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Acupan Medical Research Studies

Up-to-date List of Acupan Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Acupan Medical Research Studies

Rank Status Study
1 Recruiting The Analgesic Effect of Nefopam on the Fentanyl Based PCA (Patient-controlled Analgesia) After Lumbar Spinal Surgery
Condition: Lumbar Spinal Stenisis or Lumbar Herniated Intervertebral Disc
Intervention: Drug: nefopam
Outcome Measure: The additional analgesic effect of nefopam on the fentanyl based PCA after lumbar spinal surgery
2 Recruiting Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric Colic
Condition: Renal Colic
Interventions: Drug: Ketorolac and nefopam balanced analgesia;   Drug: Balanced analgesia using ketorolac and morphine;   Drug: Pain control with single analgesics (ketorolac)
Outcome Measures: Amount of pain reduction by visual analog pain scale;   Additional analgesia requested by enrolled patients
3 Recruiting Effect of Nefopam on Acute Postoperative Pain in Patients Undergoing Orthognathic Surgery
Conditions: Pain;   Orthognathic Surgery
Interventions: Drug: nefopam;   Drug: normal saline (control)
Outcome Measure: pain score on the visual analogue scale
4 Recruiting Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.
Condition: Post Operative Analgesia
Interventions: Drug: Paracetamol;   Drug: Nefopam;   Drug: Ketoprofen;   Drug: Morphine
Outcome Measures: Morphine consumption (mg), accumulated over 24 hours, measured by patient controlled analgesia (PCA).;   Morphine consumption (mg) measured by patient controlled analgesia (PCA).;   Incidence of side effects associated with morphine: nausea, vomiting, sedation, urinary retention, pruritus.;   Area of hyperalgesia measured using a von Frey filament expressed in cm2, 48 hours after surgery (sub-study in 3 centers).;   Incidence of chronic pain assessed by a telephone questionnaire 3 months after surgery (sub-study in 3 centers).;   Global satisfaction (measured after treatment)
5 Recruiting Prospective Randomized Trial Comparing the Effectiveness of Continuous Paravertebral Infusion of Local Anesthetics Versus Intravenous Patient-controlled Analgesia on Acute and Chronic Neuropathic Pain After VATS Lobectomy
Conditions: Lung Cancer,;   Postoperative Pain
Interventions: Drug: 0.5% ropivacaine;   Drug: Fentanyl 500mcg + Acupan 160mg + nasea 0.6mg
Outcome Measures: 1. Acute pain;   2. Quality of life
6 Recruiting Epidural Analgesia for Pancreatitis (Epipan Study)
Condition: Severe Acute Pancreatitis
Interventions: Other: ropivacaine and sufentanil;   Other: acetaminophen, nefopam, tramadol, opidoids
Outcome Measures: Ventilator-free days;   Duration of invasive and/or non invasive mechanical ventilation;   incidence of various complications;   Biological inflammatory response;   Cost analysis of severe AP management;   Incidence of the intolerance to enteral feeding;   Effectiveness of pain management;   Duration of EA (Epidural anesthesia) therapy
7 Recruiting Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After Thoracotomy
Conditions: Pain;   Thoracotomy
Interventions: Drug: ropivacaine 0.75% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun);   Drug: Placebo;   Drug: ropivacaine 0.2% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun)
Outcome Measure: Total intravenous morphine consumption (mg)

These studies may lead to new treatments and are adding insight into Acupan etiology and treatment.

A major focus of Acupan research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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