Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side Effect Promethazine Methotrexate
DRUG INEFFECTIVE 1.7% 5%
NAUSEA 4.9% 2.7%
ARTHRALGIA 1.2% 3.6%
INJECTION SITE PAIN 0.5% 3.4%
PAIN 3.3% 2.9%
VOMITING 3.2% 1.6%
RHEUMATOID ARTHRITIS 0% 3.1%
FATIGUE 2.5% 2.6%
DIARRHOEA 2.5% 1.8%
HEADACHE 2.3% 2.4%
DYSPNOEA 2.2% 1.6%
ANXIETY 2.2% 0.5%
PYREXIA 1.5% 2.1%
PAIN IN EXTREMITY 1.2% 2.1%
PNEUMONIA 1.5% 1.9%
DIZZINESS 1.7% 1.2%
ASTHENIA 1.7% 1.2%
DEPRESSION 1.7% 0.6%
MALAISE 1.5% 1.6%
ABDOMINAL PAIN 1.6% 0.9%
INJECTION SITE ERYTHEMA 0% 1.6%
FALL 1.5% 1.2%
DEATH 1.5% 0.6%
JOINT SWELLING 0% 1.5%
COUGH 0.9% 1.4%
TOXICITY TO VARIOUS AGENTS 1.4% 0%
BACK PAIN 1.3% 1.1%
WEIGHT DECREASED 1.3% 1%
RASH 1% 1.3%
INSOMNIA 1.3% 0.5%
NASOPHARYNGITIS 0% 1.3%
CONDITION AGGRAVATED 0.7% 1.2%
CHEST PAIN 1.2% 0.7%
INJURY 1.2% 0%
DEHYDRATION 1.2% 0%
COMPLETED SUICIDE 1.2% 0%
ANAEMIA 1.1% 0.8%
HYPERTENSION 1.1% 0.8%
SINUSITIS 0.6% 1.1%
DECREASED APPETITE 1.1% 0.5%
CONSTIPATION 1.1% 0%
URINARY TRACT INFECTION 0.9% 1%
HYPOTENSION 1% 0.6%
SEPSIS 0.5% 1%
INJECTION SITE PRURITUS 0% 1%
PSORIASIS 0% 1%
INFECTION 0% 1%
DRUG ABUSE 1% 0%
GAIT DISTURBANCE 0.7% 0.9%
OFF LABEL USE 0.7% 0.9%
OEDEMA PERIPHERAL 0.9% 0.7%
ABDOMINAL PAIN UPPER 0.9% 0.6%
SOMNOLENCE 0.9% 0%
INJECTION SITE SWELLING 0% 0.9%
TREMOR 0.9% 0%
WEIGHT INCREASED 0.8% 0.7%
DRUG DOSE OMISSION 0.7% 0.8%
PRURITUS 0.7% 0.8%
BRONCHITIS 0.6% 0.8%
MUSCLE SPASMS 0.8% 0.5%
INJECTION SITE BRUISING 0% 0.8%
ALOPECIA 0% 0.8%
DEEP VEIN THROMBOSIS 0.8% 0%
PERIPHERAL SWELLING 0% 0.8%
CONFUSIONAL STATE 0.8% 0%
MUSCULOSKELETAL STIFFNESS 0% 0.8%
PULMONARY EMBOLISM 0.8% 0%
ARTHRITIS 0% 0.8%
CHOLECYSTITIS CHRONIC 0.8% 0%
CARDIAC ARREST 0.8% 0%
HYPOAESTHESIA 0.7% 0.7%
DRUG HYPERSENSITIVITY 0.7% 0.6%
FEELING ABNORMAL 0.7% 0.6%
HYPERHIDROSIS 0.7% 0%
PANCYTOPENIA 0% 0.7%
GASTROOESOPHAGEAL REFLUX DISEASE 0.7% 0%
MIGRAINE 0.7% 0%
EMOTIONAL DISTRESS 0.7% 0%
DIABETES MELLITUS 0.7% 0%
OVERDOSE 0.7% 0%
INJECTION SITE REACTION 0% 0.7%
ERYTHEMA 0% 0.7%
PARAESTHESIA 0.6% 0.6%
DRUG INTERACTION 0.6% 0.6%
RENAL FAILURE 0.6% 0.5%
HYPERSENSITIVITY 0.5% 0.6%
MYOCARDIAL INFARCTION 0.6% 0.5%
MUSCULOSKELETAL PAIN 0% 0.6%
ARTHROPATHY 0% 0.6%
INJECTION SITE HAEMORRHAGE 0% 0.6%
NEUTROPENIA 0% 0.6%
INFUSION RELATED REACTION 0% 0.6%
INFLUENZA 0% 0.6%
OROPHARYNGEAL PAIN 0% 0.6%
FEBRILE NEUTROPENIA 0% 0.6%
HERPES ZOSTER 0% 0.6%
DRUG EFFECT DECREASED 0% 0.6%
INCORRECT DOSE ADMINISTERED 0% 0.6%
HEPATIC ENZYME INCREASED 0% 0.6%
MOBILITY DECREASED 0% 0.6%
SYNCOPE 0.6% 0%
CEREBROVASCULAR ACCIDENT 0.6% 0%
HAEMOGLOBIN DECREASED 0.6% 0%
CARDIO-RESPIRATORY ARREST 0.6% 0%
CHOLELITHIASIS 0.6% 0%
LOSS OF CONSCIOUSNESS 0.6% 0%
CARDIAC FAILURE CONGESTIVE 0.6% 0%
DYSPEPSIA 0.6% 0%
SUICIDE ATTEMPT 0.6% 0%
ABDOMINAL DISCOMFORT 0.5% 0.5%
BLOOD PRESSURE INCREASED 0.5% 0.5%
CHILLS 0.5% 0.5%
MYALGIA 0.5% 0.4%
THROMBOCYTOPENIA 0% 0.5%
DRUG INTOLERANCE 0% 0.5%
BLOOD GLUCOSE INCREASED 0.5% 0%
PALPITATIONS 0.5% 0%
OSTEOARTHRITIS 0% 0.5%
STOMATITIS 0% 0.5%
RESPIRATORY FAILURE 0% 0.5%
DRUG EFFECT INCOMPLETE 0% 0.5%
CELLULITIS 0% 0.5%
CONTUSION 0% 0.5%
OSTEOPOROSIS 0.5% 0%
SWELLING 0% 0.5%
ABDOMINAL DISTENSION 0.5% 0%
ATRIAL FIBRILLATION 0.5% 0%
RENAL FAILURE ACUTE 0.5% 0%
RESPIRATORY ARREST 0.5% 0%
DYSPHAGIA 0.5% 0%
CONVULSION 0.5% 0%
AGITATION 0.5% 0%
VISION BLURRED 0.5% 0%
GALLBLADDER DISORDER 0.5% 0%
CHRONIC OBSTRUCTIVE PULMONARY DISEASE 0.5% 0%
GASTROINTESTINAL HAEMORRHAGE 0.5% 0%
NEUROPATHY PERIPHERAL 0.5% 0%
MEMORY IMPAIRMENT 0.5% 0%
INFLAMMATION 0% 0.4%
LOCAL SWELLING 0% 0.4%
MUSCULAR WEAKNESS 0% 0.4%
URTICARIA 0% 0.4%
MUCOSAL INFLAMMATION 0% 0.4%
INJECTION SITE HAEMATOMA 0% 0.4%

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Patient Forum

Recent Comments and Reports

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

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What did you have?

49 yo woman, regular medication Promethazine 50mg nocte for allergies. Commenced Mobic 15 mg 2/7 ago. Currently expereincing severe headaches, tiredness, blurred vision and sleep disturbance - eg vivid dreaming/ hallucinations. Are these k

I got a promethazine shot 4-5 weeks ago in my hip due to nausea and vomiting from a stomach virus. I now have a small lump-knot where I got the shot at and it is really sore still. I was told to massage it and put heat on it to make it go away but i

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