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Methotrexate and Zyrtec

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectMethotrexateZyrtec
DRUG INEFFECTIVE4.9% 4.3%
ARTHRALGIA3.6% 1.4%
INJECTION SITE PAIN3.5% 0.8%
NAUSEA2.7% 3.2%
FATIGUE2.5% 3%
HEADACHE2.4% 3%
RHEUMATOID ARTHRITIS3% 0%
PAIN2.9% 2.4%
DYSPNOEA1.6% 2.5%
OFF LABEL USE0.8% 2.5%
DIZZINESS1.2% 2.3%
PAIN IN EXTREMITY2.1% 1.2%
PYREXIA2.1% 1.2%
PRURITUS0.8% 2.1%
PRODUCT USE ISSUE0% 2.1%
DIARRHOEA1.8% 2%
PNEUMONIA1.9% 1%
VOMITING1.6% 1.7%
INJECTION SITE ERYTHEMA1.7% 0.5%
ANXIETY0.5% 1.7%
SOMNOLENCE0% 1.7%
MALAISE1.6% 1.5%
RASH1.3% 1.6%
COUGH1.4% 1.5%
INSOMNIA0.6% 1.5%
JOINT SWELLING1.5% 0%
NASOPHARYNGITIS1.4% 0.7%
DEPRESSION0.6% 1.4%
URTICARIA0.5% 1.4%
ASTHENIA1.2% 1.3%
PRODUCT QUALITY ISSUE0% 1.3%
SINUSITIS1.2% 1.1%
FALL1.2% 1.1%
CONDITION AGGRAVATED1.2% 0.9%
FEELING ABNORMAL0.6% 1.2%
THERAPEUTIC RESPONSE UNEXPECTED0% 1.2%
BACK PAIN1.1% 1%
HYPERSENSITIVITY0.6% 1.1%
WEIGHT DECREASED1% 1%
ABDOMINAL PAIN0.9% 1%
CHEST PAIN0.7% 1%
WEIGHT INCREASED0.7% 1%
ABDOMINAL PAIN UPPER0.6% 1%
URINARY TRACT INFECTION1% 0.6%
INFECTION1% 0%
INJECTION SITE PRURITUS1% 0%
ASTHMA0% 1%
SEPSIS1% 0%
PSORIASIS1% 0%
HYPERTENSION0.8% 0.9%
GAIT DISTURBANCE0.9% 0.6%
INJECTION SITE SWELLING0.9% 0%
OEDEMA PERIPHERAL0.8% 0.8%
BRONCHITIS0.8% 0.7%
ERYTHEMA0.7% 0.8%
INCORRECT DOSE ADMINISTERED0.7% 0.8%
DRUG DOSE OMISSION0.8% 0.7%
ANAEMIA0.8% 0.6%
PARAESTHESIA0.6% 0.8%
MUSCLE SPASMS0.5% 0.8%
INJECTION SITE BRUISING0.8% 0%
MUSCULOSKELETAL STIFFNESS0.8% 0%
CONSTIPATION0% 0.8%
ARTHRITIS0.8% 0%
HYPOAESTHESIA0.7% 0.7%
ALOPECIA0.7% 0.5%
DECREASED APPETITE0.5% 0.7%
MYALGIA0.4% 0.7%
TREMOR0% 0.7%
CHEST DISCOMFORT0% 0.7%
INJECTION SITE REACTION0.7% 0%
PERIPHERAL SWELLING0.7% 0%
PANCYTOPENIA0.7% 0%
DRUG HYPERSENSITIVITY0.6% 0.6%
HYPOTENSION0.6% 0.5%
OROPHARYNGEAL PAIN0.6% 0.5%
BLOOD PRESSURE INCREASED0.5% 0.6%
ABDOMINAL DISCOMFORT0.5% 0.6%
BLOOD GLUCOSE INCREASED0% 0.6%
HYPERHIDROSIS0% 0.6%
PALPITATIONS0% 0.6%
FLUSHING0% 0.6%
INJURY0% 0.6%
GASTROOESOPHAGEAL REFLUX DISEASE0% 0.6%
OVERDOSE0% 0.6%
PULMONARY EMBOLISM0% 0.6%
DEHYDRATION0% 0.6%
VISION BLURRED0% 0.6%
DRUG INEFFECTIVE FOR UNAPPROVED INDICATION0% 0.6%
DEEP VEIN THROMBOSIS0% 0.6%
MIGRAINE0% 0.6%
INFUSION RELATED REACTION0.6% 0%
HEPATIC ENZYME INCREASED0.6% 0%
DEATH0.6% 0%
DRUG EFFECT DECREASED0.6% 0%
DRUG INTERACTION0.6% 0%
HERPES ZOSTER0.6% 0%
ARTHROPATHY0.6% 0%
FEBRILE NEUTROPENIA0.6% 0%
NEUTROPENIA0.6% 0%
MUSCULOSKELETAL PAIN0.6% 0%
INJECTION SITE HAEMORRHAGE0.6% 0%
MOBILITY DECREASED0.6% 0%
INFLUENZA0.6% 0%
CONTUSION0.5% 0.5%
CHILLS0.5% 0.5%
MYOCARDIAL INFARCTION0.5% 0.4%
DYSPEPSIA0% 0.5%
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION0% 0.5%
CONFUSIONAL STATE0% 0.5%
MEMORY IMPAIRMENT0% 0.5%
CEREBROVASCULAR ACCIDENT0% 0.5%
HEART RATE INCREASED0% 0.5%
LOSS OF CONSCIOUSNESS0% 0.5%
WHEEZING0% 0.5%
DRUG INTOLERANCE0.5% 0%
DYSGEUSIA0% 0.5%
DRY MOUTH0% 0.5%
CELLULITIS0.5% 0%
SWELLING0.5% 0%
OSTEOARTHRITIS0.5% 0%
THROMBOCYTOPENIA0.5% 0%
RESPIRATORY FAILURE0.5% 0%
STOMATITIS0.5% 0%
RENAL FAILURE0.5% 0%
INJECTION SITE HAEMATOMA0.5% 0%
MUSCULAR WEAKNESS0.4% 0.4%
SUICIDAL IDEATION0% 0.4%
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS0% 0.4%
DYSPHAGIA0% 0.4%
EMOTIONAL DISTRESS0% 0.4%
WRONG PATIENT RECEIVED MEDICATION0% 0.4%
RHINORRHOEA0% 0.4%
CONVULSION0% 0.4%
LOCAL SWELLING0.4% 0%
DRUG EFFECT INCOMPLETE0.4% 0%
MUCOSAL INFLAMMATION0.4% 0%
INFLAMMATION0.4% 0%
ABDOMINAL DISTENSION0% 0.4%

New treatments are found every day. View current Methotrexate research studies and Zyrtec clinical trials


Top 5 Methotrexate Reported Side Effects

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Patient Forum

Recent Comments and Reports

Bad gastritis or abdominal pain; had to get into tub with hot shower on my belly;never had a worse experience or pain; thought I was going to die; malaise; moderate ear pain

Does Zyrtec inrease blood sugar levels? I have been taking 10m a day for 10 days and have notices symptoms of high blood sugar, when tested it was in the high 100's. Has anyone heard of this side effect?

Have you had him checked for P.A.N.D.A.S which is a syndrome related to strep throat. One major symptom can be sudden onset of Tourette's. ALso can cause OCD, depression, and other psychiatric conditions. My son has it. SOme doctors don't believe in

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spo

I have a 12 year old son who took Zyrtec for year-round allergies. He now has tourettes syndrome and westrongly feelthe Zyrtec played a role in this health issue. I started searching the web for info regarding

I have been on methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is

I have had and am having a bad reaction to Zyrtec. My eyes are inflamed and my throat is sore. Lips are swollen. My tongue is white. I will be forced to go to the Emergency at the hospital.

I have Type 2 Diabetes, when taking my level in the morning I noticed my level was elevated, and the only thing I had ingested was a Zyrtec pill about 2 hours prior? Could the pill be the cause?

I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause diss

I only took it for 21 days but in that time, it put me into a full panic attack that lasted almost 8 days after I went off the medication. I had mental confusion, could not speak properly (I knew what I wanted to say but the words would not come out

I took one dose and experienced a bout of pancreatitis. I suffer from chronic pancreatitis and know what most of my 'triggers' are.....never thought a simple allergy medication would cause such a problem, I think I would rather suffer allergies than

Dear fellow members, Dioscoredes is a post doc biochemist looking for the cause of his daughters ab-reaction to a range of cytotoxic immuno-suppresants. She has been variously treated with mycophenolate, methotrexate, cyclophosphamide all with th

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

Hi, just wondering if anyone else had experienced severe stomach cramping several days after discontinuing METHOTREXATE? My daughter is 10 and going through this right now. Her Rheumy thinks it's all in her head. As a parent, I know better.

I have ankylosing spondilitis. I had severe side effects to methotrexate. like all possible side effects i mean suicide thoughts and depression the whole nine yards. Have been on Enbrel for almost two years and have seen spectacular results it was sa

I have been on methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is

I have had RA for 15 years and have been on numerous and various meds. I have stoped methotrexate and folic acid and now started taking Leflunomide (Arava). Three days in and I'm noticing I have alot more energy. I was o

I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause diss

I was diagnosed with Rheumatoid Arthritis about 4 years ago when I was 13 or 14, they looked at me and said I had it, they didn't do any blood tests and when they did, nothing showed. But they started me on about 5 mg of Methotrexate, Prednisone, and

Im a 44yrs old female who took methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.

Should a person with severe psoraisis be tested for Hep C before starting methotrexate or cyclosporin?