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Copd Medical Research Studies

Up-to-date List of Copd Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Copd Medical Research Studies

Rank Status Study
1 Unknown  Effects of Transcutaneous Electrical Diaphragmatic Stimulation on Respiratory Variables in COPD Patients
Condition: COPD
Interventions: Other: TEDS in COPD patients;   Other: TEDS in healthy patients
Outcome Measures: Respiratory muscle strength and spirometry;   Respiratory pattern
2 Unknown  Evaluation of Utility Quadriceps Magnetic Stimulation in COPD (Chronic Obstructive Pulmonary Disease) Patients After Hospital Exacerbation
Conditions: COPD;   COPD Exacerbation
Intervention: Device: Repetitive magnetic stimulation of the quadriceps muscle
Outcome Measures: Six minute walking distance;   quality of life CRQ;   Maximal voluntary contraction of the quadriceps
3 Recruiting Effects of Ergometer Training With Telemonitoring in Patients With Chronic Obstructive Pulmonary Disease (COPD) After Exacerbation
Condition: COPD
Interventions: Other: Ergometer Training;   Other: Motivation
Outcome Measures: Training time;   BODE-Index
4 Recruiting Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and COPD Exacerbations in Patients With Moderate to Very Severe COPD
Conditions: COPD;   Chronic Obstructive Pulmonary Disease
Interventions: Drug: Aclidinium Bromide;   Drug: Placebo
Outcome Measures: Time to first Major Adverse Cardiovascular Event (MACE);   Rate of moderate or severe COPD exacerbations per patient per year during the first year of treatment;   Rate of hospitalizations due to COPD exacerbation per patient per year during the first year of treatment;   Time to first Major Adverse Cardiovascular Event (MACE) or other serious cardiovascular events of interest
5 Recruiting Effects of Occupational Therapy in COPD
Condition: Chronic Obstructive Pulmonary Disease
Intervention: Other: Occupational therapy
Outcome Measures: Functionality;   Quality of life;   Anxiety and depression;   Activity levels;   Dyspnoea
6 Recruiting Soins intégrés BPCO (Broncho-pneumopathie Chronique Obstructive) en Valais - Mieux Vivre Avec ma BPCO (COPD Integrated Care Program Valais - Living Well With COPD)
Condition: Chronic Obstructive Pulmonary Disease (COPD)
Intervention: Other: COPD integrated care
Outcome Measures: Generic and disease-specific health-related quality-of-life (Chronic Respiratory Questionnaire (CRQ), SF-36, COPD Assessment Test (CAT));   All-cause hospitalizations (past 12 months);   Processes of care, patient assessment of chronic illness care (PACIC);   6-minutes walking test;   COPD exacerbations;   % smokers
7 Recruiting Behavioral Intervention to Maintain Physical Capacity and Activity in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Behavioral: Behavioural intervention;   Behavioral: Usual care group
Outcome Measures: Six-minute walking distance;   Physical activity level;   Short Form 36;   Chronic Respiratory Disease Questionnaire;   Hospital anxiety and depression scale;   Grippit
8 Recruiting Cognitive Status in Chronic Obstructive Pulmonary Disease's Patients
Condition: Chronic Obstructive Pulmonary Disease
Intervention: Other: Cognitive assessment
Outcome Measures: Cognitive impairment;   Sleep quality;   Activity monitoring;   Nutritional state;   Quality of life;   Cough;   Comorbidities;   Anxiety and depression;   Cognitive flexibility;   Forced vital capacity;   Forced expiratory volume in the first second
9 Recruiting Muscle Training Induced Angiogenesis in COPD
Conditions: Peripheral Muscle Dysfunction;   COPD
Interventions: Procedure: Muscular biopsy;   Other: 5-10 weeks sport training
Outcome Measures: Capillary-o-fiber ratio assessed by immunochemistry on a muscle biopsy of the vastus lateralis of the quadriceps;   quadriceps endurance;   mitochondrial density;   muscle citrate synthase activity
10 Recruiting Endothelial Function Study Before Cardiovascular Surgery
Conditions: Chronic Obstructive Pulmonary Disease (COPD);   Obstructive Sleep Apnea Syndrome (OSAS)
Intervention:
Outcome Measures: The primary endpoint is the percent of peripheral arterial tone (PAT) in COPD and/or OSAS patients compared to non COPD non OSAS patients.;   Evaluation of the systemic inflammation, insulin-resistance and oxidative stress occurring during COPD and/or OSAS patients compared to non COPD non OSAS patients.;   Evaluation of adipose tissue inflammation and oxidative stress occurring during COPD and/or OSAS patients compared to non COPD non OSAS patients.;   Polysomnography;   Functional respiratory exploration
11 Recruiting BEAM COPD: Breathing, Education, Awareness and Movement in Chronic Obstructive Pulmonary Disease (COPD)
Condition: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Behavioral: Tai chi;   Behavioral: Mind-body breathing;   Behavioral: Education
Outcome Measures: Feasibility of tai chi intervention;   Change from baseline- Disease specific quality of life;   Change from baseline- Exercise capacity;   Change from baseline- Dyspnea;   Change from baseline- Psychosocial well-being;   Change from baseline- Pulmonary function;   Change from baseline- Physical strength and flexibility
12 Unknown  The Effect on Small Airways of Addition of Theophylline as Inducer of Histone Deacilase Activity for Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD), Treated With Inhaled Steroids and Long Acting Beta Agonists
Condition: COPD
Interventions: Drug: Theophylline;   Drug: Placebo
Outcome Measures: Air trapping;   endurance time
13 Not yet recruiting The PALP™-COPD Trial (Low-Flow CO2-Removal (ECCO2-R) in Exacerbated COPD)
Conditions: COPD;   Chronic Obstructive Pulmonary Disease
Intervention: Device: CO2-Removal (PALP-Device/MaquetCP)
Outcome Measure: Difference in time of mechanical ventilation
14 Unknown  AVAPS-AE Algorithm in Chronic Obstructive Pulmonary Disease (COPD)Patients
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Device: AVAPS-AE;   Device: AVAPS-AE mode of ventilator therapy
Outcome Measures: Change in TCO2 measurement from baseline to 2 weeks post AVAPS-AE mode of therapy and change in TCO2 measurement from baseline to 6 weeks post AVAP-AE mode of therapy;   Actigraphy;   Six Minute Walk test;   Spirometry;   Nocturnal Capnography (TcC02);   Nocturnal oximetry (Sp02);   Daily Sleep Log;   Severe Respiratory Insufficiency Questionnaire;   COPD Assessment Test- CAT;   MRC Dyspnea Questionnaire
15 Not yet recruiting "Consultation Liaison and Integrated Care for COPD Patients With Psychiatric Co-Morbidity"
Conditions: Chronic Obstructive Pulmonary Disease;   Anxiety;   Depression
Interventions: Procedure: Integrated care;   Procedure: Usual control
Outcome Measures: HADS score;   Resource use and direct costs of care
16 Not yet recruiting Novel Vascular Manifestations of Chronic Obstructive Pulmonary Disease
Condition: COPD
Intervention:
Outcome Measures: Fractional Anisotropy;   Aortic Pulse Wave Velocity;   MRI Cerebral Perfusion - ASL;   Cerebral Microbleeds;   Cognitive Function;   Cardiac MRI;   FEV1 % predicted;   Arterial Oxygen Saturation;   Retinal Photography;   Micro-albuminuria;   Health Status
17 Recruiting Efficacy of Serum Bovine Immunoglobulin in Improving Nutritional Status in Advanced COPD
Condition: Advanced COPD (GOLD Stage 3 or 4) With Cachexia
Interventions: Dietary Supplement: Serum bovine immunoglobulin (SBI) medical food;   Dietary Supplement: Placebo (for serum bovine immunoglobulin)
Outcome Measures: The subtracted differences in BMI, body fat measurement, and grip strength between participants receiving SBI or placebo at baseline and 6 months.;   The subtracted differences between FEV1 and COPD Assessment Test scores in patients receiving SBI or placebo at baseline and 6 months.
18 Not yet recruiting A Behavioral Therapy for Insomnia Co-existing With COPD
Conditions: Insomnia;   COPD;   Chronic Obstructive Pulmonary Disease;   Fatigue
Interventions: Behavioral: Cognitive Behavioral Therapy for Insomnia;   Behavioral: COPD Education;   Behavioral: Attention Control
Outcome Measures: Insomnia;   Fatigue;   Beliefs about sleep;   Sleep habits;   Self-efficacy for sleep;   Self-efficacy for COPD management;   Emotional arousal;   Inflammation;   Pulmonary function;   Daytime functioning
19 Recruiting A Pragmatic Cluster Trial of a Tailored Intervention to Improve COPD Management
Condition: Chronic Obstructive Pulmonary Disease (COPD)
Intervention: Other: Implementation educational programme
Outcome Measures: The percentage of selected patients receiving anti-tabacco counseling recorded by the GPs in the labeled patients' medical records.;   Health outcomes in patients' medical records.
20 Recruiting Swiss Chronic Obstructive Pulmonary Disease (COPD) Management Cohort
Conditions: Chronic Obstructive Pulmonary Disease;   COPD Exacerbation
Intervention:
Outcome Measures: Number of exacerbation;   Disease progression

These studies may lead to new treatments and are adding insight into Copd etiology and treatment.

A major focus of Copd research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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