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Ampicillin Medical Research Studies

Up-to-date List of Ampicillin Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Ampicillin Medical Research Studies

Rank Status Study
1 Recruiting Ampicillin for DYT-1 Dystonia Motor Symptoms
Conditions: DYT-1;   Dystonia
Interventions: Drug: Ampicillin;   Drug: Sugar pill
Outcome Measures: Safety and tolerability of Ampicillin in treating DYT-1 dystonia;   Burke-Fahn Marsden Dystonia Rating Scale (BFM-DRS)
2 Recruiting Concentration of Ampicillin / Sulbactam and Amoxicillin / Clavulanic Acid in the Blood During Renal Replacement Therapy in Longterm Renal Replacement Therapy Patients
Condition: Infection During Hemodialysis
Interventions: Drug: Administration of Amoxicillin / clavulanic acid;   Drug: Ampicillin / sulbactam;   Procedure: Blooddraws for pharmacokinetic profiling
Outcome Measure: Influence of hemodialysis on the area under concentration curve of Ampicillin/sulbactam and amoxicillin / clavulanic acid plasma concentration levels.
3 Unknown  Study to Proof the Clinical and Bacteriological Non-inferiority of Ampicillin/Amoxicillin Versus Moxifloxacin in Hospitalized Patients With Non-severe Community-acquired Pneumonia
Condition: Community Acquired Pneumonia
Interventions: Drug: Moxifloxacin;   Drug: Ampicillin;Amoxicillin
Outcome Measures: Proof of the clinical non inferiority by the cure rate at the treatment of a Pneumonia at the therapy end (round 3: Day 7 to 10) with a standard penicillin in a high dosage;   clinical cure rate;   bacteriological effectiveness on patients and seed level;   bacteriological sensitivity into-vitro;   time up to the drug-switch;   time until the dismissal of the patients necessity of the gift of additional antibacterial drug;   cost reduction of the antibiotic-therapy and the complete treatment;   assessment of the effectiveness by the investigator
4 Recruiting Antibiotic Safety (SCAMP)
Condition: Complicated Intra Abdominal Infections
Interventions: Drug: Ampicillin and metronidazole and gentamicin;   Drug: Ampicillin and gentamicin and clindamycin;   Drug: gentamicin and Piperacillin- tazobactam;   Drug: standard of care antibiotics and metronidazole
Outcome Measures: Death;   Number of participants with therapeutic success at Day 30 and Day 90
5 Unknown  Treatment of Chorioamnionitis After Delivery
Condition: Chorioamnionitis
Interventions: Drug: saline;   Drug: Ampicillin gentamicin;   Drug: Ampicillin gentamicin clindamycin;   Drug: Ampicillin gentamicin clindamycin
Outcome Measure: To determine the courses of antibiotics needed after vaginal delivery and after cesareans in pregnancies complicated by chorioamnionitis.
6 Recruiting Antibiotic Prophylaxis in Laparoscopic Cholecystectomy
Condition: Cholelithiasis
Interventions: Drug: Ciprofloxacin;   Drug: Ampicillin-sulbactam;   Drug: Placebo
Outcome Measures: Surgical site infection;   Extra-abdominal infections;   Adverse events.;   Quality of life
7 Recruiting Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days With Clinical or Confirmed Late-onset Sepsis
Condition: Sepsis
Interventions: Drug: Meropenem;   Drug: Ampicillin + gentamicin or cefotaxime + gentamicin
Outcome Measures: percentage of patients with a favorable outcome in the two arms;   Nature, frequency and numbers of clinical and biological adverse events
8 Not yet recruiting Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth: a Randomized Controlled Trial
Condition: Endometritis
Interventions: Drug: Antibiotic prophylaxis;   Drug: Ampicillin;   Drug: Gentamycin;   Drug: Clindamycin
Outcome Measures: Endometritis rate;   Puerperal fever
9 Unknown  Operational Research Management for Children With Severe Pneumonia
Condition: Pneumonia
Interventions: Other: Amoxycilline, Cephradine followed by follow up on day 3;   Other: Injectable Ampicillin followed by urgent referral
Outcome Measures: Proportion of Severe Pneumonia cases approapriately treated as per the Modified IMCI guideline;   Proportion of severe pneumonia cases complied appropriately with followup advice given by the health care providers;   Proportion of childhood pneumonia cases treated by trained service provider
10 Not yet recruiting Patients Response to Early Switch To Oral:Osteomyelitis Study
Condition: Osteomyelitis
Interventions: Drug: oral antibiotics;   Procedure: intravenous antibiotics
Outcome Measures: Clinical Failures;   Evaluation of adverse events related to the use of antibiotics;   Cost of care from the hospital perspective
11 Recruiting Preoperative Antibiotics Study
Condition: Cleft Palates
Interventions: Drug: Unasyn;   Other: saline solution
Outcome Measures: The study aims to assess the efficacy of prophylactic antibiotics in cleft surgery.;   Secondary objective of this study is to evaluate the effects of preoperative antibiotics administered on post operative outcome following primary closure of cleft secondary palate.
12 Recruiting Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Conditions: Infection;   Hypertension;   Anesthesia;   Pain;   Reflux;   Nausea;   Edema;   Hyperlipidemia;   Hypotension;   Hypercholesterolemia
Intervention: Drug: Ampicillin
Outcome Measures: Composite of pharmacokinetic outcomes for understudied drugs in children;   Composite pharmacodynamic outcomes of understudied drugs in children;   Biomarkers associated with understudied drugs in children
13 Not yet recruiting Community-Associated Uropathogen Antimicrobial Resistance Among Emergency Department Patients With Acute Pyelonephritis
Condition: Pyelonephritis
Intervention: Other: No intervention
Outcome Measure: Prevalence of antimicrobial resistant E. coli in the U.S.
14 Recruiting Neonatal and Paediatric Pharmacokinetics of Antimicrobials Study
Condition: Paediatric Antimicrobial Pharmacokinetics
Intervention:
Outcome Measure: The pharmacokinetic parameters of drug clearance and volume of distribution for each penicillin.
15 Recruiting Initial Antibiotics and Delayed Appendectomy for Acute Appendicitis
Condition: Acute Appendicitis
Intervention: Drug: Piperacillin + Amoxicillin
Outcome Measures: Number of treatment failures;   Cost-saving of initial nonoperative treatment for early appendicitis
16 Recruiting Study to Demonstrate That Antibiotics Are Not Needed in Moderate Acute Exacerbations of COPD
Condition: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Drug: Sultamicillin;   Drug: Placebo
Outcome Measures: Additional antibiotic therapy to study medication during treatment period or until the test of cure visit (at day 30);   To evaluate long-term consequences of Placebo treatment;   To assess patient's clinical improvement relative to treatment;   To assess additional efficacy endpoints and health outcome evaluations

These studies may lead to new treatments and are adding insight into Ampicillin etiology and treatment.

A major focus of Ampicillin research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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