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Confusional Medical Research Studies

Up-to-date List of Confusional Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Confusional Medical Research Studies

Rank Status Study
1 Recruiting The Oslo Study of Clonidine in Elderly Patients With Delirium
Condition: Delirium
Interventions: Drug: Clonidine;   Drug: Placebo
Outcome Measures: MDAS (Memorial delirium assessment scale);   Time-to-first delirium;   Incidence of "full-scale" delirium;   Severity of delirium;   Delirium subtype;   The use of "rescue medication";   Length of hospital stay;   Patient distress;   Side effects of clonidine;   Pharmacokinetic response to clonidine;   Pharmacodynamic response to clonidine;   Biomarkers;   Institutionalization;   Survival;   Cognitive function/ independence
2 Unknown  Brief Delirium Assessments in Non-Intensive Care Unit (ICU) Patients
Condition: Delirium
Intervention:
Outcome Measure:
3 Recruiting TAVI Protocol - Paravertebral Block Study
Conditions: Aortic Valve Replacement;   Aortic Stenosis
Intervention: Other: Thoracic paravertebral block (PVB)
Outcome Measures: Primary Outcome: Dichotomous outcome,number of patients with delirium in the two study groups.;   Hospital length of stay;   Total cost will be compared between the two groups.
4 Recruiting Validation of a French Version of the Confusion Assessment Method (CAM)
Conditions: Confusion;   Delirium
Interventions: Other: Psychiatric evaluation;   Other: Geriatric evaluation
Outcome Measures: CAM French Version: diagnostic properties;   Reliability and quality of the french version of the CAM;   Feasibility of scoring with the French version of the Delirium Index;   Diagnostic properties of alternative algorithms constructed from items of CAM (French version)
5 Unknown  Preventing ICU Subsyndromal Delirium Conversion to Delirium With Haloperidol
Condition: Subsyndromal Delirium
Interventions: Drug: Haloperidol decanoate;   Drug: Placebo
Outcome Measures: Conversion from subsyndromal delirium to delirium during the period of study drug administration (up to 10 days).;   The number of hours spent agitated (SAS >/=5) as percent of time study drug administered (up to 10 days).;   Duration of mechanical ventilation.;   Clinically significant QTc interval prolongation (≥ 500 msec or an increase of more than 60msec above baseline);   Extrapyramidal effects (as evidenced by a positive Simpson-Angus Scale Score);   The number of hours spent excessively sedated (SAS ≤ 2) as a percent of time study drug administered (up to 10 days).;   Cognition, incidence of anxiety, incidence of depressive symptoms, quality of life (ie., functional status and emotional well being)and sleep quality.
6 Recruiting Impact of the Use of the Scale ALGOPLUS® on the Prescriptions of Analgesics in Emergency Department on Patients of 75 Years Old or More
Condition: Pain
Intervention: Other: pain in elderly patients
Outcome Measures: Collection of the rate of prescription of analgesic treatments;   Collection of the score of quotation of pain by numerical scale (score from 0 to 10);   Collection of prescription of analgesic;   Collection of the prescription of analgesic by class according to the scale of the WHO;   Collection of the score of the scale Algoplus®

These studies may lead to new treatments and are adding insight into Confusional etiology and treatment.

A major focus of Confusional research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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