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DRAIN Medical Research Studies

Up-to-date List of DRAIN Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest DRAIN Medical Research Studies

Rank Status Study
1 Recruiting Prospective Randomized Study of PTC and EUS-guided DRAINAGE of the Bile Duct
Condition: Jaundice
Interventions: Device: biliary DRAINAGE;   Device: EUS guided biliary DRAINAGE
Outcome Measures: Morbidity rate;   efficacy;   feasibility;   biliary DRAINAGE duration;   quality of life
2 Recruiting DRAINAGE After Rectal Excision for Rectal Cancer
Conditions: Rectal Cancer Surgery;   Randomized Clinical Trial;   Multicenter Study;   Pelvic DRAINAGE
Interventions: Procedure: Laying and management of the drain (strictly randomized arm with DRAINAGE);   Procedure: No pelvic DRAINAGE
Outcome Measures: Pelvic sepsis;   Overall sepsis;   Peri-operative mortality;   Surgical morbidity according to Dindo classification;   Re-surgery during the hospitalization;   Rate of closure of stoma
3 Recruiting A Prospective Randomized Study Evaluating the Recurrence Rate of Chronic Subdural Hematoma After Placing a Subperiosteal DRAINAGE Compared to a Subdural DRAINAGE
Condition: Chronic Subdural Hematoma
Interventions: Procedure: Subdural DRAINAGE;   Procedure: Subperiosteal DRAINAGE
Outcome Measures: Recurrence Rate;   Complication rate (Morbidity);   Mortality;   Outcome: Markwalder Score;   Outcome: modified Ranking Score;   Outcome: Glasgow Outcome Score
4 Not yet recruiting Randomized Study Comparing Pleural DRAINAGE by Videothoracoscopy to Medical DRAINAGE in Infectious Pleural Effusion
Condition: Infectious Pleural Effusion
Interventions: Device: Videothoracoscopy DRAINAGE;   Drug: Medical DRAINAGE
Outcome Measure: Hospital Stay in days
5 Unknown  EARLYdrain - Outcome After Early Lumbar CSF-DRAINAGE in Aneurysmal SAH
Condition: Aneurysmal Subarachnoid Hemorrhage
Intervention: Procedure: Insertion of a lumbar drain
Outcome Measures: Disability in Lumbar DRAINAGE group (LD) vs. disability in control group (No-LD);   mortality;   Modified Rankin scale (mRS) score as continuous variable;   Angiographically determined vasospasm;   Vasospastic infarction;   Expression of clinical delayed neurological deficit;   Transcranial duplex ultrasound measured flow velocity in both middle cerebral arteries;   Early mortality;   Rate of CSF shunt insertion in the first six months;   Presence of CSF infection
6 Recruiting Effect of Intermittent Versus Continuous Subglottic Secretion DRAINAGE on Tracheal Mucosa Damages
Condition: Mechanical Ventilation Complication
Interventions: Device: Intermittent subglottic secretion DRAINAGE;   Device: Continuous subglottic secretion DRAINAGE
Outcome Measures: Tracheal mucosal damages assessed by tracheal fibroscopy.;   Volume of daily secretions;   Occurrence of difficulties or impossibilities of secretion DRAINAGE;   Occurrence of ventilator-associated pneumonia
7 Unknown  Active Versus Non Active DRAINAGE for the Treatment of Infected Intra-abdominal Collection
Conditions: Surgery;   Pancreatitis;   Diverticulitis;   Appendicitis
Intervention: Procedure: Percutaneous DRAINAGE of intra-abdominal collection
Outcome Measures: time of DRAINAGE;   Control of infection;   Timing of antibiotherapy;   Hospital stay;   Morbidity related to the procedure;   in-hospital mortality
8 Not yet recruiting READI (Readiness Evaluation And Discharge Interventions): Implementation as a Standard Nursing Practice for Hospital Discharge
Condition: Discharge Transition of Patients Discharged to Home
Interventions: Other: RN-RHDS protocol;   Other: RN-RHDS+PT-RHDS protocol;   Other: RN-RHDS + PT-RHDS + NIAF
Outcome Measures: Post-discharge Utilization within 30 days after hospital discharge;   Nurse Initiated Action Form
9 Recruiting Prospective Random Comparing Study on EUS-guided Pseudocyst DRAINAGE by Naso-pancreatic Tube and Stents
Condition: Pancreatic Pseudocyst
Intervention: Procedure: EUS-guided pancreatic pseudocyst DRAINAGE
Outcome Measures: recurrence rate of pancreatic pseudocyst;   The complication rate
10 Recruiting Drug-Related Problems and Healthcare Utilization Post-Hospital Discharge
Conditions: Drug Related Problems Post Hospital Discharge;   Healthcare Utilization;   Discharge Medication Counseling
Interventions: Other: RPh Counseling + Outpatient Med Dispensing at Discharge;   Other: Discharge Med Dispensing Plus Counseling - Current Practice
Outcome Measures: Drug-related problems (composite of adverse drug reactions, drug interactions, and failure to receive drugs) during the first 30 days post-hospital discharge;   Healthcare utilization;   Hospital readmissions;   Treatment delays
11 Recruiting External DRAINAGE Versus Internal DRAINAGE of Pancreatic Duct With a Stent After Pancreaticoduodenectomy (EDIDPD)
Conditions: Postoperative Fistula;   Complications of Surgical and Medical Care: General Terms
Intervention: Procedure: Internal DRAINAGE of Pancreatic Duct after pancreatomy
Outcome Measures: the rate of Postoperative pancreatic fistula within 2 weeks after operation;   the rate of postoperative Surgical Complications
12 Unknown  Preoperative Biliary DRAINAGE for Resectable Hilar Cholangiocarcinoma
Conditions: Cholangiocarcinoma;   DRAINAGE;   Surgery
Intervention: Procedure: Preoperative biliary DRAINAGE
Outcome Measures: Incidence of postoperative complication;   Postoperative mortality;   Overall survival, OS;   Disease free survival, DFS
13 Recruiting Impact of Manual Lymphatic DRAINAGE on Postoperative Edema of the Face and the Neck After Orthognathic Surgery
Conditions: Maxillofacial Abnormalities;   Post Procedural Discharge
Intervention: Other: Manual Lymphatic DRAINAGE
Outcome Measures: Assessment of edema using a centimeter scale.;   Comfort criteria;   mental well-being.
14 Unknown  Efficacy of a Web-based Seamless Discharge Tool
Condition: Acute Exacerbation of Chronic Obstructive Airways Disease
Interventions: Procedure: seamless discharge;   Procedure: Usual care
Outcome Measures: readmission to hospital;   Post-discharge mortality
15 Recruiting Effects of Early Stage Mini-invasive Abdominal DRAINAGE on Complications and Prognosis of SAP
Condition: Pancreatitis
Interventions: Other: Early stage abdominal DRAINAGE;   Other: Late stage abdominal DRAINAGE
Outcome Measures: Rates of ACS in 28 days since outbreaks;   Rates of surgical interfere, MODS or death in 6 months since outbreaks
16 Recruiting Laparotomy vs. DRAINAGE for Infants With Necrotizing Enterocolitis
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Enterocolitis, Necrotizing;   Intestinal Perforation
Interventions: Procedure: Laparotomy;   Procedure: DRAINAGE
Outcome Measures: Death or neurodevelopmental impairment;   Surgical complications;   Number of surgical procedures;   Sepsis episodes;   Duration of parenteral nutrition;   Parenteral nutrition associated cholestasis;   Length of hospital stay;   Rehospitalizations
17 Recruiting Comparison Between Internal and External Preoperative Biliary DRAINAGE in Periampullary Cancers
Conditions: Periampullary Cancers Causing Obstructive Jaundice;   Pancreas Head Cancer;   Bile Duct Cancer;   Ampulla of Vater Cancer
Intervention: Procedure: biliary DRAINAGE
Outcome Measures: Incidence of infectious complications after biliary DRAINAGE;   Effect of reducing serum total bilirubin after DRAINAGE;   Peritumoral inflammatory reaction after DRAINAGE;   Fibrosis of the bile duct;   Difficulties in dissection around the tumor
18 Unknown  Early (4 Days) Versus Standard DRAINAGE of the Abdominal Cavity After Pancreaticoduodenectomy
Conditions: Pancreatic Disease;   Pancreatic Neoplasms
Interventions: Procedure: Drain removal at D4;   Procedure: Standard drain removal
Outcome Measure: Surgical Site Infection at D30
19 Not yet recruiting The Effect of Subdural Drain Placement After Burr Hole Evacuation of Chronic Subdural Haematomas on Recurrence: a Prospective Randomised-controlled Multi-centre Study
Conditions: Chronic Subdural Hematoma;   Subdural Drain
Intervention: Device: Silicon subdural drain placement after burr hole evacuation of chronic subdural hematoma
Outcome Measures: Significant recurrent chronic subdural hematoma i.e. requiring repeat operative DRAINAGE at six months after the primary operation;   1. Functional performance in terms of the Extended Glasgow Outcome Scale;   Added neurological deficit;   Surgery-related complications;   Death;   Modified Rankin Score
20 Recruiting Use of Lumbar Drain to Remove Clots in Patients Admitted to the Neuro-ICU After Subarachnoid Hemorrhage.
Condition: Subarachnoid Hemorrhage.
Interventions: Procedure: Lumbar drain;   Procedure: Ventricular drain
Outcome Measures: Accumulated Hb and bilirubin in CSF DRAINAGE;   placement of a ventriculoperitoneal shunt;   Lindegaard ratio (TCD) > 3;   clinical signs of vasospasms

These studies may lead to new treatments and are adding insight into DRAIN etiology and treatment.

A major focus of DRAIN research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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