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Conivaptan Medical Research Studies

Up-to-date List of Conivaptan Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Conivaptan Medical Research Studies

Rank Status Study
1 Unknown  Comparing the Effects of Conivaptan and Diuretics on Plasma Neurohormones and Renal Blood Flow in Patients With Chronic Congestive Heart Failure
Condition: Heart Failure
Interventions: Drug: Conivaptan;   Drug: Furosemide;   Drug: Conivaptan and furosemide
Outcome Measures: renal hemodynamics renal blood flow and glomerular filtration rate;   measure plasma neurohormone levels
2 Not yet recruiting Effects on Exercise Hemodynamics of Vasopressin Blockade by Conivaptan Infusion in Heart Failure Patients
Condition: Heart Failure
Interventions: Drug: Conivaptan;   Drug: Placebo (Dextrose)
Outcome Measures: The joint endpoint of change in pulmonary capillary wedge pressure (PCWP) and cardiac output (CO) at the submaximal exercise intensity of 50 % of the maximal exercise capacity;   Cardiac index (CI) during submaximal exercise from rest to submaximal exercise;   Pulmonary and systemic vascular resistance from rest to submaximal exercise;   Left ventricular end diastolic diameter during exercise from rest to submaximal exercise;   The change in mean pulmonary artery pressure (mPAP) from rest to submaximal exercise;   The change in BNP, MR-ANP and copeptin from rest to submaximal exercise
3 Not yet recruiting Study of Stroke Related Edema Treatments
Conditions: Acute Cerebrovascular Accident;   Cerebral Edema
Interventions: Drug: Conivaptan;   Drug: Hypertonic saline;   Drug: Mannitol
Outcome Measures: Modified Rankin Score;   National Institutes of Health Stroke Severity (NIHSS) scale;   Neurological status of the subject;   All cause mortality data

These studies may lead to new treatments and are adding insight into Conivaptan etiology and treatment.

A major focus of Conivaptan research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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