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Aclovate Ointment Medical Research Studies

Up-to-date List of Aclovate Ointment Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Aclovate Ointment Medical Research Studies

Rank Status Study
1 Recruiting Development of a Milk Product Substitution for Patients Suffering From Xerostomia Caused by Medication
Condition: Xerostomia
Interventions: Other: LactoXeros;   Device: Aequasyal
Outcome Measures: Mouth Dryness Score;   Perception of other symptoms of dry mouth;   Silness-Loe Index measuring dental plaque;   Salivary flow;   Biochemical analysis of saliva;   Analysis of the mouth coating effect;   Release of the aroma compounds
2 Recruiting Treatment of Xerostomia by Herbal Preparation
Condition: Xerostomia
Interventions: Dietary Supplement: Herbal extract granule;   Dietary Supplement: Placebo herbal extract granule
Outcome Measures: Visual Analogue Scale (VAS) for xerostomia;   Unstimulated Salivary Flow Rate (USFR) and Stimulated salivary flow rate (SSFR);   Residual saliva;   Salivary IgA, Chromogranin A, Cortisol;   Dry Mouth Symptom Questionnaire(DMSQ)
3 Unknown  Drug-induced Xerostomia. Evaluation of Malic Acid 1%, Salivary Mucins and Buffering Capacity
Conditions: Xerostomia;   Depression;   Hypertension
Interventions: Drug: Malic Acid;   Other: Placebo
Outcome Measures: Dry mouth questionnaire (DMQ);   Sialometries
4 Unknown  Green Tea Lozenges for the Management of Dry Mouth
Conditions: Xerostomia;   Sjogren Syndrome;   Dry Mouth
Intervention: Dietary Supplement: Green tea lozenge
Outcome Measure: Improvement in salivary flow from baseline
5 Unknown  Lipid Based Food Additives for Treating Patients With Dry Mouth
Condition: Xerostomia
Intervention: Device: lipid based additives based on vegetable oil & lecithin
Outcome Measure: Improvement in dry mouth symptom
6 Unknown  Hyperbaric Oxygen for the Treatment of a Dry Mouth Which Occurred After Radiotherapy
Condition: Radiation-Induced Xerostomia
Intervention: Drug: oxygen
Outcome Measures: change of overall salivation (millilitre per minute over 5 minutes measured at rest and after provocation) in percentages;   toxicity;   xerostomia scores;   improvement of symptoms measured on a visual analogue scale;   quality of life measures (EORTC QLQ-H&N 35)
7 Recruiting Acupuncture in Treating Dry Mouth Caused By Radiation Therapy in Patients With Head and Neck Cancer
Conditions: Head and Neck Cancer;   Long-term Effects Secondary to Cancer Therapy in Adults;   Oral Complications of Chemotherapy and Head/Neck Radiation;   Radiation Toxicity;   Xerostomia
Intervention: Procedure: Acupuncture
Outcome Measures: Response to acupuncture intervention;   Duration of response to a maximum of 6 months
8 Recruiting Xerostomia Acupuncture Trial
Condition: Head And Neck Cancer
Interventions: Procedure: Acupuncture - Group 1;   Procedure: Acupuncture - Group 2;   Other: Standard Care;   Other: Questionnaire
Outcome Measure: Self-Reported Xerostomia Symptoms Using the Xerostomia Questionnaire (XQ)
9 Unknown  Hypnosis for Treating Xerostomia Following Radiotherapy in Head & Neck Cancer Patients
Condition: Xerostomia
Intervention: Behavioral: hypnosis
Outcome Measures: salivaa volume;   quality of life related to salivation
10 Recruiting Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome
Conditions: KERATOCONJUNCTIVITIS SICCA;   XEROSTOMIA;   SICCA SYNDROME;   PRIMARY SJOGREN SYNDROME
Interventions: Device: Laser 3R 790nm infrared Ga AIAs;   Device: Laser 3R 790 nm infrared  GaAIAs
Outcome Measures: The xerostomia inventory;   salivary  analysis by proteomic;   Salivary flux measurement
11 Unknown  Rebamipide for the Treatment of Xerostomia in sjögren Syndrome
Condition: Improving Symptoms of Dry Mouth in Sjőgren's Syndrome
Intervention: Drug: Rebamipide
Outcome Measure: improvement of dry mouth symptoms
12 Recruiting NeutraSal Treatment for Xerostomia in OSAS Patients Using CPAP Therapy
Condition: Xerostomia
Interventions: Drug: NeutraSal;   Drug: Placebo (for NeutraSal)
Outcome Measures: Impact of NeutraSal on OSAS patients;   Prevention or reduction of Dry Mouth with NeutraSal
13 Recruiting Neurological Effects of Acupuncture
Condition: Head and Neck Cancer
Interventions: Behavioral: Questionnaires;   Procedure: Acupuncture;   Procedure: Electroencephalogram (EEG)
Outcome Measures: Relative Changes of EEG Scores Between Pre- and Post-Acupuncture;   Symptoms of Xerostomia
14 Recruiting Adaptative Radiotherapy to Decrease Xerostomia in Oropharynx Carcinoma
Condition: Oropharynx Cancer
Intervention: Radiation: adaptative radiotherapy
Outcome Measures: Salivary flow measure;   Xerostomia;   Salivary flow;   Local control;   Early and late toxicities;   Survival;   Head and Neck functionality
15 Recruiting Dexamethasone Irrigation of the Parotid Glands in Primary Sj(SqrRoot)(Delta)Gren s Syndrome Subjects
Conditions: Sj(SqrRoot)(Delta)Gren s Syndrome;   Xerostomia
Intervention: Drug: Dexamethasone
Outcome Measures: Change in salivary flow from Day 0 to Day 56.;   Change in focus score on biopsy.;   Change in salivary flow from Day 0 to study Days 14, 28, 42 and 56.;   Change in responses on Patient Dry Mouth Questionnaire.;   Change in other assessments of salivary function.;   Change in laboratory measures of inflammation.;   Change in frequency of AEs.
16 Recruiting Photon/Proton Radiation Therapy for Cancers of the Nasal Cavity and/or Paranasal Sinuses
Conditions: Cancers of Nasal Cavity;   Cancers of Paranasal Sinuses
Intervention: Other: Xerostomia questionnaire
Outcome Measures: Grade 3 or higher of xerostomia Incidence of Xerostomia;   Collect and analyze tumor control outcomes
17 Recruiting Evaluation of Salivary Gland Dysfunction
Conditions: Sjogren's Syndrome;   Xerostomia
Intervention:
Outcome Measure:
18 Unknown  Treatment of Salivary Gland Hypofunction With Neuro- Electrostimulation
Conditions: Xerostomia;   Polypharmacy;   Sjögren's Syndrome
Interventions: Device: Automatic neuro-electrostimulation by "Saliwell Crown";   Device: Patient-regulated neuro-electrostimulation by "Saliwell Crown"
Outcome Measure: self-reported xerostomia
19 Recruiting Evaluation of Treatment Related Toxicity After Radiotherapy for Head and Neck Cancer
Conditions: Head and Neck Neoplasms;   Xerostomia;   Deglutition Disorders
Intervention:
Outcome Measure: toxicity
20 Unknown  Evaluation of Safety and Efficacy of Using Lipsus Device for Oral Wetting
Conditions: Oral Dryness;   General Surgery
Intervention: Device: wetting lips following surgery using anesthesia
Outcome Measures: The safety of using the Lipsus device for oral wetting will be established by physician's assessment/observation of adverse events (signs of pain, allergies, infection or any adverse effect).;   The efficacy of using the Lipsus device for oral wetting will be established by Level of oral dryness improvement measured by VAS oral dryness questionnaire.

These studies may lead to new treatments and are adding insight into Aclovate Ointment etiology and treatment.

A major focus of Aclovate Ointment research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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