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Zyrtec and Methotrexate

Compare Side Effects

% of total side effects reported by users. DISCLAIMER: ALL DATA PROVIDED AS-IS. Data Source: openfda.gov.
Side EffectZyrtecMethotrexate
DRUG INEFFECTIVE4.8% 7.4%
ARTHRALGIA1.4% 3.5%
RHEUMATOID ARTHRITIS0% 3.3%
FATIGUE3.2% 2.5%
NAUSEA3.1% 2.7%
PAIN2.3% 2.9%
HEADACHE2.9% 2.2%
OFF LABEL USE2.7% 1%
INJECTION SITE PAIN0.7% 2.7%
DYSPNOEA2.4% 1.5%
DIZZINESS2.2% 1.1%
PRURITUS2.2% 0.8%
DIARRHOEA2.1% 1.7%
PAIN IN EXTREMITY1.2% 2%
SOMNOLENCE2% 0%
PYREXIA1.2% 1.9%
VOMITING1.7% 1.6%
PNEUMONIA1% 1.7%
PRODUCT USE ISSUE1.7% 0%
RASH1.6% 1.3%
ANXIETY1.6% 0.4%
JOINT SWELLING0% 1.6%
MALAISE1.5% 1.5%
INSOMNIA1.5% 0.5%
COUGH1.4% 1.3%
URTICARIA1.4% 0.4%
CONDITION AGGRAVATED0.9% 1.3%
DEPRESSION1.3% 0.6%
DRUG HYPERSENSITIVITY0.6% 1.3%
FEELING ABNORMAL1.3% 0.5%
INJECTION SITE ERYTHEMA0.4% 1.3%
THERAPEUTIC RESPONSE UNEXPECTED1.3% 0%
ASTHENIA1.2% 1.1%
NASOPHARYNGITIS0.6% 1.2%
HYPERSENSITIVITY1.2% 0.6%
FALL1.1% 1.1%
SINUSITIS1.1% 1%
DRUG INTOLERANCE0% 1.1%
PRODUCT QUALITY ISSUE1.1% 0%
WEIGHT DECREASED1% 1%
BACK PAIN1% 1%
WEIGHT INCREASED1% 0.7%
ALOPECIA0.7% 1%
PSORIASIS0% 1%
INFECTION0% 1%
ABDOMINAL PAIN0.9% 0.9%
HYPERTENSION0.9% 0.8%
URINARY TRACT INFECTION0.7% 0.9%
ABDOMINAL PAIN UPPER0.9% 0.6%
CHEST PAIN0.9% 0.6%
DRUG EFFECT INCOMPLETE0.5% 0.9%
INCORRECT DOSE ADMINISTERED0.9% 0.5%
PERIPHERAL SWELLING0.4% 0.9%
SEPSIS0% 0.9%
PRODUCT USE IN UNAPPROVED INDICATION0.9% 0%
MUSCULOSKELETAL STIFFNESS0% 0.9%
ASTHMA0.9% 0%
DRUG DOSE OMISSION0.8% 0.7%
GAIT DISTURBANCE0.6% 0.8%
ERYTHEMA0.8% 0.6%
PARAESTHESIA0.8% 0.5%
MUSCLE SPASMS0.8% 0.4%
CONSTIPATION0.8% 0%
DRUG EFFECT DECREASED0% 0.8%
ARTHRITIS0% 0.8%
INJECTION SITE PRURITUS0% 0.8%
TREATMENT FAILURE0% 0.8%
ABDOMINAL DISCOMFORT0.7% 0.7%
HYPOAESTHESIA0.7% 0.6%
OEDEMA PERIPHERAL0.7% 0.6%
BRONCHITIS0.6% 0.7%
ANAEMIA0.5% 0.7%
DECREASED APPETITE0.7% 0.5%
OVERDOSE0.7% 0%
INJECTION SITE SWELLING0% 0.7%
PANCYTOPENIA0% 0.7%
MYALGIA0.7% 0%
TREMOR0.7% 0%
INJECTION SITE REACTION0% 0.7%
BLOOD PRESSURE INCREASED0.6% 0.5%
GASTROOESOPHAGEAL REFLUX DISEASE0.6% 0%
FLUSHING0.6% 0%
OSTEOARTHRITIS0% 0.6%
DRUG INEFFECTIVE FOR UNAPPROVED INDICATION0.6% 0%
HERPES ZOSTER0% 0.6%
DEHYDRATION0.6% 0%
SWELLING0% 0.6%
VISION BLURRED0.6% 0%
MIGRAINE0.6% 0%
INFLUENZA0% 0.6%
PALPITATIONS0.6% 0%
FEBRILE NEUTROPENIA0% 0.6%
NEUTROPENIA0% 0.6%
ARTHROPATHY0% 0.6%
INJECTION SITE BRUISING0% 0.6%
HEPATIC ENZYME INCREASED0% 0.6%
MUSCULOSKELETAL PAIN0% 0.6%
CHEST DISCOMFORT0.6% 0%
HYPOTENSION0.5% 0.5%
OROPHARYNGEAL PAIN0.5% 0.5%
CONTUSION0.5% 0.4%
CHILLS0.5% 0.4%
HYPERHIDROSIS0.5% 0%
INJURY0.5% 0%
MEMORY IMPAIRMENT0.5% 0%
BLOOD GLUCOSE INCREASED0.5% 0%
DEEP VEIN THROMBOSIS0.5% 0%
CONFUSIONAL STATE0.5% 0%
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS0.5% 0%
PULMONARY EMBOLISM0.5% 0%
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION0.5% 0%
DRY MOUTH0.5% 0%
DYSGEUSIA0.5% 0%
DYSPEPSIA0.5% 0%
MUCOSAL INFLAMMATION0% 0.5%
DEATH0% 0.5%
STOMATITIS0% 0.5%
INFUSION RELATED REACTION0% 0.5%
MOBILITY DECREASED0% 0.5%
HEART RATE INCREASED0.5% 0%
THROMBOCYTOPENIA0% 0.5%
INJECTION SITE HAEMORRHAGE0% 0.5%
DRUG INTERACTION0% 0.5%
MUSCULAR WEAKNESS0.4% 0.4%
MYOCARDIAL INFARCTION0% 0.4%
PSORIATIC ARTHROPATHY0% 0.4%
INFLAMMATION0% 0.4%
TOXICITY TO VARIOUS AGENTS0% 0.4%
CELLULITIS0% 0.4%
RENAL FAILURE0% 0.4%
SYNOVITIS0% 0.4%
DYSPHAGIA0.4% 0%
EXPIRED PRODUCT ADMINISTERED0.4% 0%
LOSS OF CONSCIOUSNESS0.4% 0%
WHEEZING0.4% 0%
ABDOMINAL DISTENSION0.4% 0%
DRUG ADMINISTERED TO PATIENT OF INAPPROPRIATE AGE0.4% 0%
CEREBROVASCULAR ACCIDENT0.4% 0%
RHINORRHOEA0.4% 0%

New treatments are found every day. View current Zyrtec research studies and Methotrexate clinical trials


Top 5 Zyrtec Reported Side Effects

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Top 5 Methotrexate Reported Side Effects

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Patient Forum

Recent Comments and Reports

Bad gastritis or abdominal pain; had to get into tub with hot shower on my belly;never had a worse experience or pain; thought I was going to die; malaise; moderate ear pain

Does Zyrtec inrease blood sugar levels? I have been taking 10m a day for 10 days and have notices symptoms of high blood sugar, when tested it was in the high 100's. Has anyone heard of this side effect?

Have you had him checked for P.A.N.D.A.S which is a syndrome related to strep throat. One major symptom can be sudden onset of Tourette's. ALso can cause OCD, depression, and other psychiatric conditions. My son has it. SOme doctors don't believe in

Hi I haven't had any side effects for the past six years of Methotrexate. but recently I am having some stomach discomfort like as soon as i eat something i have the slight discomfort on my abdoman. I take a glass of green leaf juice and i am fine ag

I am 60 Years of age. 8 years ago i was falsely diagnosed with Rheumatoid Arthritis, i was started on Methoblastin 5Mg a week, Was not given Folic Acid and Ranitidine within the 5 months of taking the tablets i developed exposed blood vessels and spo

I have a 12 year old son who took Zyrtec for year-round allergies. He now has tourettes syndrome and westrongly feelthe Zyrtec played a role in this health issue. I started searching the web for info regarding

I have been on methotrexate for almost months and last two weeks have had severe pains at times lower back , It feel like the kidneys because one side hurts at times and in the mornings it is worse. I am 3 days shy of talking another blood test. Is

I have had and am having a bad reaction to Zyrtec. My eyes are inflamed and my throat is sore. Lips are swollen. My tongue is white. I will be forced to go to the Emergency at the hospital.

I have Type 2 Diabetes, when taking my level in the morning I noticed my level was elevated, and the only thing I had ingested was a Zyrtec pill about 2 hours prior? Could the pill be the cause?

I just started Methotrexate, I started itching in the same areas where I had experienced itching with the chicken pox 2 years ago. I am a 51 year old female who contracted chicken pox at 49 years old. This frightens me as I know this can cause diss

I only took it for 21 days but in that time, it put me into a full panic attack that lasted almost 8 days after I went off the medication. I had mental confusion, could not speak properly (I knew what I wanted to say but the words would not come out

I took one dose and experienced a bout of pancreatitis. I suffer from chronic pancreatitis and know what most of my 'triggers' are.....never thought a simple allergy medication would cause such a problem, I think I would rather suffer allergies than

Does anyone know if taking large amounts of Zyrtec and Xyzal cause viral infections in the Sinuses or throat? Thanks Carmalite

Does Zyrtec inrease blood sugar levels? I have been taking 10m a day for 10 days and have notices symptoms of high blood sugar, when tested it was in the high 100's. Has anyone heard of this side effect?

I have a 12 year old son who took Zyrtec for year-round allergies. He now has tourettes syndrome and westrongly feelthe Zyrtec played a role in this health issue. I started searching the web for info regarding

I have had and am having a bad reaction to Zyrtec. My eyes are inflamed and my throat is sore. Lips are swollen. My tongue is white. I will be forced to go to the Emergency at the hospital.

I have Type 2 Diabetes, when taking my level in the morning I noticed my level was elevated, and the only thing I had ingested was a Zyrtec pill about 2 hours prior? Could the pill be the cause?

I took Zyrtec for a week and while it does solve my allergy issues, it makes me a raving lunatic. Severe aggression, mood swings, and nightmares are the norm for me n this medicine. I would not recommend it if you are taking any a

Started on Zyrtec on the suggestion of my dermatologist for treatment of hives. Rash that resulted from the Zyrtec a MILLION times worse than the original hives. Had the same reaction to Seldane.