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Buspar Medical Research Studies

Up-to-date List of Buspar Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Buspar Medical Research Studies

Rank Status Study
1 Recruiting Buspirone, Stress, and Attentional Bias to Marijuana Cues
Condition: Cannabis Use Disorder
Interventions: Drug: Buspirone;   Drug: Placebo
Outcome Measures: attentional bias;   stress
2 Recruiting An Open-Label Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum Disorders
Conditions: Autism Spectrum Disorders;   Anxiety
Intervention: Drug: Buspirone
Outcome Measures: Reduction in Pediatric Anxiety Rating Scale (PARS) score;   Clinical Global Impression-Anxiety (CGI-Anxiety) Improvement Score
3 Recruiting Psychopharmacology for Cocaine Dependence - Buspirone
Condition: Cocaine Dependence
Intervention: Drug: Buspirone
Outcome Measures: Cocaine-Stroop;   Risky decision making;   ARCI;   POMS;   DEQ;   VAS;   cardiovascular
4 Recruiting Impact of Buspirone Maintenance on the Reinforcing Effects of Cocaine
Condition: Cocaine Use Disorders
Intervention: Drug: Buspirone
Outcome Measures: Reinforcing Effects;   Subjective Effects;   Physiological and Side Effects;   Performance Effects
5 Recruiting Buspirone as a Candidate Medication for Methamphetamine Abuse
Conditions: Methamphetamine Dependence;   Methamphetamine Abuse
Intervention: Drug: Methamphetamine
Outcome Measures: Reinforcing Effects of Methamphetamine During Buspirone Treatment;   Reinforcing Effects of Methamphetamine During Placebo Treatment;   Subjective Effects;   Physiological and Side Effects
6 Recruiting Buspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and Aggression
Condition: Traumatic Brain Injury
Interventions: Drug: Buspirone;   Drug: Placebo
Outcome Measures: Neuropsychiatric Inventory-Irritability Domain;   Neuropsychiatric Inventory-Aggression Domain;   Neuropsychiatric Inventory-Distress Irritability Domain;   Neuropsychiatric Inventory-Distress Aggression Domain;   St. Andrews-Swansea Neurobehavioural Outcome Scale;   Personal Health Questionnaire;   Traumatic Brain Injury-Quality of Life Anger;   Global Impressions of Change;   Clinical Global Impressions;   Aggression and Irritability Impact Measure;   Generalized Anxiety Disorder
7 Recruiting Buspirone Therapy for Localized Epilepsy
Conditions: Seizures;   Epilepsy;   Partial Epilepsy;   Depression
Intervention: Drug: Buspirone
Outcome Measures: Difference in seizure rate between the baseline and buspirone periods.;   Neuropsychological and mood indices before and three months after starting after
8 Unknown  Effects of Buspar on Depressive Symptom Improvement and Neuroprotection in Patients With Anxiety Disorder
Condition: Anxiety Disorder
Interventions: Drug: buspirone+alprazolam;   Drug: alprazolam;   Other: healthy controls
Outcome Measures: change from baseline in depressive symptom scores at 8 weeks;   change from baseline in depressive symptom scores at 4 weeks;   change from baseline in depressive symptom scores at 1 week;   change from baseline in anxiety symptom scores at 8 weeks;   change from baseline in anxiety symptom scores at 4 weeks;   change from baseline in anxiety symptom scores at 1 week;   changes from baseline in brain structure, function, and biochemical metabolism, analyzed using the computational approach;   number of participants with adverse events
9 Recruiting Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury
Condition: Spinal Cord Injury
Intervention: Drug: SPINALON (buspirone + levodopa + cardidopa)
Outcome Measures: Heart rate;   Tolerability of common AEs;   Pharmacokinetics;   Blood pressure;   Respiration rate;   Oxygen saturation;   Temperature;   Change in hematology and biochemistry laboratory parameters;   Occurrence of rhythmic leg EMGs
10 Recruiting Cooling Plus Best Medical Treatment Versus Best Medical Treatment Alone for Acute Ischaemic Stroke
Condition: Acute Ischemic Stroke
Interventions: Device: Hypothermia;   Drug: Buspirone;   Drug: Pethidine
Outcome Measures: modified Rankin scale;   Mortality;   Neurological outcome;   Quality of life;   Cerebral infarct size;   Safety of systemic cooling;   Tolerability of systemic cooling
11 Unknown  Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure
Condition: Posttraumatic Stress Disorder, Combat-related
Interventions: Drug: Fluoxetine;   Drug: Placebo
Outcome Measures: Clinician Administered PTSD Scale;   PTSD Symptom Checklist

These studies may lead to new treatments and are adding insight into Buspar etiology and treatment.

A major focus of Buspar research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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