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Fentanyl and Diphenhydramine

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectFentanylDiphenhydramine
DEATH9.2% 2.5%
TOXICITY TO VARIOUS AGENTS7.4% 4.1%
OVERDOSE4.8% 1.1%
COMPLETED SUICIDE0.4% 3.9%
DRUG INEFFECTIVE3.5% 1.7%
PAIN3.2% 1.9%
NAUSEA2.6% 2.7%
DRUG ABUSE2.1% 2.7%
FATIGUE1.5% 2.6%
HEADACHE1% 2.5%
DYSPNOEA1.5% 2.3%
PRODUCT QUALITY ISSUE2.2% 0%
PYREXIA1% 2%
VOMITING1.9% 1.9%
SINUSITIS0% 1.9%
PRODUCT ADHESION ISSUE1.9% 0%
DIARRHOEA1.3% 1.8%
WRONG TECHNIQUE IN DRUG USAGE PROCESS1.8% 0%
INFUSION RELATED REACTION0% 1.7%
PNEUMONIA1% 1.6%
HYPOTENSION1.2% 1.5%
DIZZINESS1.1% 1.4%
CARDIAC ARREST0.8% 1.4%
ARTHRALGIA0.7% 1.4%
OFF LABEL USE0.8% 1.3%
RASH0.7% 1.3%
CARDIO-RESPIRATORY ARREST0.6% 1.3%
MALAISE1.2% 1%
PRURITUS0.5% 1.2%
HYPERHIDROSIS1.2% 0.5%
BLOOD PRESSURE INCREASED0.4% 1.2%
COUGH0% 1.2%
ASTHENIA1% 1.1%
ANXIETY1.1% 0.9%
SOMNOLENCE1.1% 0.8%
DRUG EFFECT DECREASED1.1% 0%
DRUG DOSE OMISSION1.1% 0%
FALL1% 0.9%
DRUG INTERACTION1% 0.7%
HYPERTENSION0.6% 1%
RESPIRATORY ARREST0.5% 1%
DRUG WITHDRAWAL SYNDROME1% 0%
NASOPHARYNGITIS0% 1%
BACK PAIN0.9% 0.9%
WEIGHT DECREASED0.9% 0.9%
ABDOMINAL PAIN0.7% 0.9%
CONSTIPATION0.9% 0.6%
CHEST PAIN0.6% 0.9%
ACCIDENTAL OVERDOSE0.9% 0.5%
TACHYCARDIA0.5% 0.9%
CHILLS0.4% 0.9%
WEIGHT INCREASED0.4% 0.9%
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS0.9% 0%
BRONCHITIS0% 0.9%
INSOMNIA0.8% 0.8%
ANAEMIA0.7% 0.8%
PAIN IN EXTREMITY0.7% 0.8%
CONFUSIONAL STATE0.8% 0.6%
DEPRESSION0.8% 0.6%
URINARY TRACT INFECTION0.5% 0.8%
RENAL FAILURE0.8% 0.5%
WITHDRAWAL SYNDROME0.8% 0%
DRUG DEPENDENCE0.8% 0%
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION0.8% 0%
URTICARIA0% 0.8%
DEHYDRATION0.7% 0.7%
SEPSIS0.5% 0.7%
FEELING ABNORMAL0.7% 0.4%
OXYGEN SATURATION DECREASED0.4% 0.7%
RHEUMATOID ARTHRITIS0% 0.7%
INTENTIONAL OVERDOSE0% 0.7%
DRUG TOXICITY0% 0.7%
FEBRILE NEUTROPENIA0% 0.7%
ERYTHEMA0% 0.7%
UPPER RESPIRATORY TRACT INFECTION0% 0.7%
HEART RATE INCREASED0% 0.7%
HYPERSENSITIVITY0% 0.7%
FLUSHING0% 0.7%
TREMOR0.6% 0.6%
LOSS OF CONSCIOUSNESS0.6% 0.6%
DECREASED APPETITE0.6% 0.6%
CONDITION AGGRAVATED0.5% 0.6%
DRUG HYPERSENSITIVITY0.5% 0.6%
INFECTION0.4% 0.6%
INTENTIONAL DRUG MISUSE0% 0.6%
INJURY0.6% 0%
CHEST DISCOMFORT0% 0.6%
DRUG WITHDRAWAL SYNDROME NEONATAL0.6% 0%
NEUTROPENIA0% 0.6%
HAEMOGLOBIN DECREASED0% 0.6%
PERIPHERAL SWELLING0% 0.6%
MUSCLE SPASMS0.5% 0.5%
AGITATION0.4% 0.5%
HYPOAESTHESIA0.4% 0.5%
OEDEMA PERIPHERAL0.4% 0.5%
RESPIRATORY FAILURE0.5% 0.4%
ABDOMINAL PAIN UPPER0.4% 0.5%
THROMBOCYTOPENIA0.4% 0.5%
ALOPECIA0% 0.5%
PLEURAL EFFUSION0% 0.5%
JOINT SWELLING0% 0.5%
WHITE BLOOD CELL COUNT DECREASED0% 0.5%
PULMONARY OEDEMA0% 0.5%
INFLUENZA0% 0.5%
POISONING0% 0.5%
ATRIAL FIBRILLATION0% 0.5%
MYALGIA0% 0.5%
PARAESTHESIA0% 0.5%
INTENTIONAL PRODUCT MISUSE0.5% 0%
UNEVALUABLE EVENT0.5% 0%
PHARMACEUTICAL PRODUCT COMPLAINT0.5% 0%
MALIGNANT NEOPLASM PROGRESSION0.5% 0%
INADEQUATE ANALGESIA0.5% 0%
UNRESPONSIVE TO STIMULI0.4% 0.4%
BRADYCARDIA0.4% 0%
APPLICATION SITE ERYTHEMA0.4% 0%
SEROTONIN SYNDROME0.4% 0%
SWELLING0% 0.4%
GAIT DISTURBANCE0.4% 0%
PLATELET COUNT DECREASED0% 0.4%
DYSPHAGIA0% 0.4%
RENAL IMPAIRMENT0.4% 0%
DISEASE PROGRESSION0.4% 0%
DEPRESSED LEVEL OF CONSCIOUSNESS0.4% 0%
MYOCARDIAL INFARCTION0.4% 0%
BLOOD PRESSURE DECREASED0.4% 0%
RENAL FAILURE ACUTE0.4% 0%
EMOTIONAL DISTRESS0.4% 0%
APPLICATION SITE PRURITUS0.4% 0%
ANAPHYLACTIC REACTION0.4% 0%
GENERAL PHYSICAL HEALTH DETERIORATION0.4% 0%
FEAR0.4% 0%
MULTI-ORGAN FAILURE0.3% 0%

New treatments are found every day. View current Fentanyl research studies and Diphenhydramine clinical trials


Top 5 Fentanyl Reported Side Effects

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Top 5 Diphenhydramine Reported Side Effects

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Patient Forum

Recent Comments and Reports

**The reason i reccomend 300-350mg is because i did that ammount 2 times with benadryl and it wasnt the best but i dont think it was horrible, and the second time i did 325mg and mixed it with weed and a few mood helper pills i found at my sisters ho

A few days ago i took 450 mg of diphenhydramine in sleeping pills, i know it is extremely stupid and i regret it 100%, first off when i took it i was very stoned and i thought they were benadryl because all i read was the diphenhydramine, about a hal

Been on fantanyl patch 25 mc-for 2 months- just cut back to 12 mc-will i have withdrawal? next week i want to go on NO patch--is this ok?

Cannot sleep for hours after applying a new patch. Also suffer some confusion and depression. By third day the pain relief is poor and I keep falling asleep. Depression is probably the most unpleasant. Also seem to get feverish periods.

I came off fentanyl yesterday after 3 years i also could'nt sleep after applying the patch and had this horrible itchy and restless feeling and terrible nausia the following day i put up with it while it worked but when it started letting the pain th

I loved these strips. I have had allergic reactions to my own allergy shots. After waiting at the Dr.'s office for 15 minutes after my allergy shot, I leave to go shopping. Sometimes I can feel a little thickening in my throat, similar to when I'v

Ive been taking Diphenhydramine 25-50mgms nightly for some years,and my pharmacist is concerned that there may be some long-term psychological problems if I continue taking them,is this a serious concern?

NEVER AGAIN....!! I have never felt more out of control whilst taking these pills. Pounding headaches, nightmares, fear of falling asleep. Who ever came up with this should be locked in a room with the stuff...!!

Since I quit taking the Fentnyl patch I have been diagnosed the depression, anxiety and panic disorder.

Does clindamycin interact with Fentanyl or "industrial-strength" diuretics? Is it possible for clindamycin by itself, or with one of the other 2, or both, to cause a sleep that is almost like unconciousness? My Dad had this happen recently

I came off fentanyl yesterday after 3 years i also could'nt sleep after applying the patch and had this horrible itchy and restless feeling and terrible nausia the following day i put up with it while it worked but when it started letting the pain th

I had partial mastectomy for invasive breast cancer and a sentinel lymph node removal. Endone was fabulous. They tried Fentanyl for burning pain deep in the cuts, then morphine - usless. Within 10-15 minutes of 10mg Endone tablets @8pm, the burning p

Is the fentanyl patch excreted through the skin? i have a 4 month old grandson and i dont want him getting the meds.

My pm doctor started me on Opana 5mg 3xdaily. I have been on Fentanyl 50mcg patch for 3 years. I just started the Opana 4 days ago. I truly feel like I have died and went to hell.This drug should be banned.The side effects are horrific, muscle aches,

While undergoing a trial for an intrathecal pain pump (in my spine) my doctor added bupivacaine to the fentanyl medication. I wasn't even informed that the medication was added. Within minutes I began havingexcruciating, burning pain in my