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Nexium and Methotrexate

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectNexiumMethotrexate
DRUG INEFFECTIVE3.5% 7.1%
CHRONIC KIDNEY DISEASE4.5% 0%
DRUG DOSE OMISSION4.1% 0.7%
ARTHRALGIA1.2% 3.5%
RHEUMATOID ARTHRITIS0% 3.3%
GASTROOESOPHAGEAL REFLUX DISEASE3.1% 0%
NAUSEA2.9% 2.7%
PAIN2.3% 2.9%
INJECTION SITE PAIN0% 2.8%
FATIGUE1.8% 2.5%
MALAISE2.5% 1.6%
HEADACHE1.8% 2.3%
DIARRHOEA2.2% 1.7%
VOMITING2% 1.6%
PAIN IN EXTREMITY1.1% 2%
ACUTE KIDNEY INJURY2% 0%
DYSPEPSIA2% 0%
DYSPNOEA1.9% 1.5%
PYREXIA1% 1.9%
PNEUMONIA1.1% 1.7%
OFF LABEL USE1.7% 1%
DIZZINESS1.6% 1.1%
JOINT SWELLING0% 1.6%
FALL1.5% 1.2%
ABDOMINAL PAIN UPPER1.5% 0.6%
RENAL FAILURE1.5% 0.4%
COUGH1% 1.3%
RASH0.8% 1.3%
CONDITION AGGRAVATED0.7% 1.3%
CHEST PAIN1.3% 0.7%
INJECTION SITE ERYTHEMA0% 1.3%
ASTHENIA1.2% 1.1%
WEIGHT DECREASED1.2% 1%
DRUG HYPERSENSITIVITY0.5% 1.2%
NASOPHARYNGITIS0.5% 1.2%
HYPERTENSION1.1% 0.8%
ABDOMINAL DISCOMFORT1.1% 0.7%
DEPRESSION1.1% 0.6%
ANXIETY1.1% 0.5%
DEATH1.1% 0.5%
INSOMNIA1.1% 0.5%
OSTEOPOROSIS1.1% 0%
BACK PAIN1% 1%
ABDOMINAL PAIN1% 0.9%
FEELING ABNORMAL1% 0.5%
SINUSITIS0.5% 1%
PSORIASIS0% 1%
INTENTIONAL PRODUCT MISUSE1% 0%
END STAGE RENAL DISEASE1% 0%
INFECTION0% 1%
DRUG INTOLERANCE0% 1%
ANAEMIA0.9% 0.7%
GAIT DISTURBANCE0.6% 0.9%
URINARY TRACT INFECTION0.6% 0.9%
PERIPHERAL SWELLING0% 0.9%
MUSCULOSKELETAL STIFFNESS0% 0.9%
ALOPECIA0% 0.9%
SEPSIS0% 0.9%
PRURITUS0.8% 0.8%
ARTHRITIS0.7% 0.8%
MYOCARDIAL INFARCTION0.8% 0.4%
TREATMENT FAILURE0% 0.8%
INTENTIONAL DRUG MISUSE0.8% 0%
INJECTION SITE PRURITUS0% 0.8%
DRUG EFFECT DECREASED0% 0.8%
CONSTIPATION0.8% 0%
DRUG EFFECT INCOMPLETE0% 0.8%
WEIGHT INCREASED0.7% 0.7%
OEDEMA PERIPHERAL0.7% 0.6%
DECREASED APPETITE0.7% 0.5%
BRONCHITIS0.5% 0.7%
ERYTHEMA0.4% 0.7%
MUSCLE SPASMS0.7% 0.4%
DIABETES MELLITUS0.7% 0%
INJECTION SITE REACTION0% 0.7%
PANCYTOPENIA0% 0.7%
CEREBROVASCULAR ACCIDENT0.7% 0%
DYSPHAGIA0.7% 0%
INJECTION SITE SWELLING0% 0.7%
TUBULOINTERSTITIAL NEPHRITIS0.7% 0%
HYPOAESTHESIA0.5% 0.6%
DRUG INTERACTION0.6% 0.5%
OSTEOARTHRITIS0.4% 0.6%
MYALGIA0.6% 0.4%
OROPHARYNGEAL PAIN0.4% 0.6%
HYPERSENSITIVITY0.4% 0.6%
DEHYDRATION0.6% 0%
PRODUCT USE ISSUE0.6% 0%
TREMOR0.6% 0%
SOMNOLENCE0.6% 0%
MULTIPLE FRACTURES0.6% 0%
FEBRILE NEUTROPENIA0% 0.6%
ARTHROPATHY0% 0.6%
HERPES ZOSTER0% 0.6%
SWELLING0% 0.6%
INFLUENZA0% 0.6%
MUSCULOSKELETAL PAIN0% 0.6%
NEUTROPENIA0% 0.6%
INJECTION SITE BRUISING0% 0.6%
HEPATIC ENZYME INCREASED0% 0.6%
PARAESTHESIA0.5% 0.5%
BLOOD PRESSURE INCREASED0.5% 0.5%
HYPOTENSION0.5% 0.5%
INCORRECT DOSE ADMINISTERED0.4% 0.5%
MOBILITY DECREASED0% 0.5%
FLATULENCE0.5% 0%
INJECTION SITE HAEMORRHAGE0% 0.5%
THROMBOCYTOPENIA0% 0.5%
CHRONIC OBSTRUCTIVE PULMONARY DISEASE0.5% 0%
INFUSION RELATED REACTION0% 0.5%
ASTHMA0.5% 0%
BLOOD GLUCOSE INCREASED0.5% 0%
CONFUSIONAL STATE0.5% 0%
CHEST DISCOMFORT0.5% 0%
ABDOMINAL DISTENSION0.5% 0%
STOMATITIS0% 0.5%
GASTRIC DISORDER0.5% 0%
MEMORY IMPAIRMENT0.5% 0%
CHILLS0% 0.4%
CONTUSION0% 0.4%
SYNOVITIS0% 0.4%
MUSCULAR WEAKNESS0% 0.4%
TOXICITY TO VARIOUS AGENTS0% 0.4%
INFLAMMATION0% 0.4%
CELLULITIS0% 0.4%
MUCOSAL INFLAMMATION0% 0.4%
URTICARIA0% 0.4%
PALPITATIONS0.4% 0%
THROAT IRRITATION0.4% 0%
BLOOD CHOLESTEROL INCREASED0.4% 0%
CARDIAC FAILURE CONGESTIVE0.4% 0%
RENAL FAILURE ACUTE0.4% 0%
ADVERSE EVENT0.4% 0%
DRY MOUTH0.4% 0%
ATRIAL FIBRILLATION0.4% 0%
HIATUS HERNIA0.4% 0%
HYPERHIDROSIS0.4% 0%
LOSS OF CONSCIOUSNESS0.4% 0%
GASTROINTESTINAL HAEMORRHAGE0.4% 0%
CARDIAC DISORDER0.4% 0%
HYPERCHLORHYDRIA0.4% 0%

New treatments are found every day. View current Nexium research studies and Methotrexate clinical trials


Top 5 Nexium Reported Side Effects

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Top 5 Methotrexate Reported Side Effects

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Patient Forum

Recent Comments and Reports

Both feet and legs swelled up after third day of 40 mg caps

Does anyone have abdominal pain from long term Nexium use?

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Has anyone experienced a reuction in the immune system to picking up cold and flue viruses. Since taking Nexium I am constantly catching every Every type of cold, sore throat or chest infection going around.

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

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High gloucose level?

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After long treatment with Nexium I got fibromyalgia. Do you thinsk Laprazol can be a solution or is it going to promote a similar side effect?

Can i take cartia with atacand and nexium at the same time

Does anyone have abdominal pain from long term Nexium use?

Feet skin tight and itchy some fluid retention - hot feet.Take Nexium and Imdur

Has anyone experienced a reuction in the immune system to picking up cold and flue viruses. Since taking Nexium I am constantly catching every Every type of cold, sore throat or chest infection going around.

Have taken coumadin for 9 years. Have started on Pradaxa 5 months ago. Extreme heart burn so MD has put me on Nexium which helps most of the time. Am considering going off Clinical Trials as heart burn can last an hour and needs 3 times normal dose o

Hi! Some years ago I took nexium for v. severe gerd, with haemorrhage. From the time I started it, suddenly my gastric system was totally upset, where it hadn't previously. Because I wasn't digesting properly, my immune system was affected, and hav

I am experiencing severe heartburn, even when taking Nexium twice a day and using antacids, such a Tums. Never have experienced this level of discomfort when taking a prescription medicine. Not sure in the long term I can continue with this drug. It

I am taking mexium 20 mg regularly for last 1.5 years. Recent blood test have shown high level of liver enzymes . I am a non drinker and have never had any jaundice or any immunisation of hepatitis. Nexium definately messed up my healthy liver

I had been taking Nexium for two years and when I had tests in hospital they found that my liver count was 999 where it should only be 41. They took me off it straight away and within two days it had dropped to half and after seven days with no Ne