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Augmentin Medical Research Studies

Up-to-date List of Augmentin Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Augmentin Medical Research Studies

Rank Status Study
1 Recruiting Assessing the Necessity of Prescribing Antibiotics (Clavulin or Clindamycin Versus Placebo) Post-peritonsillar Abscess Drainage
Condition: Peritonsillar Abscess
Interventions: Drug: Clavulin;   Drug: Randomization to Placebo;   Drug: Clindamycin
Outcome Measure: Re-accumulation of the patient's peri-tonsillar abscess
2 Recruiting The SCOUT Study: Short Course Therapy for Urinary Tract Infections in Children
Condition: Urinary Tract Infections
Interventions: Drug: Trimethoprim sulfamethoxazole, amoxicillin-clavulanate, cefixime, or cephalexin;   Drug: Placebo
Outcome Measures: Occurrence of treatment failures between short-course and standard-course therapies;   Occurrence of recurrent infections;   Occurrence of colonization with antimicrobial resistant bacteria;   Occurrence of asymptomatic bacteriuria;   Occurrence of clinical symptoms;   Occurrence of positive urine cultures
3 Recruiting A Clinical Study to Explore Biomarkers for Drug-induced Liver Injury (DILI)
Condition: Healthy
Intervention: Drug: Augmentin tablet
Outcome Measures: Aspartate Aminotransferase (AST);   Alanine Aminotransferase (ALT);   Alkaline phosphatase (ALP)
4 Recruiting The Amputation Surgical Site Infection Trial (ASSIT)
Conditions: Wound Infection;   Amputation Wound
Interventions: Drug: Co-amoxiclav;   Drug: Iodine;   Drug: Metronidazole;   Drug: Chlorhexidine;   Drug: Teicoplanin;   Drug: Clindamycin
Outcome Measures: Surgical Site Infection;   Impact of different skin preparations on infection rates;   Rate of re-intervention;   Mortality;   Satisfactory healing rates;   Quality of life;   Resource use;   • Rate of C. Diff., MSSA (Methicillin Sensitive Staphylococcus Aureus), MRSA (Methicillin Resistant Staphylococcus Aureus) infection;   Mobility;   Pain Control
5 Recruiting Prophylaxis Of Wound Infections- Antibiotics in Renal Donation
Condition: Infection
Interventions: Drug: Co-Amoxiclav;   Drug: Control
Outcome Measures: Rate of infection after surgery;   Ultrasonic evidence of wound healing;   Length of hospital stay;   Readmission rates;   Antibiotic associated side effects;   Return to work and normal activities;   Quality of life;   Relative costs
6 Recruiting Efficacy of Amoxicilline/Clavulanic Acid in Patients Affected by Tic Disorder Colonized by Group A Streptococcus
Condition: Tic Disorders
Interventions: Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: placebo
Outcome Measure: Severity of tic disorder
7 Recruiting Antibiotic Prophylaxis for PEG in Children
Condition: Infection
Interventions: Drug: co-amoxiclav;   Dietary Supplement: Placebo
Outcome Measure: Efficacy
8 Recruiting Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract
Conditions: Vesicoureteral Reflux;   Renal Hypodysplasia, Nonsyndromic, 1;   Chronic Kidney Disease
Interventions: Drug: nitrofurantoin;   Other: No prophylaxis;   Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: Trimethoprim/sulfamethoxazole;   Drug: Cefixime
Outcome Measures: urinary tract infections rate;   febrile urinary tract infections;   renal scars;   serum creatinine (renal function);   hypertension;   proteinuria;   body mass index;   serum cystatin C (renal function)
9 Recruiting Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis
Condition: Sinusitis
Interventions: Drug: Doxycycline;   Drug: Azithromycin;   Drug: Augmentin
Outcome Measures: Number of patients recommended for sinus surgery after 3 weeks of antibiotic therapy;   Number of patients recommended for sinus surgery after 6 weeks of antibiotic therapy;   Change in Quality of Life after 3 weeks of antibiotics;   Change in Quality of Life after 6 weeks of antibiotics;   Change in Nasal endoscopy scores after 3 weeks of antibiotics;   Change in Nasal Endoscopy Score following 6 weeks of antibiotics;   Change in CT Score after 3 weeks of antibiotics;   Change in CT Score after 6 weeks of antibiotics;   Number of patients with antibiotic side effects after a 3 week course of antibiotics;   Number of subjects with antibiotic side effects after a 6 week course of antibiotics
10 Recruiting Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial
Condition: Sinusitis
Interventions: Drug: Amoxicillin-Potassium Clavulanate;   Drug: Placebo
Outcome Measures: Sinonasal outcome test - 22;   Lund Kennedy Endoscopic Score
11 Recruiting Efficacy of Short-Course Antimicrobial Treatment for Young Children With Acute Otitis Media (AOM) and Impact on Antimicrobial Resistance
Condition: Acute Otitis Media
Intervention: Drug: Amoxicillin-Potassium Clavulanate Combination
Outcome Measures: Treatment Failure (Index Episode of AOM);   Nasopharyngeal Colonization with Resistant Pathogens;   AOM Recurrence;   Antibiotic Use;   Symptom Burden;   Treatment Failure (AOM Recurrences);   Protocol-Defined Diarrhea and Diaper Dermatitis
12 Unknown  Middle Meatal Bacteriology During Acute Respiratory Infection in Children
Conditions: Acute Respiratory Infection;   Sinusitis
Interventions: Drug: placebo;   Drug: amoxicillin clavulanate acid
Outcome Measures: Duration of continuous daily symptoms of the acute respiratory infection diagnosed at the study entry.;   duration (days)and severity (grade mild, severe) of different symptoms (clear nasal discharge, coloured nasal discharge, nasal obstruction, cough, throat pain, ear ache, fever, headache, diarrhea);   number of days the child is using the following symptomatic drugs (pain killers, nasal vasoconstrictors, nasal corticosteroids, asthma drugs, antihistamines);   number of days the child is not at school and that the parents are not at work
13 Not yet recruiting Short Duration Treatment of Non-severe Community Acquired Pneumonia
Condition: Community Acquired Pneumonia
Interventions: Radiation: Chest X-ray;   Biological: blood sampling /Cell Counts/ C reactive protein (CRP)/Biochemistry;   Drug: Augmentin;   Drug: Placebo (for Augmentin);   Drug: Beta-Lactams
Outcome Measures: clinical evaluation at Day 15;   clinical evaluation at Day 30
14 Not yet recruiting Patients Response to Early Switch To Oral:Osteomyelitis Study
Condition: Osteomyelitis
Interventions: Drug: oral antibiotics;   Procedure: intravenous antibiotics
Outcome Measures: Clinical Failures;   Evaluation of adverse events related to the use of antibiotics;   Cost of care from the hospital perspective
15 Recruiting Initial Antibiotics and Delayed Appendectomy for Acute Appendicitis
Condition: Acute Appendicitis
Intervention: Drug: Piperacillin + Amoxicillin
Outcome Measures: Number of treatment failures;   Cost-saving of initial nonoperative treatment for early appendicitis
16 Recruiting Short (5 Days) Versus Long (14 Days) Duration of Antimicrobial Therapy for Acute Bacterial Sinusitis in Children
Condition: Sinusitis
Interventions: Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: Placebo
Outcome Measure: Comparison of short course to long course antimicrobials.
17 Recruiting A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures
Condition: Bacteremia
Interventions: Drug: Amoxicillin-Potassium Clavulanate;   Drug: Amoxicillin;   Drug: Chlorhexidine
Outcome Measures: Number of participants receiving a prophylactic dosage with amoxicillin-clavulanate i.v. with bacteremia following dental extractions;   Number of participants receiving a prophylactic dosage with amoxicillin i.v. (following the American Heart Association´s guidelines) with bacteremia after dental extractions
18 Unknown  Examination of the Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections
Condition: Pregnancy Complications
Interventions: Drug: Preventive antibiotic treatment- NITROFURANTOIN;   Drug: Preventive antibiotic treatment- CEPHALEXIN;   Drug: PREVENTIVE TREATMENT- AMOXICILLIN;   Drug: PREVENTIVE TREATMENT- AMOXICILLIN AND CLAVULANATE POTASSIUM;   Drug: PREVENTIVE TREATMENT- CEFUROXIME;   Drug: PREVENTIVE TREATMENT SULFAMETHOXAZOLE AND TRIMETHOPRIM
Outcome Measure: Urinary tract complications
19 Recruiting Clinical Trial Corticoids For Empyema And Pleural Effusion In Children
Conditions: Parapneumonic Pleural Effusion;   Empyema
Interventions: Drug: Dexamethasone;   Drug: Placebo
Outcome Measures: time to resolution;   number of children with complications.;   Number of children with complications attributable to corticoids
20 Unknown  Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use
Conditions: Snoring;   Strep Throat
Interventions: Other: No postoperative antibiotic;   Drug: Amoxicillin;   Drug: Amoxicillin/clavulanate potassium;   Drug: Azithromycin;   Drug: Cefaclor;   Drug: Cephalexin;   Drug: Cefdinir;   Drug: Clindamycin
Outcome Measure: Healthcare Utilization

These studies may lead to new treatments and are adding insight into Augmentin etiology and treatment.

A major focus of Augmentin research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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