Up-to-date List of Acne Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Acne Medical Research Studies

1 Recruiting Evaluation of the Role of Propionibacterium ACNEs in the Inflammatory Lesions Associated With ACNE Vulgaris
Condition: ACNE
Interventions: Procedure: Skin biopsy;   Procedure: Blood draw
Outcome Measures: Inflammatory markers;   P. ACNEs antibody levels
2 Recruiting Ultherapy® for the Treatment of ACNE Scars
Conditions: ACNE Scars;   Atrophic ACNE Scars
Intervention: Device: Ultherapy® treatment
Outcome Measures: ACNE Scar Improvement Scale;   Physician Scar Improvement Scale (PSIS) and Self-Assessed Scar Improvement Scale (SASIS);   Physician ACNE Scar Assessment Scale;   Clinician Global Aesthetic Improvement Scale (CGAIS) and Subject Global Aesthetic Improvement Scale (SGAIS);   Patient Satisfaction Questionnaire (PSQ)
3 Unknown  A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial ACNE
Condition: ACNE Vulgaris
Interventions: Drug: clindamycin phosphate 1.2%/tretinoin 0.025% gel alone;   Drug: clindamycin phosphate 1.2%/tretinoin 0.025% gel plus benzoyl peroxide 6% foaming cloths
Outcome Measures: Change in PGA scores of patients using combination clindamycin phosphate 1.2%/tretinoin 0.025% gel with or without benzoyl peroxide 6% foaming cloths for facial ACNE;   Change in Postinflammatory hyperpigmentation score at each study visit and from baseline to final visit.;   Total number of adverse events.;   Change in Subject Self Assessment Scoring Scale;   Change in ACNE-Specific Quality of Life Questionnaire (ACNE-QoL)
4 Recruiting Attitudes and Knowledge of ACNE in Mexican Adolescents
Condition: ACNE
Intervention: Behavioral: Survey
Outcome Measures: Cause for not receiving medical treatment;   Description of knowledge about ACNE;   Treatments for ACNE used by teenagers;   Professional indicated to treat ACNE
5 Unknown  Safety and Efficacy of Skin Cleanser Contained Roselle Extract in ACNE
Condition: ACNE
Interventions: Other: skin cleanser contained Hibiscus sabdariffa extract;   Other: marketed skin cleanser
Outcome Measures: 1. Safety evaluation: Patch test 2. Efficacy evaluation: ACNE lesions counts/ ACNE severity grading;   1. Safety evaluation: "a." Skin properties by visual and tactile features., "b." Biophysical parameters of skin. 2.Efficacy evaluation: Patient assessments.
6 Not yet recruiting The Efficacy and Safety of 3% Povidone-Iodine in ACNE Therapy
Condition: ACNE
Intervention: Drug: Repigel
Outcome Measures: 5 point ACNE Score;   Lesional Counts;   Effect on Quality of Life;   Safety
7 Recruiting A Five Day Clinical Study to Examine the Effects of a Benzoyl Peroxide Treatment on Facial ACNE Lesions
Condition: ACNE Vulgaris
Interventions: Drug: 3% Benzoyl Peroxide;   Drug: Neutrogena Rapid Clear;   Drug: 3% Benzoyl Peroxide Placebo
Outcome Measures: To assess the change in ACNE lesion swelling (height) for the 3% benzoyl peroxide gel test article relative to the vehicle gel after 4 once-daily applications.;   To assess the change in ACNE lesion swelling (height) for the 3% benzoyl peroxide gel test article relative to the vehicle gel at other evaluations
8 Unknown  Study Assessing the Effect of Chocolate Consumption in Subjects With A History of ACNE Vulgaris
Condition: ACNE
Interventions: Dietary Supplement: 100% cocoa powder;   Dietary Supplement: gelatin (Gelita)
Outcome Measure: development of ACNEiform lesions
9 Unknown  the Comparison Efficacy of Azithromycin With Doxycycline in the Treatment of ACNE Vulgaris
Condition: ACNE
Interventions: Drug: Doxycycline;   Drug: Azithromycin
Outcome Measures: change in ACNE lesions;   global response rates, patient's own assessment, side effects and compliance
10 Recruiting An Open, Non-comparative Study of the Efficacy and Safety of Treatment of ACNE Scars With Restylane Vital Lidocaine
Condition: ACNE Scars
Intervention: Device: Restylane Vital Lidocaine
Outcome Measures: Evaluation of ACNE scarring and the surrounding skin using the Global Aesthetic Improvement Scale;   Evaluation of skin quality and overall satisfaction using a Subject Satisfaction Questionnaire;   Evaluation of ACNE scarring using the Scale for ACNE Scar Severity;   Assessment of local tolerability after treatment;   Adverse Event reporting during the study
11 Recruiting Identifying the Genetic Predictors of Severe ACNE Vulgaris and the Outcome of Oral Isotretinoin Treatment
Conditions: ACNE Vulgaris;   Isotretinoin
Outcome Measures: Therapeutic response to isotretinoin;   Adverse reaccion to isotretinoin
12 Recruiting Pilot Study to Evaluate Tea Tree Oil Gel for Facial ACNE
Condition: ACNE
Intervention: Other: Tea tree oil
Outcome Measures: Lesion numbers;   Investigator Global Assessment;   Decreased non-inflammatory lesion count;   Decreased inflammatory lesion count;   Decrease in perceived facial oiliness
13 Unknown  Safety and Efficacy Study of Acnase Creme in the Treatment of ACNE Vulgaris I and II
Condition: ACNE Vulgaris
Interventions: Drug: Benzoyl Peroxide 5% and Sulphur 2%;   Drug: Vehicle of Acnase
Outcome Measures: Average clinical development of target lesions of the groups for each experimental time.;   Clinical evolution of the ACNE through the counting of inflammatory and non - inflammatory lesions.;   Evaluation of oily skin through the clinical evaluation with four-point scale (absent, mild, moderate, intense);   Observation of occurrence and intensity of clinical parameters erythema, scaling, itching and burning through the clinical evaluation with four-point scale (absent, mild, moderate, severe).
14 Recruiting Comparison Between Interactive Internet-based Education and Counseling for the Management of ACNE With That of Internet-based Education Alone
Condition: ACNE Vulgaris
Intervention: Behavioral: Virtual Counseling
Outcome Measures: ACNE Lesion Counts (Inflammatory and Non-inflammatory);   Dermatology Life Quality Index
15 Not yet recruiting The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of ACNE Scars
Condition: ACNE Scars
Intervention: Drug: 70% glycolic acid
Outcome Measures: Efficacy Assessment;   Safety Assessment
16 Unknown  A Study to Evaluate the Efficacy of Silk - Like Bedding Fabric, as Used in a Standard Pillow Case, in the Treatment of ACNE Vulgaris
Condition: ACNE Vulgaris
Interventions: Device: silk-like fabric standard pillowcase;   Device: pillowcase made of 100% cotton
Outcome Measures: The primary outcome is Investigator Global Assessment of Improvement measuring reduction in inflammatory lesions from Baseline to Week 12.;   The secondary outcome is patient assessment of facial ACNE vulgaris assessment.
17 Unknown  "A Randomized, Controlled, Evaluator-blinded Pilot Study to Evaluate the Effect of Automated Text Message Reminders on Patient Compliance With Topical Medications and Its Efficacy on Skin Disease Control in Adolescents and Adults With Mild to Moderate ACNE"
Conditions: ACNE;   Patient Compliance
Intervention: Other: Text message reminders
Outcome Measures: adherence to topical medication use;   Improvement in ACNE severity (as measured by IGA score)
18 Recruiting Comparison of the Efficacy and Safety of Clindamycin + Benzoyl Peroxide Formulation With Azelaic Acid Formulation in the Treatment of ACNE Vulgaris
Condition: ACNE Vulgaris
Interventions: Drug: Clindamycin + BPO;   Drug: Azelaic acid
Outcome Measures: Change from Baseline of inflammatory lesion counts at Week 4;   Change from Baseline of lesion counts;   Change from Baseline of lesions by Investigator's Static Global Assessment (ISGA);   Time to 50% reduction in total lesion count;   Change from Baseline of local tolerability as assessed by investigator;   Subject's global change assessment (SGCA) of skin;   Change from Baseline of local tolerability as assessed by subject;   Subject satisfaction score at Week 12;   Measured adherence to study medication at Week 12;   Quality of Life Assessments;   Number of treatment related adverse events (AEs) and serious adverse events (SAEs)
19 Unknown  Open and Comparative Study to Measure Tolerability and Efficacy of Taro Elixir
Conditions: ACNE Vulgaris II or III Degree; Boils
Interventions: Drug: oxytetracycline, taro elixir;   Drug: Taro Elixir
Outcome Measures: Measure the efficacy in the treatment of boils or ACNE vulgaris II and III degree with taro elixir compared with Oxytetracycline.;   Measure the tolerability in the treatment evolution of boils or ACNE vulgaris II and III with taro elixir compare with Oxytetracycline.
20 Unknown  Safety and Efficacy Comparison of Minocycline Microgranules Versus Lymecycline in the Treatment of Mild to Moderate ACNE
Condition: Mild to Moderate ACNE
Intervention: Drug: Minocycline vs Lymecycline
Outcome Measures: Number of inflammatory and non-inflammatory ACNE lesions;   Incidence of local and systemic adverse events

These studies may lead to new treatments and are adding insight into Acne etiology and treatment.

A major focus of Acne research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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