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Cabaseril Medical Research Studies

Up-to-date List of Cabaseril Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Cabaseril Medical Research Studies

Rank Status Study
1 Unknown  Efficacy of Rapid Escalation of Cabergoline in Comparison to Conventional Dosing in Prolactin Secreting Macroadenomas.
Condition: Macroprolactinoma
Interventions: Drug: Cabergoline;   Drug: cabergoline
Outcome Measures: Normoprolactinemia;   Duration for resolution of Hypogonadism
2 Recruiting Cabergoline in Metastatic Breast Cancer
Conditions: Recurrent Breast Cancer;   Stage IV Breast Cancer
Intervention: Drug: cabergoline
Outcome Measures: Determining overall response using imaging scans;   Survival Rates;   Treatment toxicity as measured by adverse events experienced while on treatment;   Change in imaging measurements at baseline and after 2 cycles;   Change in prolactin receptor expression measurements at baseline and after 1 cycle;   Evaluate biomarkers and correlate with response to therapy
3 Recruiting Prevention of Ovarian Hyperstimulation Syndrome
Condition: Infertility
Interventions: Drug: Diosmin;   Drug: Cabergoline
Outcome Measures: ovarian hyperstimulation syndrome (OHSS);   pregnancy rate
4 Unknown  Compare the Efficacy of Human Albumin With Cabergoline to Prevent Ovarian Hyper Stimulation in Assisted Reproductive Technology (ART) Program
Condition: Ovarian Hyperstimulation Syndrome
Interventions: Drug: Cabergoline;   Drug: Control
Outcome Measures: Percentage and severity of OHSS in two groups;   Efficacy and safety of cabergoline and albumin
5 Unknown  Expression Profile of Somatostatin Receptors and Dopamine Receptor 2 in Non-functioning Pituitary Adenomas and Resistant Prolactinomas: Correlation With in Vivo Response to Pasireotide and Cabergoline
Conditions: Non-functioning Pituitary Adenomas;   Prolactinomas
Interventions: Drug: Pasireotide;   Drug: cabergoline
Outcome Measures: Tumor volume reduction;   Prolactin levels normalization
6 Recruiting Study of the Efficacy and Safety of Pasireotide s.c. +/- Cabergoline in Patients With Cushing's Disease
Condition: Cushing's Disease
Interventions: Drug: Pasireotide;   Drug: Cabergoline
Outcome Measures: mUFC;   Percentage change in mUFC from baseline to study end at each scheduled visit when UFC is measured;   Proportion of patients attain mUFC ≤ 1.0 x ULN as assessed at each scheduled visit when UFC is measured;   Proportion of patients who attain mUFC ≤ 1.0 x ULN or have at least 50% reduction from baseline in mUFC as assessed at each scheduled visit when UFC is measured;   Duration of controlled or partially controlled response;   Change from baseline in plasma ACTH and serum cortisol over time;   Ctrough at baseline;   Ctrough at week 8;   Ctrough;   Cmax at baseline;   Cmax at week 8;   Cmax;   Toxicity will be assessed using NCI-CTCAE v.4 and for laboratory assessments
7 Unknown  Cabergoline Effect on Blood Sugar in Type 2 Diabetics
Condition: Diabetes Type 2
Intervention: Drug: Cabergoline
Outcome Measures: FBS (fasting blood sugar);   HbA1C
8 Recruiting Cabergoline Versus Coasting in Gonadotropin Releasing Hormone(GnRH)Agonist Protocol in Intracytoplasmic Sperm Injection (ICSI) to Prevent Ovarian Hyperstimulation Syndrome (OHSS)
Condition: OHSS
Intervention: Procedure: ICSI
Outcome Measures: Rate and degree of OHSS (composite outcome);   Number of oocytes
9 Recruiting Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After Treatment
Conditions: Hyperprolactinemia;   Insulin Resistance
Intervention: Other: Cabergoline
Outcome Measures: Insulin sensitivity;   QoL, body composition, intrahepatic and intramyocellular fat, substrate metabolism, glucose tolerance
10 Unknown  Turmeric Effect on Reduction of Serum Prolactin and Related Hormonal Change and Adenoma Size in Prolactinoma Patients
Condition: Hyperprolactinoma
Intervention: Drug: Curcumin
Outcome Measures: serum prolactin level;   change in LH,FSH and estradiol from baseline

These studies may lead to new treatments and are adding insight into Cabaseril etiology and treatment.

A major focus of Cabaseril research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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