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Codeine and Methotrexate

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectCodeineMethotrexate
DRUG INEFFECTIVE3% 7.1%
ARTHRALGIA1.9% 3.5%
RHEUMATOID ARTHRITIS0.8% 3.3%
NAUSEA3.2% 2.7%
DRUG HYPERSENSITIVITY3% 1.2%
PAIN2.8% 2.9%
FATIGUE2.9% 2.5%
INJECTION SITE PAIN0% 2.8%
DYSPNOEA2.4% 1.5%
HEADACHE2.3% 2.3%
DIARRHOEA2.2% 1.7%
VOMITING2.2% 1.6%
PAIN IN EXTREMITY1.5% 2%
MALAISE1.9% 1.6%
PYREXIA1.2% 1.9%
DIZZINESS1.9% 1.1%
PNEUMONIA1.5% 1.7%
FALL1.7% 1.2%
ASTHENIA1.6% 1.1%
JOINT SWELLING0.7% 1.6%
DEATH1.6% 0.5%
TOXICITY TO VARIOUS AGENTS1.6% 0.4%
RASH1.4% 1.3%
WEIGHT DECREASED1.4% 1%
COUGH1.3% 1.3%
CONDITION AGGRAVATED1.2% 1.3%
BACK PAIN1.3% 1%
DEPRESSION1.3% 0.6%
COMPLETED SUICIDE1.3% 0%
INJECTION SITE ERYTHEMA0% 1.3%
ABDOMINAL PAIN1.2% 0.9%
NASOPHARYNGITIS0.8% 1.2%
ANXIETY1.2% 0.5%
INSOMNIA1.2% 0.5%
CONSTIPATION1.2% 0%
SOMNOLENCE1.2% 0%
OFF LABEL USE1.1% 1%
HYPERTENSION1.1% 0.8%
PRURITUS1.1% 0.8%
GAIT DISTURBANCE1% 0.9%
CHEST PAIN1% 0.7%
INFECTION0.5% 1%
SINUSITIS0.5% 1%
DRUG INTOLERANCE0% 1%
PSORIASIS0% 1%
PERIPHERAL SWELLING0.8% 0.9%
URINARY TRACT INFECTION0.8% 0.9%
WEIGHT INCREASED0.9% 0.7%
DRUG DOSE OMISSION0.9% 0.7%
ABDOMINAL PAIN UPPER0.9% 0.6%
FEELING ABNORMAL0.9% 0.5%
DECREASED APPETITE0.9% 0.5%
ALOPECIA0.5% 0.9%
DRUG INTERACTION0.9% 0.5%
MUSCULOSKELETAL STIFFNESS0.4% 0.9%
SEPSIS0% 0.9%
ANAEMIA0.8% 0.7%
ABDOMINAL DISCOMFORT0.8% 0.7%
OEDEMA PERIPHERAL0.8% 0.6%
HYPOTENSION0.8% 0.5%
BLOOD PRESSURE INCREASED0.8% 0.5%
ARTHRITIS0% 0.8%
INJECTION SITE PRURITUS0% 0.8%
DRUG EFFECT INCOMPLETE0% 0.8%
DRUG EFFECT DECREASED0% 0.8%
TREATMENT FAILURE0% 0.8%
OVERDOSE0.8% 0%
CONFUSIONAL STATE0.8% 0%
HYPOAESTHESIA0.7% 0.6%
HYPERSENSITIVITY0.7% 0.6%
BRONCHITIS0.5% 0.7%
PARAESTHESIA0.7% 0.5%
ERYTHEMA0.5% 0.7%
MYOCARDIAL INFARCTION0.7% 0.4%
MUSCLE SPASMS0.7% 0.4%
PANCYTOPENIA0% 0.7%
PRODUCT USE ISSUE0.7% 0%
DEHYDRATION0.7% 0%
INJECTION SITE REACTION0% 0.7%
HAEMOGLOBIN DECREASED0.7% 0%
INJECTION SITE SWELLING0% 0.7%
INFLUENZA0.5% 0.6%
SWELLING0.4% 0.6%
OSTEOARTHRITIS0.4% 0.6%
MUSCULOSKELETAL PAIN0.4% 0.6%
OROPHARYNGEAL PAIN0.4% 0.6%
MYALGIA0.6% 0.4%
HERPES ZOSTER0% 0.6%
HEPATIC ENZYME INCREASED0% 0.6%
INJECTION SITE BRUISING0% 0.6%
NEUTROPENIA0% 0.6%
FEBRILE NEUTROPENIA0% 0.6%
MIGRAINE0.6% 0%
ARTHROPATHY0% 0.6%
TREMOR0.6% 0%
CEREBROVASCULAR ACCIDENT0.6% 0%
CONTUSION0.5% 0.4%
MUSCULAR WEAKNESS0.5% 0.4%
URTICARIA0.5% 0.4%
INFUSION RELATED REACTION0.4% 0.5%
RENAL FAILURE0.5% 0.4%
THROMBOCYTOPENIA0% 0.5%
INJECTION SITE HAEMORRHAGE0% 0.5%
STOMATITIS0% 0.5%
MOBILITY DECREASED0% 0.5%
INCORRECT DOSE ADMINISTERED0% 0.5%
HYPERHIDROSIS0.5% 0%
DYSPEPSIA0.5% 0%
MEMORY IMPAIRMENT0.5% 0%
LOSS OF CONSCIOUSNESS0.5% 0%
SYNCOPE0.5% 0%
DRUG ABUSE0.5% 0%
ATRIAL FIBRILLATION0.5% 0%
VISUAL IMPAIRMENT0.5% 0%
DEEP VEIN THROMBOSIS0.5% 0%
GASTROINTESTINAL HAEMORRHAGE0.5% 0%
DYSPHAGIA0.5% 0%
ABDOMINAL DISTENSION0.5% 0%
VISION BLURRED0.5% 0%
MUCOSAL INFLAMMATION0% 0.4%
SYNOVITIS0% 0.4%
CHILLS0% 0.4%
INFLAMMATION0% 0.4%
CELLULITIS0% 0.4%
GASTROOESOPHAGEAL REFLUX DISEASE0.4% 0%
HEART RATE INCREASED0.4% 0%
PALPITATIONS0.4% 0%
INJURY0.4% 0%
CHEST DISCOMFORT0.4% 0%

New treatments are found every day. View current Codeine research studies and Methotrexate clinical trials


Top 5 Codeine Reported Side Effects

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Top 5 Methotrexate Reported Side Effects

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Patient Forum

Recent Comments and Reports

<span style='color: #808080;'>i took dihydracodine and got great painless hours after a serious motorcycle accident , i wont go into details and bore you ,<span style='text-decoration: underline;'>i am now on methadone for life,<strong

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spo

I feel quite spaced out i was given it today after an painfull extraction each tablet is 30mg and i have taken two

I have been on methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is

I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause diss

I only took it for 21 days but in that time, it put me into a full panic attack that lasted almost 8 days after I went off the medication. I had mental confusion, could not speak properly (I knew what I wanted to say but the words would not come out

I was diagnosed with Rheumatoid Arthritis about 4 years ago when I was 13 or 14, they looked at me and said I had it, they didn't do any blood tests and when they did, nothing showed. But they started me on about 5 mg of Methotrexate, Prednisone, and

Iwas given dihydrocodeine after being in hospital with tonsillitis that progressed into glandular fever. After my first dose of Dihydrocodeine i felt spaced out and was staring at the ceiling laughing. I am unsure if I was supposed to be pr

Im a 44yrs old female who took methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it

My boyfriend has just taken 800mg ibuprofen, 150mg of dihydrocodeine, 1000mg of paracetomol and drank alcohol. Will he be ok? his blood pressure is 160/109 pulse 66 resp 12

Can i take Acetaminophen W/Codeine #3 with Metoprolol er succinate 25 mg ?

I am borned with allergy over antibiotics and codeine. when i was 2 yrs old, i have undergone a clinical surgery and drs discovered that i have the allergy. now, i am 29 yrs old and i dnt know i am allergic to what! at 28 yrs old, i have undergone p

I works on my paine better then acetaminophen &amp; codeine phophate 300 /30 mg

It would help if you guys stated if you're taking Plus or Max. I think you all know that both of those medications contain Codeine. Codeine is also known as 3 Methyl Morphine. About 10% of Codeine gets transformed to Morphine in vivo (inside your bod

My advice, never touch them. they are totally addictive and the withdrawals are non explainable. I actually felt suicidal some days. If anyone is reading this, take my advice and stay away from any drug with codeine. I am still not my old self, but d

My doctor started me on 16mgs as had become addicted to codeine that had been prescribed by my doctor for carpal tunnel syndrome, I was on them for about three years and they were on repeat prescription. I stopped taking them and had severe withdraw