Amitriptyline Agitation Side Effect Reports


The following Amitriptyline Agitation side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Agitation, can occur, and what you can do about them.

A side effect could appear soon after you start Amitriptyline or it might take time to develop.


Agitation, Aggression, Condition Aggravated

This Agitation side effect was reported by a consumer or non-health professional from GB. A 33-year-old female patient (weight:NA) experienced the following symptoms/conditions: cystitis interstitial. The patient was prescribed Amitriptyline (dosage: Increased To 100ml), which was started on 2013. Concurrently used drugs: NA. When starting to take Amitriptyline the consumer reported the following symptoms:
  • Agitation
  • Aggression
  • Condition Aggravated
These side effects may potentially be related to Amitriptyline.
Panic Reaction, Agitation, Depressed Mood

This Agitation Amitriptyline side effect was reported by a consumer or non-health professional from GB on Feb 10, 2014. A Female , weighting 99.21 lb, was treated with Amitriptyline. The patient presented the following health conditions:
  • Panic Reaction
  • Agitation
  • Depressed Mood
. Amitriptyline dosage: NA. Additional drugs used at the same time:
  • Hydroxychloroquine Sulfate (watson Laboratories) (200 Mg, Daily)
Suicidal Ideation, Somnolence, Agitation, Irritability

This is a Amitriptyline side effect report of a 44-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: depression, who was treated with Amitriptyline (dosage:NA, start time: NS), combined with: NA., and developed a serious reaction and a Agitation side effect. The patient presented with:
  • Suicidal Ideation
  • Somnolence
  • Agitation
  • Irritability
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Amitriptyline treatment in female patients suffering from depression, resulting in Agitation.
Serotonin Syndrome, Agitation, Anxiety, Decreased Appetite, Hallucinations, Mixed, Blood Sodium Decreased, Cyanosis, Vision Blurred, Cogwheel Rigidity

A 27-year-old female patient (weight: NA) from GB with the following symptoms: muscle spasms,neuralgia,neck pain started Amitriptyline treatment (dosage: 25 Milligram Daily; At Night) on 1995. Soon after starting Amitriptyline treatment, the consumer experienced several side effects, including:
  • Serotonin Syndrome
  • Agitation
  • Anxiety
  • Decreased Appetite
  • Hallucinations, Mixed
  • Blood Sodium Decreased
  • Cyanosis
  • Vision Blurred
  • Cogwheel Rigidity
. Concurrently used drugs: NA.The patient was hospitalized and became disabled. This finding indicates that some patients can be more vulnerable to developing Amitriptyline side effects, such as Agitation.
Dysarthria, Muscle Rigidity, Disorientation, Agitation, Delirium, Ataxia, Somnolence, Constipation

A patient from DE was prescribed and started Amitriptyline Hydrochloride on Aug 01, 2013. Patient felt the following Amitriptyline side effects: dysarthria, muscle rigidity, disorientation, agitation, delirium, ataxia, somnolence, constipation Additional patient health information: male , 73 years of age, The consumer reported the following symptoms: was diagnosed with and. Amitriptyline Hydrochloride dosage: 150 Mg, Qd. Concurrently used drugs:
  • Valproic Acid (1200 Mg, Qd)
Anxiety, Abnormal Dreams, Palpitations, Bruxism, Agitation

This report suggests a potential Amitriptyline Hcl Agitation side effect(s) that can have serious consequences. A 40-year-old female patient from UNITED KINGDOM (weight:NA) was diagnosed with the following health condition(s): NA and used Amitriptyline Hcl (dosage: NA) starting Jan 01, 2012. Soon after starting Amitriptyline Hcl the patient began experiencing various side effects, including:
  • Anxiety
  • Abnormal Dreams
  • Palpitations
  • Bruxism
  • Agitation
Drugs used concurrently:NA. The patient was hospitalized. Although Amitriptyline Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Agitation, may still occur.
Status Epilepticus, Agitation, Polyuria, Metabolic Disorder, Metabolic Acidosis, Depressed Level Of Consciousness, Overdose, Hypokalaemia

An adverse event was reported by a physician on Mar 13, 2012 by a Female taking Amitriptyline Hcl (dosage: NA) . Location: UNITED KINGDOM , 22 years of age, weighting 101.4 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Amitriptyline side effects: status epilepticus, agitation, polyuria, metabolic disorder, metabolic acidosis, depressed level of consciousness, overdose, hypokalaemia. Additional medications/treatments:
Associated medications used:
  • Zonisamide
  • Zonisamide
  • Zonisamide
Attention Deficit/hyperactivity Disorder, Asthma, Restlessness, Agitation, Bipolar Disorder, Insomnia, Nail Picking, Tic

This Agitation problem was reported by a consumer or non-health professional from BRAZIL. A 11-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Amitriptyline Hydrochloride (dosage: NA). The following drugs/medications were being taken at the same time:
  • Risperidone
  • Depakene (1 Tablet In The Morning Half Tablet At Night)
  • Ritalin La
  • Ritalin
When commencing Amitriptyline Hydrochloride, the patient experienced the following unwanted symptoms /side effects:
  • Attention Deficit/hyperactivity Disorder
  • Asthma
  • Restlessness
  • Agitation
  • Bipolar Disorder
  • Insomnia
  • Nail Picking
  • Tic
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Agitation, may become evident only after a product is in use by the general population.
Aggression, Self-injurious Ideation, Agitation

This is a Amitriptyline Hcl side effect report of a 28-year-old patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Amitriptyline Hcl (dosage: NA) starting NS. Concurrently used drugs:
  • Tylenol Pm (70 To 80 Tablets)
  • Acetaminophen
  • Acetaminophen
  • Heroin
Soon after that, the consumer experienced the following of symptoms:
  • Aggression
  • Self-injurious Ideation
  • Agitation
The patient was hospitalized. This opens a possibility that Amitriptyline Hcl could cause Agitation and that some patients may be more susceptible.
Hallucination, Anger, Frustration, Suicidal Ideation, Irritability, Agitation

This Agitation side effect was reported by a consumer or non-health professional from UNITED STATES on Sep 28, 2011. A female patient from UNITED STATES , weighting 145.0 lb, was diagnosed with and was treated with Amitriptyline. Directly after treatment started, patient experienced the unwanted or unexpected Amitriptyline side effects: hallucination, anger, frustration, suicidal ideation, irritability, agitation. Amitriptyline dosage: 100 Mg, 1x/day.
Associated medications used:
  • Xanax (1 Mg, 1x/day)
These side effects may potentially be related to Amitriptyline.
Qrs Axis Abnormal, Toxicity To Various Agents, Sinus Tachycardia, Left Ventricular Hypertrophy, Somnolence, Agitation, Aggression, Bundle Branch Block Right

This Agitation side effect was reported by a health professional from FRANCE. A 48-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Amitriptyline Hcl (dosage: 20 Mg, Single), which was started on Dec 08, 2010. Concurrently used drugs:
  • Fluticasone Furoate (Unk)
  • Diprosone (Unk)
  • Lyrica (Unk)
  • Tramadol Hydrochloride (Unk)
  • Cymbalta (Unk)
  • Omeprazole (Unk)
  • Tercian (Unk)
  • Polyvidone (Unk)
When starting to take Amitriptyline Hcl the consumer reported the following symptoms:
  • Qrs Axis Abnormal
  • Toxicity To Various Agents
  • Sinus Tachycardia
  • Left Ventricular Hypertrophy
  • Somnolence
  • Agitation
  • Aggression
  • Bundle Branch Block Right
The patient was hospitalized. These side effects may potentially be related to Amitriptyline Hcl.
Intestinal Dilatation, Pyrexia, Headache, Multi-organ Failure, Metabolic Acidosis, Hepatic Enzyme Increased, Sepsis, Agitation

This Agitation Amitriptyline Hcl side effect was reported by a physician from NORWAY on Jul 01, 2011. A male , 59 years of age, was treated with Amitriptyline Hcl. The patient presented the following health conditions:
  • Intestinal Dilatation
  • Pyrexia
  • Headache
  • Multi-organ Failure
  • Metabolic Acidosis
  • Hepatic Enzyme Increased
  • Sepsis
  • Agitation
. Amitriptyline Hcl dosage: 125 Mg (125 Mg, 1 In 1 D),. Additional drugs used at the same time:
  • Bendroflumethiazide (bendroflumethiazide)
  • Isosorbide Mononitrate
  • Alprazolam
  • Atenolol
  • Mirtazapine (60 Mg (60 Mg, 1 In 1 D), Oral)
The patient was hospitalized.
Tremor, Balance Disorder, Paraesthesia Oral, Respiration Abnormal, Agitation, Heart Rate Increased, Dry Mouth, Anxiety

This is a Amitriptyline side effect report of a female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: sleep disorder,depression,epilepsy,convulsion, who was treated with Amitriptyline (dosage:NA, start time: Apr 14, 2011), combined with: NA., and developed a serious reaction and a Agitation side effect. The patient presented with:
  • Tremor
  • Balance Disorder
  • Paraesthesia Oral
  • Respiration Abnormal
  • Agitation
  • Heart Rate Increased
  • Dry Mouth
  • Anxiety
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Amitriptyline treatment in female patients suffering from sleep disorder,depression,epilepsy,convulsion, resulting in Agitation.
Palpitations, Malaise, Injection Site Pain, Product Quality Issue, Agitation

A 58-year-old female patient (weight: NA) from UNITED STATES with the following symptoms: NA started Amitriptyline treatment (dosage: NA) on Jan 01, 2011. Soon after starting Amitriptyline treatment, the consumer experienced several side effects, including:
  • Palpitations
  • Malaise
  • Injection Site Pain
  • Product Quality Issue
  • Agitation
. Concurrently used drugs:
  • Levothyroxine Sodium
  • Lipitor
  • Prednisone
  • Effexor
  • Fludrocortisone
  • Dexamethasone Sodium Phosphate (1 Ml/4mg Intramuscular)
This finding indicates that some patients can be more vulnerable to developing Amitriptyline side effects, such as Agitation.
Abnormal Behaviour, Confusional State, Anxiety, Delusion, Disturbance In Attention, Agitation, Memory Impairment, Anosognosia, Disorientation

A patient from UNITED KINGDOM was prescribed and started Amitriptyline on Mar 31, 2011. After Amitriptyline was administered, patient encountered several Amitriptyline side effects: abnormal behaviour, confusional state, anxiety, delusion, disturbance in attention, agitation, memory impairment, anosognosia, disorientation Additional patient health information: male , 44 years of age, The consumer reported the following symptoms: . Amitriptyline dosage: 100 Mg, Qd. Concurrently used drugs:
  • Haloperidol Decanoate (100 Mg, Qw4)
  • Levomepromazine (100 Mg, Qd)
  • Biperiden Hydrochloride Tab (6 Mg, Qd)
  • Diazepam (20 Mg, Qd)
  • Haloperidol (10 Mg, Qd)
The patient was hospitalized.
Agitation, Insomnia, Product Substitution Issue

This report suggests a potential Amitriptyline Agitation side effect(s) that can have serious consequences. A 63-year-old patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): tinnitus and used Amitriptyline (dosage: 25 Mg Qhs Po) starting Apr 01, 2007. Soon after starting Amitriptyline the patient began experiencing various side effects, including:
  • Agitation
  • Insomnia
  • Product Substitution Issue
Drugs used concurrently:NA. Although Amitriptyline demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Agitation, may still occur.
Agitation, Malaise, Cognitive Disorder, Amnesia

An adverse event was reported by a health professional on Jan 10, 2011 by a Female taking Amitriptyline (dosage: 5 Mg, 1x/day) . Location: UNITED KINGDOM , 56 years of age, weighting 154.3 lb, patient began experiencing various side effects, including: Patient felt the following Amitriptyline side effects: agitation, malaise, cognitive disorder, amnesia. Additional medications/treatments:
Multiple prescriptions taken:
  • Sulfasalazine (1 G, 2x/day)
  • Ezetimibe (10 Mg, 1x/day)
  • Naproxen (500 Mg, 2x/day)
  • Folic Acid (5 Mg Three Times Weekly)
  • Pantoprazole (40 Mg, 1x/day)
  • Methotrexate (25 Mg, Weekly)
  • Co-codamol (2 Df, 4x/day)
The patient was hospitalized.
Agitation, Depressed Level Of Consciousness, Disseminated Intravascular Coagulation, Dysstasia, Fatigue, Gastrointestinal Disorder, Headache, Hepatic Enzyme Increased

This Agitation problem was reported by a health professional from NORWAY. A 59-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Amitriptyline (ngx) (dosage: 125 Mg, Qd). The following drugs/medications were being taken at the same time:
  • Mirtazapine (ngx) (60 Mg, Qd)
  • Alprazolam (4 Mg, Qd)
  • Atenolol
  • Bendroflumethiazide
  • Isosorbide Mononitrate
When commencing Amitriptyline (ngx), the patient experienced the following unwanted symptoms /side effects:
  • Agitation
  • Depressed Level Of Consciousness
  • Disseminated Intravascular Coagulation
  • Dysstasia
  • Fatigue
  • Gastrointestinal Disorder
  • Headache
  • Hepatic Enzyme Increased
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Agitation, may become evident only after a product is in use by the general population.
Abdominal Discomfort, Abdominal Tenderness, Agitation, Atelectasis, Electrocardiogram Abnormal, Electrocardiogram St Segment Elevation, Electrocardiogram T Wave Inversion, Intention Tremor

This is a Amitriptyline Tablet 10 Mg (no Pref. Name) side effect report of a 40-year-old patient (weight: NA) from UNITED KINGDOM. The patient developed the following symptoms/conditions: NA and was treated with Amitriptyline Tablet 10 Mg (no Pref. Name) (dosage: NA) starting NS. Concurrently used drugs:
  • Olanzapine
  • Alimemazine (no Pref. Name)
Soon after that, the consumer experienced the following of symptoms:
  • Abdominal Discomfort
  • Abdominal Tenderness
  • Agitation
  • Atelectasis
  • Electrocardiogram Abnormal
  • Electrocardiogram St Segment Elevation
  • Electrocardiogram T Wave Inversion
  • Intention Tremor
The patient was hospitalized. This opens a possibility that Amitriptyline Tablet 10 Mg (no Pref. Name) could cause Agitation and that some patients may be more susceptible.
Abdominal Discomfort, Abdominal Tenderness, Agitation, Brugada Syndrome, Intention Tremor, Moaning, Nystagmus, Overdose, Sinus Tachycardia

This Agitation side effect was reported by a health professional from UNITED KINGDOM on Aug 30, 2010. A patient from UNITED KINGDOM , 40 years of age, was diagnosed with and was treated with Amitriptyline (ngx). Patient felt the following Amitriptyline side effects: abdominal discomfort, abdominal tenderness, agitation, brugada syndrome, intention tremor, moaning, nystagmus, overdose, sinus tachycardia. Amitriptyline (ngx) dosage: 800 Mg, Unk. The patient was hospitalized. These side effects may potentially be related to Amitriptyline (ngx).

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Amitriptyline Agitation Causes and Reviews


Caring for someone who has Alzheimer's disease (AD) can be stressful and overwhelming. It's important to take care of yourself. Ask for and accept help.

Talk to the doctor. Find out what treatments might help control symptoms or address behavior problems. Find a support group. Others who have "been there" may be able to help and will understand.

If there are times of day that the person is less confused or more cooperative, take advantage of that in daily routines. Consider using adult day care or respite services. These offer a break with the peace of mind that the patient is being taken care of. Begin to plan for the future. This may include

  • Getting financial and legal documents in order
  • Looking into assisted living or nursing homes
  • Finding out what your health insurance and Medicare will cover

NIH: National Institute on Aging


Amitriptyline Agitation Reviews

Fri, 09 Sep 2011

can Amitriptyline can cause thrombocytopenia ?

Wed, 16 Nov 2011

After having been on elavil for 9 years, mostly at 100mg/night, I spent the last 6 months weaning off. Shortly after stopping Amitriptyline I now have high blood pressure. Before stopping, and for years before starting, my usual pressure was 115/65, now have 150/68. Can this be a withdrawal symptom or has the drug been masking a heart problem all this time or did it cause damage that did not show up before stopping the drug?

Sun, 03 Jul 2011
Is a GG 40 with a Sandoz label made in a different laboratory than a GG 40 with a Geneva label? (I know they are both 10 mg of Amitriptyline.) Thank you. Appreciate reply as soon as possible.
Wed, 14 Dec 2011
im on Amitriptyline 25mg,i have my xmas party this weekend and wanted to drink alchol. i wonder is it a good idea
Thu, 10 Dec 2009
took Amitriptyline 200mg in a signle dose is it safe
Wed, 20 Jan 2010
Does Amtriptyline help tinnitus. I'm taking it at a low dose for jaw problems and fibromyalgia. the 25 mg dose seems to make my tinnitus worse but my pain better. I don't know what to do?
Wed, 20 Jan 2010
I'm taking Amitriptyline to relax my jaw and for pain and it seem to help tinnitus sonmetimes. Should I be taking noratfiptyline?
Mon, 07 Jun 2010
I HAVE JUST BEEN GIVEN AMITRIPTYLINE ,10MG FOR PAIN AND SLEEP BUT I HAVE BEEN READING ABOUT SIDE AFFECTS
Sun, 20 Jun 2010
Hey i took 500mg of Amitriptyline and overdosed and almost Died.. Dont take that much
Sun, 11 Jul 2010
been on amitrip 25mg at night for 8 nights now and have felt and look alot better. although i have diarrihea now and felt abit of nausea here and there . feel a tad tired throughout the day but i think for me the postives outweigh the negatives for now
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Amitriptyline Side Effects

Completed Suicide (98)
Toxicity To Various Agents (72)
Overdose (61)
Cardiac Arrest (57)
Somnolence (48)
Pain (47)
Convulsion (45)
Anxiety (44)
Headache (44)
Death (42)
Confusional State (40)
Vomiting (40)
Dizziness (39)
Intentional Overdose (39)
Dyspnoea (38)
Loss Of Consciousness (38)
Nausea (35)
Fatigue (35)
Coma (33)
Respiratory Arrest (33)
Depression (32)
Hypotension (31)
Agitation (31)
Hallucination (29)
Malaise (29)
Fall (28)
Cardio-respiratory Arrest (28)
Syncope (27)
Diarrhoea (26)
Insomnia (26)
Tremor (26)
Pyrexia (25)
Grand Mal Convulsion (25)
Delirium (24)
Asthenia (24)
Abdominal Pain (23)
Feeling Abnormal (23)
Suicide Attempt (23)
Dysarthria (22)
Depressed Level Of Consciousness (21)
Constipation (21)
Deep Vein Thrombosis (21)
Electrocardiogram Qt Prolonged (21)
Serotonin Syndrome (21)
Palpitations (21)
Weight Decreased (20)
Gait Disturbance (20)
Dry Mouth (19)
Metabolic Acidosis (19)
Rash (19)

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