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Cetrotide Medical Research Studies

Up-to-date List of Cetrotide Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Cetrotide Medical Research Studies

Rank Status Study
1 Unknown  Study on Influence of Leutinizing Hormone (LH) on Oocyte Maturity
Condition: Infertility
Interventions: Drug: Cetrorelix;   Drug: Luprolide Acetate
Outcome Measures: Number of mature oocytes immediately after oocyte recovery;   Clinical pregnancy
2 Recruiting Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
Conditions: Menopause;   Aging;   Vascular Health
Interventions: Drug: KUVAN;   Drug: Placebo;   Drug: Cetrotide;   Drug: Climara;   Drug: Placebo transdermal patch
Outcome Measures: Change in brachial artery flow-mediated dilation;   Change in carotid artery compliance and endothelial cell protein expression
3 Recruiting Use of Degarelix in Controlled Ovarian Hyperstimulation (COH) Protocol for Women With PoliCystic Ovarian Syndrome (PCOS)
Conditions: PCOS;   OHSS;   INFERTILITY
Interventions: Drug: degarelix (long acting GnRH antagonist);   Drug: cetrorelix 0.25mg
Outcome Measures: PREGNANCY RATE;   ovarian hyperstimulation syndrome rate;   implantation rate
4 Unknown  Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression
Conditions: Female Infertility Due to Nonimplantation of Ovum;   Complications Associated With Artificial Fertilization
Interventions: Drug: Pergoveris in long protocol with GnRH agonist;   Drug: Pergoveris in GnRH antagonist protocol
Outcome Measures: number of mature oocytes;   incidence of ovarian hyperstimulation syndrome (OHSS);   The number of early miscarriages.;   The number of participants with adverse events.
5 Recruiting GnRH Antagonist Versus GnRH Agonist in Polycystic Ovary Syndrome During in Vitro Fertilization - Embryo Transfer
Conditions: Infertility;   Polycystic Ovary Syndrome
Interventions: Drug: GnRH antagonist (Cetrorelix);   Drug: Conventional GnRH agonist (Triptorelin)
Outcome Measures: number of oocyte retrieved;   pregnancy rate
6 Not yet recruiting The Comparison of Effect of Four Different Treatment Protocols on IVF Outcomes in Poor Responders Undergoing in Vitro Fertilization.
Condition: Poor Responders Undergoing IVF
Interventions: Drug: GnrH Antagonist/letrozole protocol (Cetrotide; serono + Femara; Novartis Pharma AG);   Drug: microdose flare-up protocol (Lucrin; Abbott + Gonal F, Serono);   Drug: Antagonist/clomiphene protocol (Cetrotide; serono + Klomen, Kocak pharma);   Drug: GnRH antagonist protocol (Cetrotide, Serono)
Outcome Measures: clinical pregnancy rates;   total number of oocytes retrieved
7 Not yet recruiting The Results of Preimplantation Genetic Diagnosis and Preimplantation Genetic Screening of Embryos Obtained From GnRH-agonist Long and GnRH-antagonist Ovarian Stimulation Protocol
Condition: Embryo's Genetic and Chromosomal Quality
Interventions: Drug: ghrh antagonist (Cetrotide/orgalutran);   Drug: gnrh agonist (suprefact)
Outcome Measure: The results of Preimplantation Genetic Diagnosis and Preimplantation Genetic Screening of embryos obtained from GnRH-agonist long and GnRH-antagonist ovarian stimulation protocol
8 Unknown  Growth Hormone for Poor Responders in in Vitro Fertilization (IVF)
Condition: In Vitro Fertilization
Interventions: Drug: Growth Hormone;   Drug: Patch protocol
Outcome Measures: number of mature oocytes retrieved;   duration of stimulation;   gonadotropin requirements;   number of cumulus-oocyte complexes retrieved;   number of fertilized oocytes;   proportion of patients reaching embryo transfer;   implantation rate;   clinical pregnancy rate
9 Recruiting Endometrial Injury and IVF Outcome Parameters in Patients With Failed IVF Cycles
Condition: Infertility/ Failed IVF Cycles
Interventions: Procedure: Endometrial injury by hysteroscopy or pipelle sampling;   Procedure: Proceed to COH directly
Outcome Measures: Live Birth Rate;   Clinical Pregnancy Rate;   Implantation rate;   Biochemical pregnancy rate;   Ectopic pregnancy rate;   Miscarriage rate;   Ongoing pregnancy rate;   Pregnancy complications (preterm birth, placental abnormalities, bleeding throughout pregnancy, pregnancy related hypertensive disorders, IUGR and SGA)
10 Recruiting Addition of Prednisolone and Heparin in Patients Undergoing Controlled Ovarian Hyperstimulation (COH) for In Vitro Fertilization (IVF) With Failed IVF Cycles
Condition: Infertility
Interventions: Drug: Prednisolone and Heparin during COH for IVF;   Drug: COH for IVF
Outcome Measures: live birth rate;   clinical pregnancy rate
11 Recruiting IVF/ICSI Protocols in Poor Responders With Growth Hormone
Condition: Female Infertility Due to Diminished Ovarian Reserve
Intervention: Drug: Growth hormone (Norditropin, Novo nordisk)
Outcome Measure: Numbers of oocytes retrieved and number of fertilized oocytes
12 Not yet recruiting Comparison of Ovarian Mild Stimulation and Controlled Ovarian Stimulation in Poor Ovarian Responders
Condition: Infertility
Interventions: Other: mild stimulation protocol;   Other: controlled ovarian stimulation
Outcome Measures: clinical pregnancy rate;   live birth rate;   Number of oocytes retrieved;   Number of transferrable embryo;   normal fertilization rate;   implantation rate;   ongoing pregnancy rate;   Total dose of recombinant FSH consumption;   length of stimulation;   serum estradiol level;   serum LH level;   serum progesterone level;   serum FSH level;   FSH level in follicular fluid;   LH level in follicular fluid;   Estradiol level in the follicular fluid;   progesterone level in follicular fluid;   testerone level in the follicular fluid;   anti-müllerian hormone (AMH)level in follicular fluid;   Ovarian Hyperstimulation Syndrome (OHSS) rate
13 Recruiting Growth Hormone in Poor Responders to IVF Trial
Condition: Infertility
Interventions: Drug: Saizen (Human Growth Hormone);   Drug: No Saizen Control (Standard IVF Protocol)
Outcome Measures: Oocyte yield;   Pregnancy rate
14 Recruiting Synchronization of Ovarian Stimulation for in Vitro Fertilization With Follicular Wave Emergence
Condition: Infertility
Interventions: Drug: Ovulation induction with choriogonadotropin alfa;   Procedure: Aspiration of the dominant follicle;   Other: Control
Outcome Measures: Emergence of an ovarian follicular wave after dominant follicle aspiration or hCG administration;   Follicular growth pattern on ultrasound scan;   Estradiol and progesterone levels during ovarian stimulation;   Number of mature oocytes retrieved;   Total dose of gonadotrophins used;   Fertilization rate;   Pregnancy rate

These studies may lead to new treatments and are adding insight into Cetrotide etiology and treatment.

A major focus of Cetrotide research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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