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Arthritis Medical Research Studies

Up-to-date List of Arthritis Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Arthritis Medical Research Studies

Rank Status Study
1 Recruiting Arthritis Health Journal Proof of Concept Study
Condition: Rheumatoid Arthritis
Intervention: Behavioral: Arthritis Health Journal
Outcome Measures: Self-Management Behaviours;   Self-Efficacy;   Consumer Effectiveness;   Patient Satisfaction with Care
2 Recruiting Employment and Arthritis: Making it Work
Conditions: Rheumatoid Arthritis;   Ankylosing Spondylitis;   Lupus Erythematosus, Systemic;   Psoriatic Arthritis;   Other Connective Tissue Diseases;   Spondylarthropathy
Intervention: Behavioral: Employment and Arthritis: Making it Work
Outcome Measures: Efficacy analysis of at work productivity;   Efficacy analysis of work cessation;   Cost effectiveness analysis of at work productivity;   Temporary work cessation;   Occasional work absence;   Reduction in usual amount of time worked;   Changes in employment risk factors;   At-work productivity;   At work productivity;   Cost utility analysis of at work productivity
3 Recruiting Safety and Efficacy of Gardasil in Females With Juvenile Idiopathic Arthritis (JIA)/Seronegative Arthritis
Condition: Arthritis
Intervention: Other: Blood Draws for Serum Titers
Outcome Measures: Serum GMTs at 7 months;   Disease flare;   Peds QL;   Measure serum GMT
4 Unknown  Magnetic Resonance Imaging Follow-up on Temporomandibular Arthritis in Children With Juvenile Idiopathic Arthritis
Condition: Juvenile Idiopathic Arthritis
Intervention: Procedure: Steroid injection into the TMJs.
Outcome Measures: TMJ Arthritis on MRI;   TMJ Arthritis on ultrasound;   Action of current medication on TMJ Arthritis.
5 Recruiting Arthritis Foundation Exercise Program & "10 Keys" to Healthy Aging--Prevention Research Center
Conditions: Arthritis;   Diabetes;   Hypertension;   Preventive Behaviors
Interventions: Behavioral: AFEP;   Behavioral: "10 Keys" to Healthy Aging
Outcome Measures: Preventive Behaviors;   Joint Pain & Stiffness;   Cholesterol (LDL);   Glucose
6 Recruiting The CCP Study: Coordinated Programme to Prevent Arthritis - Can We Identify Arthritis at a Pre-clinical Stage ?
Conditions: Inflammatory Arthritis;   Rheumatoid Arthritis
Intervention:
Outcome Measures: Anti-CCP Ab (+).;   Anti-CCP positive developing I.A;   Anti-CCP positive developing RA;   Presenting complaints;   Predictors for the development of an IA.;   First degree familymembers who are anti-CCP Ab (+)
7 Recruiting Personalized Risk Estimator for Rheumatoid Arthritis Family Study
Condition: First Degree Relatives of Rheumatoid Arthritis Patients
Interventions: Behavioral: PRE-RA;   Behavioral: PRE-RA Plus;   Behavioral: General Rheumatoid Arthritis Education
Outcome Measure: Contemplation Ladder
8 Recruiting To Observe the Impacts of Anti-Tumor Necrosis Factor (TNF) Effectiveness on Improvement in Work Place and Household Productivity for Patients With Psoriatic Arthritis
Conditions: Psoriatic Arthritis;   Work Productivity
Intervention:
Outcome Measures: Evaluation of the impact of long term treatment of psoriatic Arthritis with anti-TNFs on Absenteeism;   Evaluation of the impact of long term treatment of psoriatic Arthritis with anti-TNFs on Presenteeism;   Evaluation of the impact of long term treatment of psoriatic Arthritis with anti-TNFs on work productivity;   Evaluation of the impact of long term treatment of psoriatic Arthritis with anti-TNFs on total daily activity impairment;   To collect Self-reported functional status using Health Assessed Questionnaire (HAQ) questionnaire;   Evaluation of the Anti-TNF treatment effectiveness based percentage of patients achieving American College Rheumatology (ACR) 20/ACR50;   Evaluation of the Anti-TNF treatment effectiveness based percentage of patients achieving ACR 70;   Change in Disease Activity Score (DAS 28);   Change in Maastricht Ankylosing Spondylitis Enthesitis Score;   Change in dactylytis;   Number of swollen and/or tender joints;   Change in levels of rheumatoid factor;   Change in Erythrocyte Sedimentation Rate (ESR);   Change in C-reactive protein (CRP);   Change in Visual Analog Scale (VAS);   Number of patients with serious adverse events
9 Recruiting Yoga as Self-Care for Arthritis in Minority Communities
Conditions: Rheumatoid Arthritis;   Arthritis
Intervention: Behavioral: Yoga
Outcome Measures: To determine the feasibility and acceptability of providing yoga to an urban, minority population with Arthritis;   To determine the appropriateness of specific physical and psychosocial measures for this population and intervention
10 Recruiting The Predictive Value of Ultrasound in Early Rheumatoid Arthritis
Conditions: Rheumatoid Arthritis;   Predictive Value of Ultrasound in Early Rheumatoid Arthritis
Intervention:
Outcome Measures: Persistence of active disease after one year, defined as a Disease Activity Score of 44 joints (DAS44) > 3.4;   Change in Sharp vd Heijde score during the year of inclusion
11 Recruiting Safety and Efficacy Study of Umbilical Cord-Derived Mesenchymal Stem Cells for Rheumatoid Arthritis
Condition: Rheumatoid Arthritis
Interventions: Biological: Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs);   Drug: Rheumatoid Arthritis With Disease-Modifying Drugs (DMARDs);   Biological: UC-MSC+DMARDS
Outcome Measures: Safety of MSC treatment.;   RA Serology;   Disease Activity Score (DAS 28) Index Mean Change From Baseline;   Patient's assessment of pain.
12 Recruiting Evaluation of the Condition of Rheumatoid Arthritis After Treatment
Condition: Rheumatoid Arthritis
Intervention: Drug: The effectiveness of Xeljanz in rheumatoid Arthritis patients
Outcome Measures: Change from baseline of clinical evaluation in rheumatoid Arthritis;   Number of participants with adverse events
13 Unknown  Zostavax in Rheumatoid Arthritis
Conditions: Rheumatoid Arthritis;   Varicella Zoster
Intervention: Drug: Zostavax (varicella zoster virus) vaccine
Outcome Measures: safety;   Immunogenicity
14 Recruiting Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
Conditions: Rheumatoid Arthritis;   Psoriatic Arthritis;   Ankylosing Spondylitis;   Hypertension
Interventions: Drug: Etanercept;   Drug: Adalimumab;   Drug: Certolizumab;   Drug: Infliximab
Outcome Measures: Change from baseline in blood pressure;   Change from baseline in endothelial function
15 Recruiting Full Mouth Disinfection and Antibiotics for Periodontitis in High Activity Rheumatoid Arthritis
Condition: Rheumatoid Arthritis
Intervention:
Outcome Measures: Improvement in the rheumatoid Arthritis disease activity index (DAS28ESR-3v) by >=1.2 points;   Improvement in the rheumatoid Arthritis disease activity score (DAS28ESR-3v) by >=1.2 points;   Improvement in the rheumatoid Arthritis disease activity score when with 3rd variable C reactive protein serum concentration (DAS28CRP-3v) by >=1.2 points;   Improvement in the clinical disease activity index cDAI;   Improvement in the simplified disease activity index cDAI;   Number of patients with 20%, 50% or 70% improvement in the American College of Rheumatology (ACR) response criteria;   Number of patients in ACR/EULAR remission;   % change of B-mode (= gray-scale) and Power-Doppler signals to baseline;   Reduction in the probing pocket depth (PPD) in moderately deep (PPD >/= 4mm) und deep periodontal pockets (PPD > 6mm);   Improvement in clinical attachment level (CAL), as the sum of PPD plus gingival recession (GR);   Reduction in the number of sites with bleeding on probing (BoP)
16 Recruiting Study of Arthritis and Related Conditions
Conditions: Arthritis;   Synovitis
Intervention:
Outcome Measure:
17 Recruiting Pro-calcitonin for Early Detection of Septic Arthritis
Condition: Arthritis, Infectious
Intervention:
Outcome Measure: Septic Arthritis
18 Recruiting Repository Corticotropin Injection To Treat Rheumatoid Arthritis Patients Who Have Failed Three Biologic Therapies.
Condition: Rheumatoid Arthritis
Intervention: Drug: Repository corticotropin injection
Outcome Measures: Change from baseline in the Ritchey-Camp Articular Index;   Change from baseline in the 20-item Health Assessment Questionnaire score;   Change from baseline in the erythrocyte sedimentation rate (ESR);   Change from baseline in the C-Reactive protein (CRP) level
19 Recruiting Abatacept for Patients With Inflammatory Arthritis Associated With Sjögren's Syndrome: an Open-Label Phase II Study
Conditions: Primary Sjogren's Syndrome;   Secondary Sjogren's Syndrome;   Inflammatory Arthritis;   Rheumatoid Arthritis
Intervention: Drug: Abatacept
Outcome Measures: Efficacy of Abatacept in patients with inflammatory Arthritis and Sjogren's Syndrome;   Increase or change in autoantibody profile;   Explore the potential efficacy of Abatacept in the exocrine glandular function
20 Recruiting Sleep Patterns in Children With and Without Juvenile Idiopathic Arthritis
Condition: Juvenile Idiopathic Arthritis
Intervention: Behavioral: comparison of types of sleep disordered breathing
Outcome Measures: Prevalence of Sleep Disordered Breathing;   Measures of Daytime Sleepiness

These studies may lead to new treatments and are adding insight into Arthritis etiology and treatment.

A major focus of Arthritis research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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