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Clonazepam Medical Research Studies

Up-to-date List of Clonazepam Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Clonazepam Medical Research Studies

Rank Status Study
1 Recruiting Comparison Between Lorazepam, Clonazepam and Clonazepam + Fosphenytoin for the Treatment of Out-of-hospital Generalized Status Epilepticus
Conditions: Status Epilepticus;   Epilepsy
Interventions: Drug: Clonazepam;   Drug: Fosphenytoin;   Drug: Placebo;   Drug: Lorazepam
Outcome Measures: Percentage of patient with a cessation of seizures and absence of recurrence;   Duration between the first cessation and the recurrence of seizures;   Percentage of patients having had a second injection of benzodiazepine;   Percentage of patients having had an injection of the second line treatment;   Percentage of patients having a general anesthesia for refractory status epilepticus;   Percentage of patients having had a side effect;   Percentage of patients having been mechanically ventilated;   Glasgow Coma Scale;   Mortality;   Length of stay in Intensive Care Unit;   Length of stay in hospital
2 Not yet recruiting Clobazam Use in Epilepsia Partialis Continua - Pilot Study
Conditions: Epilepsia Partialis Continua;   Kojewnikov's Epilepsy;   Epilepsy
Interventions: Drug: Clobazam;   Drug: Clonazepam;   Drug: Lorazepam
Outcome Measures: Time (measured in minutes) to onset of seizure freedom;   Reduction of seizure frequency/minute;   Mental status preservation off sedating anticonvulsants as measured by the MoCA© scale;   Ambulatory function as measured by the Hauser Ambulation Index
3 Recruiting Gabapentin Treatment of Benzodiazepine Dependence
Condition: Benzodiazepine Dependence
Interventions: Drug: gabapentin;   Drug: Placebo
Outcome Measure: Abstinence from Benzodiazepine use
4 Unknown  Safety and Tolerability Study of Levetiracetam to Treat Patients With Status Epilepticus
Condition: Status Epilepticus
Intervention: Drug: levetiracetam (add-on)
Outcome Measures: o Uneventful intravenous (iv) administration of study medication;   o Toxicity profile on iv administration, including:;   § Irritation on injection site;   § Hypotension, defined as systolic blood pressure below 90 mm Hg recorded within 24 hours of the dose;   § Cardiac arrest (diagnosed clinically) or bradyarrhythmias including heart block, documented on an electrocardiogram;   § Respiratory depression, defined as the occurrence of apnea or need for intubation;   § Allergic reactions, like skin rash;   § Other side-effects;   Pharmacokinetic parameters of levetiracetam and Clonazepam in patients with SE
5 Unknown  The Efficacy of Botulinum Toxin in Disabling Multiple Sclerosis (MS) Tremor
Conditions: Multiple Sclerosis;   Tremor
Intervention: Drug: Botulinum Toxin Type A
Outcome Measures: A decrease in tremor;   The safety profile of Botulinum Toxin in MS patients

These studies may lead to new treatments and are adding insight into Clonazepam etiology and treatment.

A major focus of Clonazepam research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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