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Effexor and Methotrexate

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectEffexorMethotrexate
DRUG INEFFECTIVE3.1% 5%
ARTHRALGIA1.1% 3.6%
NAUSEA3.4% 2.7%
INJECTION SITE PAIN0% 3.4%
RHEUMATOID ARTHRITIS0% 3.1%
DEPRESSION3% 0.6%
PAIN2.1% 2.9%
DIZZINESS2.8% 1.2%
ANXIETY2.8% 0.5%
HEADACHE2.7% 2.4%
DRUG WITHDRAWAL SYNDROME2.7% 0%
FATIGUE2.6% 2.6%
INSOMNIA2.2% 0.5%
PAIN IN EXTREMITY1% 2.1%
PYREXIA0.8% 2.1%
FEELING ABNORMAL2% 0.6%
MALAISE1.9% 1.6%
PNEUMONIA0.7% 1.9%
DIARRHOEA1.7% 1.8%
VOMITING1.8% 1.6%
SUICIDAL IDEATION1.8% 0%
DYSPNOEA1.6% 1.6%
FALL1.6% 1.2%
WEIGHT INCREASED1.6% 0.7%
INJECTION SITE ERYTHEMA0% 1.6%
ASTHENIA1.5% 1.2%
JOINT SWELLING0% 1.5%
COUGH0.7% 1.4%
PARAESTHESIA1.4% 0.6%
RASH0.9% 1.3%
NASOPHARYNGITIS0% 1.3%
SOMNOLENCE1.3% 0%
TREMOR1.3% 0%
CONDITION AGGRAVATED1.2% 1.2%
HYPERTENSION1.2% 0.8%
HYPERHIDROSIS1.2% 0%
CONFUSIONAL STATE1.2% 0%
WEIGHT DECREASED1.1% 1%
BACK PAIN0.9% 1.1%
SINUSITIS0% 1.1%
DIABETES MELLITUS1.1% 0%
URINARY TRACT INFECTION0.6% 1%
DRUG INTERACTION1% 0.6%
DRUG HYPERSENSITIVITY1% 0.6%
SEPSIS0% 1%
PSORIASIS0% 1%
INFECTION0% 1%
INJECTION SITE PRURITUS0% 1%
ABDOMINAL PAIN0.8% 0.9%
OFF LABEL USE0.7% 0.9%
GAIT DISTURBANCE0.7% 0.9%
CHEST PAIN0.9% 0.7%
AGITATION0.9% 0%
INJECTION SITE SWELLING0% 0.9%
SUICIDE ATTEMPT0.9% 0%
CRYING0.9% 0%
PRURITUS0.8% 0.8%
DRUG DOSE OMISSION0.6% 0.8%
ANAEMIA0.6% 0.8%
ARTHRITIS0% 0.8%
MUSCULOSKELETAL STIFFNESS0% 0.8%
CONVULSION0.8% 0%
PERIPHERAL SWELLING0% 0.8%
BRONCHITIS0% 0.8%
INJECTION SITE BRUISING0% 0.8%
ALOPECIA0% 0.8%
CONSTIPATION0.8% 0%
HYPOAESTHESIA0.7% 0.7%
OEDEMA PERIPHERAL0.6% 0.7%
ABDOMINAL PAIN UPPER0.7% 0.6%
MUSCLE SPASMS0.7% 0.5%
DECREASED APPETITE0.7% 0.5%
BLOOD PRESSURE INCREASED0.7% 0.5%
MYALGIA0.7% 0.4%
WITHDRAWAL SYNDROME0.7% 0%
IRRITABILITY0.7% 0%
MEMORY IMPAIRMENT0.7% 0%
PANCYTOPENIA0% 0.7%
ERYTHEMA0% 0.7%
OVERDOSE0.7% 0%
TYPE 2 DIABETES MELLITUS0.7% 0%
INJECTION SITE REACTION0% 0.7%
DISTURBANCE IN ATTENTION0.7% 0%
LOSS OF CONSCIOUSNESS0.7% 0%
DRUG EXPOSURE DURING PREGNANCY0.7% 0%
DEATH0.6% 0.6%
HYPOTENSION0.5% 0.6%
MYOCARDIAL INFARCTION0.6% 0.5%
INCORRECT DOSE ADMINISTERED0% 0.6%
FEBRILE NEUTROPENIA0% 0.6%
OROPHARYNGEAL PAIN0% 0.6%
NEUTROPENIA0% 0.6%
CEREBROVASCULAR ACCIDENT0.6% 0%
COMPLETED SUICIDE0.6% 0%
AGGRESSION0.6% 0%
VISION BLURRED0.6% 0%
AMNESIA0.6% 0%
MUSCULOSKELETAL PAIN0% 0.6%
ARTHROPATHY0% 0.6%
HEPATIC ENZYME INCREASED0% 0.6%
INFUSION RELATED REACTION0% 0.6%
MOBILITY DECREASED0% 0.6%
DRUG EFFECT DECREASED0% 0.6%
HYPERSENSITIVITY0% 0.6%
INJECTION SITE HAEMORRHAGE0% 0.6%
INFLUENZA0% 0.6%
HERPES ZOSTER0% 0.6%
NERVOUSNESS0.6% 0%
DEHYDRATION0.6% 0%
PALPITATIONS0.6% 0%
ANGER0.6% 0%
CHILLS0.5% 0.5%
ABDOMINAL DISCOMFORT0.4% 0.5%
CELLULITIS0% 0.5%
RENAL FAILURE0% 0.5%
INTENTIONAL OVERDOSE0.5% 0%
CONTUSION0% 0.5%
HOT FLUSH0.5% 0%
THROMBOCYTOPENIA0% 0.5%
SWELLING0% 0.5%
DRUG INTOLERANCE0% 0.5%
OSTEOARTHRITIS0% 0.5%
GASTROOESOPHAGEAL REFLUX DISEASE0.5% 0%
RESPIRATORY FAILURE0% 0.5%
DRUG EFFECT INCOMPLETE0% 0.5%
ABNORMAL BEHAVIOUR0.5% 0%
MIGRAINE0.5% 0%
BLOOD CHOLESTEROL INCREASED0.5% 0%
DRUG DEPENDENCE0.5% 0%
DRY MOUTH0.5% 0%
BALANCE DISORDER0.5% 0%
VERTIGO0.5% 0%
PANIC ATTACK0.5% 0%
PULMONARY EMBOLISM0.5% 0%
DEPRESSED MOOD0.5% 0%
NIGHTMARE0.5% 0%
UNEVALUABLE EVENT0.5% 0%
STOMATITIS0% 0.5%
INJECTION SITE HAEMATOMA0% 0.4%
LOCAL SWELLING0% 0.4%
INFLAMMATION0% 0.4%
MUSCULAR WEAKNESS0% 0.4%
URTICARIA0% 0.4%
MUCOSAL INFLAMMATION0% 0.4%
HEART RATE INCREASED0.4% 0%
INFLUENZA LIKE ILLNESS0.4% 0%
RESTLESSNESS0.4% 0%
HALLUCINATION0.4% 0%
INJURY0.4% 0%
TINNITUS0.4% 0%

New treatments are found every day. View current Effexor research studies and Methotrexate clinical trials


Top 5 Effexor Reported Side Effects

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Top 5 Methotrexate Reported Side Effects

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Patient Forum

Recent Comments and Reports

10 years on effexor, weight gain of 20 lbs last 5 years when increased to 300mg., no change in cal or exercise, since getting older realized needed fewre calories so tried to reduce like always could wirhWW and exercise, no success, couldn'

Effexor & Pristiq is poison - I would know, I started taking it at 16 yrs old, instead of counselling I was given Effexor by a 'psychiatrist drug dealer' I was never offered counselling. I spent of $25,000 on this medication in my lifetime. D

Effexor raised my blood presure alot ,I had extreme painful headaches,rash that started on my face which was horrible,then spread to my chest,my neck was beat red I itched so badly.I think docotrs need to be more educated on this med before giveing i

Effexor was horrible for me...as soon as I started it I started having panic attacks worse than ever (supposed to help them) scary bad dreams, waking up in a sweat and not knowing who I was, then depression. The first day I expeirenced the panic atta

Ever since i've been prescribed effexor, my systolic bp measurement is high. is there a correlation between the two.

Had effexor yesterday 75 mg not again nusea,blurred vision and today the worst longest headache I have ever had,GP didn't even check my BP before prescription.I am recovering from a fractured skull think I will deal with my depression without drugs

Headaches BAD and very sleepy and increased anxiety

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

Hi.. I have been on effexor. I stopped 'cold turkey'. I know this is wrong. I have gained 25 pounds in the past year. I have increasingly became more depressed. I can't sleep. I have strong thoughts of wanting to die. I don't want to kill myself, but

I agree, this has been a horrile drug experience for me as well .. Effexor should be OFF the market !!!! 46 yr old female, Baltimore MD USA

I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spo

I am taking 300mg of effexor and I believe is it causing dysuria. Could this be correct?

10 years on effexor, weight gain of 20 lbs last 5 years when increased to 300mg., no change in cal or exercise, since getting older realized needed fewre calories so tried to reduce like always could wirhWW and exercise, no success, couldn'

Effexor & Pristiq is poison - I would know, I started taking it at 16 yrs old, instead of counselling I was given Effexor by a 'psychiatrist drug dealer' I was never offered counselling. I spent of $25,000 on this medication in my lifetime. D

Effexor is bad i wish i never started it it should be takeen off the market

Effexor raised my blood presure alot ,I had extreme painful headaches,rash that started on my face which was horrible,then spread to my chest,my neck was beat red I itched so badly.I think docotrs need to be more educated on this med before giveing i

Effexor was horrible for me...as soon as I started it I started having panic attacks worse than ever (supposed to help them) scary bad dreams, waking up in a sweat and not knowing who I was, then depression. The first day I expeirenced the panic atta

Ever since i've been prescribed effexor, my systolic bp measurement is high. is there a correlation between the two.

Had effexor yesterday 75 mg not again nusea,blurred vision and today the worst longest headache I have ever had,GP didn't even check my BP before prescription.I am recovering from a fractured skull think I will deal with my depression without drugs

Hey to all my previous followers. Back on the Champix after going off after 3 wks or so. Spent 4 days smoking my brains out. Big woop that was fun. It stinks. period. I feel aweful. Started taking effexor at the same time now. Should be coping nicely

Hi.. I have been on effexor. I stopped 'cold turkey'. I know this is wrong. I have gained 25 pounds in the past year. I have increasingly became more depressed. I can't sleep. I have strong thoughts of wanting to die. I don't want to kill myself, but

I agree, this has been a horrile drug experience for me as well .. Effexor should be OFF the market !!!! 46 yr old female, Baltimore MD USA