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Diphenhydramine and Loratadine

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectDiphenhydramineLoratadine
DRUG INEFFECTIVE1.6% 4.3%
TOXICITY TO VARIOUS AGENTS4.2% 0%
COMPLETED SUICIDE4.2% 0%
NAUSEA2.7% 3.2%
FATIGUE2.5% 3.1%
DYSPNOEA2.3% 2.9%
DRUG ABUSE2.9% 0%
HEADACHE2.5% 2.8%
DIZZINESS1.3% 2.7%
DEATH2.6% 0.8%
DIARRHOEA1.8% 2.5%
PAIN1.8% 2.3%
PYREXIA2% 1.3%
SINUSITIS2% 0.8%
VOMITING1.9% 1.8%
OFF LABEL USE1.2% 1.7%
MALAISE1% 1.7%
INFUSION RELATED REACTION1.7% 0%
PNEUMONIA1.6% 1.4%
ASTHENIA1.1% 1.6%
RASH1.4% 1.5%
INSOMNIA0.8% 1.5%
HYPOTENSION1.5% 0.8%
ARTHRALGIA1.4% 1.4%
COUGH1.2% 1.4%
ANXIETY0.9% 1.4%
FALL0.9% 1.4%
PAIN IN EXTREMITY0.8% 1.4%
DEPRESSION0.6% 1.4%
CARDIO-RESPIRATORY ARREST1.4% 0%
CARDIAC ARREST1.4% 0%
PRURITUS1.1% 1.3%
CHEST PAIN0.9% 1.3%
SOMNOLENCE0.7% 1.3%
BACK PAIN0.9% 1.2%
WEIGHT DECREASED0.9% 1.1%
BLOOD PRESSURE INCREASED1.1% 0.7%
OVERDOSE1.1% 0.6%
CONDITION AGGRAVATED0.5% 1.1%
FEELING ABNORMAL0.4% 1.1%
HYPERTENSION1% 1%
WEIGHT INCREASED0.8% 1%
ABDOMINAL PAIN0.8% 1%
URTICARIA0.8% 1%
CONFUSIONAL STATE0.6% 1%
CONSTIPATION0.6% 1%
NASOPHARYNGITIS1% 0.6%
ABDOMINAL PAIN UPPER0.5% 1%
RESPIRATORY ARREST1% 0%
HYPERSENSITIVITY0.7% 0.9%
DECREASED APPETITE0.6% 0.9%
BRONCHITIS0.9% 0.5%
CHILLS0.9% 0.5%
MUSCLE SPASMS0.5% 0.9%
DRUG DOSE OMISSION0% 0.9%
ASTHMA0% 0.9%
URINARY TRACT INFECTION0.8% 0.8%
ANAEMIA0.8% 0.7%
TREMOR0.6% 0.8%
HYPOAESTHESIA0.5% 0.8%
OEDEMA PERIPHERAL0.5% 0.8%
GAIT DISTURBANCE0.4% 0.8%
PALPITATIONS0% 0.8%
TACHYCARDIA0.8% 0%
DRUG INTERACTION0.7% 0.7%
DEHYDRATION0.7% 0.7%
HEART RATE INCREASED0.7% 0.6%
ERYTHEMA0.7% 0.6%
FLUSHING0.7% 0.6%
MYALGIA0.5% 0.7%
HYPERHIDROSIS0.5% 0.7%
PARAESTHESIA0.5% 0.7%
FEBRILE NEUTROPENIA0.7% 0%
UPPER RESPIRATORY TRACT INFECTION0.7% 0%
SEPSIS0.7% 0%
INTENTIONAL OVERDOSE0.7% 0%
INTENTIONAL DRUG MISUSE0.7% 0%
GASTROOESOPHAGEAL REFLUX DISEASE0% 0.7%
DRUG TOXICITY0.7% 0%
LOSS OF CONSCIOUSNESS0.6% 0.6%
DRUG HYPERSENSITIVITY0.6% 0.6%
CHEST DISCOMFORT0.5% 0.6%
VISION BLURRED0% 0.6%
CEREBROVASCULAR ACCIDENT0% 0.6%
OXYGEN SATURATION DECREASED0.6% 0%
RHEUMATOID ARTHRITIS0.6% 0%
INFECTION0.6% 0%
NEUTROPENIA0.6% 0%
INCORRECT DOSE ADMINISTERED0% 0.6%
MYOCARDIAL INFARCTION0% 0.6%
MEMORY IMPAIRMENT0% 0.6%
BLOOD GLUCOSE INCREASED0% 0.6%
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION0% 0.6%
INJECTION SITE PAIN0% 0.6%
ABDOMINAL DISCOMFORT0% 0.6%
DRY MOUTH0% 0.6%
PULMONARY OEDEMA0.6% 0%
SYNCOPE0% 0.6%
THROMBOCYTOPENIA0.6% 0%
PERIPHERAL SWELLING0.5% 0.5%
AGITATION0.5% 0.5%
OROPHARYNGEAL PAIN0.4% 0.5%
ATRIAL FIBRILLATION0.4% 0.5%
INJURY0% 0.5%
BALANCE DISORDER0% 0.5%
PRODUCT USE ISSUE0% 0.5%
PRODUCT QUALITY ISSUE0% 0.5%
EPISTAXIS0% 0.5%
AMNESIA0% 0.5%
SWELLING FACE0% 0.5%
ARTHRITIS0% 0.5%
DIABETES MELLITUS0% 0.5%
MUSCULAR WEAKNESS0% 0.5%
MIGRAINE0% 0.5%
DYSPEPSIA0% 0.5%
EXPIRED PRODUCT ADMINISTERED0% 0.5%
ALOPECIA0% 0.5%
PULMONARY EMBOLISM0% 0.5%
PLEURAL EFFUSION0.5% 0%
JOINT SWELLING0.5% 0%
RESPIRATORY FAILURE0.5% 0%
HAEMOGLOBIN DECREASED0.5% 0%
INFLUENZA0.5% 0%
SUICIDAL IDEATION0% 0.5%
WHITE BLOOD CELL COUNT DECREASED0.5% 0%
POISONING0.5% 0%
GASTROINTESTINAL HAEMORRHAGE0% 0.5%
RENAL FAILURE0.5% 0%
UNRESPONSIVE TO STIMULI0.4% 0%
SUICIDE ATTEMPT0.4% 0%
DYSPHAGIA0.4% 0%
ACCIDENTAL OVERDOSE0.4% 0%

New treatments are found every day. View current Diphenhydramine research studies and Loratadine clinical trials


Top 5 Diphenhydramine Reported Side Effects

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Top 5 Loratadine Reported Side Effects

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Patient Forum

Recent Comments and Reports

one 10 mg pill cuased presure in thechest bad muslespasms in the back think past doses has sent me skizzo

**The reason i reccomend 300-350mg is because i did that ammount 2 times with benadryl and it wasnt the best but i dont think it was horrible, and the second time i did 325mg and mixed it with weed and a few mood helper pills i found at my sisters ho

A few days ago i took 450 mg of diphenhydramine in sleeping pills, i know it is extremely stupid and i regret it 100%, first off when i took it i was very stoned and i thought they were benadryl because all i read was the diphenhydramine, about a hal

Alopecia areata........ anyone else?

Can my one year old take loratadine

Can this medicine cause you to have a very fast heart rate?

Can you take tylenol right after taking a loratadine?

How long should a child of 5 years of age be on Loratadine (liquid form) and will this effect her alertness in school?

I loved these strips. I have had allergic reactions to my own allergy shots. After waiting at the Dr.'s office for 15 minutes after my allergy shot, I leave to go shopping. Sometimes I can feel a little thickening in my throat, similar to when I'v

I was taking the loratadine 24 hr for about 4 months and past 3 months kept losing a lot of hair. Found bald spot few days ago and doc says alopecia areata. I saw a few postings on the internet of a correlation and wanted to know it anyone else has

Is 30mg too much in 24 hours?? is medical advice needed

Ive been taking Diphenhydramine 25-50mgms nightly for some years,and my pharmacist is concerned that there may be some long-term psychological problems if I continue taking them,is this a serious concern?

A few days ago i took 450 mg of diphenhydramine in sleeping pills, i know it is extremely stupid and i regret it 100%, first off when i took it i was very stoned and i thought they were benadryl because all i read was the diphenhydramine, about a hal

Ive been taking Diphenhydramine 25-50mgms nightly for some years,and my pharmacist is concerned that there may be some long-term psychological problems if I continue taking them,is this a serious concern?

Took it at midday the day before (1, 250mg), this morning my face was slightly swollen, my cheeks and lips are tender (tingling). Took some antihistamine (Diphenhydramine). Waiting to see what happens.