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Asprin Medical Research Studies

Up-to-date List of Asprin Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Asprin Medical Research Studies

Rank Status Study
1 Recruiting N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder
Condition: Bipolar Disorder
Interventions: Drug: Asprin;   Dietary Supplement: N-acetyl-cysteine (NAC);   Drug: Asprin and NAC;   Drug: Sugar Pill
Outcome Measures: Proportion of patients demonstrating > 50% decrease in depression scores on the MADRS, as a function of treatment (on aspirin treatment only).;   Modulators of therapeutic response;   Proportion of patients demonstrating > 50% decrease in depression scores on the;   Proportion of patients demonstrating > 50% decrease in depression scores on the MADRS, as a function of treatment (on NAC/Aspirin combination treatment).
2 Recruiting Preconceptional Thromboprophylaxis in Recurrent PREGNANCY LOSSES Caused by Antiphospholipid Syndrome
Conditions: Recurrent Pregnancy Losses;   Positive Anti Phospholipid Syndrome
Intervention: Drug: low molecular weight heparin (enoxeparine)
Outcome Measure: Pregnancy continuation beyond twelve weeks gestation
3 Recruiting Impact of COX2 on Sera Biomarkers From Obese Subjects
Condition: Breast Cancer Survivors
Interventions: Drug: Aspirin;   Dietary Supplement: Omega 3 FFA
Outcome Measures: Biomarker levels;   BMI
4 Recruiting The Princess Alexandra Hospital and the QIMR Berghofer Medical Research Institute Head and Neck Cancer Study
Conditions: Head and Neck Squamous Cell Carcinoma;   Human Papillomavirus
Intervention:
Outcome Measure: To identify exposures associated with an increased risk of head and neck squamous cell carcinoma
5 Unknown  Antiplatelet Effect of Low Doses of Aspirin Taken Every 12 Hours in Patients Undergoing Coronary Artery Bypass Graft and/or Aortic Valve Surgery
Condition: Coronary Arteriosclerosis
Intervention: Drug: Aspirin
Outcome Measures: change in the levels of TXB2 in serum at 12 and 24 hours after administration of aspirin;   change in the levels of 12-HETE in serum at 12 and 24 hours after administration of aspirin;   change in the levels of 11-dehydro TXB2 urinary at 12 and 24 hours after administration of aspirin;   change in the levels of 8-iso-PGF2 alpha urinary at 12 and 24 hours after administration of aspirin;   change in the levels of 2-3 dinor-6-chetoPGF1 alpha at 12 and 24 hours after administration of aspirin;   change in the levels of Verify-NOW Aspirin, platelets crosslinked at 12 and 24 hours after administration of aspirin
6 Unknown  Study of Policosanol to Improve Platelet Reactivity After Percutaneous Coronary Stent Implantation (PCI)
Condition: Coronary Artery Disease
Interventions: Drug: high maintenance clopidogrel;   Drug: routine dual antiplatelet;   Drug: policosanol on the top of dual antiplatelet treatment
Outcome Measures: Platelet aggregation induced by 20μmol/L ADP;   major adverse cardiac events;   Stent thrombosis and TIMI bleeding events
7 Recruiting The Effect of Aspirin on REducing iNflammation in Human in Vivo Model of Acute Lung Injury
Condition: Acute Lung Injury
Interventions: Drug: Aspirin 75mg;   Drug: Lactose powder;   Drug: Aspirin 1200mg
Outcome Measures: Bronchoalveolar lavage IL-8 concentration;   Alveolar inflammatory response biomarkers;   Plasma inflammatory response biomarkers;   Alveolar epithelial and endothelial function and injury biomarkers;   Lipid inflammatory mediators
8 Recruiting First Autologous Transplant on Minimal Residual Disease Markers in Previously Untreated Myeloma Undergoing Initial Treatment With Velcade
Condition: Multiple Myeloma
Interventions: Drug: VELCADE;   Drug: Lenalidomide;   Drug: Dexamethasone;   Drug: DVT prophylaxis;   Drug: Bisphosphonates;   Drug: Liposomal doxorubicin
Outcome Measures: Number of patients with Minimal Residue Disease (MRD) negativity increase by twenty percent or greater;   Correlate MRD status;   Correlate MRD status between induction regimens

These studies may lead to new treatments and are adding insight into Asprin etiology and treatment.

A major focus of Asprin research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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