PatientsVille.com Logo


Bradycardia Medical Research Studies

Up-to-date List of Bradycardia Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Bradycardia Medical Research Studies

Rank Status Study
1 Recruiting ENHANCE - Efficacy of the Presence of Right Ventricular Apical Pacing Induced Ventricular Dyssynchrony as a Guiding Parameter for Biventricular Pacing in Patients With Bradycardia and Normal Ejection Fraction
Condition: Bradycardia
Intervention: Device: CRT
Outcome Measures: Left ventricular ejection fraction (LVEF);   Left ventricular end-systolic volume
2 Recruiting Effect of the Side of Interscalene Block on Bradycardia and Hypotension in Beach Chair Position
Conditions: Shoulder Surgery;   Beach Chair Position;   Interscalene Block;   Hypotension;   Bradycardia;   Autonomic Nervous System
Interventions: Other: Left interscalene block;   Other: Right interscalene block
Outcome Measure: Interscalene block and beach chair positioning
3 Recruiting AV Delay Optimization vs. Intrinsic Conduction in Pacemaker Patients With Long PR Intervals
Conditions: Atrioventricular Block;   Sick Sinus Syndrome;   Symptomatic Bradycardia
Interventions: Device: Long, fixed AV delay;   Device: Short, optimized AV delay
Outcome Measures: Change in cardiac output determined by echocardiography;   Changes in functional status determined by 6 minute walk.;   Changes in sense of well being as determined by Short Form - 36 Medical Outcomes Study Questionnaire
4 Recruiting Safety and the Effects of Isolated Left Ventricular Pacing in Patients With Bradyarrhythmias
Conditions: Bradyarrhythmias;   Arrhythmias;   Atrioventricular Block;   Ventricular Dysfunction;   Cardiovascular Disease
Interventions: Device: Left ventricular pacing through coronary sinus tributaries (Attain StarFix);   Device: Right ventricular pacing (Medtronic)
Outcome Measures: Surgical success;   Echocardiographic and Clinical composite
5 Unknown  Identify the Genes Polymorphisms Related to Non-familial Bradyarrhythmia
Condition: Bradyarrhythmia
Outcome Measure:
6 Recruiting Autonomic Nervous System Activity and Oculocardiac Reflex.
Condition: Bradycardia During Pulling of Eyeball
Outcome Measure: oculocardiac reflex occurence in relation to autonomic system activity
7 Recruiting Chest Compression and Sustained Inflation
Condition: Newborn Infants Having Asystole or Bradycardia at Birth
Interventions: Procedure: CC+SI;   Procedure: Control
Outcome Measure: Time needed to achieve Return of Spontaneous Circulation
8 Not yet recruiting Safety and Efficacy of St Jude Medical ( SJM ) MRI Conditional Pacing System Undergoing Cardiac MRI Scan
Condition: Bradycardia
Interventions: Procedure: Cardiac MRI scan;   Device: SJM MRI conditional pacing system implant
Outcome Measures: Freedom from MRI scan-related complications;   Change in right atrial/ventricular capture threshold @0.5ms before and 1 month after the MRI scan;   Change in right atrial/ventricular sensing amplitude before and 1 month after the MRI scan
9 Not yet recruiting Eluna Family / Sentus BP Master Study
Conditions: Bradycardia;   Heart Failure
Interventions: Device: Eluna pacemaker family;   Device: Sentus BP lead
Outcome Measures: Eluna pacemaker family: Serious Adverse Device Effect (SADE) - free rate;   Sentus BP lead: Serious Adverse Device Effect (SADE) - free rate
10 Recruiting Study of Erythromycin in GER-Associated Apnea of the Newborn
Conditions: Gastroesophageal Reflux;   Apnea;   Bradycardia
Interventions: Drug: Erythromycin;   Device: Multi-channel intra-luminal impedance (MII) pH monitoring;   Drug: Placebo (D5W)
Outcome Measures: Reflux Impedance events (both acidic and non-acidic) as recorded by Multichannel Intraluminal (MII) pH Impedance;   ABD events per Physiologic Monitoring Database;   ABD events recorded by nursing
11 Unknown  Atropine Versus no Atropine for Neonatal Rapid Sequence Intubation
Conditions: Bradycardia;   Hypoxemia
Interventions: Drug: atropine;   Drug: Placebo
Outcome Measures: Heart rate less than 80 BPM and oxygen saturation less than 80%;   Heart rate < 100 BPM;   Oxygen saturation < 85%;   Duration of intubation attempts;   Number of intubation attempts;   Lowest heart rate after premedication;   Lowest oxygen saturation after premedication
12 Recruiting System Longevity Study: Evaluating Reliability and Performance of Medtronic Cardiac Therapy Products
Conditions: Arrhythmia;   Bradycardia;   Heart Failure;   Sinus Tachycardia
Outcome Measure: Lead related complications for each lead model.
13 Not yet recruiting Evaluation of Closed-loop TIVA Propofol, Sufentanil and Ketamine Guided by BIS Monitor
Conditions: Acute Cholecystitis;   Chronic Cholecystitis
Interventions: Procedure: TIVA - Hypotension;   Procedure: TIVA - Hypertension;   Procedure: TIVA - Bradycardia;   Procedure: TIVA - Tachycardia;   Procedure: INH - Hypotension;   Procedure: INH - Hypertension;   Procedure: INH - Bradycardia;   Procedure: INH - Tachycardia
Outcome Measures: Time to discharge from PACU;   Post operative Nausea and/or vomiting;   Visual Analog Scale Pain score;   ALDRETE Sedation Score;   Time to extubation
14 Recruiting Impact of Swaddle Blanket on Gastroesophageal Reflux
Conditions: Gastroesophageal Reflux;   Apnea;   Bradycardia;   Oxygen Desaturations
Intervention: Other: Swaddle Blanket
Outcome Measures: pH;   apnea
15 Not yet recruiting Six Lead Identification of Atrial Fibrillation
Conditions: Atrial Fibrillation;   Atrial Flutter;   Bradycardia;   Tachycardia;   Tachycardia, Supraventricular
Intervention: Device: RhythmPadGP
Outcome Measures: Number of participants with a diagnosis of Atrial Fibrillation;   Number of participants with a diagnosis of atrial flutter;   Number of participants with a diagnosis of tachycardia (heart rate greater the 100 beats per minute);   Number of participants with a diagnosis of Bradycardia (heart rate less then 50 beats per minute);   Accurate diagnosis of supraventricular tachycardia;   Number of participants with a diagnosis of atrial or ventricular ectopy
16 Unknown  Choosing the Right Pacing Mode in Heart Failure - The CHOICE Trial
Condition: Heart Failure
Interventions: Device: Bi Ventricular Pacing;   Device: Right Ventricular Pacing
Outcome Measures: 6 minute hall walk test;   Endothelial Function;   Cardiac Output
17 Recruiting Analgesia Nociception Index Guided Remifentanil Administration During Propofol Anesthesia for Laparoscopic Surgery
Condition: General Anesthesia
Interventions: Procedure: ANI guided remifentanil;   Procedure: ANI blind arm
Outcome Measures: Proportion of patients presenting at least once with hemodynamic reactivity, hypotension or Bradycardia;   total administered remifentanil;   number of target changes;   morphine sulfate total administration after end of surgery;   Visual Analog Scale evaluation of pain after surgery;   ANI measure during surgery;   number of Bradycardia and hypotension;   total administered dose of ephedrine
18 Recruiting Clinical Outcome of Pacemaker paTIents According to Pacing Modality and Primary INDications OPTI-MIND 2
Condition: Bradyarrhythmia
Outcome Measures: Combined event rate of all-cause mortality, cardiovascular hospitalizations and atrial fibrillation at 2 years in a specific Brady population implanted with BSC PM devices equipped with RYHTMIQ feature;   Combined event rate of all-cause mortality, cardiovascular hospitalizations and atrial fibrillation at 2 years stratified per patient characteristics.
19 Unknown  Left Ventricular Pacing to Avoid Cardiac Enlargement Study
Conditions: Complete Atrioventricular Block;   Sick Sinus Syndrome
Interventions: Device: LV pacing;   Device: RV pacing
Outcome Measures: Left ventricular ejection fraction (%) at 12 months;   Left ventricular end-systolic volume (ml) at 12 months;   Left ventricular end-diastolic volume (ml) at 12 months;   Maximal oxygen uptake (ml/kg min) at 12 months
20 Recruiting Randomized Clinical Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients.
Conditions: Hypertension, Pregnancy Induced;   Hydralazine Adverse Reaction;   Pre-eclampsia;   Pre-eclampsia Superimposed Pre-existing Hypertension
Interventions: Drug: Labetalol;   Drug: Hydralazine
Outcome Measures: Sever persistent hypertension;   Efficacy (Reduction in blood pressure below thresholds).;   Maternal tachycardia;   Bradycardia;   Bronchospasm;   Maternal hypotension

These studies may lead to new treatments and are adding insight into Bradycardia etiology and treatment.

A major focus of Bradycardia research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

Discuss Bradycardia