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Diphenhydramine and Lyrica

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectDiphenhydramineLyrica
PAIN1.8% 5.4%
DRUG INEFFECTIVE1.6% 5.1%
TOXICITY TO VARIOUS AGENTS4.2% 0.5%
COMPLETED SUICIDE4.2% 0%
DIZZINESS1.3% 3.2%
DRUG ABUSE2.9% 0.4%
WEIGHT INCREASED0.8% 2.8%
NAUSEA2.7% 2.3%
DEATH2.6% 0.8%
FATIGUE2.5% 2.2%
HEADACHE2.5% 2%
SOMNOLENCE0.7% 2.5%
MALAISE1% 2.4%
DYSPNOEA2.3% 1.6%
PAIN IN EXTREMITY0.8% 2.3%
FEELING ABNORMAL0.4% 2.1%
FALL0.9% 2%
PYREXIA2% 0.8%
SINUSITIS2% 0%
VOMITING1.9% 1.3%
INSOMNIA0.8% 1.9%
DIARRHOEA1.8% 1.5%
INFUSION RELATED REACTION1.7% 0%
PNEUMONIA1.6% 1%
GAIT DISTURBANCE0.4% 1.6%
HYPOTENSION1.5% 0.5%
CONDITION AGGRAVATED0.5% 1.5%
VISION BLURRED0% 1.5%
ARTHRALGIA1.4% 1.3%
RASH1.4% 1%
CARDIAC ARREST1.4% 0%
CARDIO-RESPIRATORY ARREST1.4% 0%
ASTHENIA1.1% 1.3%
DEPRESSION0.6% 1.3%
OEDEMA PERIPHERAL0.5% 1.3%
OFF LABEL USE1.2% 1%
ANXIETY0.9% 1.2%
COUGH1.2% 0.6%
BACK PAIN0.9% 1.1%
PRURITUS1.1% 0.8%
OVERDOSE1.1% 0.6%
DRUG HYPERSENSITIVITY0.6% 1.1%
CONFUSIONAL STATE0.6% 1.1%
HYPOAESTHESIA0.5% 1.1%
BLOOD PRESSURE INCREASED1.1% 0.5%
HYPERTENSION1% 0.7%
TREMOR0.6% 1%
PARAESTHESIA0.5% 1%
NASOPHARYNGITIS1% 0.5%
RESPIRATORY ARREST1% 0%
WEIGHT DECREASED0.9% 0.9%
DRUG INTERACTION0.7% 0.9%
CHEST PAIN0.9% 0.6%
MUSCLE SPASMS0.5% 0.9%
CHILLS0.9% 0%
MEMORY IMPAIRMENT0% 0.9%
BRONCHITIS0.9% 0%
CONSTIPATION0.6% 0.8%
ABDOMINAL PAIN0.8% 0.5%
PERIPHERAL SWELLING0.5% 0.8%
ANAEMIA0.8% 0.5%
URINARY TRACT INFECTION0.8% 0.5%
URTICARIA0.8% 0%
BURNING SENSATION0% 0.8%
BALANCE DISORDER0% 0.8%
TACHYCARDIA0.8% 0%
LOSS OF CONSCIOUSNESS0.6% 0.7%
HYPERHIDROSIS0.5% 0.7%
MYALGIA0.5% 0.7%
HYPERSENSITIVITY0.7% 0.5%
DEHYDRATION0.7% 0.5%
ERYTHEMA0.7% 0.4%
DRY MOUTH0% 0.7%
DRUG EFFECT INCOMPLETE0% 0.7%
NEUROPATHY PERIPHERAL0% 0.7%
SUICIDAL IDEATION0% 0.7%
WITHDRAWAL SYNDROME0% 0.7%
DRUG WITHDRAWAL SYNDROME0% 0.7%
UPPER RESPIRATORY TRACT INFECTION0.7% 0%
INTENTIONAL DRUG MISUSE0.7% 0%
INTENTIONAL OVERDOSE0.7% 0%
FLUSHING0.7% 0%
SEPSIS0.7% 0%
FEBRILE NEUTROPENIA0.7% 0%
DRUG TOXICITY0.7% 0%
HEART RATE INCREASED0.7% 0%
DECREASED APPETITE0.6% 0.6%
JOINT SWELLING0.5% 0.6%
DRUG DOSE OMISSION0% 0.6%
FIBROMYALGIA0% 0.6%
DISTURBANCE IN ATTENTION0% 0.6%
MUSCULAR WEAKNESS0% 0.6%
INTENTIONAL PRODUCT MISUSE0% 0.6%
AMNESIA0% 0.6%
SWELLING0% 0.6%
PRODUCT USE ISSUE0% 0.6%
INFECTION0.6% 0%
PULMONARY OEDEMA0.6% 0%
NEUTROPENIA0.6% 0%
OXYGEN SATURATION DECREASED0.6% 0%
THROMBOCYTOPENIA0.6% 0%
RHEUMATOID ARTHRITIS0.6% 0%
ABDOMINAL PAIN UPPER0.5% 0.5%
AGITATION0.5% 0.4%
ACTIVITIES OF DAILY LIVING IMPAIRED0% 0.5%
CONVULSION0% 0.5%
CEREBROVASCULAR ACCIDENT0% 0.5%
BLOOD GLUCOSE INCREASED0% 0.5%
THERAPEUTIC RESPONSE UNEXPECTED0% 0.5%
SPEECH DISORDER0% 0.5%
DRUG INTOLERANCE0% 0.5%
VISUAL IMPAIRMENT0% 0.5%
DIABETES MELLITUS0% 0.5%
NEURALGIA0% 0.5%
INFLUENZA0.5% 0%
POISONING0.5% 0%
RENAL FAILURE0.5% 0%
PLEURAL EFFUSION0.5% 0%
RESPIRATORY FAILURE0.5% 0%
CHEST DISCOMFORT0.5% 0%
WHITE BLOOD CELL COUNT DECREASED0.5% 0%
HAEMOGLOBIN DECREASED0.5% 0%
DYSPHAGIA0.4% 0.4%
SWELLING FACE0% 0.4%
ABDOMINAL DISCOMFORT0% 0.4%
INTENTIONAL PRODUCT USE ISSUE0% 0.4%
ALOPECIA0% 0.4%
ABASIA0% 0.4%
MYOCARDIAL INFARCTION0% 0.4%
ARTHROPATHY0% 0.4%
OEDEMA0% 0.4%
UNRESPONSIVE TO STIMULI0.4% 0%
ATRIAL FIBRILLATION0.4% 0%
SUICIDE ATTEMPT0.4% 0%
ACCIDENTAL OVERDOSE0.4% 0%
OROPHARYNGEAL PAIN0.4% 0%
HALLUCINATION0% 0.4%

New treatments are found every day. View current Diphenhydramine research studies and Lyrica clinical trials


Top 5 Diphenhydramine Reported Side Effects

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Top 5 Lyrica Reported Side Effects

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Patient Forum

Recent Comments and Reports

<span style='font-family: Arial;'>I was subscribed Lyrica for my fibromyalgia and took it for about 3 weeks and as a result I ended up jumping through a window (resulting in permanent injuries) and wound up in a mental inst

Extreme fatigue, sleeplessness, short term memory and speech difficulties, Edema, weight gain, stumbling, shortness of breath, numbness in both legs, and completely kills ability to achieve orgasm.

**The reason i reccomend 300-350mg is because i did that ammount 2 times with benadryl and it wasnt the best but i dont think it was horrible, and the second time i did 325mg and mixed it with weed and a few mood helper pills i found at my sisters ho

A few days ago i took 450 mg of diphenhydramine in sleeping pills, i know it is extremely stupid and i regret it 100%, first off when i took it i was very stoned and i thought they were benadryl because all i read was the diphenhydramine, about a hal

After a little over 2 weeks on Lyrica I awoke one morning with blurred vision. It has been almost 2 weeks and even after stopping the Lyrica I still can not focus my eyes. I am told that my eyes are focusing in and out and if I try hard enough I get

After one dose of 50mg felteuphoric, dizzy,out of touch with reality and extremely depressed; unable to functionas normal.great for pain but don't think I can continue withthis.

Can anyone explain how i can feel euphoric but suicidal at the same time on Lyrica?

Cant sleep,hair loss.depressed

Doctors are told what to prescribe and its ridiculous because they don't test enough on the medication. Pharmaceutical companies want to get a patent asap so its an automatic billion in the bank because of the 18 year patent law.

Does Lyrica really cause weight gain in all patients who take it

Drowsiness, double vision, weight gain

Earlier this month I started Lyrica. Was on only 50mh pr night for 4 nights before I had an allergic reation. Had to stop taking it, took over a week for the allergic symptoms to stop! Just reported to the FDA.

A few days ago i took 450 mg of diphenhydramine in sleeping pills, i know it is extremely stupid and i regret it 100%, first off when i took it i was very stoned and i thought they were benadryl because all i read was the diphenhydramine, about a hal

Ive been taking Diphenhydramine 25-50mgms nightly for some years,and my pharmacist is concerned that there may be some long-term psychological problems if I continue taking them,is this a serious concern?

Took it at midday the day before (1, 250mg), this morning my face was slightly swollen, my cheeks and lips are tender (tingling). Took some antihistamine (Diphenhydramine). Waiting to see what happens.