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Bereavement Medical Research Studies

Up-to-date List of Bereavement Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Bereavement Medical Research Studies

Rank Status Study
1 Recruiting A Study of Medication With or Without Psychotherapy for Complicated Grief
Conditions: Complicated Grief;   Bereavement
Interventions: Drug: Citalopram;   Behavioral: Complicated Grief Treatment;   Other: Placebo
Outcome Measures: Change from baseline in Complicated Grief Clinical Global Impression-Improvement (CGI-I) Scale;   Change from baseline in Inventory of Complicated Grief (ICG);   Change from baseline in Work and Social Adjustment Scale (WSAS)
2 Unknown  Long-term Consequences of Bereavement in Children, Adolescents and Young Adults
Condition: Bereavement
Outcome Measures: Hospitalization for affective disorder;   Use of antidepressive medication;   Suicide;   Severe cardiovascular disease;   Education level;   Employment;   Quality of life;   Complicated grief;   PTSD;   Existentiality;   Depressive symptoms;   Relationship functioning;   Support when losing a parent;   Lifestyle (smoking, alcohol, exercise);   Coping
3 Unknown  Parental Bereavement Study Among Couples Coping Traumatic Loss of a Child
Condition: Bereaved Parents
Intervention: Behavioral: Dyadic treatment for parental Bereavement
Outcome Measures: complicated grief symptoms (ICG) and;   marital adjustment. An analysis of change scores is equivalent to a repeated measures analysis comparing only baseline to three-month follow-up.
4 Recruiting Resolving Grief After Spinal Cord Injury
Condition: Spinal Cord Injury
Intervention: Behavioral: The Grief Recovery Method
Outcome Measures: Impact of Event Scale;   Modified Grief Inventory;   The Coping with Health Injuries and Problems
5 Recruiting Iwankapiya-Healing: Historical Trauma Practice and Group IPT for American Indians
Conditions: Depression;   Grief;   PTSD;   Interpersonal Relations
Intervention: Behavioral: HTUG
Outcome Measures: Changes in Hamilton Depression Scale from Baseline;   Changes in the PCL PTSD Checklist;   Changes on the Historical Losses and Historical Losses Associated Symptoms Scales (HLS/HLAS);   Changes in the Inventory of Complicated Grief (ICG);   Inventory of Interpersonal Problems (IIP);   Duke-UNC Functional Support Questionnaire
6 Recruiting Adolescent Loss: The Impact of Loss on Adolescent Oncology Patients
Condition: Adolescent Oncology Patients
Outcome Measures: Number of participants who have experienced the death of a friend or relative by type of loss.;   Descriptive statistics of coping efficacy scores, psychological distress scores, meaning-making scores, and complicated Bereavement scores.;   Number of parents with knowledge of losses experienced by adolescent child.
7 Unknown  A Randomized Controlled Clinical Trial With Orphans and Widows Who Experienced the Rwandan Genocide
Conditions: Posttraumatic Stress Disorder;   Depression;   Prolonged Grief Disorder
Intervention: Behavioral: Narrative Exposure Therapy/Interpersonal Psychotherapy
Outcome Measure: Symptoms of PTSD, depression, prolonged grief disorder
8 Recruiting Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
Conditions: Childhood Traumatic Grief;   Post Traumatic Stress;   Post Traumatic Stress Disorder;   Depressive Symptoms;   Behavioral Problems;   Child Overall Daily Functioning;   Child and Guardian Relationship
Intervention: Behavioral: Trauma-focused Cognitive Behavioral Therapy
Outcome Measures: Posttraumatic Stress Disorder (PTS);   Behavioral Difficulties
9 Recruiting An Interactive Advance Care Planning Intervention to Facilitate a Good Death for Cancer Patients
Condition: End Stage Cancer
Interventions: Behavioral: Interactive advance care planning;   Behavioral: Attention usual care
Outcome Measures: Congruence between preferred and actual EOL care received;   Quality of life for terminally ill cancer patients;   Psychological well-beings for terminally ill cancer patients;   Family depressive symptoms;   Family quality of life;   Bereavement adjustment-Family depressive symptoms;   Bereavement adjustment-complicated grief;   Patient prognosis awareness;   Family prognosis awareness;   EOL care discussions among patients, families, and physicians;   The extent of patient-family agreement on the preferences of EOL care;   Aggressive EOL care treatments
10 Unknown  Needs Assessment for Bereaved Families
Condition: Bereaved Families
Outcome Measure:
11 Recruiting Dignity Talk: Helping Palliative Care Patients and Families Have Important Conversations
Conditions: Palliative Care;   Family;   End of Life Care
Interventions: Behavioral: Dignity Talk;   Behavioral: The Dignity Talk Communication Topics
Outcome Measures: Family communication connectedness Index;   Number of Participants with Adverse Events as a Measure of Safety and Tolerability
12 Recruiting Caregiver Outlook: An Intervention to Improve Caregiving in Serious Illness
Conditions: Heart Failure;   Pulmonary Disease;   Cancer
Interventions: Other: Preparation and life completion;   Other: Attention Control
Outcome Measures: Caregiver Anxiety;   Spirituality;   Depression;   Anticipatory grief;   Patient days at home;   Caregiver burden;   Caregiver completion and preparation;   Prolonged Grief
13 Recruiting VOICE: Values and Options in Care Care
Condition: Cancer
Intervention: Behavioral: Communication training and coaching
Outcome Measures: Aim 1a Improved patient-physician-caregiver communication;   Aim 1 Prolonged grief symptoms (Caregiver Bereavement);   Aim 1b&c Improved Patient-perceived communication;   Aim 2 Patient and Caregiver well-being;   Aim 2 Caregiver Physical Health Outcomes;   Aim 3 Health care utilization
14 Unknown  Using Videos to Facilitate Advance Care Planning for Patients With Heart Failure
Condition: CHF
Intervention: Behavioral: Video decision aid
Outcome Measures: knowledge;   preferences;   decisional conflict;   stability;   concordance of preferences;   advance care planning discussion;   quality of life;   referral to hospice;   place of death;   caregiver Bereavement score
15 Recruiting The Effectiveness of the Liverpool Care Pathway
Conditions: Quality of Life;   Content of Care
Intervention: Other: Liverpool Care Pathway for the Dying Patient
Outcome Measures: The quality of life and quality of care during the last 48 hours of life of patients dying in acute geriatric hospital wards by using the LCP;   Symptom prevalence and symptom burden during the last 48 hours of life of patients dying in acute geriatric hospital wards by using the LCP;   Medications prescribed and administered during the last 48 hours of life of patients dying in acute geriatric hospital wards by using the LCP;   Medical and nursing interventions during the last 48 hours of life of patients dying in acute geriatric hospital wards by using the LCP;   Communication among clinical staff and between clinical staff and patients/relatives during the last 48 hours of life of patients dying in acute geriatric hospital wards by using the LCP;   The level of satisfaction of the relatives with the delivered end-of-life care during the last 48 hours of life of patients dying in acute geriatric hospital wards by using the LCP;   Level of Bereavement of the relatives of patients who died in acute geriatric hospital wards by using the LCP
16 Recruiting Pilot Study of Interpersonal and Social Rhythm Therapy for Subthreshold Bipolar
Condition: Bipolar Disorder NOS
Intervention: Other: Interpersonal and social rhythm therapy
Outcome Measure: Depression severity
17 Unknown  Prevention of Depression in Spouses of People With Cognitive Impairment
Condition: Depression
Interventions: Behavioral: Problem-solving therapy;   Behavioral: Nutritional education program
Outcome Measures: Depressive symptoms;   Anxiety symptoms;   Objective caregiver burden;   Subjective caregiver burden;   Household management and care giving responsibilities;   Coping abilities;   Quality of the marital relationship;   Social support;   Anticipatory grief;   Social problem solving abilities;   Quality of Life
18 Recruiting Cognitive Therapy for Suicidal Older Men
Condition: Suicide, Attempted
Interventions: Behavioral: Cognitive Therapy;   Behavioral: Enhanced Usual Care
Outcome Measures: Change in baseline suicidal ideation;   depression;   hopelessness;   quality of life;   social problem solving skills;   complicated grief;   reasons for living and dying;   perceived social support;   Cognitive Executive Functioning
19 Not yet recruiting The Safety and Effectiveness of Gatekeeper Training in First Nations Communities
Condition: Applied Suicide Intervention Skills Training
Intervention: Other: Applied Suicide Intervention Skills Training
Outcome Measures: Number of people asked about suicidal thoughts;   Self-perceived Confidence in Helping a Suicidal Individual;   Self-perceived Skill in Helping a Suicidal Individual;   Self-perceived Knowledge About Suicide;   Self-perceived Preparedness;   Suicidal ideation in past 6 months;   Suicidal Ideation in Past 2 Days;   Suicide Attempt in Past 2 Days;   Suicide Attempt in past 6 months;   Two-item Conjoint Screen (TICS) for alcohol and drugs;   Patient Health Questionnaire (PHQ-9);   Lifetime Suicidal Ideation at Baseline;   Lifetime Suicide Attempt at Baseline;   Complicated grief at baseline;   Number of respondents who asked someone about suicidal thoughts in past 6 months;   How often asked a person about suicidal thoughts;   Number of suicidal people identified;   Number of suicidal people treated;   Number of respondents who did not ask someone about suicidal thoughts in past 6 months;   Suicide attitudes
20 Recruiting Default Options in Advance Directives
Condition: This Study Will Focus on Advance Care Planning Among Patients With Life-limiting Illnesses
Interventions: Behavioral: Life-extension default advance directive;   Behavioral: Comfort default advance directive
Outcome Measures: Hospital free days;   Hospital and ICU admissions;   Costs of care;   Hospice utilization;   Choices to receive 4 potentially life-sustaining interventions, and the concordance of these choices with whether the interventions were actually received;   Choices regarding post-hospitalization care, and the concordance of these choices with the care actually received;   Decision regret;   Decision satisfaction;   Quality of Life using the McGill Quality of Life (MQOL) instrument.;   Surrogates' Perception of the quality of death and dying;   Post-traumatic stress in surrogates;   Complicated grief among surrogates

These studies may lead to new treatments and are adding insight into Bereavement etiology and treatment.

A major focus of Bereavement research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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