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Cardio Medical Research Studies

Up-to-date List of Cardio Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Cardio Medical Research Studies

Rank Status Study
1 Unknown  Rapid Stress/Rest Single-Day Tc-99m Sestamibi Myocardial Single Photon Emission Computed Tomography
Condition: Coronary Artery Disease
Intervention: Other: myocardial perfusion SPECT
Outcome Measures: Myocardial perfusion SPECT image quality;   rest/stress myocardial count density ratio
2 Unknown  The Comparison of the Necessity of Repeat Myocardial Perfusion SPECT Studies Between Tc-99m Tetro and Tc-99m Mibi
Condition: Myocardial Ischemia
Outcome Measures: Number of studies repeated.;   Number of studies that should have been repeated
3 Recruiting Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue
Condition: Uptake of Sestamibi Tracer
Interventions: Dietary Supplement: Meal;   Other: Exercise;   Radiation: Sestamibi;   Drug: Caffeine Tablet;   Other: External Heating
Outcome Measure: Uptake of this radiopharmaceutical in breast tissue
4 Unknown  Investigation of High Resolution Nuclear Breast Imaging Camera (MBI) in Patients Administered Tc-99m Sestamibi (ROSE)
Condition: Breast Lesions
Outcome Measure:
5 Recruiting Anti-3-[18F]FACBC Imaging of Parathyroid Adenomas
Condition: Parathyroid Disease
Intervention: Drug: FACBC
Outcome Measures: Correlate uptake of anti-3-[18F]FACBC to surgical findings of parathyroid adenomas;   Measure uptake mechanisms of anti-3-[18F]FACBC in parathyroid adenomas
6 Recruiting Efficacy and Safety of Ad5FGF-4 for Myocardial Ischemia in Patients With Stable Angina Due to Coronary Artery Disease
Condition: Angina, Stable
Intervention: Genetic: Alferminogene tadenovec
Outcome Measures: Change in reversible perfusion defect size (RPDS) as measured by adenosine triphosphate (ATP) single-photon emission computed tomography with technetium-99m sestamibi (SPECT);   Change in angina frequency and nitroglycerin use;   Change in quality of life using the Seattle Angina Questionnaire;   Change in patient functional class using CCS anginal classification;   Safety of Ad5FGF-4 as assessed by adverse events and clinical laboratory testing;   Long-term safety of Ad5FGF-4 as assessed by serious adverse events
7 Recruiting Sodium Nitrite in Acute Myocardial Infarction
Condition: Acute Myocardial Infarction
Intervention: Drug: Sodium Nitrite
Outcome Measures: Primary efficacy outcome is a to determine whether sodium nitrite safely reduces infarct size normalized for the ischemia area at risk as determined by paired single-photon computed tomography studies with technetium Tc99m sestamibi.;   Left ventricular volumes, ejection fraction, and infarct size by magnetic resonance imaging.
8 Recruiting Comparison of Rubidium PET and SPECT With CZT Crystals for Detection of Myocardial Ischemia in Overweighed Patients and Women
Condition: Myocardial Ischemia
Intervention: Radiation: Rubidium PET
Outcome Measures: Myocardial ischemia;   Size and intensity of myocardial ischemia
9 Not yet recruiting Can Hypothermia be Incorporated Into Primary Angioplasty for Heart Attack?
Condition: ST-Elevation Myocardial Infarction
Intervention: Device: Life Recovery Systems ThermoSuit
Outcome Measures: Feasibility of use of cooling device as determined by ability and time to achieve target temperature and ease of maintaining temperature in therapeutic range (32 to 34°C) for three hours following removal of patient from ThermoSuit.;   Primary safety endpoint: composite of serious adverse events including: death, re-infarction, ischemia-driven TVR, pneumonia, sepsis, arrhythmia, bleeding, stroke, and renal failure.;   Major adverse cardiac events at 30 days as defined by death or non-fatal re-infarction. c. Ischemia-driven target vessel revascularization.;   Myocardial infarct size at 30 days as measured by 99mTc-sestamibi SPECT imaging.;   Safety, including all-cause mortality, cardiac, vascular, and hematological complications.;   Adverse events associated with conscious sedation.;   Arterial blood pressure and heart rate every 5 minutes from the baseline just before the start of cooling until 30 minutes after cooling has started.;   Door to balloon time.
10 Unknown  Input of C11-Choline PET/CT in Localization of Parathyroid Adenoma
Condition: Hyperparathyroidism
Intervention: Procedure: C11-Choline PET/CT
Outcome Measures: Improved localization of a parathyroid adenoma;   Facilitation of detection of the parathyroid adenoma at surgery
11 Not yet recruiting MBI and Breast Tomosynthesis Screening Accuracies in Patients With Dense Breast Tissue
Condition: Breast Neoplasms
Interventions: Device: MBI Scan: The LumaGEM®;   Device: 3D Mammogram/Breast Tomosynthesis Scan: Selenia® Dimensions®
Outcome Measures: Sensitivity/Cancer detection;   Specificity

These studies may lead to new treatments and are adding insight into Cardio etiology and treatment.

A major focus of Cardio research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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