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Boots Medical Research Studies

Up-to-date List of Boots Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Boots Medical Research Studies

Rank Status Study
1 Not yet recruiting Rehabilitation Boot Camp: Intensive Balance and Mobility Therapy for People With Acquired Brain Injury
Condition: Brain Injuries
Intervention: Behavioral: Boot Camp Balance Training
Outcome Measures: Change from baseline measure of Dual Task Cost of a visual cognitive task on stationery balance;   Change from baseline measure in time (seconds) to perform Five Times Sit to Stand Test;   Change in score from baseline measure in Chedoke McMaster Stroke Assessment Activity Scale;   Change from baseline measure of the Sway Path Length during The Modified Clinical Test of Integration in Balance (mCTSIB);   Change in distance walked (meters) from baseline measure in the Two Minute Walk Test (2 MWT);   Change in score from baseline measure in the Participation Assessment with Recombined Tools - Objective 17 (PART-O 17)
2 Unknown  Developing a Diabetic Foot Ulcer Protocol
Condition: Diabetic Foot Ulcers
Interventions: Other: type of footwear;   Other: collagen dressing with and without silver
Outcome Measures: decrease in size of wound;   non-healing wound
3 Unknown  Preventive Effect of Proprioceptive Stimulation on Muscle Atrophy
Condition: Knee Arthritis
Intervention: Procedure: proprioceptive stimulation
Outcome Measures: The Isokinetic Maximal Voluntary strenght of the plantar floxors of the ankle. The outcome measure is assessed using an isokinetic strength assesment device (CON-TREX , CVM-AG, Switzerland);   Volume of the Soleus muscle
4 Not yet recruiting Outcome of Rehabilitation Following Internally Fixed Ankle Fractures
Conditions: Ankle Fractures;   Fracture
Interventions: Device: Aircast XP Walker boot;   Device: Plaster Immobilisation
Outcome Measure: MOxFQ score (Manchester and Oxford Foot Questionaire
5 Recruiting Combined Randomised and Observational Study of Type B Ankle Fracture Treatment
Condition: Ankle Fractures
Interventions: Procedure: Open reduction internal fixation of the ankle;   Procedure: Non Operative
Outcome Measures: American Academy of Orthopaedic Surgeons (AAOS) Foot and Ankle Questionnaire;   Short Form (SF)-12v2;   Complications
6 Recruiting Non-operative Treatment of Acute Achilles Tendon Rupture: Early Controlled Mobilization Compared With Immobilization
Conditions: Achilles Tendon Rupture;   Deep Vein Thrombosis
Intervention: Procedure: Controlled early mobilization
Outcome Measures: Achilles tendon Total Rupture Score;   Heel-rise work test;   Ultrasound length measure;   Cost effectiveness analysis
7 Recruiting Hard-soled Shoe Versus Short Leg Walking Cast for a Fifth Metatarsal Avulsion Fracture: A Randomized Multicenter Noninferiority Trial
Conditions: Metatarsal Fracture;   Treatment
Interventions: Procedure: Protected weightbearing in a hard-soled shoe;   Procedure: Protected weightbearing in a short leg walking cast
Outcome Measures: 100mm visual analogue scale (VAS);   Time to return to preinjury activity;   patients' subjective satisfactions
8 Recruiting Clinical Implications of Genetic Variations of Venous Stasis Ulceration
Condition: Venous Ulcers
Intervention: Procedure: Blood Draw
Outcome Measures: Ulcer healing;   Ulcer recurrence;   Analysis of genetic variation in concert with ulcer healing, time to healing and recurrence
9 Unknown  Early Weightbearing and Mobilization Versus Non-Weightbearing and Mobilization in Unstable Ankle Fractures
Condition: Ankle Injuries
Interventions: Behavioral: Early weight-bearing and range of motion exercises;   Behavioral: non-weight bearing, no range of motion
Outcome Measures: Return to work;   Functional outcome and event rate;   Return to work and functional outcome
10 Not yet recruiting Farming, Personal Protective Equipment, Nepal
Condition: Organophosphate Poisoning
Intervention: Device: LAPPE (locally adapted personal protective equipment)
Outcome Measures: Plasma Cholinesterase;   Acute Organophosphate Poisoning Symptoms
11 Unknown  Cooling Lower Leg Skin to Prevent Venous Leg Ulcers in Patients With Poor Vein Circulation
Conditions: Venous Disease;   Venous Vascular Diseases and Syndromes;   Venous Insufficiency;   Venous Ulcers
Interventions: Procedure: Cryotherapy: Cooling gel wrap;   Procedure: Usual care
Outcome Measures: Skin blood flow;   Incidence of venous leg ulcers that develop during the study;   Quality of life;   Pain;   Skin temperature
12 Recruiting Validation of a New Method of Limb Volumetry
Conditions: Edema;   Chronic Venous Insufficiency;   Lymphedema
Intervention:
Outcome Measure: Difference between limb volume measured
13 Recruiting Screening Platform for Clinical Trials in Advanced Colorectal Cancer
Conditions: Colorectal Cancer;   Advanced Colorectal Cancer
Intervention: Genetic: Tumour markers testing
Outcome Measure: Tumour markers assessment
14 Recruiting Study of KRN23, a Humanized Anti-FGF23 Monoclonal Antibody, in Pediatric Subjects With X-linked Hypophosphatemia (XLH)
Condition: X-linked Hypophosphatemia
Intervention: Drug: KRN23
Outcome Measures: Serum Phosphorus levels;   Incidence, frequency, and severity of adverse events and serious adverse events

These studies may lead to new treatments and are adding insight into Boots etiology and treatment.

A major focus of Boots research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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