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Cerebral Infarction Medical Research Studies

Up-to-date List of Cerebral Infarction Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Cerebral Infarction Medical Research Studies

Rank Status Study
1 Recruiting Post-Stroke Disease Management - Stroke Card
Conditions: Stroke;   Ischemic Attack, Transient;   Secondary Prevention;   Disease Management;   Cost-Benefit Analysis
Interventions: Behavioral: Active Comparator: Extended Standard Care (Stroke Card);   Behavioral: Active Comparator: Standard Care
Outcome Measures: Major recurrent (post-discharge) cardiovascular events [nonfatal stroke, nonfatal myocardial infarction, and vascular death];   Health-related QoL (European Quality of Life-5 Dimensions EQ-5D-3L - overall health utility score);   Recurrent stroke (both ischemic and hemorrhagic) and TIA;   Death from all causes;   Functional outcome;   Quality-of-Life 5 individual dimensions (mobility, self-care, usual activities, pain and discomfort, anxiety and depression);   Target level achievement in secondary prevention;   Cost-effectiveness;   Number of out-of-schedule consultations of physicians and out-patient hospital services, and out-of-schedule hospital admissions
2 Recruiting Community Engagement for Early Recognition and Immediate Action in Stroke
Condition: Ischemic Stroke
Intervention: Behavioral: Community-based Stroke Awareness Program
Outcome Measures: Early arrival after stroke onset;   Emergency medical services (EMS) utilization for stroke;   Knowledge, self-efficacy, and perceptions
3 Recruiting Determining Optimal Post-Stroke Exercise (DOSE)
Conditions: Cerebrovascular Accident;   Stroke;   Cerebral Infarction;   Brain Infarction;   Brain Ischemia;   Cerebrovascular Disorders;   Brain Diseases;   Central Nervous System Diseases;   Nervous System Diseases;   Vascular Diseases
Interventions: Behavioral: Stroke Management Program (SMP);   Behavioral: Stroke Monitoring Program (SMonP);   Behavioral: Stroke Supplementary Program (SSP)
Outcome Measures: Ambulatory function measured by the Six Minute Walk Test;   Ambulatory Function from the Six Minute Walk Test;   Ambulatory function from the 5 Meter Walk Test;   Balance function from the Berg Balance Scale;   Ambulatory function from the Functional Ambulation Classification;   Functional level measured by the Functional Independence Measure;   Quality of life measured with EuroQol;   Cognition measured by the Montreal Cognitive Assessment;   Cognition measured by the Digit Symbols Substitution Test;   Cognition measured by the Trail Making Test;   Depression measured by Patient Health Questionnaire-9
4 Not yet recruiting Stepping up Aerobic Exercise to Improve Health Outcomes After Stroke
Condition: Stroke
Intervention: Behavioral: Aerobic Exercise Screening and Prescription Clinic
Outcome Measures: Change from admission 6-Minute Walk Test at discharge;   Change from admission 10-Meter Walk at discharge;   Change from admission resting blood pressure at discharge;   Change from admission abdominal girth at discharge;   Change from admission Stroke-Specific Quality of Life at discharge;   Change from admission Readiness for Physical Activity Scale at discharge;   Change from admission Fatigue Severity Scale at discharge
5 Recruiting A Self-efficacy Enhancing Stroke Self-management Program for Community-dwelling Stroke Survivors
Condition: Stroke
Interventions: Behavioral: Stroke self-management program;   Behavioral: Usual care
Outcome Measures: Self-efficacy in performing stroke self-management behaviors;   Stroke self-management behaviors;   Health-related quality of life;   Depressive symptoms;   Community reintegration;   Outcome expectation
6 Unknown  Non-invasive Brain Stimulation and Occupational Therapy To Enhance Stroke Recovery
Conditions: Stroke;   Cerebrovascular Accident;   CVA;   Acute Stroke;   Acute Cerebrovascular Accident;   Apoplexy
Interventions: Device: Transcranial Direct Current  Stimulation;   Device: Transcranial Direct Current Stimulation
Outcome Measures: 3-Joint Range of  Motion (3J-ROM);   Fugl-Meyer Assessment of Upper Extremity Motor Impairment;   Wolf-Motor-Function-Test;   Functional MRI Activation Pattern;   Diffusion Tensor Imaging;   Transcranial Magnetic Stimulation (TMS);   Motor Activity Log Rating Scales;   Modified Ashworth Scale
7 Recruiting Nimodipine for Treating Acute Massive CEREBRAL INFARCTION
Condition: Cerebral Infarction
Interventions: Drug: Nimodipine;   Drug: Saline + citicoline
Outcome Measure: Neurological deficits after stroke will be assessed using the National Institute of Health Stroke Scale scores
8 Recruiting RELAXED: Recurrent Embolism Lessened by Rivaroxaban for Acute Ischemic Stroke
Conditions: Stroke, Acute;   Atrial Fibrillation
Intervention: Other: This is an observational study
Outcome Measures: Recurrent ischemic stroke and major bleeding;   ischemic stroke and transient ischemic attack;   Composite cardiovascular events;   Any bleeding events;   Intracranial hemorrhage;   Hemorrhagic transformation of cerebral infarcts;   Adverse event;   Recurrence of ischemic stroke and major bleeding according to whether or not heparin is administered;   Recurrence of ischemic stroke and major bleeding according to whether rivaroxaban is administered in the morning or evening;   Duration of hospitalization;   Safety and efficacy of rivaroxaban administration via tube or by crush tablet;   Definite clinical data on patients developing recurrent ischemic stroke or intracranial hemorrhage during rivaroxaban medication;   Medical expenditures using a model
9 Recruiting Center for Stroke Research Berlin (CSB) Prospective Stroke Cohort
Condition: Stroke
Intervention:
Outcome Measures: Combined vascular endpoint composed of stroke, myocardial infarction, and vascular death;   Course of cognitive function;   Course of depression
10 Unknown  Electroencephalograph for Detection of Acute Ischemic Stroke
Condition: Stroke
Intervention: Device: Neurokeeper stroke detector
Outcome Measures: Detection of stroke;   Correlation to severity of stroke
11 Unknown  Validation of an Electroencephalograph Based Algorithm for Detection of Onset and Deterioration of Acute Ischemic Stroke by Comparison to NIHSS
Condition: Stroke
Intervention: Device: Neurokeeper stroke detector
Outcome Measures: Detection of stroke;   Correlation to severity of stroke
12 Unknown  Surgical Manipulation of the Aorta and CEREBRAL INFARCTION
Conditions: Coronary Heart Disease;   Stroke;   Cerebral Infarction
Interventions: Procedure: OBCAB (Off Pump Coronary Artery Bypass Grafting);   Procedure: CABG (coronary artery bypass grafting)
Outcome Measures: occurrence and number of CEREBRAL INFARCTIONs assessed by magnetic resonance imaging;   mortality;   stroke;   delirium;   neurocognitive performance;   multi-organ failure;   myocardial infarction;   completeness of revascularisation
13 Recruiting Healthy Lifestyles After Stroke
Conditions: Stroke;   Apoplexy;   Cerebral Stroke;   Cerebrovascular Accident;   Cerebrovascular Accident, Acute;   Cerebrovascular Apoplexy;   Cerebrovascular Stroke;   CVA;   Stroke, Acute;   Vascular Accident, Brain
Intervention: Behavioral: Healthy Lifestyle Training Program
Outcome Measures: Changes from baseline in global measure of lifestyle behavior (Health Promoting Lifestyle Profile II) at 6 months and 12 months.;   Daily walking physical activity;   Dietary behavior (26 items SmartDiet Questionnaire);   Medication adherence;   Depressive symptoms (20-item Centre for Epidemiological Studies-Depression [CES-D] Scale);   Cognition (Montreal Cognitive Assessment [MoCA]);   Cardiovascular risk factors (resting blood pressure, lipid, and glucose profiles);   Body composition (Body Mass Index, waist circumference);   Health-related quality of life (SF-36);   Health and Social Services Utilization (Health and Social Service Utilization Inventory)
14 Recruiting Critical Periods After Stroke Study (CPASS)
Conditions: Stroke;   Brain Infarction;   Brain Ischemia;   Cerebral Infarction;   Cerebrovascular Disorders
Interventions: Behavioral: Early Intensive upper extremity motor training;   Behavioral: Sub-acute intensive upper extremity motor training;   Behavioral: Chronic intensive upper extremity motor training
Outcome Measures: Action Research Arm Test (ARAT);   Motor Activity Log - 28 Quality of Movement (MAL-28 QOM);   Nine Hole Peg Test (9-HPT);   Functional Independence Measure (FIM);   Motor Assessment Scale - Upper Arm Function (MAS);   Barthel Index (BI);   Motricity Index - Arm only (MI);   Stroke Impact Scale - perceptions of change (SIS-POC);   Stroke Impact Scale - Hand-Arm subscale (SIS);   Modified Rankin Scale (MRS);   Activity Card Sort (ACS);   Reintegration to Normal Living Index (RNLI);   Geriatric Depression Scale (GDS-15);   NIH Stroke Scale (NIHSS);   Short Blessed Orientation and Memory Concentration Test (SBT);   Mesulam Symbol Cancellation Test (SCT);   Faces Pain Scale
15 Recruiting Stroke Self-Management
Condition: Stroke
Intervention: Behavioral: Stroke Self-Management
Outcome Measure: Change in Stroke, Specific Quality of Life
16 Recruiting SlagSens (Effect of Tactile Stimulation After Stroke)
Condition: Stroke
Intervention: Other: Specific treatment in addition to standard stroke care
Outcome Measures: Weinstein Enhanced sensory test (WEST);   Disk-Criminator;   NIH Stroke Scale (NIHSS)
17 Recruiting Exercise For Sub-acute Stroke Patients in Jamaica
Condition: Stroke
Interventions: Procedure: Task Oriented Exercise Training;   Procedure: Stroke Care "Get with the Guidelines"
Outcome Measures: Thigh and Abdominal muscle and fat;   Whole body protein and skeletal muscle synthesis and breakdown;   Muscle myosin heavy chain isoform (MHC) proportions;   Leg Strength;   Fitness;   Glucose tolerance;   Muscle TNF alpha;   Mobility and balance
18 Recruiting Immunological Biomarkers in Patients With Acute Ischemic Stroke
Condition: Ischemic Stroke
Intervention:
Outcome Measures: Predictive immune score for favorable outcome;   Predictive immune score for stroke associated infection;   Predictive immune score for ischemic progression;   Predictive immune score for functional outcome over the entire mRS;   Localization and stroke volume analysis;   Insular cortex involvement and infarct volume;   Infection and functional outcome after ischemic stroke;   Thrombolysis, immune biomarkers and SAI
19 Not yet recruiting Identification of Hypoxic Brain Tissues by F-MISO PET in Acute Ischemic Stroke
Condition: Ischemic Stroke
Intervention: Other: PET and MRI
Outcome Measures: volume and location of F-MISO uptake in stroke patients;   comparison of F-MISO uptake areas and ischemic lesions defined by weighted diffusion and FLAIR on
20 Not yet recruiting Brazilian Intervention to Increase Evidence Usage in Practice - Stroke ( BRIDGE-Stroke)
Condition: Acute Ischemic Stroke
Intervention: Behavioral: Multifaceted Strategy
Outcome Measures: Frequency of Evidence Based Strategies;   "All or None" Quality Measures;   Discharge Prescription;   Total Mortality;   Stroke Recurrence;   Disability

These studies may lead to new treatments and are adding insight into Cerebral Infarction etiology and treatment.

A major focus of Cerebral Infarction research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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