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Cormax Medical Research Studies

Up-to-date List of Cormax Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Cormax Medical Research Studies

Rank Status Study
1 Recruiting Clobetasol for Oral Graft-Versus-Host Disease
Condition: Oral Chronic Graft vs Host Disease
Interventions: Drug: Clobetasol Oral Rinse;   Procedure: Chronic GVHD organ staging;   Procedure: Assessment of Oral GVHD;   Behavioral: Numeric rating scales for oral pain;   Behavioral: Oral Global Scale;   Behavioral: Painometer (POM) Assessment;   Behavioral: Oral Health Impact Profile-OHIP-14;   Procedure: Biopsy of buccal mucosa;   Procedure: Short ACTH stimulation test
Outcome Measures: To investigate efficacy of topical clobetasol 0.05% oral rinse for oral chronic graft-versus-host-disease (cGVHD) during a four-week treatment period as assessed by Oral Mucositis Rating Scale (OMRS).;   To assess the effect of topical clobetasol on oral cGVHD related pain, sensitivity, and dryness.;   To evaluate the basic pharmacodynamics and pharmacokinetics of clobetasol mouth rinse in cGVHD patients.
2 Recruiting Safety and Efficacy Study of Combination Treatment With Excimer Laser, Clobex Spray, and Vectical Ointment in the Treatment of Psoriasis
Condition: Chronic Stable Plaque Psoriasis
Interventions: Drug: Clobex Spray;   Drug: Vectical Ointment;   Procedure: Excimer Laser
Outcome Measures: The primary endpoint will be the percentage of patients achieving PASI-75 response at week 12.;   The secondary endpoint will be the percentage of patients achieving PASI-75 at weeks 4 and 8.;   A tertiary endpoint will be the percentage of patients achieving PASI-90 at weeks 4, 8, and 12.
3 Unknown  Safety and Efficacy of Clobetasol Propionate 0.05% E Foam in Alopecia
Condition: Alopecia
Intervention: Drug: Clobetasol Propionate 0.05% Emollient Foam
Outcome Measures: Improvement of pruritis, tenderness, and pain;   Absence of inflammation on biopsy
4 Recruiting Progesterone vs Clobetasol Propionate in Vulvar Lichen Sclerosus
Condition: Vulvar Lichen Sclerosus
Interventions: Drug: Clobetasol propionate 0.05%;   Drug: Progesterone 8%
Outcome Measures: Score of the characteristics of Lichen sclerosus based on vulvar efflorescences;   Patient-reported symptoms;   Quality of life;   Adverse events
5 Recruiting Comparison Between Corticosteroid and Topical Steroids in the DRESS
Condition: Drug Rash With Eosinophilia and Systemic Symptoms
Interventions: Drug: Prednisone;   Drug: Clobetasol
Outcome Measures: Rate of patients with a complete or almost healing of visceral involvement to D30 +/- 5 days AND complete or almost complete healing of skin involvement.;   Rate of patients with a complete or almost complete healing of cutaneous and visceral involvement at Day 30 ± 5 days;   Delays of complete or almost complete visceral healing;   Relapse rates and bounces rates between the end of acute treatment and M12;   Patients rate evaluating to severe form (occurrence of a criterion defining the severe form cf. Above);   Occurrence rate of moderate DRESS visceral involvement, during the initial treatment (D0 to D30) not existing at inclusion;   Mortality rate at Month 12;   Sequelae rate at Month 12;   Systemic steroids adverse reactions rate;   Topical steroids adverse reactions rate;   Patch tests evaluation in DRESS;   Reactivation kinetics of Cytomegalovirus (CMV), Epstein-Barr virus (EBV), Herpes Simplex virus (HSV), Human Herpes virus6 (HHV6) and Human Herpes virus7 (HHV7);   Predictive value of lymphocyte transformation test in imputability;   Immunological factors evaluation in the skin;   Blood inflammatory cytokines and chemokines analysis;   Blood cytokines polymorphisms analysis
6 Not yet recruiting Dapsone Prurigo Study
Condition: Lichen Simples Chronicus and Prurigo
Intervention: Drug: Dapsone gel - verum
Outcome Measures: Pruritus based on visual analogue scale in side to side comparison;   5 D itch scale in side to side comparison
7 Not yet recruiting Treatment of Granuloma Umbilical in Newborn Babies
Condition: Fetus or Newborn Affected by Condition of Umbilical Cord
Interventions: Procedure: silver nitrate;   Drug: Steroids;   Procedure: alcohol
Outcome Measure: Duration of treatment
8 Not yet recruiting An Open Label Phase II Trial of Topical Sirolimus for the Treatment of Refractory Oral Chronic Graft-versus-Host-Disease
Conditions: Chronic Graft-versus-Host-Disease;   Oral Mucosal Disease Due to Graft-versus-host Disease
Intervention: Drug: Sirolimus
Outcome Measures: Percentage of Participants with a Subjective Sensitivity Score Response;   Oral Health QOL Assessment

These studies may lead to new treatments and are adding insight into Cormax etiology and treatment.

A major focus of Cormax research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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