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Methotrexate and Fentanyl

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectMethotrexateFentanyl
DRUG INEFFECTIVE5% 3.8%
PAIN2.9% 3.9%
ARTHRALGIA3.6% 0.8%
NAUSEA2.7% 3.4%
INJECTION SITE PAIN3.4% 0%
RHEUMATOID ARTHRITIS3.1% 0%
DEATH0.6% 2.7%
FATIGUE2.6% 1.8%
VOMITING1.6% 2.4%
HEADACHE2.4% 1.2%
WRONG TECHNIQUE IN DRUG USAGE PROCESS0% 2.2%
PYREXIA2.1% 1.3%
PAIN IN EXTREMITY2.1% 0.8%
PRODUCT QUALITY ISSUE0% 2%
PNEUMONIA1.9% 1.3%
DYSPNOEA1.6% 1.8%
DIARRHOEA1.8% 1.6%
TOXICITY TO VARIOUS AGENTS0% 1.7%
DRUG ABUSE0% 1.7%
MALAISE1.6% 1.3%
HYPOTENSION0.6% 1.6%
INJECTION SITE ERYTHEMA1.6% 0%
ANXIETY0.5% 1.5%
OVERDOSE0% 1.5%
JOINT SWELLING1.5% 0%
PRODUCT ADHESION ISSUE0% 1.5%
DIZZINESS1.2% 1.4%
DRUG EFFECT DECREASED0.6% 1.4%
COUGH1.4% 0%
SOMNOLENCE0% 1.4%
ASTHENIA1.2% 1.3%
RASH1.3% 0.8%
DRUG INTERACTION0.6% 1.3%
DRUG WITHDRAWAL SYNDROME0% 1.3%
HYPERHIDROSIS0% 1.3%
NASOPHARYNGITIS1.3% 0%
FALL1.2% 1.2%
BACK PAIN1.1% 1.2%
CONDITION AGGRAVATED1.2% 0.6%
RENAL FAILURE0.5% 1.2%
CARDIAC ARREST0% 1.2%
WEIGHT DECREASED1% 1.1%
SINUSITIS1.1% 0%
CONSTIPATION0% 1.1%
ABDOMINAL PAIN0.9% 1%
SEPSIS1% 0.7%
DEPRESSION0.6% 1%
URINARY TRACT INFECTION1% 0.6%
INSOMNIA0.5% 1%
INJECTION SITE PRURITUS1% 0%
INFECTION1% 0%
CONFUSIONAL STATE0% 1%
PSORIASIS1% 0%
OFF LABEL USE0.9% 0.9%
FEELING ABNORMAL0.6% 0.9%
GAIT DISTURBANCE0.9% 0.5%
LOSS OF CONSCIOUSNESS0% 0.9%
INJECTION SITE SWELLING0.9% 0%
INJURY0% 0.9%
ANAEMIA0.8% 0.8%
HYPERTENSION0.8% 0.8%
DRUG DOSE OMISSION0.8% 0.6%
PRURITUS0.8% 0.6%
DECREASED APPETITE0.5% 0.8%
BRONCHITIS0.8% 0%
ALOPECIA0.8% 0%
MUSCULOSKELETAL STIFFNESS0.8% 0%
INJECTION SITE BRUISING0.8% 0%
ARTHRITIS0.8% 0%
UNEVALUABLE EVENT0% 0.8%
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION0% 0.8%
DEHYDRATION0% 0.8%
WITHDRAWAL SYNDROME0% 0.8%
INADEQUATE ANALGESIA0% 0.8%
PERIPHERAL SWELLING0.8% 0%
CHEST PAIN0.7% 0.7%
OEDEMA PERIPHERAL0.7% 0.6%
RESPIRATORY FAILURE0.5% 0.7%
HYPOAESTHESIA0.7% 0.5%
TREMOR0% 0.7%
RESPIRATORY ARREST0% 0.7%
CARDIO-RESPIRATORY ARREST0% 0.7%
PANCYTOPENIA0.7% 0%
ERYTHEMA0.7% 0%
WEIGHT INCREASED0.7% 0%
INJECTION SITE REACTION0.7% 0%
DRUG HYPERSENSITIVITY0.6% 0.6%
MUSCLE SPASMS0.5% 0.6%
ABDOMINAL PAIN UPPER0.6% 0.5%
AGITATION0% 0.6%
UNRESPONSIVE TO STIMULI0% 0.6%
RENAL FAILURE ACUTE0% 0.6%
MULTI-ORGAN FAILURE0% 0.6%
PHARMACEUTICAL PRODUCT COMPLAINT0% 0.6%
TACHYCARDIA0% 0.6%
INFLUENZA0.6% 0%
INJECTION SITE HAEMORRHAGE0.6% 0%
HERPES ZOSTER0.6% 0%
PARAESTHESIA0.6% 0%
HYPERSENSITIVITY0.6% 0%
ARTHROPATHY0.6% 0%
MUSCULOSKELETAL PAIN0.6% 0%
INCORRECT DOSE ADMINISTERED0.6% 0%
FEBRILE NEUTROPENIA0.6% 0%
OROPHARYNGEAL PAIN0.6% 0%
NEUTROPENIA0.6% 0%
HEPATIC ENZYME INCREASED0.6% 0%
INFUSION RELATED REACTION0.6% 0%
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS0% 0.6%
BRADYCARDIA0% 0.6%
EMOTIONAL DISTRESS0% 0.6%
COMPLETED SUICIDE0% 0.6%
FEAR0% 0.6%
MOBILITY DECREASED0.6% 0%
SEROTONIN SYNDROME0% 0.6%
RENAL IMPAIRMENT0% 0.6%
THROMBOCYTOPENIA0.5% 0.5%
BLOOD PRESSURE INCREASED0.5% 0.5%
CHILLS0.5% 0.5%
ANAPHYLACTIC REACTION0% 0.5%
PULMONARY OEDEMA0% 0.5%
STRESS0% 0.5%
CONVULSION0% 0.5%
BLOOD PRESSURE DECREASED0% 0.5%
OXYGEN SATURATION DECREASED0% 0.5%
APPLICATION SITE ERYTHEMA0% 0.5%
INTENTIONAL DRUG MISUSE0% 0.5%
MALIGNANT NEOPLASM PROGRESSION0% 0.5%
RESPIRATORY DEPRESSION0% 0.5%
STOMATITIS0.5% 0%
MYOCARDIAL INFARCTION0.5% 0%
SWELLING0.5% 0%
DRUG INTOLERANCE0.5% 0%
OSTEOARTHRITIS0.5% 0%
ABDOMINAL DISCOMFORT0.5% 0%
CONTUSION0.5% 0%
CELLULITIS0.5% 0%
APPLICATION SITE PRURITUS0% 0.5%
DELIRIUM0% 0.5%
ANHEDONIA0% 0.5%
RENAL INJURY0% 0.5%
DRUG EFFECT INCOMPLETE0.5% 0%
HAEMOGLOBIN DECREASED0% 0.5%
DRUG TOXICITY0% 0.5%
LOCAL SWELLING0.4% 0%
MUCOSAL INFLAMMATION0.4% 0%
URTICARIA0.4% 0%
INJECTION SITE HAEMATOMA0.4% 0%
MUSCULAR WEAKNESS0.4% 0%
MYALGIA0.4% 0%
INFLAMMATION0.4% 0%

New treatments are found every day. View current Methotrexate research studies and Fentanyl clinical trials


Top 5 Methotrexate Reported Side Effects

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Patient Forum

Recent Comments and Reports

Been on fantanyl patch 25 mc-for 2 months- just cut back to 12 mc-will i have withdrawal? next week i want to go on NO patch--is this ok?

Cannot sleep for hours after applying a new patch. Also suffer some confusion and depression. By third day the pain relief is poor and I keep falling asleep. Depression is probably the most unpleasant. Also seem to get feverish periods.

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spo

I came off fentanyl yesterday after 3 years i also could'nt sleep after applying the patch and had this horrible itchy and restless feeling and terrible nausia the following day i put up with it while it worked but when it started letting the pain th

I have been on methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is

I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause diss

I only took it for 21 days but in that time, it put me into a full panic attack that lasted almost 8 days after I went off the medication. I had mental confusion, could not speak properly (I knew what I wanted to say but the words would not come out

I was diagnosed with Rheumatoid Arthritis about 4 years ago when I was 13 or 14, they looked at me and said I had it, they didn't do any blood tests and when they did, nothing showed. But they started me on about 5 mg of Methotrexate, Prednisone, and

Im a 44yrs old female who took methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it

Painful cough after 2 days of 1st dose lasting-- to date-- 6 days

Dear fellow members, Dioscoredes is a post doc biochemist looking for the cause of his daughters ab-reaction to a range of cytotoxic immuno-suppresants. She has been variously treated with mycophenolate, methotrexate, cyclophosphamide all with th

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

Hi, just wondering if anyone else had experienced severe stomach cramping several days after discontinuing METHOTREXATE? My daughter is 10 and going through this right now. Her Rheumy thinks it's all in her head. As a parent, I know better.

I have ankylosing spondilitis. I had severe side effects to methotrexate. like all possible side effects i mean suicide thoughts and depression the whole nine yards. Have been on Enbrel for almost two years and have seen spectacular results it was sa

I have been on methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is

I have had RA for 15 years and have been on numerous and various meds. I have stoped methotrexate and folic acid and now started taking Leflunomide (Arava). Three days in and I'm noticing I have alot more energy. I was o

I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause diss

I was diagnosed with Rheumatoid Arthritis about 4 years ago when I was 13 or 14, they looked at me and said I had it, they didn't do any blood tests and when they did, nothing showed. But they started me on about 5 mg of Methotrexate, Prednisone, and

Im a 44yrs old female who took methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.

Should a person with severe psoraisis be tested for Hep C before starting methotrexate or cyclosporin?