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Cephalexin Medical Research Studies

Up-to-date List of Cephalexin Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Cephalexin Medical Research Studies

Rank Status Study
1 Recruiting A Study of Cephalexin Capsules in Healthy Participants
Condition: Healthy Volunteers
Intervention: Drug: Cephalexin
Outcome Measures: Pharmacokinetics: Area Under the Concentration Versus Time Curve of Cephalexin From Time Zero to Infinity [AUC(0-∞)] of Cephalexin Following a Single Dose;   Pharmacokinetics: Maximum Concentration (Cmax) of Cephalexin;   Pharmacokinetics: Time to Reach Maximum Observed Concentration (Tmax) of Cephalexin Following a Single Dose Maximum
2 Recruiting A Study of Cephalexin in Healthy Participants
Condition: Healthy Volunteers
Intervention: Drug: Cephalexin
Outcome Measures: Pharmacokinetics: Area Under the Concentration Versus Time Curve From Time Zero to Infinity [AUC(0-∞)] of Cephalexin Following a Single Dose;   Pharmacokinetics: Time to Reach Maximum Observed Concentration (Tmax) of Cephalexin Following a Single Dose Maximum;   Pharmacokinetics: Maximum Concentration (Cmax) of Cephalexin
3 Recruiting A Study of Cephalexin Suspension in Healthy Participants
Condition: Healthy Volunteers
Intervention: Drug: Cephalexin
Outcome Measures: Pharmacokinetics: Area Under the Concentration Versus Time Curve From Time Zero to Infinity [AUC(0-∞)] of Cephalexin Following a Single Dose;   Pharmacokinetics: Maximum Concentration (Cmax) of Cephalexin;   Pharmacokinetics: Time to Reach Maximum Observed Concentration (Tmax) of Cephalexin Following a Single Dose Maximum
4 Not yet recruiting A Study of Cephalexin Liquid for Pediatrics in Healthy Adults Participants
Condition: Healthy Volunteers
Intervention: Drug: Cephalexin
Outcome Measures: Pharmacokinetics: Area Under the Concentration Versus Time Curve From Time Zero to Infinity [AUC(0-∞)] of Cephalexin Following a Single Dose;   Pharmacokinetics: Time to Reach Maximum Observed Concentration (Tmax) of Cephalexin Following a Single Dose Maximum;   Pharmacokinetics: Maximum Concentration (Cmax) of Cephalexin
5 Recruiting Comparison of Intravenous Cefazolin Plus Oral Probenecid With Oral Cephalexin for the Treatment of Cellulitis
Condition: Cellulitis
Interventions: Drug: IV cefazolin plus oral probenecid and placebo Cephalexin;   Drug: Oral Cephalexin and saline IV plus probenecid placebo
Outcome Measure: The proportion of patients failing therapy after 72 hours of antibiotic treatment with oral Cephalexin or intravenous cefazolin plus oral probenecid.
6 Recruiting The SCOUT Study: Short Course Therapy for Urinary Tract Infections in Children
Condition: Urinary Tract Infections
Interventions: Drug: Trimethoprim sulfamethoxazole, amoxicillin-clavulanate, cefixime, or Cephalexin;   Drug: Placebo
Outcome Measures: Occurrence of treatment failures between short-course and standard-course therapies;   Occurrence of recurrent infections;   Occurrence of colonization with antimicrobial resistant bacteria;   Occurrence of asymptomatic bacteriuria;   Occurrence of clinical symptoms;   Occurrence of positive urine cultures
7 Not yet recruiting Orthognathic Surgery and Postoperative Antibiotic Use
Condition: Dentofacial Deformity
Intervention: Drug: Cefazolin, Cephalexin, Clindamycin
Outcome Measures: Rate of infection;   Side effect from antibiotic use
8 Unknown  Prophylactic Use of Antibiotics for Through and Through Lacerations of the Lip
Condition: Through-and-through Lip Lacerations
Interventions: Drug: keflex;   Drug: placebo
Outcome Measures: infection;   scar formation
9 Recruiting Antibiotic Prophylaxis for Clean Intermittent Catheterisation
Condition: Urinary Tract Infection: [Site Not Specified] or [Recurrent]
Interventions: Drug: Nitrofurantoin or Trimethoprim or Cefalexin;   Other: No prophylaxis
Outcome Measure: Relative incidence of symptomatic antibiotic‐treated UTI
10 Recruiting The Role of Antibiotics in Full Thickness Skin Graft Survival for Facial Reconstructive Surgery
Condition: Facial Defect
Intervention: Drug: Cephalexin
Outcome Measures: Graft failure rate;   Percentage surface area of graft failure
11 Not yet recruiting Antibiotic Prophylaxis in Prosthetic Breast Reconstructions
Condition: Surgical Site Infections
Interventions: Drug: Prolonged antibiotic treatment;   Drug: Short antibiotic course (standard of care)
Outcome Measure: surgical site infection
12 Unknown  Examination of the Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections
Condition: Pregnancy Complications
Interventions: Drug: Preventive antibiotic treatment- NITROFURANTOIN;   Drug: Preventive antibiotic treatment- Cephalexin;   Drug: PREVENTIVE TREATMENT- AMOXICILLIN;   Drug: PREVENTIVE TREATMENT- AMOXICILLIN AND CLAVULANATE POTASSIUM;   Drug: PREVENTIVE TREATMENT- CEFUROXIME;   Drug: PREVENTIVE TREATMENT SULFAMETHOXAZOLE AND TRIMETHOPRIM
Outcome Measure: Urinary tract complications
13 Recruiting Prevention of Arrhythmia Device Infection Trial (PADIT)
Condition: Arrhythmia
Interventions: Drug: Incremental;   Drug: Conventional
Outcome Measures: Hospitalization attributed to device infection;   1. Proven device infection not requiring surgical intervention (medically treated device infection).;   2. Any treatment with antibiotics for suspected device infection.;   3. Antibiotic-related adverse events including culture or antigen proven C. difficile infection.;   4. Prolongation of hospitalization due to proven or suspected adverse events from the antibiotic therapy.;   Cost benefit analysis;   6. Rate of device/lead extraction 12 months post patient's procedure (regardless of the cause).
14 Unknown  Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use
Conditions: Snoring;   Strep Throat
Interventions: Other: No postoperative antibiotic;   Drug: Amoxicillin;   Drug: Amoxicillin/clavulanate potassium;   Drug: Azithromycin;   Drug: Cefaclor;   Drug: Cephalexin;   Drug: Cefdinir;   Drug: Clindamycin
Outcome Measure: Healthcare Utilization
15 Recruiting Effects of Treatments on Atopic Dermatitis
Conditions: Dermatitis, Atopic;   Human Volunteers;   Eczema;   Atopic Dermatitis
Interventions: Drug: Trimethoprim/sulfamethoxazole;   Drug: Cephalexin;   Drug: Doxycycline;   Other: Sodium hypochlorite (bleach)
Outcome Measures: To characterize microbiome alterations in healthy adult volunteers (Cohorts 1 and 2) and pediatric patients with AD and associated active bacterial infection (Cohort 3) after treatment.;   To obtain samples from healthy adult volunteers to evaluate and refine genomic analysis of human microbes. To examine how different treatments may alter the human microbiome.
16 Not yet recruiting Antibiotics and Tissue Expanders in Breast Reconstruction
Condition: Complications; Breast Prosthesis, Infection or Inflammation
Intervention: Drug: antibiotic
Outcome Measures: Surgical site infection;   Surgical site infection requiring implant/expander removal
17 Unknown  Moxifloxacin Versus Ceftriaxone in the Treatment of Primary Pyogenic Liver Abscess
Condition: Liver Abscess
Interventions: Drug: Moxifloxacin (Avelox);   Drug: ceftriaxone (Rocephin/Cefin)
Outcome Measures: Treatment efficacy;   Clinical response;   Clinical and radiological response;   All cause mortality;   Mortality attributable to liver abscess during treatment;   Rates of complication (metastatic infections to the central nervous system and/or eyes);   Rates of gastrointestinal colonization of Klebsiella pneumoniae in patients and rates of resistance post-antibiotic use.
18 Not yet recruiting Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon
Conditions: Hand Laceration;   Tendon Involved;   Clean Laceration;   No Bone Involved
Intervention: Drug: Antibiotic-Cefamezin
Outcome Measure: rate of wound infections

These studies may lead to new treatments and are adding insight into Cephalexin etiology and treatment.

A major focus of Cephalexin research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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