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Anxiety Medical Research Studies

Up-to-date List of Anxiety Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Anxiety Medical Research Studies

Rank Status Study
1 Recruiting Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Conditions: Autism Spectrum Disorders;   Autism;   Asperger's Syndrome;   Pervasive Developmental Disability - Not Otherwise Specified;   Obsessive-compulsive Disorder;   Social Phobia;   Generalized Anxiety Disorder;   Specific Phobia;   Separation Anxiety Disorder
Interventions: Behavioral: Personalized Cognitive-behavioral therapy;   Behavioral: Standard Practice Cognitive-behavioral therapy
Outcome Measures: Change from Baseline in Anxiety severity on the Pediatric Anxiety Rating Scale after 16 weeks of treatment.;   Change from Baseline in Anxiety severity on the Clinical Global Impressions Scale after 16 weeks of treatment.;   Change from Baseline in Anxiety severity on the Child and Adolescent Symptom Inventory after 16 weeks of treatment.;   Change from Baseline in Anxiety related impairment as measured by the Childhood Anxiety Impact Scale after 16 weeks of treatment.
2 Recruiting Retraining Attention to Treat Alcohol Dependence and Social Anxiety
Conditions: Alcohol Drinking;   Anxiety Disorders
Interventions: Behavioral: Anxiety Attention Training;   Behavioral: Alcohol Attention Training
Outcome Measures: Liebowitz Social Anxiety Scale;   30-Day Timeline Follow-back for Alcohol and Drugs
3 Recruiting Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders
Conditions: Anxiety Disorders;   Mood Disorders
Interventions: Behavioral: Single Diagnosis Treatment Protocol;   Behavioral: Unified Protocol (UP)
Outcome Measures: Anxiety Disorders Interview Schedule for DSM-IV-Lifetime Version;   Clinical Global Impression Severity (CGI-S) and Improvement Scales (CGI-I);   Structured Interview Guide for the Hamilton Anxiety and Depression Rating Scale (SIGH-A and SIGH-D);   Mini or Superlite-ADIS-IV;   Superlite-ADIS-IV;   Yale-Brown Obsessive Compulsive Scale Interview (Y-BOCS);   Panic Disorder Severity Scale (PDSS);   Liebowitz Social Anxiety Scale (LSAS);   Generalized Anxiety Disorder Severity Scale (GADSS);   Post-Traumatic Stress Disorder (PTSD) Symptom Scale-Interview Version (PSS-I);   Beck Depression Inventory (BDI-II);   Beck Anxiety Inventory (BAI);   Overall Anxiety Sensitivity and Impairment Scale (OASIS);   Work and Social Adjustment Scale (WSAS);   Credibility/Expectancy Questionnaire;   Rand-modified, Medical Outcomes Study 36-item Short-Form Health Survey (Rand-MOS-SF-36);   University of Rhode Island Change Assessment;   Homework Compliance Scale;   Anxiety Sensitivity Index;   Anxiety Control Questionnaire Revised (ACQ-R);   Behavioral Inhibition/Behavioral Activation Scale (BIS/BAS);   Eysenck Personality Questionnaire-Revised-Short Form (EPQR-S);   Emotion Regulation Questionnaire (ERQ);   Eysenck Personality Questionnaire-Revised - Short Form (EPQR-S)
4 Recruiting Integrated CBT for Cannabis Dependence With Co-occurring Anxiety Disorders
Conditions: Cannabis Dependence;   Anxiety Disorders
Interventions: Behavioral: Cognitive-Behavioral Therapy;   Behavioral: Motivation Enhancement Therapy;   Behavioral: Integrated Cannabis and Anxiety Reduction Treatment;   Behavioral: False Safety Behavior Elimination Therapy
Outcome Measures: cannabis use;   cannabis-related problems;   Anxiety
5 Recruiting Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Conditions: Autism Spectrum Disorders;   Autism;   Asperger's Syndrome;   Pervasive Developmental Disability - Not Otherwise Specified;   Obsessive-compulsive Disorder;   Social Phobia;   Generalized Anxiety Disorder;   Specific Phobia;   Separation Anxiety Disorder
Interventions: Behavioral: Personalized Cognitive-behavioral therapy;   Behavioral: Standard Practice Cognitive-behavioral therapy
Outcome Measures: Change from Baseline in Anxiety severity on the Pediatric Anxiety Rating Scale after 16 weeks of treatment;   Change from Baseline in Anxiety severity on the Clinical Global Impressions Scale after 16 weeks of treatment.;   Change from Baseline in Anxiety severity on the Child and Adolescent Symptom Inventory after 16 weeks of treatment.;   Change from Baseline in Anxiety related impairment as measured by the Childhood Anxiety Impact Scale after 16 weeks of treatment.
6 Recruiting Computerized Anxiety Treatment for Suicide
Conditions: Anxiety;   Suicide
Interventions: Other: Cognitive Anxiety Sensitivity Treatment;   Other: Physical Health Education Training
Outcome Measures: Anxiety Sensitivity Index-3 (ASI-3);   Beck Suicide Scale (BSS)
7 Not yet recruiting Patient Anxiety Associated With Lymphedema Surveillance Method
Condition: Anxiety
Interventions: Device: Bio-Impedance Testing;   Other: Anxiety Questionnaire;   Other: Traditional Circumferential Measurements
Outcome Measures: Anxiety;   Upper Extremity Limb Volume
8 Recruiting Cognitive Behavior Therapy for Health Anxiety: A Comparison of Three Forms of Self-help
Conditions: Severe Health Anxiety;   Somatic Symptom Disorder;   Illness Anxiety Disorder
Interventions: Behavioral: Cognitive Behavior Therapy, exposure and response prevention (Internet, guided);   Behavioral: Cognitive Behavior Therapy, exposure and response prevention (Internet, unguided);   Behavioral: Cognitive Behavior Therapy, exposure and response prevention (Book, unguided)
Outcome Measures: Health Anxiety Inventory (HAI);   Illness Attitude Scale (IAS);   Whiteley Index (WI);   Montgomery-Åsberg Depression Rating Scale - Self report (MADRS-S);   Beck Anxiety Inventory (BAI);   Anxiety Sensitivity Index (ASI);   Sheehan Disability Scale (SDS);   Trimbos and institute of medical technology assessment cost questionnaire (TIC-P);   Euroqol-5D (EQ-5D);   Obsessive Compulsive Inventory Revised (OCI-R);   Yale-Brown Obsessive Compulsive Scale (Y-BOCS);   Alcohol Use Disorders Identification Test (AUDIT);   Insomnia Severity Index (ISI);   Self-rated health 5 (SRH-5);   The Swedish Scales of Personalities;   Quality of Life Inventory (QOLI)
9 Recruiting Brief Behavioral Treatment for Anxiety in Young Children
Conditions: Obsessive-compulsive Disorder;   Social Phobia;   Generalized Anxiety Disorder;   Specific Phobia;   Separation Anxiety Disorder;   Selective Mutism;   Anxiety Disorder, Not Otherwise Specified
Interventions: Behavioral: Parent-Led Exposure Therapy;   Other: Treatment As Usual
Outcome Measures: Pediatric Anxiety Rating Scale;   Clinical Global Impression - Severity;   Clinical Global Improvement
10 Recruiting Combination of Active or Placebo Attentional Bias Modification Treatment (ABMT) to Either Cognitive Behavioral Group Therapy (CBGT) or Psychoeducational Control Intervention (PCI) for Anxiety Disorders in Children
Conditions: Generalized Anxiety Disorder;   Separation Anxiety Disorder;   Social Anxiety Disorder
Interventions: Other: Attentional Bias Modification Treatment (ABMT) - Active;   Other: Attentional Bias Modification Treatment - Placebo;   Behavioral: Cognitive Behavioral Group Therapy;   Behavioral: Psychoeducational Control Intervention
Outcome Measures: Pediatric Anxiety Rating Scale (PARS) / continuous;   Clinical Global Impression - Improvement Scale (CGI-I) / dichotomous;   Screen for Children and Anxiety Related Emotional Disorders (SCARED);   Childhood Depression Inventory (CDI);   Swanson, Nolan, and Pelham scale - Version IV (SNAP-IV);   Spence Children's Anxiety Scale (SCAS);   Neuropsychological measures;   Biological measures
11 Recruiting Mindfulness Based Cognitive Therapy for Youth With Anxiety at Risk for Bipolar Disorder
Conditions: Childhood Anxiety;   Parents With Bipolar Disorder;   Children at Risk for Bipolar Disorder
Interventions: Behavioral: Mindfulness Based Cognitive Therapy fpr Anxious Children (MBCT-C);   Behavioral: Waitlist Control
Outcome Measures: The Pediatric Anxiety Rating Scale;   Change in other Anxiety;   Mood;   Behavioral;   Quality of Life
12 Recruiting Outcome of Cognitive Behavioral Therapy for Patients With Severe Health Anxiety Treated in Groups
Conditions: Severe Health Anxiety;   Hypochondriasis;   Illness Anxiety Disorder;   Somatic Symptom Disorder;   Personality Disorders
Interventions: Behavioral: Group-Cognitive Behavioral Therapy;   Other: Wait-List with treatment as usual
Outcome Measures: Change in degree of health Anxiety on the questionnaire Whiteley Index 7 (WI-7) from baseline to 6 month after 12 weeks group-CBT intervention;   Cure from severe health Anxiety;   Change in degree of health Anxiety on the questionnaire Health Anxiety Inventory-14/18 (HAI) from baseline to 6 months after 12 weeks group-CBT intervention;   Personality Inventory for DSM-5 Total Score (PID-5);   Social level of Functioning (SF-36);   Symptome Check List-90-Revised (SCL-90-R) subscales;   WHO-5 Well-being Index;   EQ-5D (EuroQol);   CAGE;   Illness Perception Questionnaire (IPQ);   Client Satisfaction Questionnaire (CSQ);   Global Assessment of Functioning (F-GAF);   Resource Use from Register data for health and social care (cost/effectiveness)
13 Recruiting Smoking Termination / Anxiety Reduction Treatment (ST/ART)
Conditions: Smoking;   Anxiety Disorders
Interventions: Drug: Nicotine Patch;   Behavioral: Smoking Termination and Anxiety Reduction Treatment;   Behavioral: Education-Supportive Psychotherapy
Outcome Measure: Smoking status
14 Recruiting HIV Prevention for HIV-Negative Men Via Reduction of Social Anxiety
Conditions: Social Anxiety;   Substance Use
Intervention: Behavioral: Reduction of social Anxiety & substance use in gay/bi men
Outcome Measures: Instances of unprotected anal intercourse with sexual partners who are HIV-positive or of unknown HIV status;   Severity of social Anxiety and instances substance use in sexual situations
15 Unknown  Anxiety Sensitivity Treatment for Heroin Users
Condition: Anxiety
Intervention: Behavioral: Anxiety sensitivity therapy
Outcome Measures: Anxiety Sensitivity Index-3;   Timeline Follow Back 90 days
16 Recruiting A Study Comparing Two Treatments for Child With Anxiety
Condition: Anxiety
Interventions: Behavioral: Experimental treatment;   Behavioral: Traditional Treatment
Outcome Measures: Pediatric Anxiety Rating Scale;   Pediatric Anxiety Rating Scales
17 Recruiting Clinical Management of Anxiety and Access to Health Care
Condition: Dental Anxiety
Intervention: Behavioral: Computerized Dental Anxiety Treatment
Outcome Measures: Change in Modified Dental Anxiety Scale;   Change in Anxiety Disorders Interview Schedule for DSM-IV
18 Unknown  Anxiety Treatment Inspired by Dialectical Behavior Therapy (DBT)
Condition: Treatment Resistant Anxiety Disorders
Intervention: Behavioral: DBT-inspired Anxiety treatment
Outcome Measures: Change in Anxiety (Clark, D. M., Ehlers, A., McManus, F., Hackmann, A., Fennell, M., Campbell, H., Flower, T., Davenport, C., Louis, B., 2003).;   Positive Negative Affect Scale (PANAS), (Watson, Clark & Tellegan, 1988).;   Overall Anxiety Severity and Impairment Scale (OASIS), (Barlow, 2011).;   Overall Depression Severity and Impairment Scale (ODSIS), (Barlow, 2011).;   Difficulties in Emotion Regulation Scale (DERS), (Gratz & Roemer, 2004).;   Five Fazet Mindfulness Questionnaire (Baer, Smith, Hopkins, Krietemeyer, & Toney, 2006).;   WHOQOL-BREF (Skevington, Lofty, O´Connel & WHOQOL Group, 2004).;   Structured Clinical Interview for DSM-IV-I (SCID-I), (First, Spitzer, Gibbon, & Williams, 2001).
19 Not yet recruiting Delivery of Anxiety Disorder Treatment in Addictions Centers
Conditions: Anxiety Disorders;   Substance Use Disorders
Interventions: Behavioral: CALM-SUD;   Behavioral: Treatment as usual
Outcome Measures: Brief Symptom Inventory;   Timeline Follow Back;   Overall Anxiety Severity and Impairment Scale;   urine toxicology screen;   Patient Health Questionnaire-8;   Anxiety Sensitivity Index;   Panic Disorder Severity Scale;   Social Phobia Inventory;   Penn State Worry Questionnaire;   Posttraumatic Stress Disorder Checklist
20 Recruiting Effects of Tai Chi Chuan on Psychobiological Indicators of Anxiety and Sleep Quality in Young Adults
Condition: Anxiety
Interventions: Behavioral: Anxiety Management Education;   Behavioral: 10 week tai chi intervention;   Behavioral: Enhanced tai chi instruction
Outcome Measures: Retention of randomized subjects during intervention;   Retention of randomized subjects for follow-up;   Adherence to out-of-class practice;   Adherence to practice after the intervention;   Collect preliminary data on the relationship between tai chi chuan practice and changes in symptoms of Anxiety to aid in future study planning.;   Collect preliminary data on the relationship between tai chi chuan practice and changes in symptoms of sleep quality to aid in future study planning.;   Collect preliminary data on the relationship between tai chi chuan practice and changes in psychological functioning to aid in future study planning.;   Collect preliminary data on the relationship between tai chi chuan practice and changes in physiological arousal to aid in future study planning.

These studies may lead to new treatments and are adding insight into Anxiety etiology and treatment.

A major focus of Anxiety research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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