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Caplet Medical Research Studies

Up-to-date List of Caplet Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Caplet Medical Research Studies

Rank Status Study
1 Recruiting Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS)
Condition: Polycystic Ovary Syndrome (PCOS)
Interventions: Drug: DLBS3233;   Drug: Metformin XR;   Drug: Placebo caplet of Metformin XR;   Drug: Placebo capsule of DLBS3233
Outcome Measures: HOMA-IR reduction;   Response rate: number of subjects having normalization of menses;   Response rate: pregnancy;   Reduction of BMI;   Change of body fat composition;   Change of waist circumference;   Reduction of S/A ratio;   Reduction of free testosterone level (calculated);   Change of luteinizing hormone (LH) level;   Change of luteinizing hormone (LH) / follicle stimulating hormone (FSH) ratio;   Change of Ferriman-Gallwey Score;   Improvement of glucose tolerance;   Fasting insulin level reduction;   Lipid profile improvement;   Vital signs;   Electrocardiography (ECG);   Liver function;   Renal function;   Number of adverse events and subjects with events;   Ovulation rate;   Change of Anti Mullerian Hormone (AMH) level
2 Recruiting A 6 Week Randomized Study of MG01CI 1400 mg Compared With Placebo in Adults With ADHD (Adults With Attention Deficit/Hyperactivity )
Conditions: ADHD;   Predominantly Inattentive ADHD (PI-ADHD)
Interventions: Drug: MG01CI (1400 mg);   Drug: placebo
Outcome Measures: Total ADHD symptom score with adult prompts of the Conners Adult ADHD Rating Scale:O-SV in ADHD adults;   Total ADHD symptom score with adult prompts of the CAARS Inv, in adults with predominantly inattentive ADHD (PI-ADHD);   Efficacy evaluation on the basis of improvement from baseline in CGI-I AND CGI-S;   Safety evaluation of treatment on the basis of adverse events number;   Population PK (PopPK);   • Efficacy evaluation on the basis of improvement from baseline in ASRS-Self - expanded version;   Efficacy evaluation on the basis of improvement from baseline in AAQoL total score and 4 sub-scores (Life Productivity, Psychological Health, Relationships and Life outlook);   Efficacy evaluation on the basis of improvement from baseline in BRIEF-A, Global Executive Composite, Behavioral Regulation Index and Metacognition Index
3 Recruiting Pharmacodynamic Evaluation of PL2200 Versus Enteric-Coated Aspirin in Diabetic Patients
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: PL2200 Aspirin Capsules;   Drug: Enteric-coated aspirin Caplets
Outcome Measures: Pharmacodynamic bioequivalence;   Pharmacokinetic bioequivalence;   Safety and tolerability
4 Recruiting Clinical Study to Evaluate Efficacy of New Paracetamol Formulation Compared to Ibuprofen in Headache
Condition: Headache, Tension-Type
Interventions: Drug: Paracetamol and Caffeine;   Drug: Ibuprofen;   Other: Placebo
Outcome Measures: Sum of pain intensity difference (SPID) of experimental formulation vs placebo;   SPID of other treatments;   Time to perceptible headache relief;   Time to meaningful headache relief;   Total pain relief (TOTPAR);   Sum of TOTPAR and SPID (SPRID);   Global Evaluation of Response to Treatment;   Rate of rescue medication;   Time to rescue medication
5 Not yet recruiting Safety and Efficacy of IMM 124-E for Patients With Severe Alcoholic Hepatitis
Condition: Hepatitis, Alcoholic
Interventions: Drug: IMM 124-E (Hyperimmune Bovine Colostrum);   Drug: Placebo
Outcome Measures: Greater decrease in mean circulating endotoxin levels in those receiving Steroids+ Imm 124-E compared to steroids + placebo;   Microbiome-metagenomic-immunologic data;   Efficacy related outcomes;   Safety Related endpoints
6 Not yet recruiting PCOS Treatment Using DLBS3233, Metformin, and Combination of Both
Conditions: Polycystic Ovary Syndrome (PCOS);   Insulin Resistance
Interventions: Drug: DLBS3233;   Drug: Metformin XR;   Drug: Placebo metformin;   Drug: Placebo DLBS3233
Outcome Measures: HOMA-IR reduction;   Lipid profile improvement;   Improvement of glucose tolerance;   Reduction of BMI;   Change of waist circumference;   Response rate: presence of ovulation;   Change of endometrium thickness;   Improvement of S/A ratio;   Response rate: normalization of menses (ovulatory cycle);   Response rate: pregnancy;   Improvement in Ferriman-Gallwey Score;   Reduction of free testosterone level;   Change of luteinizing hormone (LH) level;   Change of luteinizing hormone (LH) / follicle stimulating hormone (FSH) ratio;   Vital signs;   Electrocardiography (ECG);   Liver function;   Renal function;   Number of adverse events and subjects with events
7 Unknown  Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2?
Conditions: HIV Infections;   Herpes Simplex
Interventions: Drug: Valacyclovir;   Drug: Placebo
Outcome Measures: Percentage activated CD8+ T-cells;   Inflammatory markers;   CD4 cell count;   Virologic blips;   Drug-related adverse events;   HSV reactivations;   Acyclovir-resistant HSV
8 Recruiting Relative Bioavailability Study of One Amlodipine 10mg Tablet and One Rosuvastatin 20mg Tablet to Two Fixed Dose Combinations of Amlodipine (10mg) and Rosuvastatin (20mg) in Healthy Subjects Under Fasting Conditions
Condition: Hypertension
Interventions: Drug: Amlodipine+Rosuvastatin;   Drug: GSK3074477 FDC - 1;   Drug: GSK3074477 FDC - 2
Outcome Measures: Plasma pharmacokinetics (PK) parameters of amlodipine and rosuvastatin following single dose administration;   Additional PK parameters of amlodipine and rosuvastatin following single dose administration;   Safety as assessed by adverse events;   Safety as assessed by vital signs;   Safety as assessed by clinical laboratory safety data;   Safety as assessed by Electrocardiogram (ECG) parameters
9 Not yet recruiting Resveratrol: a Potential Anti-remodeling Agent in Heart Failure, From Bench to Bedside
Condition: Non-ischemic Cardiomyopathy
Interventions: Other: Resveratrol;   Other: Placebo
Outcome Measures: Quality of life;   Cardiac Function;   Oxidative Stress;   Total Antioxidant Status;   Inflammatory Marker Measurements;   Nitric Oxide Determination

These studies may lead to new treatments and are adding insight into Caplet etiology and treatment.

A major focus of Caplet research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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