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Cyclobenzaprine and Methotrexate

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectCyclobenzaprineMethotrexate
DRUG INEFFECTIVE2.6% 5%
ARTHRALGIA1.8% 3.6%
PAIN3.4% 2.9%
INJECTION SITE PAIN0.8% 3.4%
RHEUMATOID ARTHRITIS0.5% 3.1%
NAUSEA2.9% 2.7%
COMPLETED SUICIDE2.7% 0%
FATIGUE2.5% 2.6%
HEADACHE2.4% 2.4%
PAIN IN EXTREMITY1.7% 2.1%
DYSPNOEA2.1% 1.6%
PYREXIA0.9% 2.1%
DRUG ABUSE2% 0%
FALL1.9% 1.2%
PNEUMONIA1.2% 1.9%
TOXICITY TO VARIOUS AGENTS1.9% 0%
DIARRHOEA1.8% 1.8%
DIZZINESS1.8% 1.2%
ANXIETY1.8% 0.5%
DEPRESSION1.7% 0.6%
VOMITING1.6% 1.6%
MALAISE1.3% 1.6%
BACK PAIN1.6% 1.1%
INJECTION SITE ERYTHEMA0% 1.6%
DEATH1.5% 0.6%
JOINT SWELLING0.5% 1.5%
COUGH1% 1.4%
INSOMNIA1.4% 0.5%
ASTHENIA1.3% 1.2%
RASH1% 1.3%
NASOPHARYNGITIS0.6% 1.3%
CONDITION AGGRAVATED0.9% 1.2%
HYPERTENSION1.2% 0.8%
CHEST PAIN1.2% 0.7%
MUSCLE SPASMS1.2% 0.5%
WEIGHT DECREASED1.1% 1%
SINUSITIS0.7% 1.1%
ABDOMINAL PAIN1% 0.9%
URINARY TRACT INFECTION0.8% 1%
WEIGHT INCREASED1% 0.7%
FEELING ABNORMAL1% 0.6%
PSORIASIS0% 1%
INJECTION SITE PRURITUS0% 1%
DEEP VEIN THROMBOSIS1% 0%
PULMONARY EMBOLISM1% 0%
SOMNOLENCE1% 0%
SEPSIS0% 1%
CONSTIPATION1% 0%
INFECTION0% 1%
GAIT DISTURBANCE0.9% 0.9%
PRURITUS0.9% 0.8%
DRUG DOSE OMISSION0.9% 0.8%
OFF LABEL USE0.7% 0.9%
HYPOAESTHESIA0.9% 0.7%
INJECTION SITE SWELLING0% 0.9%
INJURY0.9% 0%
CARDIAC ARREST0.9% 0%
ANAEMIA0.8% 0.8%
ARTHRITIS0.7% 0.8%
BRONCHITIS0.7% 0.8%
PERIPHERAL SWELLING0.6% 0.8%
ABDOMINAL PAIN UPPER0.8% 0.6%
HYPOTENSION0.8% 0.6%
MYOCARDIAL INFARCTION0.8% 0.5%
ALOPECIA0.5% 0.8%
MUSCULOSKELETAL STIFFNESS0% 0.8%
TREMOR0.8% 0%
INJECTION SITE BRUISING0% 0.8%
CARDIO-RESPIRATORY ARREST0.8% 0%
OEDEMA PERIPHERAL0.7% 0.7%
PARAESTHESIA0.7% 0.6%
DRUG HYPERSENSITIVITY0.7% 0.6%
DECREASED APPETITE0.7% 0.5%
ERYTHEMA0.5% 0.7%
MYALGIA0.7% 0.4%
INJECTION SITE REACTION0% 0.7%
RESPIRATORY ARREST0.7% 0%
CONFUSIONAL STATE0.7% 0%
CEREBROVASCULAR ACCIDENT0.7% 0%
PANCYTOPENIA0% 0.7%
GASTROOESOPHAGEAL REFLUX DISEASE0.7% 0%
DIABETES MELLITUS0.7% 0%
DRUG INTERACTION0.6% 0.6%
HYPERSENSITIVITY0.5% 0.6%
MUSCULOSKELETAL PAIN0.5% 0.6%
CONTUSION0.6% 0.5%
ARTHROPATHY0.5% 0.6%
OSTEOARTHRITIS0.6% 0.5%
MUSCULAR WEAKNESS0.6% 0.4%
FEBRILE NEUTROPENIA0% 0.6%
NEUTROPENIA0% 0.6%
INCORRECT DOSE ADMINISTERED0% 0.6%
OROPHARYNGEAL PAIN0% 0.6%
HEPATIC ENZYME INCREASED0% 0.6%
MIGRAINE0.6% 0%
HYPERHIDROSIS0.6% 0%
OSTEOPOROSIS0.6% 0%
DRY MOUTH0.6% 0%
OVERDOSE0.6% 0%
VISION BLURRED0.6% 0%
DEHYDRATION0.6% 0%
MOBILITY DECREASED0% 0.6%
HERPES ZOSTER0% 0.6%
INFLUENZA0% 0.6%
DRUG EFFECT DECREASED0% 0.6%
INFUSION RELATED REACTION0% 0.6%
MEMORY IMPAIRMENT0.6% 0%
EMOTIONAL DISTRESS0.6% 0%
INJECTION SITE HAEMORRHAGE0% 0.6%
RENAL FAILURE0.5% 0.5%
BLOOD PRESSURE INCREASED0.5% 0.5%
CELLULITIS0% 0.5%
RESPIRATORY FAILURE0% 0.5%
DRUG EFFECT INCOMPLETE0% 0.5%
STOMATITIS0% 0.5%
SWELLING0% 0.5%
CHILLS0% 0.5%
DRUG INTOLERANCE0% 0.5%
THROMBOCYTOPENIA0% 0.5%
ABDOMINAL DISCOMFORT0% 0.5%
LOSS OF CONSCIOUSNESS0.5% 0%
PALPITATIONS0.5% 0%
NECK PAIN0.5% 0%
DYSPEPSIA0.5% 0%
CHRONIC OBSTRUCTIVE PULMONARY DISEASE0.5% 0%
TACHYCARDIA0.5% 0%
FIBROMYALGIA0.5% 0%
INJECTION SITE HAEMATOMA0% 0.4%
INFLAMMATION0% 0.4%
LOCAL SWELLING0% 0.4%
MUCOSAL INFLAMMATION0% 0.4%
URTICARIA0% 0.4%
NEUROPATHY PERIPHERAL0.4% 0%
BLOOD CHOLESTEROL INCREASED0.4% 0%
BALANCE DISORDER0.4% 0%

New treatments are found every day. View current Cyclobenzaprine research studies and Methotrexate clinical trials


Top 5 Cyclobenzaprine Reported Side Effects

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Top 5 Methotrexate Reported Side Effects

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Patient Forum

Recent Comments and Reports

Confusion, ringing of ears, dry (stinging) eyes, nightmares, depression associated with hyper-sensitivity/over-reaction in social events.

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spo

I have been on methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is

I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause diss

I only took it for 21 days but in that time, it put me into a full panic attack that lasted almost 8 days after I went off the medication. I had mental confusion, could not speak properly (I knew what I wanted to say but the words would not come out

I was diagnosed with Rheumatoid Arthritis about 4 years ago when I was 13 or 14, they looked at me and said I had it, they didn't do any blood tests and when they did, nothing showed. But they started me on about 5 mg of Methotrexate, Prednisone, and

Im 16 yrs old and i have a bad lower back and neck so i take cylobenzapr and one time i fell asleep and awoke and was talking but not making no sense

Im a 44yrs old female who took methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it

Painful cough after 2 days of 1st dose lasting-- to date-- 6 days

What did you have?