sponsored
PatientsVille.com Logo

PatientsVille

Chest Pain Medical Research Studies

Up-to-date List of Chest Pain Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Chest Pain Medical Research Studies

Rank Status Study
1 Recruiting Shared Decision Making in the Emergency Department: CHEST PAIN Choice Trial
Conditions: Chest Pain;   Acute Coronary Syndrome
Intervention: Other: Chest Pain Choice Decision Aid
Outcome Measures: Test if CHEST PAIN Choice safely improves validated patient-centered outcome measures.;   Test if the decision aid has an effect on healthcare utilization within 30 days after enrollment.;   Test if the decision aid safely improves additional validated patient outcome measures.
2 Unknown  Coronary CT Angiography in Acute CHEST PAIN is a Cost Effective Risk Stratification Strategy
Condition: Acute Chest Pain
Intervention: Procedure: Coronary CT Angiogram
Outcome Measures: Determine if the cumulative costs over 90-days of providing treatment services are reduced when adding coronary CTA to the standard-of-care (CTA + SOC) in patients with acute CHEST PAIN compared to SOC alone.;   Determine if the rate of hospitalizations, nuclear perfusion scans and interventional cardiac catheterizations will be reduced by adding the coronary CTA to the SOC (CTA + SOC) compared to the SOC alone.;   Compare the rate of death, myocardial infarct (MI), acute coronary syndrome (ACS), and recidivism to the ED over 90-days when adding coronary CTA to the SOC (CTA + SOC) in ED patients with acute CHEST PAIN compared to the SOC alone group.
3 Recruiting Impact on Management of the HEART Risk Score in CHEST PAIN Patients
Condition: Chest Pain
Interventions: Other: usual care;   Other: use of HEART risk score
Outcome Measures: MACE;   cost-effectiveness
4 Recruiting ProspEctive First Evaluation in CHEST PAIN Trial
Conditions: Chest Pain;   Shortness of Breath;   Suspected Acute Coronary Syndrome
Interventions: Procedure: Coronary CT Angiography;   Procedure: Stress Test
Outcome Measures: Change in medication regimen.;   Change in CAD risk profile (blood pressure, lipid profile, weight, and HgbA1C;   Time to discharge from hospital;   All-cause mortality;   Cardiovascular mortality;   Non-fatal myocardial infarction
5 Recruiting Myocardial Ischemia Detection for Early Identification of Patients With Ischemic CHEST PAIN
Conditions: Cardiac Ischemia;   Chest Pain;   Shortness of Breath
Intervention: Other: 12-lead holter monitor application
Outcome Measure: Myocardial ischemia
6 Not yet recruiting Hypnotherapy in Patients With CHEST PAIN & Unobstructed Coronaries
Conditions: Chest Pain;   Unobstructed Coronary Arteries
Interventions: Behavioral: Hypnotherapy;   Behavioral: Supportive therapy
Outcome Measures: Symptom frequency;   Symptom severity;   Psychological morbidity;   Quality of life;   Hospitalisations;   Consultancy time;   Medication use
7 Unknown  A Study of the Use of Combination of Anti-cholinergic and Minor Tranquilliser in the Treatment of Non-cardiac CHEST PAIN - a Double Blind Placebo Controlled Study
Condition: Chest Pain
Intervention: Drug: chlordiazepoxide 5 mg, clidinium 2.5 mg, twice daily
Outcome Measures: Symptoms scores, quality of life;   Compliance;   Adverse effects
8 Unknown  A Study of the Use of High-dose Proton Pump Inhibitor for the Treatment of Gastro-oesophageal Reflux Related Non-cardiac CHEST PAIN - a Randomized Double-blind Placebo-controlled Study
Condition: Chest Pain
Intervention: Drug: Rabeprazole 20mg twice daily
Outcome Measures: Symptoms assessment, quality of life.;   Compliance;   Adverse effects
9 Recruiting Lung Ultrasound in Pleuritic CHEST PAIN
Conditions: Community Acquired Pneumonia;   Pleuritis;   Pulmonary Embolism;   Lung Cancer
Intervention: Procedure: Lung ultrasound
Outcome Measures: Sensitivity and specificity of lung ultrasound in pneumonia, chest wall pain, lung cancer, pulmonary embolism or other causes in patients presenting with pleuritic CHEST PAIN.;   Accuracy of ultrasound in distinguishing lung consolidation in pneumonia, atelectasis, pulmonary infarction or tumors
10 Unknown  German CHEST PAIN Unit (CPU)-Register
Condition: Chest Pain
Intervention:
Outcome Measures: Internal and external validation of the medical care quality in the field of CHEST PAIN Units, including benchmark reports and risk adjusted comparisons.;   Documentation of CPU complications including mortality, serious but not fatal complications (e.g. stroke, heavy and moderate bleedings etc) as well as documentation of medication at hospital discharge.;   Documentation of long-term mortality and serious but non-fatal complication (SCI, stroke, TIA, heavy bleeding etc.) as well as hospital admissions and medication after 3 months.
11 Recruiting Cardiac Magnetic Resonance Imaging Strategy for the Management of Patients With Acute CHEST PAIN and Detectable to Elevated Troponin
Conditions: Acute Coronary Syndrome;   Chest Pain
Interventions: Procedure: Cardiac MRI;   Other: ACC/AHA Guideline adherent care
Outcome Measures: Reduction in composite death, nonfatal myocardial infarction (MI), and cardiac related readmission;   Reduction in invasive angiography.;   Reduction in coronary revascularization.;   Reduction in recurrent cardiac testing.;   Reduction in cardiac-related ED visits.
12 Unknown  Usefulness of High-frequency QRS Analysis in the Evaluation of Patients With CHEST PAIN
Conditions: Acute Coronary Syndrome;   STEMI;   NSTEMI;   Unstable Angina;   Chest Pain
Intervention:
Outcome Measure: diagnosis or rule-out of acute coronary syndrome
13 Unknown  Trial for the Use of Pretest Probability to Reduce Unnecessary Testing for Low-Risk Patients With CHEST PAIN
Condition: Acute Coronary Syndrome
Intervention: Device: PREtest Consult
Outcome Measures: Documented myocardial infarction (ESC criteria);   Death thought to be from ACS (autopsy not required);   Need for revascularization (stent or surgical) within 45 days;   Cardiac catheterization demonstrating;   Percentage of patients deemed very low risk (pretest probability less than 2%) by the physician or the PREtest Consult ACS platform during the index visit;   Percentage of patients discharged without admission to the hospital or emergency department CHEST PAIN unit during the index visit;   Length of stay for the index visit to the emergency department;   Incidence of stress testing, cardiac imaging and cardiac catheterization during the index visit and in the 45 days following the index visit;   Hospital charges billed to each patient or their insurance provider for the index visit;   Rate of reimbursement to the hospital for the index visit of each patient;   Patient satisfaction as recorded by a survey instrument during a phone interview seven (7) days post-index visit
14 Not yet recruiting Copeptin Testing During Pre-hospital Care in the Treatment of CHEST PAIN Suggestive of Acute Coronary Syndrome
Condition: Chest Pain
Interventions: Biological: Blood work in the ambulance;   Biological: Blood work upon arrival in the emergency room;   Biological: Blood work at 3 hours post-arrival in the emergency room
Outcome Measures: Blood troponin HS concentration (µg/L);   Blood copeptin concentration (pmol/l);   Final diagnosis of ACS non ST + (yes/no);   Mortality;   Would you leave the patient at home if both copeptin and troponin tests were negative?;   Hospital costs (€) associated with avoidable services;   Distance (km) between the hospital and the patient's place of residence;   Time spent by ambulance staff at the patient's place of residence;   Presence/absence of another diagnosis;   Number of patients taken in charge that day by ambulance staff.
15 Unknown  Prognosis of Very Low Dose SPECT
Condition: Chest Pain
Intervention:
Outcome Measures: Percentage of patients free of composite endpoint;   Percentage of patients for whom rest imaging is needed.;   Image quality on a 5 point scale;   Average effective dose of radiation received by all patients.;   Average effective dose received by patients for whom stress-only MPS is performed.;   Duration of stress test;   Duration of hospitalization
16 Recruiting Are Serial Electrocardiograms Additive to SeriAl Second-generations Troponins in Predicting Acute CoronAry Syndromes in PatienTs With Undifferentiated CHEST PAIN
Conditions: Acute Coronary Syndrome;   Chest Pain
Intervention: Device: Serial Electrocardiograms
Outcome Measures: Major Adverse Cardiovascular Events at 30 days;   Evidence of acute myocardial ischemia via objective cardiac testing performed during the index hospitalization
17 Recruiting Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to CHEST PAIN Unit
Conditions: Myocardial Infarction;   Death;   Cerebrovascular Accident;   Congestive Heart Failure;   Angina Pectoris
Intervention:
Outcome Measures: The association of EndoPat and short-term and long-term outcomes;   The comparison of different imaging modalities on short- and long-term outcomes
18 Unknown  Role of Esophageal Mast Cell Activation in Noncardiac CHEST PAIN (NCCP)
Condition: Noncardiac Chest Pain (NCCP)
Intervention:
Outcome Measure:
19 Recruiting Low-Dose Coronary Computed Tomographic Angiography for Early Triage of Acute CHEST PAIN
Condition: Chest Pain
Interventions: Other: Low-dose Cardiac CT protocol;   Other: Conventional cardiac CT protocol
Outcome Measures: Proportion of patients having hard events (death, MI) after negative low-dose CCTA findings;   Direct comparison of accuracy (sensitivity, specificity, PPV, NPV) for between low-dose and conventional cardiac CT;   Direct comparison of frequency and overall cost of additional tests such as echocardiography, treadmill test, myocardial SPECT and coronary angiography;   Total radiation dose exposed by index CT imaging and additional tests including SPECT and invasive angiography;   Total length of ED and hospital stay
20 Recruiting HEART Pathway Implementation
Conditions: Chest Pain;   Acute Coronary Syndrome;   Chest Pain Atypical Syndrome;   Chest Pain Rule Out Myocardial Infarction
Intervention:
Outcome Measure: Hospitalization rate

These studies may lead to new treatments and are adding insight into Chest Pain etiology and treatment.

A major focus of Chest Pain research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


Discuss Chest Pain