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Klonopin and Methotrexate

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectKlonopinMethotrexate
DRUG INEFFECTIVE3.5% 4.9%
ARTHRALGIA1.2% 3.6%
INJECTION SITE PAIN0.5% 3.5%
NAUSEA3% 2.7%
RHEUMATOID ARTHRITIS0% 3%
PAIN2.3% 2.9%
FATIGUE2.8% 2.5%
ANXIETY2.7% 0.5%
HEADACHE2.6% 2.4%
DEPRESSION2.5% 0.6%
DIZZINESS2.3% 1.2%
INSOMNIA2.3% 0.6%
PAIN IN EXTREMITY1.2% 2.1%
PYREXIA1.1% 2.1%
DIARRHOEA1.9% 1.8%
FALL1.9% 1.2%
PNEUMONIA1.1% 1.9%
DYSPNOEA1.8% 1.6%
VOMITING1.7% 1.6%
INJECTION SITE ERYTHEMA0% 1.7%
MALAISE1.6% 1.6%
ASTHENIA1.6% 1.2%
WEIGHT INCREASED1.6% 0.7%
COMPLETED SUICIDE1.6% 0%
SOMNOLENCE1.6% 0%
FEELING ABNORMAL1.5% 0.6%
JOINT SWELLING0% 1.5%
WEIGHT DECREASED1.4% 1%
COUGH0.8% 1.4%
NASOPHARYNGITIS0.5% 1.4%
RASH1% 1.3%
TREMOR1.3% 0%
CONDITION AGGRAVATED1% 1.2%
SINUSITIS0.5% 1.2%
BACK PAIN1.1% 1.1%
OFF LABEL USE1.1% 0.8%
DEATH1.1% 0.6%
CONVULSION1.1% 0%
CONFUSIONAL STATE1.1% 0%
SUICIDAL IDEATION1.1% 0%
GAIT DISTURBANCE1% 0.9%
CHEST PAIN1% 0.7%
URINARY TRACT INFECTION0.7% 1%
DRUG INTERACTION1% 0.6%
PSORIASIS0% 1%
SEPSIS0% 1%
TOXICITY TO VARIOUS AGENTS1% 0%
INFECTION0% 1%
INJECTION SITE PRURITUS0% 1%
ABDOMINAL PAIN0.9% 0.9%
HYPERTENSION0.9% 0.8%
PRURITUS0.9% 0.8%
DRUG DOSE OMISSION0.9% 0.8%
MUSCLE SPASMS0.9% 0.5%
INJECTION SITE SWELLING0% 0.9%
CONSTIPATION0.9% 0%
OVERDOSE0.9% 0%
DIABETES MELLITUS0.9% 0%
HYPOAESTHESIA0.8% 0.7%
OEDEMA PERIPHERAL0.7% 0.8%
ABDOMINAL PAIN UPPER0.8% 0.6%
ANAEMIA0.6% 0.8%
PARAESTHESIA0.8% 0.6%
DECREASED APPETITE0.8% 0.5%
INJECTION SITE BRUISING0% 0.8%
BRONCHITIS0% 0.8%
MUSCULOSKELETAL STIFFNESS0% 0.8%
ARTHRITIS0% 0.8%
AGITATION0.8% 0%
LOSS OF CONSCIOUSNESS0.8% 0%
DRUG WITHDRAWAL SYNDROME0.8% 0%
HYPERHIDROSIS0.8% 0%
MEMORY IMPAIRMENT0.8% 0%
HYPOTENSION0.7% 0.6%
ALOPECIA0.5% 0.7%
BLOOD PRESSURE INCREASED0.7% 0.5%
ERYTHEMA0.4% 0.7%
PERIPHERAL SWELLING0% 0.7%
CARDIAC ARREST0.7% 0%
PANCYTOPENIA0% 0.7%
VISION BLURRED0.7% 0%
SUICIDE ATTEMPT0.7% 0%
INJECTION SITE REACTION0% 0.7%
INCORRECT DOSE ADMINISTERED0% 0.7%
MUSCULAR WEAKNESS0.6% 0.4%
MYALGIA0.6% 0.4%
ARTHROPATHY0% 0.6%
INJECTION SITE HAEMORRHAGE0% 0.6%
INFLUENZA0% 0.6%
DRUG HYPERSENSITIVITY0% 0.6%
HERPES ZOSTER0% 0.6%
MUSCULOSKELETAL PAIN0% 0.6%
NEUTROPENIA0% 0.6%
INFUSION RELATED REACTION0% 0.6%
HYPERSENSITIVITY0% 0.6%
OROPHARYNGEAL PAIN0% 0.6%
DRUG EFFECT DECREASED0% 0.6%
FEBRILE NEUTROPENIA0% 0.6%
MOBILITY DECREASED0% 0.6%
HEPATIC ENZYME INCREASED0% 0.6%
DRUG ABUSE0.6% 0%
TYPE 2 DIABETES MELLITUS0.6% 0%
DEHYDRATION0.6% 0%
BALANCE DISORDER0.6% 0%
PALPITATIONS0.6% 0%
AMNESIA0.6% 0%
IRRITABILITY0.6% 0%
CONTUSION0.5% 0.5%
ABDOMINAL DISCOMFORT0.5% 0.5%
MYOCARDIAL INFARCTION0.5% 0.5%
CHILLS0.4% 0.5%
THROMBOCYTOPENIA0% 0.5%
OSTEOARTHRITIS0% 0.5%
STOMATITIS0% 0.5%
DRUG INTOLERANCE0% 0.5%
INJECTION SITE HAEMATOMA0% 0.5%
URTICARIA0% 0.5%
RENAL FAILURE0% 0.5%
RESPIRATORY FAILURE0% 0.5%
SWELLING0% 0.5%
CELLULITIS0% 0.5%
RESPIRATORY ARREST0.5% 0%
NERVOUSNESS0.5% 0%
CARDIO-RESPIRATORY ARREST0.5% 0%
BLOOD GLUCOSE INCREASED0.5% 0%
HALLUCINATION0.5% 0%
GASTROOESOPHAGEAL REFLUX DISEASE0.5% 0%
STRESS0.5% 0%
PRODUCT QUALITY ISSUE0.5% 0%
CRYING0.5% 0%
BLOOD CHOLESTEROL INCREASED0.5% 0%
MIGRAINE0.5% 0%
DRY MOUTH0.5% 0%
PANIC ATTACK0.5% 0%
SEIZURE0.5% 0%
HEART RATE INCREASED0.5% 0%
DYSPHAGIA0.5% 0%
AGGRESSION0.5% 0%
LOCAL SWELLING0% 0.4%
INFLAMMATION0% 0.4%
DRUG EFFECT INCOMPLETE0% 0.4%
LETHARGY0.4% 0%
DISTURBANCE IN ATTENTION0.4% 0%
MUCOSAL INFLAMMATION0% 0.4%

New treatments are found every day. View current Klonopin research studies and Methotrexate clinical trials


Top 5 Klonopin Reported Side Effects

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Top 5 Methotrexate Reported Side Effects

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Patient Forum

Recent Comments and Reports

After taking a large amount of Klonopin to sleep, I have not been able to speak coherently. I can think of what I want to say, but cannot verbalize anything. Anyone know about this or how long it will last?

Am taking klonopin for restless leg syndrome (1 mg. at night) this causese debilitating daytime fatigue and constipation

Ancle at night right leg jiggled every 6 or 7 seconds when I tried to get to sleep. Klonopin at night stopped the jiggling.

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spo

I have been on methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is

I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause diss

I only took it for 21 days but in that time, it put me into a full panic attack that lasted almost 8 days after I went off the medication. I had mental confusion, could not speak properly (I knew what I wanted to say but the words would not come out

I was diagnosed with Rheumatoid Arthritis about 4 years ago when I was 13 or 14, they looked at me and said I had it, they didn't do any blood tests and when they did, nothing showed. But they started me on about 5 mg of Methotrexate, Prednisone, and

Im a 44yrs old female who took methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it

Painful cough after 2 days of 1st dose lasting-- to date-- 6 days

,my sister took one quarter of my suboxone and does not take any opiates. she has been dizzy and throwig up since yesterday she also takes klonopin,ambien,seroquel, and a anti depressant along with several beers since yesterday. she is panicing becau

After taking a large amount of Klonopin to sleep, I have not been able to speak coherently. I can think of what I want to say, but cannot verbalize anything. Anyone know about this or how long it will last?

Am taking klonopin for restless leg syndrome (1 mg. at night) this causese debilitating daytime fatigue and constipation

Ancle at night right leg jiggled every 6 or 7 seconds when I tried to get to sleep. Klonopin at night stopped the jiggling.

I take this because my stupid Indian doctor took me off of Klonopin and put me on Depakote. The Depakote damaged my liver and so he replaced it with Gabapentin. He said that he took the Klonopin because 'it can be addictive'. Lol. Well, I wander why?