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Promethazine and Methotrexate

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectPromethazineMethotrexate
NAUSEA4.9% 2.7%
DRUG INEFFECTIVE1.7% 4.6%
ARTHRALGIA1.2% 3.7%
INJECTION SITE PAIN0.5% 3.6%
PAIN3.3% 2.9%
VOMITING3.2% 1.7%
RHEUMATOID ARTHRITIS0% 2.9%
FATIGUE2.5% 2.6%
HEADACHE2.2% 2.5%
DIARRHOEA2.5% 1.8%
DYSPNOEA2.2% 1.7%
PYREXIA1.5% 2.2%
PAIN IN EXTREMITY1.2% 2.2%
ANXIETY2.2% 0.5%
PNEUMONIA1.4% 1.9%
DIZZINESS1.8% 1.2%
ASTHENIA1.7% 1.2%
DEPRESSION1.7% 0.6%
INJECTION SITE ERYTHEMA0% 1.7%
ABDOMINAL PAIN1.6% 1%
MALAISE1.4% 1.5%
FALL1.5% 1.2%
COUGH0.9% 1.5%
DEATH1.5% 0.6%
NASOPHARYNGITIS0% 1.4%
JOINT SWELLING0% 1.4%
BACK PAIN1.3% 1.1%
WEIGHT DECREASED1.3% 1%
CHEST PAIN1.3% 0.7%
INSOMNIA1.3% 0.5%
INJURY1.3% 0%
TOXICITY TO VARIOUS AGENTS1.3% 0%
RASH1% 1.2%
SINUSITIS0.6% 1.2%
COMPLETED SUICIDE1.2% 0%
DEHYDRATION1.2% 0%
HYPERTENSION1.1% 0.8%
ANAEMIA1.1% 0.8%
CONDITION AGGRAVATED0.7% 1.1%
DECREASED APPETITE1.1% 0.5%
CONSTIPATION1.1% 0%
URINARY TRACT INFECTION0.9% 1%
SEPSIS0.6% 1%
HYPOTENSION1% 0.6%
ABDOMINAL PAIN UPPER1% 0.6%
INJECTION SITE PRURITUS0% 1%
PSORIASIS0% 1%
DRUG ABUSE1% 0%
OEDEMA PERIPHERAL0.9% 0.8%
GAIT DISTURBANCE0.7% 0.9%
PRURITUS0.7% 0.9%
INJECTION SITE SWELLING0% 0.9%
INFECTION0% 0.9%
SOMNOLENCE0.9% 0%
DEEP VEIN THROMBOSIS0.9% 0%
TREMOR0.9% 0%
WEIGHT INCREASED0.8% 0.7%
OFF LABEL USE0.6% 0.8%
BRONCHITIS0.6% 0.8%
MUSCLE SPASMS0.8% 0.5%
ERYTHEMA0% 0.8%
INJECTION SITE REACTION0% 0.8%
ARTHRITIS0% 0.8%
MUSCULOSKELETAL STIFFNESS0% 0.8%
INJECTION SITE BRUISING0% 0.8%
CONFUSIONAL STATE0.8% 0%
CARDIAC ARREST0.8% 0%
CHOLECYSTITIS CHRONIC0.8% 0%
EMOTIONAL DISTRESS0.8% 0%
PULMONARY EMBOLISM0.8% 0%
HYPOAESTHESIA0.7% 0.7%
DRUG DOSE OMISSION0.6% 0.7%
FEELING ABNORMAL0.7% 0.6%
CARDIAC FAILURE CONGESTIVE0.7% 0%
MIGRAINE0.7% 0%
DIABETES MELLITUS0.7% 0%
HYPERHIDROSIS0.7% 0%
PERIPHERAL SWELLING0% 0.7%
PANCYTOPENIA0% 0.7%
ALOPECIA0% 0.7%
INCORRECT DOSE ADMINISTERED0% 0.7%
OROPHARYNGEAL PAIN0% 0.7%
LOSS OF CONSCIOUSNESS0.7% 0%
CHOLELITHIASIS0.7% 0%
GASTROOESOPHAGEAL REFLUX DISEASE0.7% 0%
DRUG INTERACTION0.6% 0.6%
PARAESTHESIA0.6% 0.6%
RENAL FAILURE0.6% 0.5%
MYOCARDIAL INFARCTION0.6% 0.5%
DRUG HYPERSENSITIVITY0.6% 0.5%
CARDIO-RESPIRATORY ARREST0.6% 0%
SYNCOPE0.6% 0%
GALLBLADDER DISORDER0.6% 0%
DYSPEPSIA0.6% 0%
INJECTION SITE HAEMORRHAGE0% 0.6%
CEREBROVASCULAR ACCIDENT0.6% 0%
NEUTROPENIA0% 0.6%
HYPERSENSITIVITY0% 0.6%
INFUSION RELATED REACTION0% 0.6%
HEPATIC ENZYME INCREASED0% 0.6%
INFLUENZA0% 0.6%
ARTHROPATHY0% 0.6%
FEBRILE NEUTROPENIA0% 0.6%
MUSCULOSKELETAL PAIN0% 0.6%
HERPES ZOSTER0% 0.6%
RENAL FAILURE ACUTE0.6% 0%
OVERDOSE0.6% 0%
CONTUSION0.5% 0.5%
CHILLS0.5% 0.5%
BLOOD PRESSURE INCREASED0.5% 0.5%
MYALGIA0.5% 0.4%
THROMBOCYTOPENIA0% 0.5%
OSTEOARTHRITIS0% 0.5%
MOBILITY DECREASED0% 0.5%
MEMORY IMPAIRMENT0.5% 0%
DRUG EFFECT DECREASED0% 0.5%
INJECTION SITE HAEMATOMA0% 0.5%
MUSCULAR WEAKNESS0% 0.5%
URTICARIA0% 0.5%
ABDOMINAL DISCOMFORT0% 0.5%
SWELLING0% 0.5%
RESPIRATORY FAILURE0% 0.5%
SUICIDE ATTEMPT0.5% 0%
CELLULITIS0% 0.5%
STOMATITIS0% 0.5%
CHRONIC OBSTRUCTIVE PULMONARY DISEASE0.5% 0%
ABDOMINAL DISTENSION0.5% 0%
ATRIAL FIBRILLATION0.5% 0%
VISION BLURRED0.5% 0%
CONVULSION0.5% 0%
RESPIRATORY ARREST0.5% 0%
HAEMOGLOBIN DECREASED0.5% 0%
OSTEOPOROSIS0.5% 0%
AGITATION0.5% 0%
NEUROPATHY PERIPHERAL0.5% 0%
POISONING0.5% 0%
DYSPHAGIA0.5% 0%
BLOOD GLUCOSE INCREASED0.5% 0%
PALPITATIONS0.5% 0%
ECONOMIC PROBLEM0.5% 0%
UPPER RESPIRATORY TRACT INFECTION0% 0.4%
INFLAMMATION0% 0.4%
MUCOSAL INFLAMMATION0% 0.4%
LOCAL SWELLING0% 0.4%
PLEURAL EFFUSION0% 0.4%

New treatments are found every day. View current Promethazine research studies and Methotrexate clinical trials


Top 5 Promethazine Reported Side Effects

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Top 5 Methotrexate Reported Side Effects

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Patient Forum

Recent Comments and Reports

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spo

I have been on methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is

I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause diss

I only took it for 21 days but in that time, it put me into a full panic attack that lasted almost 8 days after I went off the medication. I had mental confusion, could not speak properly (I knew what I wanted to say but the words would not come out

I was diagnosed with Rheumatoid Arthritis about 4 years ago when I was 13 or 14, they looked at me and said I had it, they didn't do any blood tests and when they did, nothing showed. But they started me on about 5 mg of Methotrexate, Prednisone, and

Im a 44yrs old female who took methotrexate for 2yrs with excellent results and no side effects but had to stop taking it when it started lowering my white cells.

My 27 years of MTX therapy have prevented physical deformity but caused me to have damage to my lungs. I am short of breath on any activity. MTX helped the pain somewhat but at the cost of my lungs? I was never told about this possibility nor told it

Painful cough after 2 days of 1st dose lasting-- to date-- 6 days

What did you have?

49 yo woman, regular medication Promethazine 50mg nocte for allergies. Commenced Mobic 15 mg 2/7 ago. Currently expereincing severe headaches, tiredness, blurred vision and sleep disturbance - eg vivid dreaming/ hallucinations. Are these k

I got a promethazine shot 4-5 weeks ago in my hip due to nausea and vomiting from a stomach virus. I now have a small lump-knot where I got the shot at and it is really sore still. I was told to massage it and put heat on it to make it go away but i