Benadryl Off Label Use Side Effect Reports


The following Benadryl Off Label Use side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Off Label Use, can occur, and what you can do about them.

A side effect could appear soon after you start Benadryl or it might take time to develop.


Jaundice, Hepatic Enzyme Increased, Hepatic Pain, Renal Pain, Off Label Use

This Off Label Use side effect was reported by a consumer or non-health professional from US. A 55-year-old patient (weight:NA) experienced the following symptoms/conditions: nasal congestion,multiple allergies. The patient was prescribed Benadryl Allergy Dye-free (dosage: NA), which was started on Jan 11, 2014. Concurrently used drugs: NA. When starting to take Benadryl Allergy Dye-free the consumer reported the following symptoms:
  • Jaundice
  • Hepatic Enzyme Increased
  • Hepatic Pain
  • Renal Pain
  • Off Label Use
These side effects may potentially be related to Benadryl Allergy Dye-free.
Formication, Dysuria, Off Label Use, Pruritus

This Off Label Use Benadryl Allergy Kapgels side effect was reported by a consumer or non-health professional from CA on Dec 09, 2013. A Female , 65 years of age, weighting 138.0 lb, was diagnosed with and was treated with Benadryl Allergy Kapgels. The patient presented the following health conditions:
  • Formication
  • Dysuria
  • Off Label Use
  • Pruritus
. Benadryl Allergy Kapgels dosage: 1 Kapgel 2 Or 3 Times. Additional drugs used at the same time: NA.
Oxygen Saturation Decreased, Sensation Of Foreign Body, Off Label Use, Blood Pressure Decreased, Periorbital Oedema

This is a Benadryl side effect report of a 57-year-old female patient (weight:NA) from CA, suffering from the following symptoms/conditions: hypersensitivity,psoriatic arthropathy, who was treated with Benadryl (dosage:NA, start time: Feb 27, 2013), combined with:
  • Remicade
  • Epinephrine
, and developed a serious reaction and a Off Label Use side effect. The patient presented with:
  • Oxygen Saturation Decreased
  • Sensation Of Foreign Body
  • Off Label Use
  • Blood Pressure Decreased
  • Periorbital Oedema
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Benadryl treatment in female patients suffering from hypersensitivity,psoriatic arthropathy, resulting in Off Label Use.
Tremor, Off Label Use

A 50-year-old patient (weight: NA) from US with the following symptoms: restlessness,psychotic disorder,anxiety started Benadryl Allergy Ultratab treatment (dosage: 1/4 Tablet) on Oct 14, 2013. Soon after starting Benadryl Allergy Ultratab treatment, the consumer experienced several side effects, including:
  • Tremor
  • Off Label Use
. Concurrently used drugs:
  • Latuda
  • Zoloft
  • Zoloft
This finding indicates that some patients can be more vulnerable to developing Benadryl Allergy Ultratab side effects, such as Off Label Use.
Dyspnoea, Chest Pain, Swelling Face, Lip Swelling, Acne, Paraesthesia Oral, Off Label Use, Hypersensitivity, Chest Discomfort

A female patient from US was prescribed and started Benadryl Allergy Ultratab on Nov 20, 2013. Patient felt the following Benadryl side effects: dyspnoea, chest pain, swelling face, lip swelling, acne, paraesthesia oral, off label use, hypersensitivity, chest discomfort Additional patient health information: Female , 54 years of age, weighting 194.0 lb, The consumer reported the following symptoms: was diagnosed with and. Benadryl Allergy Ultratab dosage: NA. Concurrently used drugs: NA. The patient was hospitalized.
Application Site Reaction, Swelling Face, Eye Swelling, Off Label Use, Rash

This report suggests a potential Benadryl Allergy Ultratab Off Label Use side effect(s) that can have serious consequences. A 31-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): pruritus,anxiety and used Benadryl Allergy Ultratab (dosage: NA) starting 2012. Soon after starting Benadryl Allergy Ultratab the patient began experiencing various side effects, including:
  • Application Site Reaction
  • Swelling Face
  • Eye Swelling
  • Off Label Use
  • Rash
Drugs used concurrently:
  • Prozac
Although Benadryl Allergy Ultratab demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Off Label Use, may still occur.
Pneumonia, Arthritis, Gait Disturbance, Off Label Use

An adverse event was reported by a consumer or non-health professional on Sep 05, 2013 by a Female taking Benadryl (dosage: NA) . Location: US , 92 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Benadryl side effects: pneumonia, arthritis, gait disturbance, off label use. Additional medications/treatments: The patient was hospitalized.
Food Allergy, Local Swelling, Arthralgia, Off Label Use, Urticaria, Diarrhoea, Dyspepsia, Headache

This Off Label Use problem was reported by a consumer or non-health professional from CA. A 58-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): allergy to arthropod sting.On Aug 12, 2013 a consumer started treatment with Benadryl Rs Allergy 25mg Caplets (dosage: 1-2 Caplets). The following drugs/medications were being taken at the same time: NA. When commencing Benadryl Rs Allergy 25mg Caplets, the patient experienced the following unwanted symptoms /side effects:
  • Food Allergy
  • Local Swelling
  • Arthralgia
  • Off Label Use
  • Urticaria
  • Diarrhoea
  • Dyspepsia
  • Headache
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Off Label Use, may become evident only after a product is in use by the general population.
Hypersensitivity, Blister, Rash, Local Swelling, Off Label Use, Therapeutic Response Unexpected, Pruritus

This is a Benadryl side effect report of a 55-year-old patient (weight: NA) from US. The patient developed the following symptoms/conditions: rash,pruritus and was treated with Benadryl (dosage: A Pea Size Amount On Each Hand Twice) starting Jul 31, 2013. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Hypersensitivity
  • Blister
  • Rash
  • Local Swelling
  • Off Label Use
  • Therapeutic Response Unexpected
  • Pruritus
This opens a possibility that Benadryl could cause Off Label Use and that some patients may be more susceptible.
Anuria, Heart Rate Irregular, Off Label Use

This Off Label Use side effect was reported by a health professional from US on Jun 20, 2013. A patient from US , 69 years of age, was diagnosed with and was treated with Benadryl. Directly after treatment started, patient experienced the unwanted or unexpected Benadryl side effects: anuria, heart rate irregular, off label use. Benadryl dosage: NA. The patient was hospitalized. These side effects may potentially be related to Benadryl.
Anaphylactic Shock, Off Label Use

This Off Label Use side effect was reported by a consumer or non-health professional from US. A female patient (weight:NA) experienced the following symptoms/conditions: hypersensitivity,epilepsy,hypertension. The patient was prescribed Benadryl (dosage: 1/2 Tablet, 10 Minutes Apart 1/2 Tablet Again), which was started on NS. Concurrently used drugs:
  • Phenobarbital
  • Lipitor
When starting to take Benadryl the consumer reported the following symptoms:
  • Anaphylactic Shock
  • Off Label Use
These side effects may potentially be related to Benadryl.
Overdose, Off Label Use

This Off Label Use Benadryl side effect was reported by a consumer or non-health professional from US on May 28, 2013. A male , weighting 135.0 lb, was diagnosed with and was treated with Benadryl. The patient presented the following health conditions:
  • Overdose
  • Off Label Use
. Benadryl dosage: (20-30 Tabs/caps/gels) 15-30 Pill Each Day) Approximately 6-8 Months. Additional drugs used at the same time:
  • Marijuana
  • Cocaine
  • Maitake Mushroom
Visual Impairment, Off Label Use

This is a Benadryl Allergy Ultratab side effect report of a 89-year-old patient (weight:NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Benadryl Allergy Ultratab (dosage:2 Tablets At Night As Needed, start time: Oct 01, 2012), combined with:
  • Lotrel (5mg/20mg 1 Day, Since 3 Or 4 Years)
  • Toprol (3 Or 4 Years)
  • Tamsulosin (Since 1 Year)
  • Finasteride
, and developed a serious reaction and a Off Label Use side effect. The patient presented with:
  • Visual Impairment
  • Off Label Use
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Benadryl Allergy Ultratab treatment in patients suffering from NA, resulting in Off Label Use.
Hallucination, Abnormal Dreams, Insomnia, Overdose, Off Label Use

A 50-year-old female patient (weight: NA) from US with the following symptoms: NA started Benadryl Allergy treatment (dosage: NA) on Mar 06, 2013. Soon after starting Benadryl Allergy treatment, the consumer experienced several side effects, including:
  • Hallucination
  • Abnormal Dreams
  • Insomnia
  • Overdose
  • Off Label Use
. Concurrently used drugs:
  • Tylenol Pm
  • Ritalin (20mg, 3 Times A Day From Week.)
  • Ritalin (20mg, 3 Times A Day From Week.)
  • Ritalin (20mg, 3 Times A Day From Week.)
  • Bupropion (150mg For One And Half Weeks)
  • Abilify (5mg From Years)
  • Citalopram (20mg/day From Years)
  • Percocet (5mg/325mg 4 Times A Day From Years)
This finding indicates that some patients can be more vulnerable to developing Benadryl Allergy side effects, such as Off Label Use.
Overdose, Off Label Use, Therapeutic Response Unexpected

A patient from US was prescribed and started Benadryl Allergy on Apr 24, 2013. After Benadryl was administered, patient encountered several Benadryl side effects: overdose, off label use, therapeutic response unexpected Additional patient health information: male , 42 years of age, weighting 145.0 lb, The consumer reported the following symptoms: was diagnosed with and. Benadryl Allergy dosage: 6-12 Tablets Taken 2x. Concurrently used drugs: NA.
Myocardial Infarction, Discomfort, Off Label Use

This report suggests a potential Benadryl Allergy Ultratab Off Label Use side effect(s) that can have serious consequences. A 65-year-old patient from US (weight:NA) was diagnosed with the following health condition(s): NA and used Benadryl Allergy Ultratab (dosage: NA) starting 201012. Soon after starting Benadryl Allergy Ultratab the patient began experiencing various side effects, including:
  • Myocardial Infarction
  • Discomfort
  • Off Label Use
Drugs used concurrently:
  • Glipizide (3 Year)
  • Metformin (1 Year)
  • Lipitor (11 Year)
  • Losartan (1 Year)
  • Aspirin (7 Year)
  • Oxybutynin Chloride (9 Year)
  • Potassium Citrate (1 Year)
The patient was hospitalized. Although Benadryl Allergy Ultratab demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Off Label Use, may still occur.
Blood Pressure Increased, Off Label Use

An adverse event was reported by a consumer or non-health professional on Feb 05, 2013 by a Female taking Benadryl Allergy Ultratab (dosage: 1-2 Tablets Twice A Day.) . Location: US , weighting 120.0 lb, patient began experiencing various side effects, including: Patient felt the following Benadryl side effects: blood pressure increased, off label use. Additional medications/treatments:
Multiple prescriptions taken:
  • Fluocinonide
Hallucination, Visual Impairment, Psychomotor Hyperactivity, Off Label Use, Physical Product Label Issue

This Off Label Use problem was reported by a consumer or non-health professional from US. A 46-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Dec 03, 2012 a consumer started treatment with Benadryl Allergy Dye-free (dosage: 3 Pills In 25 Hours). The following drugs/medications were being taken at the same time: NA. When commencing Benadryl Allergy Dye-free, the patient experienced the following unwanted symptoms /side effects:
  • Hallucination
  • Visual Impairment
  • Psychomotor Hyperactivity
  • Off Label Use
  • Physical Product Label Issue
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Off Label Use, may become evident only after a product is in use by the general population.
Hallucination, Off Label Use

This is a Benadryl side effect report of a 46-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Benadryl (dosage: 3 Pills In 25 Hours) starting Jan 12, 2010. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Hallucination
  • Off Label Use
This opens a possibility that Benadryl could cause Off Label Use and that some female patients may be more susceptible.
Exposure During Pregnancy, Off Label Use

This Off Label Use side effect was reported by a consumer or non-health professional from US on Mar 04, 2013. A female patient from US , 19 years of age, was diagnosed with and was treated with Benadryl Allergy Dye-free. Patient felt the following Benadryl side effects: exposure during pregnancy, off label use. Benadryl Allergy Dye-free dosage: 2 Tablets Every 4 To 6 Hours. These side effects may potentially be related to Benadryl Allergy Dye-free.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Benadryl Off Label Use Causes and Reviews


Normally, your cells grow and die in a controlled way. Cancer cells keep growing without control. Chemotherapy is drug therapy for cancer. It works by killing the cancer cells, stopping them from spreading, or slowing their growth. However, it can also harm healthy cells, which causes side effects.

You may have a lot of side effects, some, or none at all. It depends on the type and amount of chemotherapy you get and how your body reacts. Some common side effects are fatigue, nausea, vomiting, pain, and hair loss. There are ways to prevent or control some side effects. Talk with your health care provider about how to manage them. Healthy cells usually recover after chemotherapy is over, so most side effects gradually go away.

Your treatment plan will depend on the cancer type, the chemotherapy drugs used, the treatment goal, and how your body responds. Chemotherapy may be given alone or with other treatments. You may get treatment every day, every week, or every month. You may have breaks between treatments so that your body has a chance to build new healthy cells. You might take the drugs by mouth, in a shot, as a cream, or intravenously (by IV).

NIH: National Cancer Institute


Benadryl Off Label Use Reviews

Sun, 04 Sep 2011

Can I die from taking this many. Is it physicly addicting? Sorry about my spelling.

Mon, 18 Jul 2011

I loved these strips. I have had allergic reactions to my own allergy shots. After waiting at the Dr.'s office for 15 minutes after my allergy shot, I leave to go shopping. Sometimes I can feel a little thickening in my throat, similar to when I've had a really bad reaction and had to go to the ER for help, or went back to the Dr.'s office for a shot of epinepherine. When I feel just a small reaction beginning, I have put one of the Benadryl Quick Dissolve Strips on my tongue. I get a pretty fast result and I can continue shopping rather than worrying about a worse reaction.

Now, when I went to buy more of this product, it isn't available at any local stores, or on line at safe sites. Each store tells me that people are coming in and wanting them and getting upset when they can't find them.

Why were these strips taken off the market?

Sun, 21 Mar 2010
Does taking too much Benadryl cause a person to fall asleep and not wake up?
Wed, 01 Sep 2010
It was given to me in a hospital through emergency room, for nauseau. Nusrse said that they use it for that as well. Is true and can it be usedat home for the same?
Thu, 24 Mar 2011
My son is allergic to children's Benadryl. It causes him to develop eye infections (conjunctivitus).
Sat, 30 Apr 2011
I've noticed that it when I am with my partner it makes me sensitive, but I am not able to be aroused. Is anyone else having the same issue. I've been taking it for alergies since I was a teenager. Its the only thing that has ever worked for me.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Benadryl Side Effects

Off Label Use (181)
Dyspnoea (162)
Nausea (141)
Hypersensitivity (139)
Urticaria (126)
Somnolence (119)
Vomiting (116)
Loss Of Consciousness (113)
Rash (109)
Pain (109)
Pruritus (108)
Headache (108)
Overdose (105)
Dizziness (102)
Product Quality Issue (102)
Insomnia (96)
Heart Rate Increased (86)
Hallucination (80)
Feeling Abnormal (79)
Condition Aggravated (78)
Anxiety (46)
Infusion Related Reaction (46)
Tremor (45)
Fatigue (45)
Diarrhoea (43)
Convulsion (42)
Erythema (38)
Malaise (38)
Pyrexia (38)
Asthenia (37)
Swelling Face (37)
Blood Pressure Increased (37)
Pharyngeal Oedema (35)
Throat Tightness (34)
Dehydration (32)
Chest Pain (31)
Swollen Tongue (30)
Pain In Extremity (30)
Cough (30)
Oedema Peripheral (29)
Hypoaesthesia (29)
Chest Discomfort (29)
Incorrect Dose Administered (28)
Abdominal Pain Upper (27)
Eye Swelling (27)
Flushing (26)
Fall (26)
Confusional State (25)
Lip Swelling (24)
Syncope (24)

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