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Cefuroxime Medical Research Studies

Up-to-date List of Cefuroxime Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Cefuroxime Medical Research Studies

Rank Status Study
1 Recruiting Pharmacokinetics of Small Spectrum Beta-lactam Antibiotics (Amoxicillin/Clavulanic Acid and Cefuroxime) in Patients on Intensive Care Units
Condition: Infection
Intervention:
Outcome Measures: Area under the serum concentration versus time curve (AUC) of Amoxicillin/Clavulanic acid.;   Area under the serum concentration versus time curve (AUC) of Cefuroxime.;   Severity of disease classification.;   Rate of organ failure.;   Concentration serum creatinin;   24 hour urine creatinine clearance;   Change in fluid balance;   Concentration serum albumin
2 Recruiting Antibiotics and Gut Microbiota Among Newborn Infants
Conditions: Surgical Wound Infection;   Infection; Cesarean Section;   Complications; Cesarean Section
Intervention: Drug: Cefuroxime
Outcome Measures: Maternal: incidence of post-CS infection (endometritis, urinary tract infections and wound infection) in each study group;   Infant: fecal microbiota at the tenth day of life;   Maternal: Length of hospitalization;   Maternal: readmissions to hospital on suspicion of postpartum infection following cesarean section;   Antibiotic treatment;   Infant: concentration of Cefuroxime in blood samples;   Infant: immunological analyses in blood samples on day 3
3 Not yet recruiting Randomized Controlled Trial of Postoperative Infections Following Caesarean Section Infections Following Caesarean Section
Condition: Postoperative Infection
Intervention: Drug: Cefuroxime
Outcome Measures: Women: The incidence of post-CS infection (endometritis, urinary tract infections, and wound infections);   Infant: admission to special care unit;   Women: length of the primary and any secondary hospitalization;   Women: readmissions to hospital/contact to the general practitioner on suspicion of infection after Caesarean Section;   Women: antibiotic treatment on suspicion of infection after Caesarean Section;   Infant: use of antifungal treatment against oral thrush;   Infant: necrotizing enterocolitis;   Infant: antibiotic treatment during hospital stay;   Infant: the need for intensive care treatment and length of stay in hospital;   Infant: Neonatal sepsis;   Women: Number of Participants with Adverse Events as a Measure of Safety and Tolerability
4 Unknown  Antibiotic Prophylaxis in Total Knee Prosthesis
Condition: Infection
Interventions: Drug: Cefuroxime;   Drug: placebo
Outcome Measure: infection rate
5 Unknown  Tailored Antibiotics Prophylaxis for Percutaneous Endoscopic Gastrostomy
Conditions: The Patients Who Receive Percutaneous Endoscopic Gastrostomy;   Peristomal Wound Infection After the Operation of PEG;   Prophylactic Antibiotics Before PEG
Interventions: Drug: Cefuroxime;   Drug: Tailored antibiotic
Outcome Measure: Peristomal wound infection
6 Recruiting Randomized Controlled Trial to Evaluate the Optimal Timing of Surgical Antimicrobial Prophylaxis
Condition: Surgical Site Infection
Interventions: Procedure: Early administration of SAP (Cefuroxime (plus metronidazole in colorectal surgery)) in anesthetic room (75 to 30 minutes prior to skin incision);   Procedure: Late administration of SAP (Cefuroxime (plus metronidazole in colorectal surgery)) in the operating theatre (within 30 minutes prior to skin incision)
Outcome Measures: Surgical Site Infection (SSI);   All-cause 30 day mortality;   Length of hospital stay;   Economic burden of SSI;   Nosocomial infections;   In-hospital complications
7 Unknown  Efficacy of Local Powder Prophylactics
Condition: Infection
Interventions: Biological: Vancomycin;   Biological: Vancomycin and Gentamycin;   Biological: Cefuroxime
Outcome Measure: Infection percent after surgery
8 Recruiting Antibiotic Prophylaxis for Transrectal Prostate Biopsy
Condition: Infection
Interventions: Drug: Ciprofloxacin;   Drug: trimethoprim-sulfamethoxazole;   Drug: Cefuroxime;   Drug: ceftriaxone;   Drug: gentamicin;   Drug: amikacin;   Drug: aztreonam;   Drug: imipenem
Outcome Measures: Infection rates;   Infection rate;   Demographics and medical co-morbidities;   Genus and species of rectal swab isolates with their antibiotic susceptibility profiles
9 Unknown  Examination of the Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections
Condition: Pregnancy Complications
Interventions: Drug: Preventive antibiotic treatment- NITROFURANTOIN;   Drug: Preventive antibiotic treatment- CEPHALEXIN;   Drug: PREVENTIVE TREATMENT- AMOXICILLIN;   Drug: PREVENTIVE TREATMENT- AMOXICILLIN AND CLAVULANATE POTASSIUM;   Drug: PREVENTIVE TREATMENT- Cefuroxime;   Drug: PREVENTIVE TREATMENT SULFAMETHOXAZOLE AND TRIMETHOPRIM
Outcome Measure: Urinary tract complications
10 Not yet recruiting Patients Response to Early Switch To Oral:Osteomyelitis Study
Condition: Osteomyelitis
Interventions: Drug: oral antibiotics;   Procedure: intravenous antibiotics
Outcome Measures: Clinical Failures;   Evaluation of adverse events related to the use of antibiotics;   Cost of care from the hospital perspective
11 Unknown  Prophylactic Antibiotic Treatment During Vaginal Repair
Conditions: Uterine Prolapse;   Cystocele;   Rectocele;   Enterocele
Intervention: Drug: Cefuroxime
Outcome Measure: primary endpoint: no infections (urinary tract infections, pneumonia,wound infections, infected haematomas, etc.) within 30 days postoperatively
12 Recruiting Laparoscopic Management of Periappendicular Abscess
Conditions: Appendicitis;   Abdominal Abscess
Interventions: Procedure: Laparoscopic appendectomy;   Procedure: Conservative management with percutaneous drainage
Outcome Measures: Time of hospitalization within the first 60 days after randomization;   Need of additional interventions;   Residual abscess;   Attempted procedure not successfully performed;   The number of complications;   Number recurrent abscesses
13 Unknown  The Optimization of Mycoplasm Pneumonia Antibiotic Therapy
Condition: Mycoplasma Pneumonia
Interventions: Drug: Moxifloxacin;   Drug: Cephalosporins and azithromycin
Outcome Measures: Time to resolution of fever (defined as the period from start of study-drug to relief of fever);   Time to resolution of fever (defined as the period from onset to relief of fever);   Time to resolution of respiratory symptoms(defined as the period from start of study-drug to relief of symptoms);   Time to resolution of respiratory symptoms(defined as the period from onset to relief of symptoms);   Proportion of antibiotics change;   Duration of antibiotics;   Proportion of resolution of fever after antibiotics therapy for 24 hours;   Proportion of resolution of fever after antibiotics therapy for 72 hours;   Antibiotic-related adverse reaction
14 Recruiting Cytokines and Chemokines in Erythema Migrans
Condition: Erythema Migrans
Intervention: Drug: antibiotic treatment
Outcome Measures: inflammatory proteins in erythema migrans patients;   gene polymorphisms in erythema migrans patients

These studies may lead to new treatments and are adding insight into Cefuroxime etiology and treatment.

A major focus of Cefuroxime research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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