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Bezalip Medical Research Studies

Up-to-date List of Bezalip Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Bezalip Medical Research Studies

Rank Status Study
1 Recruiting Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis
Condition: PBC
Interventions: Drug: Bezafibrate;   Drug: placebo
Outcome Measures: Percentage of patients with complete biochemical response.;   Percentage of patients having biological or clinical adverse reaction.;   Percentage of patients having complete biochemical response.;   Evolution of the pruritus.;   Assessment of the fatigue and the quality of life.;   Evolution of liver fibrosis surrogate markers.;   Evolution of the portal hypertension markers.;   Histological evolution: Histopathological examination of biological sample before enrolment and at the end of the study.;   Evolution of the biological markers of the hepatic function or being in the usual prognostic scores (Mayo, Child, MELD).;   Survival without transplantation and hepatic impairment.
2 Unknown  Bezafibrate Trial in CPT2 Deficiency
Condition: Carnitine Palmitoyl Transferase 2 Deficiency
Intervention: Drug: bezafibrate (drug)
Outcome Measures: Rate of 3H-palmitate oxidation in the patients'lymphocytes and skeletal muscle;   Rate of CPT2 enzymatic activity in the patients'lymphocytes and skeletal muscle;   Rate of palmitoyl-L-carnitine oxidation in the patients' skeletal muscle;   Steady-state amount of CPT2 mRNA in the patients'skeletal muscle

These studies may lead to new treatments and are adding insight into Bezalip etiology and treatment.

A major focus of Bezalip research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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