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Colonoscopy Medical Research Studies

Up-to-date List of Colonoscopy Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Colonoscopy Medical Research Studies

Rank Status Study
1 Not yet recruiting Prospective Trial to Compare the Clinical Efficiency of G-EYE™ HD Colonoscopy With Standard HD Colonoscopy
Conditions: Adenoma;   Polyps;   Colorectal Cancer
Interventions: Device: G-EYE™ Colonoscopy;   Device: Standard Colonoscopy
Outcome Measures: G-EYE™ Colonoscopy detection rate of adenomas and serrated lesions compared to the standard Colonoscopy detection rate of the same.;   Number of polyp and adenoma detection, procedure times and safety (number of patients with adverse events.
2 Unknown  Will Cap-Assisted Colonoscopy Improve Performance of Colonoscopy: A Randomized Clinical Trial
Condition: Colonoscopy
Outcome Measures: cap-assisted Colonoscopy compared visibility with standard Colonoscopy;   Polyp detection rate;   Adenoma Detection;   Advanced lesion detection rate;   Cecal Intubation Rate;   Total time for Colonoscopy;   Complication Rate;   Procedure indication
3 Recruiting Effectiveness of Instillation of Blue Water (Indigo Carmin®) for Colonoscopy
Condition: Adenoma Detection to Prevent Colorectal Cancer
Interventions: Device: Colonoscopy with blue Indigo Carmin®;   Device: Standard Colonoscopy with insufflation of air
Outcome Measures: The rate of Colonoscopy with at least one adenoma detected (or adenoma detection rate) confirmed by a histological reporting.;   Measure 1: The characteristics of the lesions detected by the two types of Colonoscopy (diameter, macroscopic appearance, histological nature);   Measure 2 Comparison of the time of the endoscope during the Colonoscopy between the two methods;   Measure 3 The comparison of the tolerance of the two Colonoscopy procedures by assessing patient reported side effects.
4 Recruiting Trial on Innovative Technologies in Colonoscopy
Conditions: Polyps;   Neoplasms;   Inflammatory Bowel Disease
Interventions: Device: Innovative Colonoscopy (Olympus CF-HQ190F, NBI + Dual Focus);   Device: Conventional Colonoscopy (Olympus CF-H180DL)
Outcome Measures: Diagnostic accuracy of innovative Colonoscopy;   Total examination time;   Coecal intubation time;   Pain intensity (VAS scale)
5 Recruiting The Utility of Timed Segmental Withdrawal During Screening Colonoscopy
Condition: Colonoscopy
Intervention: Procedure: Colonoscopy
Outcome Measures: Polyp detection rate (PDR) and Adenoma detection rate (ADR) of patients undergoing a screening Colonoscopy either with segmental withdrawal protocol or with non-segmental withdrawal protocol.;   The Polyp detection rate( PDR) and Adenoma detection rate (ADR) of patients undergoing screening Colonoscopy either with 6-minutes or 8-minutes protocols of the segmental withdrawal.;   The polyp detection rate( PDR) and Adenoma detection rate (ADR) of patients undergoing screening Colonoscopy either with 3-minutes or 4-minutes protocols of the non segmental withdrawal;   Complication rate
6 Not yet recruiting Full Spectrum vs. Standard Forward-viewing Colonoscopy
Condition: Colon Neoplasms
Interventions: Procedure: standard forward-viewing Colonoscopy;   Procedure: full-spectrum Colonoscopy;   Procedure: right colon retroflexion
Outcome Measures: polyp detection rate;   Colonoscopy completion;   procedure time;   adverse events;   endoscopist's satisfaction;   feasibility of the retroflexion in the right colon by trainee;   feasibility of retroflexion in the right colon by the consultant;   patients' satisfaction
7 Recruiting Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
Conditions: Colorectal Neoplasms;   Colonic Polyps;   Colorectal Cancer
Intervention: Device: Technically Improved High Definition NBI Colonoscopy System
Outcome Measures: Nonpolypoid (flat and depressed) colorectal neoplasm detection.;   Assess the number of missed lesions on index Colonoscopy.;   Stratify missed and detected lesion by morphology.;   Impact on surveillance interval recommendations.;   Optical Diagnosis.
8 Recruiting G-Eye Advanced Colonoscopy For Increased Polyp Detection Rate-randomized Tandem Study With Different Endoscopist
Conditions: Colorectal Cancer;   Adenoma
Interventions: Procedure: Standard Colonoscopy;   Procedure: G-EYE(TM) Colonoscopy
Outcome Measures: G-EYE™ Colonoscopy detection rate of adenomas and serrated lesions compared to the standard Colonoscopy detection rate of the same.;   polyp and adenoma detection, procedure times and safety
9 Unknown  Cap-attached Colonoscopy Versus Regular Colonoscopy for Trainees
Conditions: Colonoscopy;   Lower Gastrointestinal Tract
Intervention: Device: Cap-attached Colonoscopy Versus Regular Colonoscopy
Outcome Measures: The success rate of cecal intubation;   The procedure time to achieve cecal intubation;   Success rate in achieving terminal ileum intubation;   The procedure time to achieve terminal ileum intubation;   Complications related to the procedure;   The dose of the intravenous drugs used;   The polyp detection rate
10 Recruiting Screening for Colorectal Cancer With FOBT, Virtual Colonoscopy and Optical Colonoscopy. A Randomized Clinical Trial in the Florence District
Condition: Colorectal Cancer
Intervention: Other: Invitation to screening
Outcome Measures: Participation rate to faecal occult blood test (FOBT), computed tomographic colonography (CTC) and Colonoscopy;   Detection rate for cancer or advanced adenomas of CTC versus three rounds of FOBT every second year;   Referral rate for Colonoscopy induced by primary CTC versus three rounds of FOBT every second year;   Costs of the three different screening strategies proposed;   Expected and perceived burden of Colonoscopy and CTC;   Number and type of complications in all groups
11 Recruiting Prospective Randomized Controlled Trial Comparing Water and Air Colonoscopy in a Community Based Setting
Conditions: Tubular Adenoma;   Colon Cancer;   Hyperplastic Polyp
Interventions: Other: Water Exchange Colonoscopy;   Other: Air Colonoscopy
Outcome Measures: Proximal Adenoma detection;   Total adenoma detection;   Sedation requirements;   Total procedure time;   Cecal intubation time;   Patient position change during procedure;   Use of colonoscope stiffener during procedure;   Abdominal pressure by assistant during procedure;   Length of colonoscope at time of cecal intubation;   Procedure-related pain score;   Reason for air insufflation, and length of colon when air insufflation started, while performing water Colonoscopy;   Volume of water used during water Colonoscopy;   Patient perception regarding air and water Colonoscopy;   Advanced adenoma detection rate;   Type of polypectomy (cold biopsy/cold snare/snare cautery/need for submucosal injection/need for clip placement);   Bowel preparation quality by Boston Bowel Prep Scale;   Post procedure recovery time;   Serrated polyp detection rate;   Procedure time- morning versus afternoon;   Body Mass Index (BMI);   Smoking history;   Alcohol consumption
12 Recruiting Carolina-ColoWrap® in Colonoscopy Performance and Outcomes Study
Condition: Performance and Tolerance of Colonoscopy
Intervention: Device: ColoWrap
Outcome Measures: Mean colonoscopic insertion time;   Frequency of use of ancillary maneuvers;   Frequency of prolonged, difficult cases;   Drug and Dosage Required to Complete Procedure;   Colonoscopy Completion Rate;   Time to patient discharge;   Operator perception of patient discomfort;   Patient Pain, Bloating, and Satisfaction at Discharge;   Operator's Assessment of Procedural Difficultly;   Assistant/Technician's Assessment of Musculoskeletal Pain Following Procedure
13 Recruiting Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy
Condition: Screening Colonoscopy
Intervention: Procedure: Colonoscopy
Outcome Measures: Adenoma Detection Rate, proximal colon and total;   Pain scores;   Sedation requirements
14 Recruiting EndoCuff-assisted Versus Standard Colonoscopy for Polyp Detection
Conditions: Polyp;   Adenoma;   Cancer
Interventions: Device: EndoCuff-assisted Colonoscopy;   Device: Standard Colonoscopy
Outcome Measures: overall polyp detection rate;   adenoma detection rate;   number of LGIN and HGIN adenomas detected;   polyp distribution;   procedure time;   withdrawal time;   ileum intubation rate;   total Colonoscopy rate;   adverse events
15 Recruiting Capsule Versus Conventional Colonoscopy in Patient Following Colorectal Surgery
Condition: Colorectal Cancer
Interventions: Device: PillCam Colon 2;   Procedure: Colonoscopy
Outcome Measures: Number of patients with full colonic exploration and detection of lesions;   Anastomosis visualization;   Number and size of detected lesions;   Quality of colic preparation;   Times related to videocapsule;   Adverse events related to VCC exam and Colonoscopy;   Patient's assessment of tolerability and acceptance;   Health-economic assessment
16 Recruiting Non-anesthesiologist Administered Propofol Sedation for Colonoscopy - a Randomized Clinical Trial
Conditions: Digestive System Diseases;   Colonoscopy Sedation
Interventions: Drug: Non-anesthesiologist propofol sedation;   Drug: Propofol sedation administered by an anesthesiologist;   Procedure: Colonoscopy
Outcome Measures: Minor adverse events;   Propofol dosage;   Patient satisfaction;   Colonoscopy quality indicators;   Patient satisfaction 2
17 Recruiting Experimental Device to Improve Colonoscopy
Conditions: Colonoscopy;   Looping;   Prevent Looping;   Colon Cancer Screening;   Segmental Stiffening Wire
Interventions: Procedure: Colonoscopy;   Procedure: Colon Cancer Screening;   Device: Segmental Stiffening Wire
Outcome Measures: The use of SSW will prevent re-looping of the colonoscope.;   Reduction of colonoscope looping will improve operator and procedural efficiency and patient tolerability of Colonoscopy.
18 Recruiting Randomized Controlled Trial Comparing Water vs. Air Method for Performing Colonoscopy in Adult Female Subjects
Condition: Screening for Colon Cancer
Interventions: Procedure: to infuse water into colon to open the lumen for water infusion Colonoscopy;   Procedure: Air Colonoscopy
Outcome Measures: Cecal intubation;   Amount of opiate and benzodiazepines used for sedation.
19 Unknown  Randomized Controlled Trial Comparing Co2 vs. Air in Colonoscopy in Sedated Patients
Condition: Pain, Satisfaction
Interventions: Other: Air insufflation use in Colonoscopy;   Other: CO2 use in Colonoscopy
Outcome Measures: Pain after Colonoscopy measured by 100mm visual analogue scale.;   patients satisfaction (VAS) and its benefit in regard to cancer screening (2 questions)
20 Recruiting Water-aided Colonoscopy vs Air Insufflation Colonoscopy in Colorectal Cancer Screening
Conditions: Colorectal Cancer;   Colorectal Adenomas;   Colorectal Polyps;   Pain
Interventions: Other: Air insufflation method.;   Other: Water Immersion method.;   Other: Water Exchange method.
Outcome Measures: Adenoma Detection Rate.;   Proximal colon Adenoma Detection Rate.;   Proximal colon <10 mm Adenoma Detection Rate.;   Mean adenomas resected per procedure.;   Cecal intubation rate.;   Cecal intubation time.;   Total procedure time.;   Maximum pain score recorded during insertion phase of Colonoscopy.;   Pain score at discharge.;   Need for sedation/analgesia and its dosage

These studies may lead to new treatments and are adding insight into Colonoscopy etiology and treatment.

A major focus of Colonoscopy research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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