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Aristospan Medical Research Studies

Up-to-date List of Aristospan Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Aristospan Medical Research Studies

Rank Status Study
1 Recruiting Intralesional Steroids in the Treatment of Alopecia Areata
Condition: Alopecia Areata
Interventions: Drug: Triamcinolone 2.5 mg/ml;   Drug: Triamcinolone 5 mg/ml;   Drug: Triamcinolone 10 mg/ml;   Drug: Intralesional Saline
Outcome Measures: SALT Score;   Number of adverse events
2 Recruiting Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis
Conditions: Uveitis;   Intermediate Uveitis;   Posterior Uveitis;   Panuveitis;   Noninfectious Uveitis
Intervention: Drug: triamcinolone acetonide (Triesence®)
Outcome Measures: Incidence of adverse events;   Central subfield thickness using optical coherence tomography (OCT);   Vitreous haze grade;   Change in intraocular pressure (IOP)
3 Recruiting Intraocular Bevacizumab Compared With Intraocular Triamcinolone in Patients With Diabetic Macular Edema
Condition: Diabetic Macular Edema
Interventions: Drug: Bevacizumab (Avastin);   Drug: Triamcinolone;   Drug: Sham;   Procedure: Lucentis
Outcome Measures: Efficacy of the treatment assessed with visual acuity measured by ETDRS charts and central retinal thickness as measured by standard Optical Coherence Tomography (OCT);   To explore the structural mechanisms of the effect on diabetic macular edema as assessed by fluorescein angiography and ultra high-resolution optical coherence tomography. To observe the changes in retinal function a microperimetry is assessed.
4 Unknown  Efficacy Study of Triamcinolone and Bevacizumab Intravitreal for Treatment of Diabetic Macular Edema
Condition: Diabetic Macular Edema
Interventions: Drug: Bevacizumab intravitreal;   Drug: Triamcinolone;   Drug: Triamcinolone + Bevacizumab
Outcome Measures: Measurement of visual acuity (E Snellen);   Tonometry;   Measurement of retinal thickness by OCT
5 Recruiting Early Treatment for Acute ACL Tear
Condition: Anterior Cruciate Ligament (ACL) Tears
Interventions: Drug: Kenalog or placebo;   Drug: Kenalog then Placebo;   Drug: Kenalog;   Drug: Placebo
Outcome Measures: Efficacy of Kenalog to alleviate knee pain;   Kenalog therapy improves levels of a panel of inflammatory (cytokine), meniscus and cartilage metabolism and oxidative stress biomarkers
6 Recruiting Combined Restylane and Triamcinolone Acetonide Injections for the Treatment of Alopecia Areata
Condition: Alopecia Areata
Interventions: Drug: Intralesional Triamcinolone Acetonide 10 mg/mL (Kenalog-10);   Device: Restylane
Outcome Measures: Change in alopecia areata half head severity score (AAHHSS) at 12 weeks compared to baseline;   Number of adverse events reported by subjects
7 Unknown  Sub-tenon Triamcinolone Acetonide in Age-Related Macular Degeneration as Adjunct to Ranibizumab
Condition: Wet Macular Degeneration
Interventions: Drug: Ranibizumab;   Drug: Triamcinolone Acetonide
Outcome Measures: Gains in visual acuity;   Changes in intra-ocular pressure;   Rates of re-treatment;   Rate of vision loss;   Rate of cataract progression;   • Changes in choroid vessel activity in lesion growth and activity at choroid
8 Recruiting Randomized Controlled Trial of Endoscopic Dilation: Triamcinolone Injection
Condition: Dysphagia
Interventions: Device: Dilation;   Drug: Triamcinolone Injection;   Device: Esophagogastroduodenoscopy (EGD)
Outcome Measures: Number of Visits to Receive Esophageal Dilation During the 12 Month Follow-up Period;   Final Dysphagia Score
9 Unknown  Treatment Of Radiation Retinopathy Trial
Condition: Uveal Melanoma
Interventions: Drug: ranibizumab;   Drug: triamcinolone acetonide;   Other: sham
Outcome Measures: To demonstrate a statistically significant superiority of intravitreal ranibizumab (0.5mg) or triamcinolone acetonide (4.0mg) to no treatment, in the mean change from baseline in best corrected visual acuity (BCVA);   To evaluate the time course of BCVA changes on ranibizumab (0.5 mg) and triamcinolone acetonide (4.0mg) relative to no treatment.;   To evaluate the effects of ranibizumab (0.5 mg) and triamcinolone acetonide (4.0mg) on central retinal thickness, severity of retinopathy and other anatomical changes relative to no treatment;   To demonstrate a possible relation between decreasing levels of angiogenic factors (such as VEGF) in the anterior chamber fluid and a good response to treatment with ranibizumab or triamcinolone acetonide, and radiation retinopathy
10 Unknown  Subacromial Corticosteroid Injection for Hemiplegic Shoulder Pain
Condition: Shoulder Pain
Interventions: Drug: Lidocaine;   Drug: Triamcinolone + Lidocaine
Outcome Measures: BPI 12 (Brief Pain Inventory, Question 12) pain questionnaire;   BPI 13-15 (Brief Pain Inventory, Questions 13-15) pain questionnaire;   BPI 23 (Brief Pain Inventory, Question 23) pain questionnaire;   Fugl-Meyer Motor Assessment;   Pain free external rotation range of motion (ROM);   Pain free abduction range of motion (ROM)
11 Unknown  Local Triamcinolone Injection in Active Thyroid Orbitopathy
Condition: Thyroid Disease
Intervention: Drug: Triamcinolone
Outcome Measures: Comparing the effectiveness of subconjunctival and peribulbar Triamcinolone injection to systemic Steroid therapy for patients with active thyroid orbitopathy .;   To check if the level of TSH Receptor antibodies are affected by the local injection.
12 Recruiting Chalazia Treatment Study
Condition: Chalazion
Interventions: Drug: 5-fluorouracil Injection;   Drug: Triamcinolone Acetonide;   Procedure: Incision and Curettage;   Drug: Triamcinolone Acetonide/5-fluorouracil mixture
Outcome Measure: Size of chalazion
13 Unknown  Safety and Efficacy of Triamcinolone Acetonide Combined With Laser, Bevacizumab Combined With Laser Versus Laser Alone for the Treatment of Diffuse Non-tractional Diabetic Macular Edema
Condition: Diabetic Macular Edema
Interventions: Other: Grid laser;   Drug: Triamcinolone Acetonide;   Drug: Bevacizumab
Outcome Measures: Best-Corrected Visual Acuity (BCVA);   To assess the safety of intravitreal Triesence (r);   To measure average change in mean central macular thickness in each group.;   To assess the safety of intravitreal Avastin (r);   To assess the safety of intravitreal grid photocoagulation
14 Unknown  Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel
Conditions: Dental Pain;   Postoperative Pain
Interventions: Drug: benzocaine;   Drug: TAC alternate gel
Outcome Measures: visual analogue scale score;   blood pressure;   oxygen saturation;   heart rate
15 Recruiting Postoperative Pain Control Following Vitreoretinal Surgery
Conditions: Retinal Detachment;   Proliferative Vitreoretinopathy;   Retinoschisis
Interventions: Drug: Triamcinolone;   Drug: Bupivicaine Hydrochloride
Outcome Measures: Subjective pain levels on a 10. scale questionnaire;   Dosage of pain medication;   Measurements of ocular motility
16 Unknown  Treatment of Upper Eyelid Retraction Related to Thyroid-associated Ophthalmopathy Using Subconjunctival Triamcinolone Injections
Condition: Thyroid-associated Ophthalmopathy
Intervention: Drug: subconjunctival triamcinolone injection
Outcome Measures: change of Eyelid retraction grade;   change of Eyelid swelling
17 Unknown  Treatment of Bevacizumab and Triamcinolone in Treatment or Macular Edema Secondary to CRVO
Conditions: Macular Edema;   Central Retinal Vein Occlusion
Intervention: Drug: bevacizumab and triamcinolone
Outcome Measures: Changes in Best corrected visual acuity and macular edema measured with OCT;   Report treatment complications
18 Unknown  The Comparison Between the Therapeutic Affect of Intravitreal Diclophenac and Triamcinolone in Persistent Uveitic Cystoids Macular Edema
Conditions: Uveitis;   Cystoid Macular Edema
Interventions: Drug: Diclophenac;   Drug: Triamcinolone
Outcome Measure:
19 Recruiting Efficacy Comparison Study of Steroids to Control Post-operative Inflammation
Conditions: Inflammation;   Intraocular Pressure
Interventions: Drug: Subtenon 20-mg triamcinolone injection;   Drug: Placebo
Outcome Measures: Anterior chamber reaction;   rate of increased intraocular pressure over 21 mmHg;   Changes of anterior chamber reaction over time
20 Recruiting Study to Evaluate Fractional Collagen Synthesis Within Keloid Scars and Identify Biomarkers of Keloid Scars
Condition: Fibrosis
Interventions: Drug: Triamcinolone acetonide;   Drug: Placebo
Outcome Measures: Fractional synthesis of collagen in keloid scars;   Keloid scar volume before first dose and immediately prior to surgery;   Keloid scar surface area before first dose and immediately prior to surgery;   Keloid scar length and height before first dose and immediately prior to surgery;   Keloid scar vascularity before first dose and immediately prior to surgery

These studies may lead to new treatments and are adding insight into Aristospan etiology and treatment.

A major focus of Aristospan research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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