  • Ondansetron (8 Mg;tid;iv)
  • Omeprazole
  • Cyclosporine
  • Allopurinol (300 Mg;qd;po)
  • Voriconazole (200 Mg;bid;po)
  • Norethisterone (norethisterone) (5 Mg;tid;po)
These side effects may potentially be related to Acyclovir.
Alanine Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Bilirubin Increased, Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Pain, Venoocclusive Liver Disease

This Hepatotoxicity side effect was reported by a consumer or non-health professional from UNITED KINGDOM. A 19-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Acyclovir (dosage: NA), which was started on Sep 21, 2007. Concurrently used drugs:
  • Omeprazole
  • Allopurinol (300 Mg; Qd Po)
  • Caspofungin (caspofungin) (70 Mg; Qd Iv)
  • Chlorpheniramine Maleate (10 Mg; Qid Iv)
  • Cyclosporine
  • Etopophos Preservative Free (4650 Mg; Iv)
  • Ketalar
  • Morphine (Iv)
When starting to take Acyclovir the consumer reported the following symptoms:
  • Alanine Aminotransferase Increased
  • Blood Alkaline Phosphatase Increased
  • Blood Bilirubin Increased
  • Dilatation Intrahepatic Duct Acquired
  • Hepatotoxicity
  • Pain
  • Venoocclusive Liver Disease
These side effects may potentially be related to Acyclovir.
Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Venoocclusive Liver Disease

This Hepatotoxicity Acyclovir side effect was reported by a health professional from UNITED KINGDOM on Sep 09, 2010. A Female , 19 years of age, was treated with Acyclovir. The patient presented the following health conditions:
  • Dilatation Intrahepatic Duct Acquired
  • Hepatotoxicity
  • Venoocclusive Liver Disease
. Acyclovir dosage: NA. Additional drugs used at the same time:
  • Ondansetron (8 Mg Milligram(s) I Day)
  • Caspofungin Acetate (70 Mg Milligram(s))
  • Omeprazole
  • Allopurinol
  • Chlorpheniramine Maleate (10 Mg Milligram(s) (1 Day))
  • Cyclosporine
  • Etopophos Preservative Free
  • Ketalar
Alanine Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Bilirubin Increased, Bone Marrow Transplant, Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Venoocclusive Liver Disease

This is a Acyclovir side effect report of a 22-year-old female patient (weight:NA) from UNITED KINGDOM, suffering from the following symptoms/conditions: NA, who was treated with Acyclovir (dosage:NA, start time: Sep 21, 2007), combined with:
  • Ondansetron (8 Mg Milligram(s), 1 Day,)
  • Allopurinol (Oral)
  • Caspofungin Acetate (70 Mg Milligram(s), Intravenous)
  • Chlorpheniramine Maleate (10 Mg Milligram(s), 1 Day, Intravenous)
  • Cyclosporine
  • Etopophos Preservative Free (Intravenous)
  • Ketalar
  • Morphine (Intravenous)
, and developed a serious reaction and a Hepatotoxicity side effect. The patient presented with:
  • Alanine Aminotransferase Increased
  • Blood Alkaline Phosphatase Increased
  • Blood Bilirubin Increased
  • Bone Marrow Transplant
  • Dilatation Intrahepatic Duct Acquired
  • Hepatotoxicity
  • Venoocclusive Liver Disease
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Acyclovir treatment in female patients suffering from NA, resulting in Hepatotoxicity.
Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Liver Function Test Abnormal, Venoocclusive Disease

A 19-year-old female patient (weight: NA) from UNITED KINGDOM with the following symptoms: NA started Acyclovir treatment (dosage: NA) on Sep 15, 2007. Soon after starting Acyclovir treatment, the consumer experienced several side effects, including:
  • Dilatation Intrahepatic Duct Acquired
  • Hepatotoxicity
  • Liver Function Test Abnormal
  • Venoocclusive Disease
. Concurrently used drugs:
  • Allopurinol (300 Mg; 1days; Oral)
  • Caspofungin (caspofungin) (70 Mg; Daily; Intravenous)
  • Chlorpheniramine Maleate (10 Mg; 4 Times A Day; Intravenous)
  • Cyclosporine
  • Etoposide (Intravenous)
  • Ketalar (6 Ml; Every Hour; Intravenous)
  • Morphine (Intravenous)
  • Norethisterone (norethisterone) (5 Mg; 3 Times A Day; Oral)
This finding indicates that some patients can be more vulnerable to developing Acyclovir side effects, such as Hepatotoxicity.
Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Venoocclusive Liver Disease

A female patient from UNITED KINGDOM was prescribed and started Acyclovir on Nov 19, 2007. After Acyclovir was administered, patient encountered several Acyclovir side effects: dilatation intrahepatic duct acquired, hepatotoxicity, venoocclusive liver disease Additional patient health information: Female , 19 years of age, The consumer reported the following symptoms: . Acyclovir dosage: NA. Concurrently used drugs:
  • Cyclosporine
  • Etoposide (Intravenous)
  • Ketalar (6 Ml; Every Hour; Intravenous)
  • Morphine (Intravenous)
  • Norethisterone (norethisterone) (5 Mg; Oral ; 3 Times A Day)
  • Omeprazole (8 Mg; Intravenous; 3 Times A Day)
  • Ondansetron Hcl (8 Mg; 3 Times A Day, Intravenous)
  • Acetaminophen (Intravenous)
Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Liver Function Test Abnormal, Venoocclusive Disease

This report suggests a potential Acyclovir Hepatotoxicity side effect(s) that can have serious consequences. A 19-year-old female patient from UNITED KINGDOM (weight:NA) was diagnosed with the following health condition(s): NA and used Acyclovir (dosage: NA) starting Sep 15, 2007. Soon after starting Acyclovir the patient began experiencing various side effects, including:
  • Dilatation Intrahepatic Duct Acquired
  • Hepatotoxicity
  • Liver Function Test Abnormal
  • Venoocclusive Disease
Drugs used concurrently:
  • Allopurinol (300 Mg;1days;oral)
  • Caspofungin (caspofungin) (70 Mg;daily;intravenous)
  • Chlorphenamine (chlorphenamine) (10 Mg;4 Times A Day; Intravenous)
  • Cyclosporine
  • Etoposide (Intravenous)
  • Ketalar (6 Ml;every Hour; Intravenous)
  • Morphine (Intravenous)
  • Norethisterone (norethisterone) (5 Mg;3 Times A Day;oral)
Although Acyclovir demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hepatotoxicity, may still occur.
Alanine Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Bilirubin Increased, Bone Marrow Transplant, Dilatation Intrahepatic Duct Acquired, Hepatotoxicity, Venoocclusive Disease

An adverse event was reported by a pharmacist on Nov 16, 2007 by a Female taking Acyclovir (dosage: NA) . Location: UNITED KINGDOM , 19 years of age, patient began experiencing various side effects, including: Patient felt the following Acyclovir side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, bone marrow transplant, dilatation intrahepatic duct acquired, hepatotoxicity, venoocclusive disease. Additional medications/treatments:
Multiple prescriptions taken:
  • Ketalar
  • Norethisterone
  • Cyclosporine
  • Caspofungin
  • Omeprazole
  • Tazocin
  • Voriconazole
  • Paracetamol

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Acyclovir Hepatotoxicity Causes and Reviews


In the early 1980s, when the HIV/AIDS epidemic began, patients rarely lived longer than a few years. But today, there are many effective medicines to fight the infection, and people with HIV have longer, healthier lives.

There are five major types of medicines:

  • Reverse transcriptase (RT) inhibitors - interfere with a critical step during the HIV life cycle and keep the virus from making copies of itself
  • Protease inhibitors - interfere with a protein that HIV uses to make infectious viral particles
  • Fusion inhibitors - block the virus from entering the body's cells
  • Integrase inhibitors - block an enzyme HIV needs to make copies of itself
  • Multidrug combinations - combine two or more different types of drugs into one

These medicines help people with HIV, but they are not perfect. They do not cure HIV/AIDS. People with HIV infection still have the virus in their bodies. They can still spread HIV to others through unprotected sex and needle sharing, even when they are taking their medicines.

NIH: National Institute of Allergy and Infectious Diseases


Acyclovir Hepatotoxicity Reviews

Thu, 08 Apr 2010

I get Avastin every 21 days. I get a severely swollen tongue about 1 week after treatment, sometimes only after one or two days. Is it a side effect of Avastin, or is it the combination of the drugs I am taking? Gabapentin, FAmotidine, Acyclovir, Meloxicam. I have lung cancer, am in remission. Thank you for your help!

Fri, 20 Aug 2010

I HAD HERPES ZOSTER SINCE 10 DAYS. THE BLISTERS ARE ALMOST
IN HEALING STAGE. BUT THE BURNING SENSATION IN THE NEARBY SPOTS
ARE STILL UNBEARABLE. I HAVE BEEN TREATED WITH ACYCLOVIR AND CROCIN
PL. ADVISE FOR THE BURNING SENSATION

Sat, 17 Dec 2011

14 month old girl developed erythematous skin lasion on left cheek 5 days post prevnar vaccine. 24 hrs later lesion weeping straw colored fluid and crusted. seen at pediatrician 7 days post prevnar vaccine and also diagnosed with ear infection. Started on 10 days of augmentin for ear infection and bactroban for skin lesion and Acyclovir because cannot rule out HSV of skin

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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