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COZAAR and SPIRONOLACTONE

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectCOZAARSPIRONOLACTONE
DYSPNOEA2.8% 3.7%
NAUSEA3% 2.9%
FATIGUE2.9% 2.7%
DRUG INEFFECTIVE2.8% 1.7%
DIZZINESS2.7% 2.2%
DIARRHOEA2.5% 2.4%
HEADACHE2.1% 1.8%
PAIN2.1% 1.7%
ASTHENIA2% 2%
HYPOTENSION1.2% 1.9%
FALL1.7% 1.8%
VOMITING1.7% 1.8%
HYPERTENSION1.8% 0.9%
HYPERKALAEMIA0.5% 1.8%
MALAISE1.6% 1.6%
PNEUMONIA1.4% 1.6%
OEDEMA PERIPHERAL1.3% 1.6%
ANAEMIA1.3% 1.6%
CARDIAC FAILURE CONGESTIVE1.3% 1.6%
RENAL FAILURE ACUTE0.9% 1.6%
COUGH1.5% 1.2%
PAIN IN EXTREMITY1.5% 1.1%
ARTHRALGIA1.5% 1%
MYOCARDIAL INFARCTION1.5% 0.9%
WEIGHT DECREASED1.4% 1.2%
CHEST PAIN1.4% 1.1%
DEATH1% 1.4%
BLOOD PRESSURE INCREASED1.4% 0.5%
CARDIAC FAILURE0.5% 1.4%
RENAL FAILURE1.1% 1.3%
DEHYDRATION0.9% 1.3%
RASH1.3% 0.9%
PRURITUS1.3% 0.9%
BLOOD GLUCOSE INCREASED1.3% 0.8%
PYREXIA1.1% 1.2%
BACK PAIN1.2% 0.9%
DRUG INTERACTION0.9% 1.2%
INSOMNIA1.2% 0.8%
ANXIETY1.1% 1%
ATRIAL FIBRILLATION0.9% 1.1%
CONDITION AGGRAVATED0.8% 1.1%
GASTROINTESTINAL HAEMORRHAGE0.7% 1.1%
CEREBROVASCULAR ACCIDENT1.1% 0.6%
ABDOMINAL PAIN0.9% 1%
WEIGHT INCREASED0.9% 1%
DECREASED APPETITE0.9% 1%
CONFUSIONAL STATE0.8% 1%
CONSTIPATION1% 0.8%
DEPRESSION1% 0.8%
FEELING ABNORMAL1% 0.7%
MYALGIA1% 0.6%
ACUTE KIDNEY INJURY0% 1%
OFF LABEL USE0.7% 0.9%
GAIT DISTURBANCE0.9% 0.7%
MUSCLE SPASMS0.9% 0.7%
ABDOMINAL PAIN UPPER0.9% 0.7%
BLOOD CREATININE INCREASED0.6% 0.9%
ASCITES0% 0.9%
URINARY TRACT INFECTION0.8% 0.8%
SOMNOLENCE0.8% 0.7%
HAEMOGLOBIN DECREASED0.6% 0.8%
RENAL IMPAIRMENT0.5% 0.8%
FLUID RETENTION0% 0.8%
INTERNATIONAL NORMALISED RATIO INCREASED0% 0.8%
HYPONATRAEMIA0% 0.8%
SYNCOPE0.6% 0.7%
PALPITATIONS0.7% 0.6%
FLUSHING0.7% 0.5%
HYPOAESTHESIA0.7% 0.5%
TREMOR0.7% 0.5%
SEPSIS0.4% 0.7%
VISION BLURRED0.7% 0%
DRUG HYPERSENSITIVITY0.7% 0%
PARAESTHESIA0.7% 0%
OEDEMA0% 0.7%
LOSS OF CONSCIOUSNESS0.6% 0.6%
DRUG DOSE OMISSION0.6% 0.5%
ABDOMINAL DISTENSION0.5% 0.6%
BLOOD PRESSURE DECREASED0.5% 0.6%
MUSCULAR WEAKNESS0.6% 0.5%
ERYTHEMA0.6% 0.5%
CARDIAC ARREST0.4% 0.6%
DIABETES MELLITUS0.6% 0.4%
GENERAL PHYSICAL HEALTH DETERIORATION0% 0.6%
CORONARY ARTERY DISEASE0.6% 0%
EPISTAXIS0% 0.6%
PERIPHERAL SWELLING0% 0.6%
BRADYCARDIA0% 0.6%
HYPERSENSITIVITY0.6% 0%
NASOPHARYNGITIS0.6% 0%
RESPIRATORY FAILURE0% 0.6%
HYPERHIDROSIS0.6% 0%
PLEURAL EFFUSION0% 0.6%
ALOPECIA0.5% 0.5%
BRONCHITIS0.5% 0.5%
CONTUSION0.4% 0.5%
HEPATIC FAILURE0% 0.5%
ALANINE AMINOTRANSFERASE INCREASED0% 0.5%
HYPOKALAEMIA0% 0.5%
PLATELET COUNT DECREASED0% 0.5%
INJURY0% 0.5%
PULMONARY HYPERTENSION0% 0.5%
PULMONARY EMBOLISM0% 0.5%
THROMBOCYTOPENIA0% 0.5%
CHRONIC OBSTRUCTIVE PULMONARY DISEASE0% 0.5%
PULMONARY OEDEMA0% 0.5%
BLOOD CHOLESTEROL INCREASED0.5% 0%
INJECTION SITE PAIN0.5% 0%
HEART RATE INCREASED0.5% 0%
ABDOMINAL DISCOMFORT0.5% 0%
CHEST DISCOMFORT0.5% 0%
DYSPEPSIA0.5% 0%
GASTROOESOPHAGEAL REFLUX DISEASE0.5% 0%
DYSPHAGIA0.5% 0%
DRY MOUTH0.5% 0%
SINUSITIS0.5% 0%
PRODUCT QUALITY ISSUE0.5% 0%
ASTHMA0.5% 0%
CHILLS0.5% 0%
CARDIAC DISORDER0.5% 0%
HYPOGLYCAEMIA0.5% 0%
HEPATIC CIRRHOSIS0% 0.4%
JOINT SWELLING0.4% 0%

New treatments are found every day. View current COZAAR research studies and SPIRONOLACTONE clinical trials


Top 5 COZAAR Reported Side Effects

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Top 5 SPIRONOLACTONE Reported Side Effects

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Patient Forum

Recent Comments and Reports

Am a 76 year-old hypertensive with CKD; was given 'Cozaar' and 6 months into therapy developed excessive swelling of ankles/feet. Asked for GFR., and the result was 38, when I had been at a level of 54 for the previous 5 years. Ceased 'Cozaar' 4 mont

Back pain, horrible itching, confusion, insomnia, headache, did I mention back pain? It did bring down my blood pressure, No way I would even THINK of taking again. All this happened in 2 weeks! One of the WORST experiences of my life.

Do I need to register or hold membership to ask questions and get answers?

Got fluid ,back pain &headachs relly bad .dont want any more of this

Hello, Sorry to hear about you problems with this drug! YOU HAVE TO CHANGE YOUR MEDICIN ASAP!!! Ther is a lot of blood pressure medicin; hard to improv (I have done several times, use right now Coozar 50mg since 3 year, have to change asap becaus

How long do you have to keep taking it?

I am a female patient from NY, age 33. I am being treated for Hashimoto Thyroiditis with Synthroid and Cytomel. I was concerned that after 11 years since my diagnosis, my hair is still falling out at an alarming rate. My doctor noticed that my testos

I don't want to say my side-effects are from Cozaar alone, but I do feel a little different. I also take Metoprolol for my high blood. Anyway, I can't walk normally anymore. I'm a Carpenter by trade and that makes it 10 's harder. I walk with a limp.

I have been in a very debilitating state as far as sever muscle pain and injuries to the point i could barely walk i discontiued cozaar and am slowy getting back i believe with all my being it was due to cozaar and had to try to convince my dr. over

I have taken Cozaar for 8 years, never had a problem. My dose was 100 mg at night and 50 mg in morning. Suddenly out of the blue my blood pressure spiked to 185/135 and my heart went into a continuous fibrilation that lasted 2 hou

I started taking Spiro A YEAR AGO for my adult acne that no other medications have successfully treated. Spiro dried up all my oil and cleared my skin in 2 months! I have also gotten bigger breasts (but no complaints,here). The only downsides a

I was on Spironolactone (12.5 daily) . Hindsight, almost immediately I began suffering from ED. Mixed symptoms thought at the time from Diabetes T2 . Was also on Ace Inhibitors, Digoxin, Ibuprofenm Furosemide. After 18 months suddenly developed M

Am a 76 year-old hypertensive with CKD; was given 'Cozaar' and 6 months into therapy developed excessive swelling of ankles/feet. Asked for GFR., and the result was 38, when I had been at a level of 54 for the previous 5 years. Ceased 'Cozaar' 4 mont

Higher morning readings than Cozaar 50mg than Losartan 50mg

I don't want to say my side-effects are from Cozaar alone, but I do feel a little different. I also take Metoprolol for my high blood. Anyway, I can't walk normally anymore. I'm a Carpenter by trade and that makes it 10 's harder. I walk with a limp.

I have been in a very debilitating state as far as sever muscle pain and injuries to the point i could barely walk i discontiued cozaar and am slowy getting back i believe with all my being it was due to cozaar and had to try to convince my dr. over

I have taken Cozaar for 8 years, never had a problem. My dose was 100 mg at night and 50 mg in morning. Suddenly out of the blue my blood pressure spiked to 185/135 and my heart went into a continuous fibrilation that lasted 2 hou

Ishave been on the same two med' and i too have had trouble with my legs. It is as you say, they are tired and I also get a burning feeling. I am taking 100 mg of cozaar and I am going to have the doc take me off.

My husband was on Cozaar and then on Hyzaar. During this time he developed and very bad cough and he was diagnosed with Pulmonary Fibrosis. He died recently with this horrible disease. Could these medications have been the beginning of his problem