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Angiogram Medical Research Studies

Up-to-date List of Angiogram Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Angiogram Medical Research Studies

Rank Status Study
1 Recruiting Fluorescence Versus Intraoperative Cholangiography in the Visualization of Biliary Tree Anatomy
Conditions: Cholelithiasis;   Gallbladder Polyps
Interventions: Device: Fluorescence cholangiography (da Vinci surgical system);   Other: Virtual cholangiography;   Procedure: Conventional IOC
Outcome Measures: To evaluate the ability of a ICG-fluorescence guidance in visualizing the biliary anatomy and to compare accuracy to conventional intraoperative cholangiography;   To evaluate the ability of fluorescence-based imaging in visualizing the biliary tree anatomy;   To evaluate the ability of enhanced reality in visualizing the biliary anatomy intra-operatively, especially the cysticocholedochal junction;   To evaluate time required for the visualization of biliary tree anatomy for each modality : fluorescence, enhanced reality, conventional intraoperative cholangiography
2 Recruiting Use of Indocyanine Green Cholangiography and Methylene Blue to Detect Postoperative Biliary Fistula After Hepatectomy
Condition: Liver Disease
Interventions: Procedure: indocyanine green fluorescent cholangiography;   Drug: methylene blue
Outcome Measure: biliary fistula rate
3 Unknown  ERC Via Double-Balloon-Enteroscopy in Patients With Biliodigestive Anastomosis
Condition: Cholangiography
Interventions: Procedure: cholangiography via double-balloon enteroscopy;   Procedure: MR cholangiography
Outcome Measure:
4 Unknown  EUS Prior to ERCP in the Positive Setting of Positive Intraoperative Cholangiogram (IOC) During Cholecystectomy
Conditions: Calculi;   Stenosis of Bile Duct
Outcome Measures: Bile Duct;   Lesions;   Bile duct;   Diverticulum;   ERCP
5 Recruiting Near Infrared Fluorescence Cholangiography (NIRF-C) During Cholecystectomy -- Use in Acute Cholecystitis Sub-Study
Conditions: Acute Cholecystitis;   Acute Cholangitis
Interventions: Drug: Indocyanine Green (ICG);   Device: Near Infrared Fluorescence Cholangiography (NIRF-C)
Outcome Measures: Adverse events related to use of indocyanine green (ICG);   Anatomic identification with NIRF-C and IOC;   Procedure time
6 Recruiting Percutaneous Transhepatic Cholangiography Versus Endoscopic Ultrasound Guided Biliary Drainage
Condition: Malignant Biliary Obstruction
Intervention: Procedure: Percutaneous transhepatic cholangiography vs. endoscopic biliary drainage
Outcome Measures: Pain: Post-procedural pain as measured by visual analogue score (VAS) at 2, 24, and 72 hours following the procedures;   Major complications including bile leak, bleeding, sepsis or death
7 Recruiting The Use of Fluorescent Imaging for Intraoperative Cholangiogram During Laparoscopic Cholecystectomy
Conditions: Cholelithiasis;   Cholecystitis;   Pancreatitis Biliary;   Colic of Gallbladder Without Mention of Cholecystitis
Intervention: Drug: Indocyanine Green (ICG)
Outcome Measures: operative time;   Safety of operative technique
8 Recruiting A Pilot Dosing and Timing Study to Optimize Imaging When Utilizing Endoscopic Fluorescence Imaging System During Laparoscopic Biliary and Hepatic Operations
Condition: Biliary Anatomy
Intervention: Device: PINPOINT System
Outcome Measure: Ease of Identification of Biliary Anatomy as Scored by the Surgeon (1-5 scale)
9 Unknown  Intravenous-Morphine and Glucagon-Usage Enhanced MR Cholangiography
Condition: Liver Disease
Intervention: Drug: morphine and glucagon
Outcome Measure: MRCP visibility
10 Unknown  Endoscopic Ultrasound as an Early Diagnostic Tool for Primary Sclerosing Cholangitis
Condition: Primary Sclerosing Cholangitis
Outcome Measure: Suspicion of PSC in endosonographic ultrasound
11 Recruiting Prospective Randomized Study of PTC and EUS-guided Drainage of the Bile Duct
Condition: Jaundice
Interventions: Device: biliary drainage;   Device: EUS guided biliary drainage
Outcome Measures: Morbidity rate;   efficacy;   feasibility;   biliary drainage duration;   quality of life
12 Recruiting Diagnosis of Bile Duct Strictures
Conditions: Bile Duct Stricture;   Cholangiocarcinoma;   Pancreatic Cancer;   Chronic Pancreatitis
Intervention: Other: brushing of bile duct strictures for cytology
Outcome Measures: • Sensitivity accuracy of cytology, FISH and mutation profiling using histologic diagnosis in conjunction with clinical and/or imaging follow-up as the gold standard.;   • Specimen adequacy;   • Complications (pancreatitis, bleeding, perforation, cholangitis);   • Technical success and ease of procedure
13 Recruiting Prospective Multicenter Evaluation of a New Short-access-cholangioscope for Biliary Duct Strictures and Gall Stones
Conditions: Choledocholithiasis;   Common Bile Duct Neoplasms;   Cholestasis
Intervention: Device: cholangioscopy (Frimberger)
Outcome Measures: Efficacy of cholangioscopy in gallstone therapy and stricture diagnosis;   Complication rate;   Gallstone therapy;   Stricture diagnostic
14 Unknown  Single Port Access (SPA) Cholecystectomy Versus Standard Laparoscopic Cholecystectomy
Conditions: Symptomatic Gallbladder Stones;   Cholecystitis;   Biliary Pancreatitis
Interventions: Procedure: SPA cholecystectomy;   Procedure: Laparoscopic cholecystectomy
Outcome Measures: Cosmesis, body image and quality of life scale;   Post-operative morbidity;   Post-operative pain;   Operative time
15 Recruiting Comparison of Endoscopic Radiofrequency Ablation Versus Photodynamic Therapy for Inoperable Cholangiocarcinoma
Condition: Cholangiocarcinoma
Interventions: Procedure: Self expanding metallic stent (SEMS);   Procedure: Endoscopic radiofrequency ablation (ERFA);   Procedure: Photodynamic therapy (PDT)
Outcome Measures: stent patency;   overall survival rate
16 Recruiting Functional MRC With Eovist for Acute Cholecystitis
Condition: Acute Cholecystitis
Outcome Measure: Number of positive cases of acute cholecystitis
17 Recruiting Mitomycin C Therapy for Patients With Primary Sclerosing Cholangitis
Condition: Primary Sclerosing Cholangitis
Interventions: Drug: Mitomycin C;   Drug: Normal saline
Outcome Measures: Therapeutic Effect on Disease Prognosis as Determined by the Mayo Natural History Model for Primary Sclerosing Cholangitis;   Number of Patients with Adverse Events;   Frequency of Endoscopic Interventions Needed to Manage Disease-related Complications
18 Not yet recruiting Efficacy and Safety Study of PDT Using Photofrin in Unresectable Advanced Perihilar Cholangiocarcinoma
Condition: Hilar Cholangiocarcinoma
Interventions: Drug: Photodynamic therapy-Photofrin;   Procedure: Stenting procedure;   Drug: Chemotherapy regimen Gemcitabine/Cisplatin
Outcome Measures: Overall survival;   Time-to-bilirubin response;   Best overall tumor response;   Time-to-tumor progression;   Change from baseline in performance status on the Karnofsky Performance Scale (KPS);   Change from baseline in health-related quality of life on the 4- and 7-point European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30);   Change from baseline in health-related quality of life on the 4- and 7-point EORTC QLQ-C30
19 Recruiting RCT of the Double Wire Technique With or Without Transpancreatic Sphincterotomy for Difficult Common Bile Duct Cannulation
Conditions: Cholangiopancreatography, Endoscopic Retrograde;   Sphincterotomy, Endoscopic;   VATER'S AMPULLA
Intervention: Procedure: Transpancreatic sphincterotomy
Outcome Measures: Number of attempts needed to achieve deep cannulation with a second wire.;   Time from randomization to deep cannulation.

These studies may lead to new treatments and are adding insight into Angiogram etiology and treatment.

A major focus of Angiogram research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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