Clonidine Fatigue Side Effect Reports


The following Clonidine Fatigue side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Fatigue, can occur, and what you can do about them.

A side effect could appear soon after you start Clonidine or it might take time to develop.


Blood Pressure Decreased, Glassy Eyes, Headache, Fatigue

This Fatigue side effect was reported by a consumer or non-health professional from US. A 6-year-old female patient (weight:NA) experienced the following symptoms/conditions: insomnia,off label use. The patient was prescribed Clonidine Hydrochloride (dosage: NA), which was started on 201305. Concurrently used drugs: NA. When starting to take Clonidine Hydrochloride the consumer reported the following symptoms:
  • Blood Pressure Decreased
  • Glassy Eyes
  • Headache
  • Fatigue
These side effects may potentially be related to Clonidine Hydrochloride.
Mental Status Changes, Toxicity To Various Agents, Hypotension, Sedation, Fatigue, Communication Disorder

This Fatigue Clonidine Hydrochloride side effect was reported by a pharmacist from US on May 09, 2013. A Female , 53 years of age, was treated with Clonidine Hydrochloride. The patient presented the following health conditions:
  • Mental Status Changes
  • Toxicity To Various Agents
  • Hypotension
  • Sedation
  • Fatigue
  • Communication Disorder
. Clonidine Hydrochloride dosage: 0.688 Mcg/hr: 20.38 Mcg/ml. Additional drugs used at the same time:
  • Baclofen ((1000 Mcg/hr))
The patient was hospitalized.
Dyspnoea, Myalgia, Asthenia, Fatigue, Gait Disturbance, Exercise Tolerance Decreased, Anhedonia

This is a Clonidine side effect report of a 76-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: hypertension, who was treated with Clonidine (dosage:NA, start time: Apr 24, 2012), combined with: NA., and developed a serious reaction and a Fatigue side effect. The patient presented with:
  • Dyspnoea
  • Myalgia
  • Asthenia
  • Fatigue
  • Gait Disturbance
  • Exercise Tolerance Decreased
  • Anhedonia
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Clonidine treatment in female patients suffering from hypertension, resulting in Fatigue.
Toxicity To Various Agents, Fatigue, Pain In Jaw, Feeling Hot, Blood Pressure Increased

A 56-year-old female patient (weight: NA) from US with the following symptoms: blood pressure high started Clonidine Hcl treatment (dosage: NA) on Aug 26, 2012. Soon after starting Clonidine Hcl treatment, the consumer experienced several side effects, including:
  • Toxicity To Various Agents
  • Fatigue
  • Pain In Jaw
  • Feeling Hot
  • Blood Pressure Increased
. Concurrently used drugs:
  • Lisinopril
This finding indicates that some patients can be more vulnerable to developing Clonidine Hcl side effects, such as Fatigue.
Somnolence, Dry Mouth, Fatigue, Dizziness

A female patient from US was prescribed and started Clonidine Hydrochloride on Oct 01, 2012. Patient felt the following Clonidine side effects: somnolence, dry mouth, fatigue, dizziness Additional patient health information: Female , weighting 152.1 lb, The consumer reported the following symptoms: was diagnosed with and. Clonidine Hydrochloride dosage: NA. Concurrently used drugs:
  • Furosemide
  • Lisinopril
  • Aspirin
  • Metoprolol
  • Doxazosin
Vomiting, Fatigue, Dizziness, Chest Discomfort, Coronary Artery Stenosis, Coronary Artery Occlusion, Coronary Artery Dissection, Haemorrhage Coronary Artery

This report suggests a potential Clonidine Fatigue side effect(s) that can have serious consequences. A 44-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): hypertension and used Clonidine (dosage: 0.3 Mg 1x/week, [patch] Transdermal)) starting NS. Soon after starting Clonidine the patient began experiencing various side effects, including:
  • Vomiting
  • Fatigue
  • Dizziness
  • Chest Discomfort
  • Coronary Artery Stenosis
  • Coronary Artery Occlusion
  • Coronary Artery Dissection
  • Haemorrhage Coronary Artery
Drugs used concurrently:
  • Hydrochlorothiazide
  • Simvastatin
The patient was hospitalized. Although Clonidine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Fatigue, may still occur.
Oedema, Constipation, Dry Mouth, Breath Odour, Fatigue, Sleep Disorder

An adverse event was reported by a consumer or non-health professional on Aug 28, 2012 by a Female taking Clonidine Hcl (dosage: 2 Tab 2x^s Per Day) was diagnosed with and. Location: US , 61 years of age, weighting 262.0 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Clonidine side effects: oedema, constipation, dry mouth, breath odour, fatigue, sleep disorder. Additional medications/treatments:
Arrhythmia, Somnolence, Product Substitution Issue, Fatigue, Chest Pain, Feeling Abnormal

This Fatigue problem was reported by a consumer or non-health professional from UNITED STATES. A 79-year-old patient (weight: NA) was diagnosed with the following medical condition(s): hypertension.On May 13, 2012 a consumer started treatment with Clonidine (dosage: 0.1 Weekly Shoulder). The following drugs/medications were being taken at the same time:
  • Travantan
  • Xanax
  • Hydrochlorothiazide
  • Lisinipril
  • Betoptic S
  • Aspirin
  • Amlodipine
  • Flecanaide
When commencing Clonidine, the patient experienced the following unwanted symptoms /side effects:
  • Arrhythmia
  • Somnolence
  • Product Substitution Issue
  • Fatigue
  • Chest Pain
  • Feeling Abnormal
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Thrombophlebitis Superficial, Pain, Anhedonia, Deep Vein Thrombosis, Anxiety, Fatigue, Asthenia, Injury

This is a Clonidine side effect report of a 26-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Clonidine (dosage: NA) starting Jan 01, 2007. Concurrently used drugs:
  • Yaz (Unk)
  • Lexapro
Soon after that, the consumer experienced the following of symptoms:
  • Thrombophlebitis Superficial
  • Pain
  • Anhedonia
  • Deep Vein Thrombosis
  • Anxiety
  • Fatigue
  • Asthenia
  • Injury
The patient was hospitalized. This opens a possibility that Clonidine could cause Fatigue and that some female patients may be more susceptible.
Diabetes Mellitus, Application Site Discomfort, Fatigue, Pain, Hepatitis, Nausea, Decreased Appetite, Pain In Extremity

This Fatigue side effect was reported by a consumer or non-health professional from BRAZIL on Mar 01, 2012. A female patient from BRAZIL , 59 years of age, weighting 132.3 lb, was diagnosed with and was treated with Clonidine Hydrochloride. Directly after treatment started, patient experienced the unwanted or unexpected Clonidine side effects: diabetes mellitus, application site discomfort, fatigue, pain, hepatitis, nausea, decreased appetite, pain in extremity. Clonidine Hydrochloride dosage: 200 Mg, 2x/day.
Associated medications used:
  • Enbrel (50 Mg, Weekly)
  • Enbrel (Unk, Weekly)
  • Glyburide (5 Mg, 1x/day)
  • Atenolol (100 Mg, 2x/day)
  • Omeprazole (20 Mg, 1x/day)
  • Acetaminophen (100 Mg, As Needed)
  • Metformin (850 Mg, 3x/day)
  • Aspirin (200 Mg, 2 Tablets Of 100 Mg, Alternate Day)
These side effects may potentially be related to Clonidine Hydrochloride.
Hypertension, Chromaturia, Fatigue, Amnesia, Limb Discomfort, Blood Pressure Increased

This Fatigue side effect was reported by a consumer or non-health professional from UNITED STATES. A 75-year-old patient (weight:NA) experienced the following symptoms/conditions: hypertension. The patient was prescribed Clonidine Hcl (dosage: .1mg Twice Per Day), which was started on Sep 25, 2010. Concurrently used drugs:
  • Flomax (.4mg Twice Per Day)
  • Omeprazole (20mgd Per Day)
  • Votrient (200mg Twice Per Day)
  • Synthroid (125mcg Per Day)
  • Aspirin (81mgd Per Day)
  • Votrient (400mg Twice Per Day)
  • Zocor (40mgd Per Day)
  • Cardizem (180mgd Per Day)
When starting to take Clonidine Hcl the consumer reported the following symptoms:
  • Hypertension
  • Chromaturia
  • Fatigue
  • Amnesia
  • Limb Discomfort
  • Blood Pressure Increased
These side effects may potentially be related to Clonidine Hcl.
Ileus, Constipation, Fatigue

This Fatigue Clonidine Tablets 0.3 Mg side effect was reported by a consumer or non-health professional from US on Oct 01, 2012. A male , 68 years of age, weighting 200.2 lb, was diagnosed with and was treated with Clonidine Tablets 0.3 Mg. The patient presented the following health conditions:
  • Ileus
  • Constipation
  • Fatigue
. Clonidine Tablets 0.3 Mg dosage: NA. Additional drugs used at the same time:
  • Diltiazem
  • Terazosin
  • Lisinopril
  • Niacin
Myocardial Infarction, Dyspnoea, Swelling, Fatigue

This is a Clonidine side effect report of a 60-year-old female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Clonidine (dosage:NA, start time: Apr 20, 2004), combined with:
  • Xenical
  • Glyburide
  • Avandamet
  • Pravachol
  • Avandia
  • Adalat
, and developed a serious reaction and a Fatigue side effect. The patient presented with:
  • Myocardial Infarction
  • Dyspnoea
  • Swelling
  • Fatigue
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Clonidine treatment in female patients suffering from NA, resulting in Fatigue.
Fatigue, Blood Pressure Decreased

A 60-year-old female patient (weight: NA) from UNITED STATES with the following symptoms: NA started Clonidine Hcl treatment (dosage: NA) on NS. Soon after starting Clonidine Hcl treatment, the consumer experienced several side effects, including:
  • Fatigue
  • Blood Pressure Decreased
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Clonidine Hcl side effects, such as Fatigue.
Fatigue, Ileus, Constipation

A patient from UNITED STATES was prescribed and started Clonidine on Jun 09, 2011. After Clonidine was administered, patient encountered several Clonidine side effects: fatigue, ileus, constipation Additional patient health information: male , weighting 200.2 lb, The consumer reported the following symptoms: was diagnosed with and. Clonidine dosage: NA. Concurrently used drugs:
  • Diltiazem
  • Lisinopril
  • Terazosin Hcl
  • Niacin
Presyncope, Arrhythmia, Fatigue

This report suggests a potential Clonidine Fatigue side effect(s) that can have serious consequences. A 88-year-old female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): hypertension and used Clonidine (dosage: Changed Qw) starting NS. Soon after starting Clonidine the patient began experiencing various side effects, including:
  • Presyncope
  • Arrhythmia
  • Fatigue
Drugs used concurrently:
  • Chlorthalidone (25mg)
  • Hydralazine Hcl
  • Diltiazem (180mg Daily)
  • Lisinopril (40mg)
  • Metoprolol
The patient was hospitalized. Although Clonidine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Fatigue, may still occur.
Fatigue, Plicated Tongue, Nausea, Alopecia

An adverse event was reported by a consumer or non-health professional on Aug 03, 2011 by a male taking Clonidine (dosage: NA) . Location: UNITED STATES , 54 years of age, patient began experiencing various side effects, including: Patient felt the following Clonidine side effects: fatigue, plicated tongue, nausea, alopecia. Additional medications/treatments:
Multiple prescriptions taken:
  • Nexavar (200 Mg, Qd)
  • Trazodone Hcl
  • Sorbitol [sorbitol]
  • Lantus
  • Promethazine (Unk)
  • Lorazepam (Unk)
  • Lisinopril
Renal Failure, Ketoacidosis, Diabetic Nephropathy, Nausea, Renal Failure Acute, Anaemia, Fatigue, Vomiting

This Fatigue problem was reported by a health professional from UNITED STATES. A 27-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Jan 01, 2005 a consumer started treatment with Clonidine (dosage: NA). The following drugs/medications were being taken at the same time:
  • Protonix
  • Yasmin
  • Novolog (Sliding Scale)
  • Reglan
  • Zyvox
  • Vancomycin
  • Humulin R
  • Lantus (18 Units)
When commencing Clonidine, the patient experienced the following unwanted symptoms /side effects:
  • Renal Failure
  • Ketoacidosis
  • Diabetic Nephropathy
  • Nausea
  • Renal Failure Acute
  • Anaemia
  • Fatigue
  • Vomiting
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Fatigue, Blood Pressure Increased, Product Adhesion Issue, Somnolence, Dry Mouth

This is a Clonidine side effect report of a 71-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: hypertension and was treated with Clonidine (dosage: (0.1 Mg Qd, Via 1/weely Patch Transdermal)) starting Dec 06, 2010. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Fatigue
  • Blood Pressure Increased
  • Product Adhesion Issue
  • Somnolence
  • Dry Mouth
This opens a possibility that Clonidine could cause Fatigue and that some female patients may be more susceptible.
Anaemia, Proteinuria, Constipation, Diabetic Nephropathy, Fatigue, Renal Failure, Ketoacidosis, Nausea, Vomiting

This Fatigue side effect was reported by a health professional from UNITED STATES on Dec 06, 2010. A female patient from UNITED STATES , weighting 136.7 lb, was treated with Clonidine. Patient felt the following Clonidine side effects: anaemia, proteinuria, constipation, diabetic nephropathy, fatigue, renal failure, ketoacidosis, nausea, vomiting. Clonidine dosage: NA.
Multiple prescriptions taken:
  • Zyvox
  • Ibuprofen (Used Very Rarely)
  • Yasmin
  • Humulin N
  • Prednisone
  • Benicar (40 Mg (daily Dose), ,)
  • Lasix
  • Reglan
The patient was hospitalized. These side effects may potentially be related to Clonidine.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Clonidine Fatigue Causes and Reviews


Everyone feels tired now and then. Sometimes you may just want to stay in bed. But, after a good night's sleep, most people feel refreshed and ready to face a new day. If you continue to feel tired for weeks, it's time to see your doctor. He or she may be able to help you find out what's causing your Fatigue and recommend ways to relieve it.

Fatigue itself is not a disease. Medical problems, treatments, and personal habits can add to Fatigue. These include

  • Taking certain medicines, such as antidepressants, antihistamines, and medicines for nausea and pain
  • Having medical treatments, like chemotherapy and radiation
  • Recovering from major surgery
  • Anxiety, stress, or depression
  • Staying up too late
  • Drinking too much alcohol or too many caffeinated drinks
  • Pregnancy

One disorder that causes extreme Fatigue is chronic Fatigue syndrome (CFS). This Fatigue is not the kind of tired feeling that goes away after you rest. Instead, it lasts a long time and limits your ability to do ordinary daily activities.

NIH: National Institute on Aging


Clonidine Fatigue Reviews

Mon, 07 May 2012

prescribed Clonidine 2 months ago for hot flushes due to the menopause. I am taking 25mcg twice a day as I cnnot tolerate the advised dose of 50mcg twice a day, but this lower dose has stopped the flushes. Infortunately I have been perpetually cold and have become really irritable. Is this a drug reaction or more symptoms of the menopause?

Sun, 22 May 2011

i am feeling drowsy,weak, and my heart is racing. is that suppose to happen?

Wed, 28 Dec 2011

I take only a portion of a 0.1 mg Clonidine once a day. Since I have been taking this medicine, the have been times that my skin feels that needles are sticking in it---this is all over my body. Has anyone else had this happen? I don't know for sure this is from this medicine, but it started shortly after I started taking it.

Mon, 01 Jun 2009
I take 0*1 mg Clonidine for high BP and have the sensation that my esophagus or chest muscles are spasming. Also my heart rate is accelerated. Are these expected side effects of this medication.
Sun, 15 Nov 2009
I just started on Clonidine for excessive sweating of the scalp and face, but also for insomnia. I had to take .3 mg to get sleepy. I woke up this morning with several canker like sores on the inside of my lips. Anyone else had this happen? I also use a cpap machine and am on other medications.
Mon, 16 Nov 2009
rashes, itch, soreness, pain
Wed, 17 Mar 2010
i started with taking 1 at bedtime .1mg then bp went up then went to .1 4 per day didn't last then tried Transdermal system this didn't stick to my skin result no medicine delivered i went thru withdraw ?
Fri, 30 Jul 2010
head, ears, throat, too tired, hate to take it.....Dr. said it is a nasty pill but still prescribed it. also, constipation/ loose stools. stomach discomfort....leg / foot spasms at night
Fri, 30 Jul 2010
I find this medication terrible. I dont know about anyone else but I have found that my body has become addictived to this drug. I have only been on this drug since June 18, 2010. I am on the patch 2mg plus one 1 mg tablet 2x per day (total of 4mg) If I do not take this mediction exactly within one hour before it wears of I start to go trough withdrawls. My head get tight my body starts to shake and I start to have a feeling of doom.When this first happen to me I went to the Emergency Room because I did not know what was happening to me. They discharged me because My blood pressure was not that high. Lucky for me My doctor's office was accross the street. I went to see him. He told me that this was one of the side effects of the drug. I told him that I could not live this way. He said this feeling would eventually go away but I had to stay on this drug because when you dont take this drug your blood pressure could spike very high. I was devastated to find that I was taking a drug that could potentially kill me if not taken timely.I have told the doctor that he had to find a way to get me off this medication. I can not function on this med. My vision is getting worse, I have difficulty concentrating, I am extremely aggitated and nervous all the time not to mention that I am so tired I can barely walk a block. I recently spoke with two different doctors who told me that I should not have been put on this med alone. I am so frustrated I dont know what to do. No one seem to be able to help me. Am I doomed to be this sick the reat of my life or is there something that can be done. Sincerely, Hopeless
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Clonidine Side Effects

Blood Pressure Increased (136)
Completed Suicide (121)
Hypotension (117)
Hypertension (95)
Product Adhesion Issue (72)
Headache (68)
Product Substitution Issue (64)
Dizziness (62)
Dyspnoea (55)
Product Quality Issue (54)
Poisoning (53)
Bradycardia (52)
Death (49)
Cardiac Arrest (47)
Nausea (45)
Somnolence (43)
Dry Mouth (42)
Fatigue (41)
Anxiety (40)
Asthenia (39)
Overdose (38)
Pain (35)
Agitation (34)
Feeling Abnormal (32)
Suicide Attempt (31)
Lethargy (31)
Depression (30)
Heart Rate Increased (30)
Sinus Bradycardia (30)
Loss Of Consciousness (29)
Hypertensive Crisis (29)
Vomiting (28)
Respiratory Arrest (28)
Chest Pain (26)
Blood Pressure Decreased (25)
Syncope (25)
Convulsion (24)
Cardio-respiratory Arrest (24)
Rash (23)
Application Site Rash (23)
Blood Pressure Inadequately Controlled (22)
Insomnia (22)
Cerebrovascular Accident (22)
Hyperhidrosis (21)
Accidental Overdose (20)
Tachycardia (20)
Application Site Pruritus (20)
Hypersensitivity (19)
Tremor (19)
Sedation (19)

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