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Chorionic Medical Research Studies

Up-to-date List of Chorionic Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Chorionic Medical Research Studies

Rank Status Study
1 Recruiting A Study of Human Chorionic Gonadotrophin as Luteal Phase Support in Frozen Embryo Transfer
Condition: Subfertility
Interventions: Drug: Human Chorionic gonadotrophin;   Drug: Placebo
Outcome Measures: ongoing pregnancy rate;   Rate of pregnancy loss per number of transfer cycles
2 Recruiting Effect of hCG on Receptivity of the Human Endometrium
Conditions: Infertility;   Subfertility
Interventions: Drug: human Chorionic gonadotropin (hCG);   Drug: Placebo Comparator (for hCG)
Outcome Measures: Evaluate the effect of hCG on endometrial gene and protein expression levels;   Evaluate the effect of hCG on endometrial secretory proteins.
3 Unknown  Detection of Human Chorionic Gonadotropin by Interferometry in Gestational Trophoblastic Disease
Condition: Trophoblastic Neoplasms
Interventions: Drug: chemotherapy agents;   Procedure: suction curettage
Outcome Measure:
4 Unknown  Evaluation of the Luteolytic Effect of a Gonadotropin Releasing Hormone (GnRH) Agonist After the Administration of Human Chorionic Gonadotropin (hCG) in the Initial Follicular Phase a Its Influence on the Prognosis of in Vitro Fertilization Treatment
Condition: Infertility
Interventions: Drug: GnRH agonist;   Drug: Control
Outcome Measures: Frequency of functional rescue of corpus luteum;   Pregnancy rate;   Levels of serum steroids;   Levels of serum gonadotropins
5 Recruiting The Effects of Two Endometrium Preparation Protocols in Frozen-thawed Embryo Transfer in Women With Irregular Cycles
Condition: Infertility
Interventions: Drug: Letrozole and human Chorionic gonadotrophin;   Drug: estradiol and progesterone
Outcome Measures: ongoing pregnancy rate;   pregnancy rate;   clinical pregnancy rate
6 Unknown  Conformation of Beta Human Chorionic Gonadotropin During Chemotherapy for Choriocarcinoma
Conditions: Trophoblastic Neoplasms;   Choriocarcinoma
Interventions: Device: atomic force microscopy;   Device: dual polarisation interferometry
Outcome Measure:
7 Unknown  Human Chorionic Gonadotropin Supplementation Prior to In-vitro Fertilization Treatment in Poor Responders
Condition: Infertility
Intervention: Drug: Ovitrelle
Outcome Measure: number of oocytes retrieved
8 Recruiting Dual Trigger to Reduce Ovarian Hyperstimulation Syndrome
Condition: Infertility and at High Risk of OHSS
Interventions: Drug: triptorelin;   Drug: hCG
Outcome Measures: clinical pregnancy rate per transfer cycle;   numbers of patients having OHSS;   oocyte yield;   Oocyte maturity;   serum luteinizing hormone level 12 hours post trigger;   serum hCG level 12 hours post trigger;   fertilization rate;   implantation rate
9 Recruiting Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS)
Condition: PCOS
Interventions: Drug: Dexamethasone;   Drug: recombinant human Chorionic gonadotropin (r-hCG)
Outcome Measures: 17OHP;   Testosterone;   Androstenedione;   DHEA
10 Unknown  Safety Study of Human Chorionic Gonadotropin (hCG) and Epoetin Alfa (EPO) in Traumatic Brain Injury: Dosing Tier 1
Condition: Traumatic Brain Injury
Intervention: Drug: NTx 265
Outcome Measures: Safety;   Efficacy
11 Recruiting Human Chorionic Gonadotrophin in an Antagonist Protocol
Condition: Infertility
Interventions: Drug: Low dose HCG;   Drug: Placebo
Outcome Measures: Number of oocytes;   Pregnancy rate;   Cost of antagonist treatment;   Spiral artery Doppler indices;   The percentage of the perifollicular vascularity using power doppler
12 Recruiting Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome
Condition: Polycystic Ovary Syndrome
Interventions: Radiation: 3-D Ultrasound;   Drug: recombinant human Chorionic gonadotropin;   Drug: Recombinant follicle stimulating hormone;   Drug: Dexamethasone;   Drug: Adrenocorticotropin;   Drug: Glucose
Outcome Measures: 17-hydroxyprogesterone responses to hCG with and without FSH in PCOS women and normal controls;   Follicle count on 3-D Ultrasound in PCOS women and normal controls;   Adrenal androgen response to ACTH in PCOS women and normal controls;   17-hydroxyprogesterone response to hCG in the setting of reduced insulin secretion in PCOS women
13 Unknown  Effect of Short Term Ovarian Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess
Conditions: Hyperandrogenemia;   Obesity;   Polycystic Ovary Syndrome
Interventions: Drug: Leuprolide;   Drug: Dexamethasone;   Drug: recombinant human Chorionic gonadotropin
Outcome Measures: 17 hydroxyprogesterone responses to rhCG before and 4 weeks after depot leuprolide administration;   Ovarian hormone precursor responses to rhCG before and 4 weeks after depot leuprolide administration
14 Not yet recruiting Dehydrated Human Amnion/Chorion Membrane (dHACM) for Recovery After Fractionated Ablative CO2 Laser Resurfacing of the Face
Condition: Scarring
Interventions: Other: Application of Sterile 0.9% Saline Solution;   Other: Application of dHACM
Outcome Measures: The time to healing for both groups will be assessed as defined by appearance and 100% epithelialization.;   Erythema, edema, crusting, and exudate will be compared between both groups.
15 Recruiting Natural Cycle In Vitro Fertilization
Condition: Natural Cycle in Vitro Fertilization (IVF)
Interventions: Procedure: Uterine Aspiration and Endometrial Biopsy/Embryo Biopsy;   Drug: Leuprolide Acetate;   Drug: Human Chorionic Gonadotropin (hCG)
Outcome Measures: Endometrial Changes;   Aneuploidy Rates
16 Recruiting Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART)
Condition: Infertility
Interventions: Drug: Pergoveris®;   Drug: GONAL-f®;   Drug: Recombinant human Chorionic gonadotrophin (r-hCG)
Outcome Measures: Total number of retrieved oocytes;   Ongoing pregnancy rate;   Live birth rate;   Embryo implantation rate;   Clinical pregnancy rate;   Biochemical pregnancy rate
17 Not yet recruiting ITT-5 Mechanisms of Spermatogenesis
Condition: Gonadotropin Deficiency
Interventions: Drug: Testosterone 1% Gel;   Drug: Acyline;   Drug: Dutasteride;   Drug: Ketoconazole;   Drug: HCG;   Drug: placebo dutasteride;   Drug: placebo ketoconazole
Outcome Measures: Sperm concentration;   IT steroid concentration
18 Recruiting Injection of Hormone to Enhance Implantation in Embryo Transfer After IVF
Condition: Infertility
Intervention: Drug: HCG is introduced
Outcome Measures: HCG enhances pregnancy rate;   implantation rate
19 Unknown  Replacement of Fresh Embryo Transfers (ETs) by Frozen Embryo Transfers (FETs) Using Vitrification
Condition: In Vitro Fertilization
Interventions: Procedure: freezing embryos by vitrification;   Procedure: fresh embryo transfers;   Drug: buserelin;   Drug: recombinant FSH;   Drug: human Chorionic gonadotropin (pregnyl)
Outcome Measures: implantation rate;   on going pregnancy rate
20 Not yet recruiting Phase 3 Trial to Evaluate the Efficacy and Safety of COL-1620 Vaginal Progesterone Gel
Conditions: Luteal Hormone Supplementation in In-vitro Fertilization;   Embryo Transfer
Interventions: Drug: COL-1620;   Drug: Gonadotropin-releasing hormone (GnRH) analogue;   Drug: Follicle-stimulating hormone (FSH);   Drug: Human Chorionic Gonadotropin (hCG)
Outcome Measures: Percentage of subjects with Clinical pregnancy per Embryo Transfer;   Percentage of subjects with Biochemical pregnancy per Embryo Transfer;   Serum progesterone level

These studies may lead to new treatments and are adding insight into Chorionic etiology and treatment.

A major focus of Chorionic research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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