Up-to-date List of Alopecia Medical Research Studies
What Research is Being Done?
A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.
Device: 308-nm excimer laser to Alopecia patch; Device: Liquid light guide tip on laser
The goal of this study is to assess the feasibility, safety and response to treatment of the use of the 308-nm excimer laser in children diagnosed with patch type Alopecia areata involving the scalp, present for more than 6 months duration; Evaluate the feasibility and safety of twice-weekly excimer laser treatments over a period of 12 weeks
Change in SALT Score; Change in Percentage of Hair Loss; Change in Patient Global Assessment; Change in Physician Global Assessment (PGA) Score; Patient Quality of Life Assessment Score; Incidence of Adverse Effects
Change in the percentage of hair regrowth for each half. We will consider the treamtment successful if there was ≥50% hair regrowth from baseline.; Change in hair count and caliber in each half; Assessment of side effects in each half
Proportion of subjects with a change in sexual function defined as a negative change from baseline in the IIEF-EF score of >=4 units or a score of <=25 on or before Week 24; Proportion of subjects with a negative change from baseline in the IIEF-EF score of >=4 units or a score of <=25 on or before Weeks 4 and 12 as well as the Follow-up Visit; Change from baseline in total score of the IIEF at Weeks 4, 12, and 24 as well as the Follow-up Visit; Change from baseline in the individual domain scores: erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall sexual satisfaction, of the IIEF at Weeks 4, 12 and 24 as well as the Follow-up Visit; Change from baseline in subject satisfaction with hair growth as assessed by the total score of the Hair Growth Satisfaction Scale (HGSS) at Weeks 12 and 24; Change from baseline in the total score of the Dermatology Life Quality Index (DLQI) at Weeks 12 and 24; Occurrence of adverse events related to sexual dysfunction
Severity of Alopecia Tool (SALT); Comparison of Tamoxifen, AI or Tamoxifen plus AI
These studies may lead to new treatments and are adding insight into Alopecia etiology and treatment.
A major focus of Alopecia research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.